Publications

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.
Nat Commun 2017 May 9;8:15142. Epub 2017 May 9.
Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.




T cell immune deficiency in zap70 mutant zebrafish.
Mol Cell Biol 2016 Sep 6. Epub 2016 Sep 6.
Molecular Pathology, Massachusetts General Hospital, Charlestown, MA, USA Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA Cancer Center, Massachusetts General Hospital, Charlestown, MA, USA Harvard Stem Cell Institute, Cambridge MA, USA

Recurrent hemizygous deletions in cancers may optimize proliferative potential.
Science 2012 Jul 24;337(6090):104-9. Epub 2012 May 24.
Department of Genetics, Harvard University Medical School, and Division of Genetics, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.

Sox2 Suppresses Gastric Tumorigenesis in Mice.
Cell Rep 2016 08 4;16(7):1929-41. Epub 2016 Aug 4.
Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Howard Hughes Medical Institute and Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Harvard University, Cambridge, MA 02138, USA. Electronic address:

Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.
Genes Dev 2016 12;30(24):2684-2695
Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.


Genetic Intersection of Tsix and Hedgehog Signaling during the Initiation of X-Chromosome Inactivation.
Dev Cell 2017 11 26;43(3):359-371.e6. Epub 2017 Oct 26.
Howard Hughes Medical Institute, Boston, MA 02114, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

OF