Anthony Chubb

Anthony Chubb

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Anthony Chubb

Anthony Chubb

Publications by authors named "Anthony Chubb"

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion.

PLoS One 2015 3;10(6):e0127383. Epub 2015 Jun 3.

Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland; Complex and Adaptive Systems Laboratory, University College Dublin, Dublin, Ireland; School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127383PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454681PMC
May 2016

Two crystal structures of the FK506-binding domain of Plasmodium falciparum FKBP35 in complex with rapamycin at high resolution.

Acta Crystallogr D Biol Crystallogr 2015 Jun 14;71(Pt 6):1319-27. Epub 2015 May 14.

Centre de Biochimie Structurale, CNRS UMR5048, INSERM U1054, Université de Montpellier, Montpellier, France.

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http://dx.doi.org/10.1107/S1399004715006239DOI Listing
June 2015

A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity.

J Inorg Biochem 2013 Jul 29;124:70-7. Epub 2013 Mar 29.

Centre for Synthesis and Chemical Biology, Department of Pharmaceutical and Medicinal Chemistry, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin 2, Ireland.

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http://linkinghub.elsevier.com/retrieve/pii/S016201341300069
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http://dx.doi.org/10.1016/j.jinorgbio.2013.03.011DOI Listing
July 2013

TIN-a combinatorial compound collection of synthetically feasible multicomponent synthesis products.

J Chem Inf Model 2011 May 15;51(5):986-95. Epub 2011 Apr 15.

Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland , 123 St. Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/ci100443xDOI Listing
May 2011

CycloPs: generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids.

J Chem Inf Model 2011 Apr 24;51(4):829-36. Epub 2011 Mar 24.

UCD Complex and Applied Systems Laboratory, Conway Institute of Biomolecular and Biomedical Sciences, and School of Medicine and Medical Sciences, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1021/ci100431rDOI Listing
April 2011

Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activity.

Bioorg Med Chem Lett 2009 Aug 13;19(15):4213-6. Epub 2009 Jun 13.

Centre for Synthesis and Chemical Biology, Department of Pharmaceutical and Medicinal Chemistry, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1016/j.bmcl.2009.05.120DOI Listing
August 2009

Genomes2Drugs: identifies target proteins and lead drugs from proteome data.

PLoS One 2009 Jul 10;4(7):e6195. Epub 2009 Jul 10.

Molecular Modelling Group, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006195PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704375PMC
July 2009

RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin alpha(IIb)beta3.

Biochem Biophys Res Commun 2008 May 10;369(4):1088-93. Epub 2008 Mar 10.

Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1016/j.bbrc.2008.02.142DOI Listing
May 2008

Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties.

Biol Chem 2006 Aug;387(8):1043-51

Division of Medical Biochemistry and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1515/BC.2006.129DOI Listing
August 2006

The productive conformation of prostaglandin G2 at the peroxidase site of prostaglandin endoperoxide H synthase: docking, molecular dynamics, and site-directed mutagenesis studies.

Biochemistry 2006 Jan;45(3):811-20

Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/bi051973kDOI Listing
January 2006

Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity.

Org Biomol Chem 2005 Oct 8;3(20):3678-85. Epub 2005 Sep 8.

Centre for Synthesis and Chemical Biology, Department of Pharmaceutical and Medicinal Chemistry, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1039/b505525cDOI Listing
October 2005

Deletion of the cytoplasmic domain increases basal shedding of angiotensin-converting enzyme.

Biochem Biophys Res Commun 2004 Feb;314(4):971-5

Division of Medical Biochemistry, University of Cape Town Medical School, Observatory 7925, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.bbrc.2003.12.198DOI Listing
February 2004

Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain.

Biochem Biophys Res Commun 2002 Oct;297(5):1225-30

Division of Medical Biochemistry, University of Cape Town Medical School, Observatory 7925, Cape Town, South Africa.

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http://dx.doi.org/10.1016/s0006-291x(02)02324-0DOI Listing
October 2002