Publications by authors named "Annie Yarwood"

18Publications

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.

Authors:
Elena López-Isac Samantha L Smith Miranda C Marion Abigail Wood Marc Sudman Annie Yarwood Chenfu Shi Vasanthi Priyadarshini Gaddi Paul Martin Sampath Prahalad Stephen Eyre Gisela Orozco Andrew P Morris Carl D Langefeld Susan D Thompson Wendy Thomson John Bowes

Ann Rheum Dis 2020 Oct 26. Epub 2020 Oct 26.

Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK

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October 2020

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31.

Authors:
Helen Ray-Jones Kate Duffus Amanda McGovern Paul Martin Chenfu Shi Jenny Hankinson Oliver Gough Annie Yarwood Andrew P Morris Antony Adamson Christopher Taylor James Ding Vasanthi Priyadarshini Gaddi Yao Fu Patrick Gaffney Gisela Orozco Richard B Warren Steve Eyre

BMC Biol 2020 05 4;18(1):47. Epub 2020 May 4.

Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

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May 2020

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing.

Authors:
Samantha L Smith Philippa R Kennedy Kevin B Stacey Jonathan D Worboys Annie Yarwood Seungmae Seo Everardo Hegewisch Solloa Brandon Mistretta Sujash S Chatterjee Preethi Gunaratne Kimaada Allette Ying-Chih Wang Melissa Laird Smith Robert Sebra Emily M Mace Amir Horowitz Wendy Thomson Paul Martin Steve Eyre Daniel M Davis

Blood Adv 2020 04;4(7):1388-1406

The Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, and.

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April 2020

Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases.

Authors:
Paul Martin James Ding Kate Duffus Vasanthi Priyadarshini Gaddi Amanda McGovern Helen Ray-Jones Annie Yarwood Jane Worthington Anne Barton Gisela Orozco

Ann Rheum Dis 2019 08 15;78(8):1127-1134. Epub 2019 May 15.

Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK

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August 2019

Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis.

Authors:
Anne Hinks Miranda C Marion Joanna Cobb Mary E Comeau Marc Sudman Hannah C Ainsworth John Bowes Mara L Becker John F Bohnsack Johannes-Peter Haas Daniel J Lovell Elizabeth D Mellins J Lee Nelson Ellen Nordal Marilynn Punaro Ann M Reed Carlos D Rose Alan M Rosenberg Marite Rygg Samantha L Smith Anne M Stevens Vibeke Videm Carol A Wallace Lucy R Wedderburn Annie Yarwood Rae S M Yeung Carl D Langefeld Susan D Thompson Wendy Thomson Sampath Prahalad

Arthritis Rheumatol 2018 06 21;70(6):957-962. Epub 2018 Apr 21.

Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.

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June 2018

Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.

Authors:
Paul Martin Amanda McGovern Jonathan Massey Stefan Schoenfelder Kate Duffus Annie Yarwood Anne Barton Jane Worthington Peter Fraser Stephen Eyre Gisela Orozco

PLoS One 2016 18;11(11):e0166923. Epub 2016 Nov 18.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Siences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, United Kingdom.

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June 2017

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

Authors:
Amanda McGovern Stefan Schoenfelder Paul Martin Jonathan Massey Kate Duffus Darren Plant Annie Yarwood Arthur G Pratt Amy E Anderson John D Isaacs Julie Diboll Nishanthi Thalayasingam Caroline Ospelt Anne Barton Jane Worthington Peter Fraser Stephen Eyre Gisela Orozco

Genome Biol 2016 11 1;17(1):212. Epub 2016 Nov 1.

Arthritis Research UK Centre for Genetics and Genomics, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, UK.

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November 2016

Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery.

Authors:
Annie Yarwood Steve Eyre Jane Worthington

Expert Opin Drug Discov 2016 Aug 7;11(8):805-13. Epub 2016 Jun 7.

a Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre , The University of Manchester , Manchester , UK.

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August 2016

Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis.

Authors:
Wen-Hua Wei John Bowes Darren Plant Sebastien Viatte Annie Yarwood Jonathan Massey Jane Worthington Stephen Eyre

Sci Rep 2016 04 25;6:25014. Epub 2016 Apr 25.

Arthritis Research UK Centre for Genetics and Genomics, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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April 2016

Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples.

Authors:
Samantha Louise Smith Stephen Eyre Annie Yarwood Kimme Hyrich Ann W Morgan A G Wilson John Isaacs Darren Plant Anne Barton

Arthritis Res Ther 2015 Dec 14;17:359. Epub 2015 Dec 14.

Arthritis Research UK, Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Sciences Centre, the University of Manchester, Manchester, UK.

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December 2015

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.

Authors:
Paul Martin Amanda McGovern Gisela Orozco Kate Duffus Annie Yarwood Stefan Schoenfelder Nicholas J Cooper Anne Barton Chris Wallace Peter Fraser Jane Worthington Steve Eyre

Nat Commun 2015 Nov 30;6:10069. Epub 2015 Nov 30.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, The University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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November 2015

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.

Authors:
Annie Yarwood Sebastien Viatte Yukinori Okada Robert Plenge Kazuhiko Yamamoto Anne Barton Deborah Symmons Soumya Raychaudhuri Lars Klareskog Peter Gregersen Jane Worthington Steve Eyre

Ann Rheum Dis 2016 Jan 17;75(1):317-20. Epub 2015 Sep 17.

Faculty of Medical and Human Sciences, Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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January 2016

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

Authors:
Sebastien Viatte Darren Plant Buhm Han Bo Fu Annie Yarwood Wendy Thomson Deborah P M Symmons Jane Worthington Adam Young Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Soumya Raychaudhuri Anne Barton

JAMA 2015 Apr;313(16):1645-56

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, England2NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manches.

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April 2015

The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.

Authors:
Annie Yarwood Tom W J Huizinga Jane Worthington

Rheumatology (Oxford) 2016 Feb 18;55(2):199-209. Epub 2014 Sep 18.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, Stopford Building, University of Manchester, Manchester, UK, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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February 2016

The role of genetic polymorphisms regulating vitamin D levels in rheumatoid arthritis outcome: a Mendelian randomisation approach.

Authors:
Sebastien Viatte Annie Yarwood Kate McAllister Shibeb Al-Mudhaffer Bo Fu Edward Flynn Deborah P M Symmons Adam Young Anne Barton

Ann Rheum Dis 2014 Jul 20;73(7):1430-3. Epub 2014 Mar 20.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK.

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July 2014

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach.

Authors:
Annie Yarwood Sebastien Viatte Darren Plant Ann W Morgan John Isaacs Anthony G Wilson Kimme Hyrich Steve Eyre Anne Barton

Ann Rheum Dis 2014 May 9;73(5):938-40. Epub 2013 Dec 9.

Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, , Manchester, UK.

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May 2014

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.

Authors:
Annie Yarwood Buhm Han Soumya Raychaudhuri John Bowes Mark Lunt Dimitrios A Pappas Joel Kremer Jeffrey D Greenberg Robert Plenge Jane Worthington Anne Barton Steve Eyre

Ann Rheum Dis 2015 Jan 3;74(1):170-6. Epub 2013 Oct 3.

Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK.

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January 2015

Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.

Authors:
Kate McAllister Annie Yarwood John Bowes Gisela Orozco Sebastian Viatte Dorothée Diogo Lynne J Hocking Sophia Steer Paul Wordsworth A G Wilson Ann W Morgan Joel M Kremer Dimitrios Pappas Peter Gregersen Lars Klareskog Robert Plenge Anne Barton Jeffrey Greenberg Jane Worthington Stephen Eyre

Arthritis Rheum 2013 Dec;65(12):3058-62

University of Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, and Manchester Academic Health Science Centre, Manchester, UK.

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December 2013