Publications by authors named "Annette T Byrne"

42Publications

Precision Therapy in RAS Mutant Colorectal Cancer.

Gastroenterology 2020 03 21;158(4):806-811. Epub 2020 Jan 21.

Royal College of Surgeons in Ireland, Dept of Physiology and Medical Physics, RCSI Centre for Systems Medicine, Dublin 2, Ireland.

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http://dx.doi.org/10.1053/j.gastro.2019.12.051DOI Listing
March 2020

Therapeutic Targeting of the Colorectal Tumor Stroma.

Gastroenterology 2020 01 14;158(2):303-321. Epub 2019 Oct 14.

Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1053/j.gastro.2019.09.045DOI Listing
January 2020

Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents.

Sci Rep 2019 06 24;9(1):9204. Epub 2019 Jun 24.

Department of Physiology and Medical Physics, Centre for Systems Medicine, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/s41598-019-45444-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591410PMC
June 2019

RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells.

Drug Deliv Transl Res 2019 06;9(3):679-693

Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s13346-019-00637-yDOI Listing
June 2019

Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate.

Proteomics Clin Appl 2019 07 19;13(4):e1800159. Epub 2019 Mar 19.

RCSI Centre for Systems Medicine, Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, D02 HX03, Ireland.

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http://dx.doi.org/10.1002/prca.201800159DOI Listing
July 2019

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

J Clin Oncol 2018 07 24;36(20):2052-2060. Epub 2018 May 24.

Erik van Dijk, Hedde D. Biesma, Martijn Cordes, Maarten Neerincx, Paul P. Eijk, Henk M.W. Verheul, Nicole C.T. van Grieken, and Bauke Ylstra, Vrije Universiteit Medical Center; Gerrit A. Meijer, Netherlands Cancer Institute; Cornelis J.A. Punt, Academic Medical Center, Amsterdam; Miriam Koopman, University Medical Center Utrecht, Utrecht, the Netherlands; Dominiek Smeets and Diether Lambrechts, KU Leuven, Leuven, Belgium; Sudipto Das, Orna Bacon, Jochen H.M. Prehn, Bryan T. Hennessey, Darran P. O'Connor, and Annette T. Byrne, Royal College of Surgeons in Ireland; Verena Murphy, Cancer Trials Ireland; Anna Barat, Deborah A. McNamara, and Elaine W. Kay, Beaumont Hospital; Bozena Fender and William M. Gallagher, OncoMark Ltd; Rut Klinger and William M. Gallagher, University College Dublin, Dublin, United Kingdom; Johannes Betge, Timo Gaiser, and Matthias P.A. Ebert, University Hospital Mannheim, Mannheim, Germany; and Fotios Loupakis, Veneto Institute of Oncology IOV-IRCCS Padua, Italy.

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http://dx.doi.org/10.1200/JCO.2017.77.1782DOI Listing
July 2018

The IL-17-Th1/Th17 pathway: an attractive target for lung cancer therapy?

Expert Opin Ther Targets 2016 11 11;20(11):1339-1356. Epub 2016 Jul 11.

e Thoracic Oncology Research Group , IMM, St James's Hospital , Dublin , Ireland.

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http://dx.doi.org/10.1080/14728222.2016.1206891DOI Listing
November 2016

Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements.

J Theor Biol 2016 08 5;402:129-43. Epub 2016 May 5.

Department of Cardiovascular Sciences, KU Leuven, Herestraat 49, Box 911, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2016.04.028DOI Listing
August 2016

Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer.

Eur J Pharmacol 2016 Jun 17;780:53-64. Epub 2016 Mar 17.

Centre for Systems Medicine and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2016.03.031DOI Listing
June 2016

Integrating Colon Cancer Microarray Data: Associating Locus-Specific Methylation Groups to Gene Expression-Based Classifications.

Microarrays (Basel) 2015 Nov 23;4(4):630-46. Epub 2015 Nov 23.

Centre for Systems Medicine and Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 Saint Stephen's Green, Dublin 2, D02 YN77 Ireland.

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http://dx.doi.org/10.3390/microarrays4040630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996409PMC
November 2015

Comparison of performance in a four year graduate entry medical programme and a traditional five/six year programme.

BMC Med Educ 2014 Dec 10;14:248. Epub 2014 Dec 10.

Royal College of Surgeons in Ireland, Graduate Entry Programme, Reservoir House, Ballymoss Road, Dublin, 18, Ireland.

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http://dx.doi.org/10.1186/s12909-014-0248-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267744PMC
December 2014

Validation of an imageable surgical resection animal model of Glioblastoma (GBM).

J Neurosci Methods 2014 Aug 18;233:99-104. Epub 2014 Jun 18.

Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jneumeth.2014.05.006DOI Listing
August 2014

Comparison of anthropometric-based equations for estimation of body fat percentage in a normal-weight and overweight female cohort: validation via air-displacement plethysmography.

Public Health Nutr 2015 Feb 16;18(3):446-52. Epub 2014 Apr 16.

5Department of Physiology and Medical Physics,Royal College of Surgeons in Ireland,123 St Stephens Green,Dublin 2,Republic of Ireland.

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http://www.journals.cambridge.org/abstract_S1368980014000597
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http://dx.doi.org/10.1017/S1368980014000597DOI Listing
February 2015

Molecular imaging in the development of a novel treatment paradigm for glioblastoma (GBM): an integrated multidisciplinary commentary.

Drug Discov Today 2013 Nov 20;18(21-22):1052-66. Epub 2013 Jun 20.

Department of Physiology and Medical Physics & Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.drudis.2013.06.004DOI Listing
November 2013

In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme.

Mol Imaging 2013 May;12(3):161-72

Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.

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May 2013

The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate.

Biomaterials 2013 Apr 21;34(11):2710-8. Epub 2013 Jan 21.

School of Biomolecular and Biomedical Sciences and Centre for Synthesis and Chemical Biology, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.biomaterials.2012.12.032DOI Listing
April 2013

Mechanism of cell death mediated by a BF2-chelated tetraaryl-azadipyrromethene photodynamic therapeutic: dissection of the apoptotic pathway in vitro and in vivo.

Int J Cancer 2012 Feb 26;130(3):705-15. Epub 2011 May 26.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1002/ijc.26073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568043PMC
February 2012

The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy.

Drug Discov Today 2011 Mar 22;16(5-6):219-28. Epub 2011 Jan 22.

Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.drudis.2011.01.005DOI Listing
March 2011

Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells.

Invest New Drugs 2011 Oct 16;29(5):752-9. Epub 2010 Mar 16.

National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.

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http://dx.doi.org/10.1007/s10637-010-9415-5DOI Listing
October 2011

Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells.

Invest New Drugs 2011 Oct 16;29(5):752-9. Epub 2010 Mar 16.

National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.

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http://dx.doi.org/10.1007/s10637-010-9415-5DOI Listing
October 2011

Recent advances in molecular imaging biomarkers in cancer: application of bench to bedside technologies.

Drug Discov Today 2010 Feb 24;15(3-4):102-14. Epub 2009 Dec 24.

Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.drudis.2009.12.003DOI Listing
February 2010

Bioluminescent imaging: a critical tool in pre-clinical oncology research.

J Pathol 2010 Feb;220(3):317-27

UCD School of Medicine and Medical Science, Health Science Building, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1002/path.2656DOI Listing
February 2010

Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy.

Photochem Photobiol 2009 Sep-Oct;85(5):1053-74. Epub 2009 Aug 3.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1111/j.1751-1097.2009.00585.xDOI Listing
December 2009