Publications by authors named "Anthony E Dear"

33Publications

Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor.

Bioorg Med Chem Lett 2020 Aug 30;30(16):127291. Epub 2020 May 30.

Department of Medicine, Eastern Health Clinical School, Monash University, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2020.127291DOI Listing
August 2020

Dapagliflozin attenuates human vascular endothelial cell activation and induces vasorelaxation: A potential mechanism for inhibition of atherogenesis.

Diab Vasc Dis Res 2018 01 4;15(1):64-73. Epub 2017 Oct 4.

2 Eastern Health Clinical School and Department of Medicine, Monash University, Melbourne, VIC, Australia.

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http://journals.sagepub.com/doi/10.1177/1479164117733626
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http://dx.doi.org/10.1177/1479164117733626DOI Listing
January 2018

Epigenetic regulation of miRNA-124 and multiple downstream targets is associated with treatment response in myeloid malignancies.

Oncol Lett 2016 Sep 25;12(3):2175-2180. Epub 2016 Jul 25.

Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia; Translational Research Division, Eastern Clinical Research Unit, Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia; Department of Medicine, Eastern Health Clinical School, Monash University, Melbourne, Victoria 3128, Australia.

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https://www.spandidos-publications.com/10.3892/ol.2016.4912
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http://dx.doi.org/10.3892/ol.2016.4912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998575PMC
September 2016

Epigenetic Modulators and the New Immunotherapies.

Authors:
Anthony E Dear

N Engl J Med 2016 02;374(7):684-6

Eastern Clinical Research Unit, Translational Research Division, Department of Medicine, Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia

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http://dx.doi.org/10.1056/NEJMcibr1514673DOI Listing
February 2016

Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.

Diab Vasc Dis Res 2016 Jan 25;13(1):56-68. Epub 2015 Sep 25.

Department of Medicine, Monash University, Melbourne, VIC, Australia

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http://dx.doi.org/10.1177/1479164115605000DOI Listing
January 2016

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.

AIDS 2013 Nov;27(18):2853-62

aDepartment of Infectious Diseases, Monash University bCentre for Virology, Burnet Institute, Melbourne, Victoria cWestmead Millennium Research Institute, Westmead, New South Wales dDepartment of Biochemistry, Monash University, Clayton eInfectious Diseases Unit, Alfred Hospital, Melbourne fAustralian Centre for Blood Diseases, Department of Medicine, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1097/QAD.0000000000000067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079759PMC
November 2013

Exenatide in acute ischemic stroke.

Int J Stroke 2013 Oct;8(7):E44

Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia; Eastern Health Clinical School, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/ijs.12073DOI Listing
October 2013

Incretin based therapeutics: connections to vascular biology and implications for potential cardiovascular disease prevention: Editorial to: "Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation" by Dai et al.

Authors:
Anthony E Dear

Cardiovasc Drugs Ther 2013 Oct;27(5):363-4

Eastern Clinical Research Unit: Translational Research Division, Department of Medicine, Monash University, Level 2, 5 Arnold Street, Box Hill 3128, Melbourne, Australia,

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http://dx.doi.org/10.1007/s10557-013-6465-xDOI Listing
October 2013

GLP-1-dependent and independent effects and molecular mechanisms of a dipeptidyl peptidase 4 inhibitor in vascular endothelial cells.

Mol Biol Rep 2013 Mar 28;40(3):2273-9. Epub 2012 Nov 28.

Eastern Clinical Research Unit, Translational Research Division, Department of Medicine, Australian Centre for Blood Diseases, Monash University, 89 Commercial Rd., Prahran 3181, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/s11033-012-2290-8DOI Listing
March 2013

Clopidogrel Resistance: case reports of CYP2C19 gene variants in suspected coronary stent thrombosis.

Heart Lung Circ 2011 Oct 6;20(10):657-8. Epub 2011 Jan 6.

Department of Cardiology, Epworth Hospital, Richmond, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.hlc.2010.06.1054DOI Listing
October 2011

PPARγ-independent thiazolidinedione-mediated inhibition of NUR77 expression in vascular endothelial cells.

J Endocrinol 2011 Jan 26;208(1):R1-7. Epub 2010 Oct 26.

Australian Centre for Blood Diseases, Monash University, Prahran, Melbourne, Victoria, Australia 3181.

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http://dx.doi.org/10.1677/JOE-10-0393DOI Listing
January 2011

Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm.

Atherosclerosis 2010 Sep 6;212(1):16-29. Epub 2010 Mar 6.

Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.02.008DOI Listing
September 2010

A novel histone deacetylase inhibitor augments tamoxifen-mediated attenuation of breast carcinoma growth.

Int J Cancer 2009 Jul;125(2):483-7

Cancer Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/ijc.24350DOI Listing
July 2009

A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules.

J Endocrinol 2009 Apr 9;201(1):59-66. Epub 2009 Jan 9.

Australian Centre for Blood Diseases, Monash University, Prahran, Melbourne, Victoria.

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http://dx.doi.org/10.1677/JOE-08-0468DOI Listing
April 2009

Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin.

Mol Cancer Ther 2008 May;7(5):1066-79

Cancer Immunology Program, Peter MacCallum Cancer Centre, Trescowthick Research Laboratories, St. Andrews Place, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2256DOI Listing
May 2008

Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions.

Eur Heart J 2008 Mar 9;29(5):665-72. Epub 2008 Feb 9.

Vascular Biology Unit, Department of Surgery, School of Medicine, James Cook University, Townsville, QLD 4811, Australia.

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http://dx.doi.org/10.1093/eurheartj/ehm557DOI Listing
March 2008

Glucagon-like peptide-1 attenuates tumour necrosis factor-alpha-mediated induction of plasminogen [corrected] activator inhibitor-1 expression.

J Endocrinol 2008 Jan;196(1):57-65

Australian Centre for Blood Diseases, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1677/JOE-07-0387DOI Listing
January 2008

A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.

J Vasc Res 2008 24;45(2):143-52. Epub 2007 Oct 24.

Department of Pharmacology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1159/000110041DOI Listing
March 2008

Genotype and adverse drug reactions to warfarin.

Med J Aust 2007 Jul;187(1):61-2

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July 2007

Association between osteopontin and human abdominal aortic aneurysm.

Arterioscler Thromb Vasc Biol 2007 Mar 14;27(3):655-60. Epub 2006 Dec 14.

The Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland, 4811 Australia.

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http://dx.doi.org/10.1161/01.ATV.0000255560.49503.4eDOI Listing
March 2007

Conformational analogues of Oxamflatin as histone deacetylase inhibitors.

Org Biomol Chem 2006 Oct 31;4(20):3778-84. Epub 2006 Aug 31.

Australian Centre for Blood Diseases, Department of Medicine, Monash University, 6th floor Barnet Tower, 89 Commercial Rd, Prahran 3181, Australia.

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http://dx.doi.org/10.1039/b608213kDOI Listing
October 2006

Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis.

Med J Aust 2005 Apr;182(7):365-6; author reply 367-8

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April 2005

Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Cancer Res 2003 Aug;63(15):4460-71

Cancer Immunology Program, The Peter MacCallum Cancer Institute, East Melbourne 3002, Victoria, Australia.

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http://cancerres.aacrjournals.org/content/63/15/4460.full.pd
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August 2003

Homocysteine: an aetiological contributor to peripheral vascular arterial disease.

ANZ J Surg 2002 Sep;72(9):668-71

Department of Surgery, Monash University, Box Hill Hospital, Australia.

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http://dx.doi.org/10.1046/j.1445-2197.2002.02509.xDOI Listing
September 2002