Anthony DeFranco

Anthony DeFranco

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Anthony DeFranco

Anthony DeFranco

Publications by authors named "Anthony DeFranco"

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Antigen Complexed with a TLR9 Agonist Bolsters c-Myc and mTORC1 Activity in Germinal Center B Lymphocytes.

Immunohorizons 2019 Aug 19;3(8):389-401. Epub 2019 Aug 19.

Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143; and

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http://dx.doi.org/10.4049/immunohorizons.1900030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738343PMC
August 2019

Multilayer Control of B Cell Activation by the B Cell Antigen Receptor: Following Themes Initiated With Bill Paul.

Front Immunol 2018 23;9:739. Epub 2018 Apr 23.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925841PMC
June 2019

Understanding the Musical Dance of the Engaged Coronary Catheter: Insights From Advanced Myocardial Mechanics.

J Invasive Cardiol 2018 09;30(9):E97-E98

Aurora Cardiovascular Services, Aurora St. Luke's Medical Center, 2801 W. Kinnickinnic River Parkway, Ste. 840, Milwaukee, WI 53215 USA.

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September 2018

B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle.

J Immunol 2018 02 27;200(3):937-948. Epub 2017 Dec 27.

Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;

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http://dx.doi.org/10.4049/jimmunol.1701067DOI Listing
February 2018

Innate B cells cleave to the marginal zone.

Nat Immunol 2017 02;18(3):248-250

Department of Microbiology &Immunology, University of California-San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/ni.3685DOI Listing
February 2017

Germinal centers and autoimmune disease in humans and mice.

Immunol Cell Biol 2016 11 26;94(10):918-924. Epub 2016 Aug 26.

Department of Microbiology and Immunology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/icb.2016.78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663225PMC
November 2016

MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase.

PLoS Pathog 2016 08 19;12(8):e1005787. Epub 2016 Aug 19.

Departments of Pediatrics, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991787PMC
August 2016

The germinal center antibody response in health and disease.

F1000Res 2016 25;5. Epub 2016 May 25.

University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.12688/f1000research.7717.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882753PMC
June 2016

Splenic red pulp macrophages produce type I interferons as early sentinels of malaria infection but are dispensable for control.

PLoS One 2012 29;7(10):e48126. Epub 2012 Oct 29.

Division of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048126PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483282PMC
August 2014

Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses.

Proc Natl Acad Sci U S A 2014 Aug 22;111(31):E3224-33. Epub 2014 Jul 22.

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143

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http://dx.doi.org/10.1073/pnas.1323985111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128120PMC
August 2014

Left ventricular apical aneurysm: a novel phenotype of Fabry's disease.

Eur Heart J Cardiovasc Imaging 2014 May 5;15(5):585. Epub 2013 Nov 5.

Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health, 2801 W. Kinnickinnic River Parkway, #840, Milwaukee, WI 53215, USA.

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http://dx.doi.org/10.1093/ehjci/jet197DOI Listing
May 2014

Impact of prior admissions on 30-day readmissions in medicare heart failure inpatients.

Mayo Clin Proc 2014 May 29;89(5):623-30. Epub 2014 Mar 29.

Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1016/j.mayocp.2013.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017659PMC
May 2014

B cell-specific loss of Lyn kinase leads to autoimmunity.

J Immunol 2014 Feb 27;192(3):919-28. Epub 2013 Dec 27.

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143.

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http://dx.doi.org/10.4049/jimmunol.1301979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900234PMC
February 2014

Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses.

Sci Signal 2013 Oct 15;6(297):ra91. Epub 2013 Oct 15.

1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/scisignal.2004189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108475PMC
October 2013

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

J Immunol 2012 Nov 28;189(9):4405-16. Epub 2012 Sep 28.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.4049/jimmunol.1201433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515638PMC
November 2012

Contribution of Toll-like receptor signaling to germinal center antibody responses.

Immunol Rev 2012 May;247(1):64-72

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143-0414, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2012.01115.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334874PMC
May 2012

Lyn deficiency affects B-cell maturation as well as survival.

Eur J Immunol 2012 Feb 14;42(2):511-21. Epub 2011 Dec 14.

The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat-Gan, Israel.

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http://dx.doi.org/10.1002/eji.201141940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516919PMC
February 2012

Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.

Eur J Immunol 2011 Dec 10;41(12):3645-55. Epub 2011 Nov 10.

Division of Rheumatology, Department of Medicine, University of California, San Francisco, CA 94143-0414, USA.

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http://dx.doi.org/10.1002/eji.201141708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517141PMC
December 2011

B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice.

Proc Natl Acad Sci U S A 2011 Oct 12;108(41):E823-32. Epub 2011 Sep 12.

Department of Laboratory Medicine and Microbiology/Immunology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.1107913108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193193PMC
October 2011

Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors.

Proc Natl Acad Sci U S A 2011 Jan 20;108(1):278-83. Epub 2010 Dec 20.

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.1011549108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017180PMC
January 2011

Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.

J Exp Med 2010 Aug 12;207(8):1757-73. Epub 2010 Jul 12.

Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1084/jem.20100086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916124PMC
August 2010

Recommendation of low-salt diet and short-term outcomes in heart failure with preserved systolic function.

Am J Med 2009 Nov;122(11):1029-36

Division of Cardiovascular Medicine, University of Michigan Department of Internal Medicine, 1500 East Medical Center Drive, SPC 5853, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.amjmed.2009.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769220PMC
November 2009

"Dangerous crystals".

Immunity 2008 Nov;29(5):670-1

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.immuni.2008.10.005DOI Listing
November 2008

Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms.

Immunity 2008 Aug 24;29(2):272-82. Epub 2008 Jul 24.

Department of Microbiology & Immunology, University of California, San Francisco, CA, 94143, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130800315
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2008.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847796PMC
August 2008

Lipid rafts and B cell signaling.

Semin Cell Dev Biol 2007 Oct 24;18(5):616-26. Epub 2007 Jul 24.

Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA 94143, United States.

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http://dx.doi.org/10.1016/j.semcdb.2007.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169358PMC
October 2007

Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics.

Nat Immunol 2006 Jun 30;7(6):625-33. Epub 2006 Apr 30.

Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ni1337DOI Listing
June 2006

TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements.

J Biol Chem 2005 Nov 16;280(44):37107-17. Epub 2005 Aug 16.

Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1074/jbc.M504951200DOI Listing
November 2005

Bcl10 can promote survival of antigen-stimulated B lymphocytes.

Blood 2005 Sep 5;106(6):2105-12. Epub 2005 May 5.

Department of Microbiology and Immunology, UCSF, 513 Parnassus Ave, San Francisco, CA 94143-0414, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-04-12
Publisher Site
http://dx.doi.org/10.1182/blood-2004-04-1248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895143PMC
September 2005

Taking the ACC/AHA guidelines for care of Acute Myocardial Infarction to the bedside: the GAP projects in southeastern Michigan.

Am Heart J 2004 Nov;148(5 Suppl):S49-51

University of Michigan Health System, Ann Arbor, Mich 48109-0366, USA.

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http://dx.doi.org/10.1016/j.ahj.2004.09.016DOI Listing
November 2004

Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors.

J Biol Chem 2004 Apr 19;279(18):19008-17. Epub 2004 Feb 19.

George Williams Hooper Foundation, University of California, Sa Francisco, 94143-0414, USA.

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http://dx.doi.org/10.1074/jbc.M311618200DOI Listing
April 2004

Signaling mutations and autoimmunity.

Curr Dir Autoimmun 2003 ;6:61-88

George Williams Hooper Foundation, Department of Microbiology and Immunology, University of California, San Francisco, Calif., USA.

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May 2003

Visualizing lipid raft dynamics and early signaling events during antigen receptor-mediated B-lymphocyte activation.

Mol Biol Cell 2003 Feb;14(2):432-44

Department of Microbiology and Immunology, G. W. Hooper Foundation, University of California, San Francisco, 94143, USA.

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http://dx.doi.org/10.1091/mbc.02-05-0078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149983PMC
February 2003

Making and breaking tolerance.

Curr Opin Immunol 2002 Dec;14(6):744-59

University Health Network, Ontario Cancer Institute, Toronto, Canada.

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http://dx.doi.org/10.1016/s0952-7915(02)00406-5DOI Listing
December 2002