Anthony G Wilson

Anthony G Wilson

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Anthony G Wilson

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Patient and public involvement in biomedical research: training is not a substitute for relationship building.

Ann Rheum Dis 2019 Jul 12. Epub 2019 Jul 12.

UCD Centre for Arthritis Research, School of Medicine, University College Dublin, Dublin, Ireland

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http://dx.doi.org/10.1136/annrheumdis-2019-215595DOI Listing
July 2019

Facilitating public and patient involvement in basic and preclinical health research.

PLoS One 2019 14;14(5):e0216600. Epub 2019 May 14.

UCD Centre for Arthritis Research, School of Medicine, UCD Dublin, Dublin, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216600PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516642PMC
May 2019

The Autoimmune Susceptibility Gene Regulates Macrophage-Mediated Resolution of Inflammation.

J Immunol 2019 Feb 18;202(4):1069-1078. Epub 2019 Jan 18.

University College Dublin Centre for Arthritis Research, Conway Institute, University College Dublin, Dublin D04 W6F6, Ireland.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801155
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http://dx.doi.org/10.4049/jimmunol.1801155DOI Listing
February 2019

Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis.

Pharmacogenomics J 2018 09 31;18(5):657-664. Epub 2018 Aug 31.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/s41397-018-0040-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150911PMC
September 2018

Autoimmune-autoinflammatory rheumatoid arthritis overlaps: a rare but potentially important subgroup of diseases.

RMD Open 2017 1;3(2):e000550. Epub 2017 Nov 1.

Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1136/rmdopen-2017-000550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687541PMC
November 2017

The role of genetic analysis for predicting outcome of rheumatoid arthritis.

Expert Rev Mol Diagn 2017 09 19;17(9):809-814. Epub 2017 Jul 19.

a School of Medicine , UCD Conway Institute of Biomolecular and Biomedical Research , Dublin , Ireland.

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http://dx.doi.org/10.1080/14737159.2017.1355732DOI Listing
September 2017

DNA methylation as a marker of response in rheumatoid arthritis.

Pharmacogenomics 2017 Sep 24;18(14):1323-1332. Epub 2017 Aug 24.

Arthritis Research UK Centre for Genetics & Genomics, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.2217/pgs-2016-0195DOI Listing
September 2017

The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort.

Rheumatology (Oxford) 2017 06;56(6):1019-1024

Arthritis Research UK, Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, The University of Manchester.

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http://dx.doi.org/10.1093/rheumatology/kew387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445600PMC
June 2017

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort.

Ann Rheum Dis 2017 Jan 31;76(1):208-213. Epub 2016 May 31.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-208849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264213PMC
January 2017

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels.

Rheumatology (Oxford) 2016 Nov 25;55(11):2050-2055. Epub 2016 Aug 25.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088626PMC
November 2016

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.

Arthritis Rheumatol 2016 06 21;68(6):1353-60. Epub 2016 Apr 21.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, and Central Manchester NHS Trust, and Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/art.39590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914881PMC
June 2016

Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort.

Pharmacogenomics 2016 05 16;17(7):715-20. Epub 2016 May 16.

Arthritis Research UK, Centre for Genetics & Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.2217/pgs.16.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996314PMC
May 2016

Histone deacetylase 1 regulates tissue destruction in rheumatoid arthritis.

Hum Mol Genet 2015 Oct 7;24(19):5367-77. Epub 2015 Jul 7.

Department of Infection and Immunity, University of Sheffield, Sheffield S10 2RX, UK and Conway Institute, Belfield Campus, University College Dublin, Dublin 4, Ireland

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http://dx.doi.org/10.1093/hmg/ddv258DOI Listing
October 2015

C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis.

Proc Natl Acad Sci U S A 2015 Sep 27;112(37):11618-23. Epub 2015 Aug 27.

Academic Unit of Rheumatology, University of Sheffield, Sheffield S10 2RX, United Kingdom; Department of Rheumatology, Dublin Academic Medical Centre and the Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin D04 W6F6, Ireland;

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http://dx.doi.org/10.1073/pnas.1501947112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577169PMC
September 2015

Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.

Arthritis Rheumatol 2015 May;67(8):2011-9

Darren Plant, PhD, Anne Barton, MBChB, PhD, FRCP: Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, and NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, UK.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://doi.wiley.com/10.1002/art.39169
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http://dx.doi.org/10.1002/art.39169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843946PMC
May 2015

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

JAMA 2015 Apr;313(16):1645-56

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, England2NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manches.

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http://dx.doi.org/10.1001/jama.2015.3435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928097PMC
April 2015

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Rheumatology (Oxford) 2015 Mar 10;54(3):494-9. Epub 2014 Sep 10.

Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, UK. Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/keu358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334684PMC
March 2015

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

Lancet 2015 Feb;385 Suppl 1:S48

Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, UK.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://linkinghub.elsevier.com/retrieve/pii/S014067361560363
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http://dx.doi.org/10.1016/S0140-6736(15)60363-4DOI Listing
February 2015

Genetic and epigenetic predictors of responsiveness to treatment in RA.

Nat Rev Rheumatol 2014 Jun 18;10(6):329-37. Epub 2014 Feb 18.

Arthritis Research UK Centre of Excellence for Musculoskeletal Genetics, Manchester Academy of Health Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1038/nrrheum.2014.16DOI Listing
June 2014

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach.

Ann Rheum Dis 2014 May 9;73(5):938-40. Epub 2013 Dec 9.

Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, , Manchester, UK.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20444
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http://dx.doi.org/10.1136/annrheumdis-2013-204443DOI Listing
May 2014

The emerging role of epigenetics in rheumatic diseases.

Rheumatology (Oxford) 2014 Mar 11;53(3):406-14. Epub 2013 Sep 11.

Department of Infection and Immunity, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK.

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http://dx.doi.org/10.1093/rheumatology/ket292DOI Listing
March 2014

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

PLoS Genet 2013 19;9(9):e1003808. Epub 2013 Sep 19.

Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, King's College London, London, United Kingdom ; Department of Medical and Molecular Genetics, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1003808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778023PMC
March 2014

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

Arthritis Rheumatol 2014 Jan;66(1):24-30

Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, and NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/art.38196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285161PMC
January 2014

Metaanalysis of the association of smoking and PTPN22 R620W genotype on autoantibody status and radiological erosions in rheumatoid arthritis.

J Rheumatol 2013 Jul 1;40(7):1048-53. Epub 2013 May 1.

School of Health and Related Research, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.3899/jrheum.120784DOI Listing
July 2013

The role of histone deacetylases in rheumatoid arthritis fibroblast-like synoviocytes.

Biochem Soc Trans 2013 Jun;41(3):783-8

Academic Unit of Rheumatology, Department of Infection and Immunity, The Medical School, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST20130053
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http://dx.doi.org/10.1042/BST20130053DOI Listing
June 2013

Relationship between area-level socio-economic deprivation and autoantibody status in patients with rheumatoid arthritis: multicentre cross-sectional study.

Ann Rheum Dis 2012 Oct 22;71(10):1640-5. Epub 2012 Mar 22.

NIHR-Leeds Biomedical Research Unit, Leeds Institute of Molecular Medicine, Level 8, Wellcome Trust Brenner Building, St. James's University Hospital, Leeds, LS9 7TF, UK.

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http://dx.doi.org/10.1136/annrheumdis-2011-201003DOI Listing
October 2012

Nocturnal sleep enhances working memory training in Parkinson's disease but not Lewy body dementia.

Brain 2012 Sep 20;135(Pt 9):2789-97. Epub 2012 Aug 20.

Department of Neurology, Program in Sleep Medicine, Emory University School of Medicine, 1841 Clifton Road, Room 506, Atlanta, GA 30329, USA.

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http://dx.doi.org/10.1093/brain/aws192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577106PMC
September 2012

Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.

Hum Mutat 2012 Apr 28;33(4):741-9. Epub 2012 Feb 28.

NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1002/humu.22031DOI Listing
April 2012

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.

Authors:
Nadeem Sarwar Adam S Butterworth Daniel F Freitag John Gregson Peter Willeit Donal N Gorman Pei Gao Danish Saleheen Augusto Rendon Christopher P Nelson Peter S Braund Alistair S Hall Daniel I Chasman Anne Tybjærg-Hansen John C Chambers Emelia J Benjamin Paul W Franks Robert Clarke Arthur A M Wilde Mieke D Trip Maristella Steri Jacqueline C M Witteman Lu Qi C Ellen van der Schoot Ulf de Faire Jeanette Erdmann Heather M Stringham Wolfgang Koenig Daniel J Rader David Melzer David Reich Bruce M Psaty Marcus E Kleber Demosthenes B Panagiotakos Johann Willeit Patrik Wennberg Mark Woodward Svetlana Adamovic Eric B Rimm Tom W Meade Richard F Gillum Jonathan A Shaffer Albert Hofman Altan Onat Johan Sundström Sylvia Wassertheil-Smoller Dan Mellström John Gallacher Mary Cushman Russell P Tracy Jussi Kauhanen Magnus Karlsson Jukka T Salonen Lars Wilhelmsen Philippe Amouyel Bernard Cantin Lyle G Best Yoav Ben-Shlomo JoAnn E Manson George Davey-Smith Paul I W de Bakker Christopher J O'Donnell James F Wilson Anthony G Wilson Themistocles L Assimes John-Olov Jansson Claes Ohlsson Åsa Tivesten Östen Ljunggren Muredach P Reilly Anders Hamsten Erik Ingelsson Francois Cambien Joseph Hung G Neil Thomas Michael Boehnke Heribert Schunkert Folkert W Asselbergs John J P Kastelein Vilmundur Gudnason Veikko Salomaa Tamara B Harris Jaspal S Kooner Kristine H Allin Børge G Nordestgaard Jemma C Hopewell Alison H Goodall Paul M Ridker Hilma Hólm Hugh Watkins Willem H Ouwehand Nilesh J Samani Stephen Kaptoge Emanuele Di Angelantonio Olivier Harari John Danesh

Age-related loss of CpG methylation in the tumour necrosis factor promoter.

Cytokine 2011 Dec 17;56(3):792-7. Epub 2011 Oct 17.

Department of Infection & Immunity, Medical School, University of Sheffield, Sheffield S10 2RX, United Kingdom.

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http://dx.doi.org/10.1016/j.cyto.2011.09.009DOI Listing
December 2011

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

Ann Rheum Dis 2011 Mar 10;70(3):463-8. Epub 2010 Nov 10.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Stopford Building, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1136/ard.2010.137174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033530PMC
March 2011

Treatment of rheumatoid arthritis with tumour necrosis factor inhibitors.

Br J Pharmacol 2011 Feb;162(4):785-91

Rheumatology Department, Royal Liverpool University Hospital, Liverpool, UK.

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http://dx.doi.org/10.1111/j.1476-5381.2010.01099.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042190PMC
February 2011

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.

Ann Rheum Dis 2011 Jan 30;70(1):98-103. Epub 2010 Aug 30.

NIHR-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU), University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/ard.2010.133249DOI Listing
January 2011

Alcohol consumption is inversely associated with risk and severity of rheumatoid arthritis.

Rheumatology (Oxford) 2010 Nov 28;49(11):2140-6. Epub 2010 Jul 28.

Academic Rheumatology Group, Department of Infection and Immunity, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1093/rheumatology/keq202DOI Listing
November 2010

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.

Ann Rheum Dis 2010 Jul 6;69(7):1315-20. Epub 2010 May 6.

Musculoskeletal Research Group, Institute of Cellular Medicine, University of Newcastle, 4th Floor Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1136/ard.2009.117309DOI Listing
July 2010

Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease.

Ann Rheum Dis 2010 Jun 20;69(6):1054-7. Epub 2009 Aug 20.

NIHR-Leeds Musculoskeletal Biomedical Research Unit, St James's University Hospital, Leeds Institute of Molecular Medicine, University of Leeds, Leeds LS9 7TF, UK.

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http://dx.doi.org/10.1136/ard.2009.110874DOI Listing
June 2010

Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.

Ann Rheum Dis 2010 Jun 5;69(6):1029-35. Epub 2010 May 5.

Arthritis Research Campaign Epidemiology Unit, Stopford Building, Oxford Road, University of Manchester, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1136/ard.2009.118406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930850PMC
June 2010

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

Nat Genet 2010 Jun 9;42(6):508-14. Epub 2010 May 9.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243840PMC
June 2010

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.

Ann Rheum Dis 2010 May 11;69(5):813-6. Epub 2009 May 11.

Epidemiology Unit, Faculty of Medical and Human Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1136/ard.2009.109579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009392PMC
May 2010

Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response.

Pharmacogenet Genomics 2010 May;20(5):338-41

Institute of Cellular Medicine, Musculoskeletal Research Group, Newcastle University.

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http://dx.doi.org/10.1097/FPC.0b013e32833878d7DOI Listing
May 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.

Rheumatology (Oxford) 2010 Jan 19;49(1):43-7. Epub 2009 Nov 19.

Academic Rheumatology Group, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1093/rheumatology/kep372DOI Listing
January 2010

The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality.

Crit Care Med 2009 Apr;37(4):1237-43

Section of Infection, Inflammation and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom.

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http://dx.doi.org/10.1097/CCM.0b013e31819c39bcDOI Listing
April 2009

Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis.

Arthritis Res Ther 2008 14;10(4):R80. Epub 2008 Jul 14.

Section of Musculoskeletal Sciences, School of Medicine & Biomedical Sciences, The University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK.

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http://dx.doi.org/10.1186/ar2454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575626PMC
February 2009

Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis.

Arthritis Rheum 2008 Sep;58(9):2686-93

University of Sheffield, and Royal Hallamshire Hospital, Sheffield, UK.

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http://dx.doi.org/10.1002/art.23758DOI Listing
September 2008

Epigenetic regulation of gene expression in the inflammatory response and relevance to common diseases.

Authors:
Anthony G Wilson

J Periodontol 2008 Aug;79(8 Suppl):1514-9

Academic Rheumatology Group, School of Medicine and Biomedical Sciences, University of Sheffield, Beech Hill Road, Sheffield, U.K.

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http://dx.doi.org/10.1902/jop.2008.080172DOI Listing
August 2008

The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis.

Arthritis Res Ther 2007 ;9(2):R40

Section of Musculoskeletal Sciences, School of Medicine & Biomedical Sciences, The University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2RX, UK.

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http://dx.doi.org/10.1186/ar2179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906818PMC
November 2007

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways.

J Biol Chem 2007 Jun 23;282(25):18379-87. Epub 2007 Apr 23.

Cardiovascular Research Unit and Section of Infection, Inflammation and Immunity, University of Sheffield, and Department of Histopathology, Northern General Hospital, Sheffield S10 2TN, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M610792200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366084PMC
June 2007

Cytokine gene polymorphisms involved in chronicity and complications of anterior uveitis.

Cytokine 2006 Aug 26;35(3-4):200-6. Epub 2006 Sep 26.

Department of Clinical Ophthalmology, Moorfields Eye Hospital and Institute of Ophthalmology, City Road, London EC1V 2PD, UK.

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http://dx.doi.org/10.1016/j.cyto.2006.08.003DOI Listing
August 2006

Mapping of a novel susceptibility gene for rheumatoid arthritis in the telomeric MHC region.

Cytokine 2005 Oct 30;32(2):71-5. Epub 2005 Sep 30.

Division of Genomic Medicine, The University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom.

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http://dx.doi.org/10.1016/j.cyto.2005.07.015DOI Listing
October 2005

Additional genetic susceptibility for rheumatoid arthritis telomeric of the DRB1 locus.

Arthritis Rheum 2004 Mar;50(3):763-9

The University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK.

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http://dx.doi.org/10.1002/art.20043DOI Listing
March 2004

Immunoscreening of phage-displayed cDNA-encoded polypeptides identifies B cell targets in autoimmune disease.

Biochem Biophys Res Commun 2002 Oct;298(1):169-77

Division of Clinical Sciences (North), University of Sheffield, S5 7AU, Sheffield, United Kingdom.

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http://dx.doi.org/10.1016/s0006-291x(02)02421-xDOI Listing
October 2002