Annette Schenck

Annette Schenck

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Annette Schenck

Annette Schenck

Publications by authors named "Annette Schenck"

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Habituation Learning Is a Widely Affected Mechanism in Drosophila Models of Intellectual Disability and Autism Spectrum Disorders.

Biol Psychiatry 2019 Aug 9;86(4):294-305. Epub 2019 May 9.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.04.029DOI Listing
August 2019

Integrative network and brain expression analysis reveals mechanistic modules in ataxia.

J Med Genet 2019 May 27;56(5):283-292. Epub 2018 Dec 27.

Department of Human Genetics, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1136/jmedgenet-2018-105703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581079PMC
May 2019

Intellectual disability and autism spectrum disorders 'on the fly': insights from .

Dis Model Mech 2019 05 13;12(5). Epub 2019 May 13.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands

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http://dx.doi.org/10.1242/dmm.039180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550041PMC
May 2019

The histone methyltransferase G9a regulates tolerance to oxidative stress-induced energy consumption.

PLoS Biol 2019 03 12;17(3):e2006146. Epub 2019 Mar 12.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.pbio.2006146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413895PMC
March 2019

A Mitochondrial Complex I Deficiency Phenotype Array.

Front Genet 2019 27;10:245. Epub 2019 Mar 27.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, Netherlands.

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https://www.frontiersin.org/article/10.3389/fgene.2019.00245
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http://dx.doi.org/10.3389/fgene.2019.00245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445954PMC
March 2019

Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila.

Sci Rep 2019 Feb 14;9(1):2065. Epub 2019 Feb 14.

Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-38559-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375949PMC
February 2019

SnapShot: Biology of Genetic Ataxias.

Cell 2018 10;175(3):890-890.e1

Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2018.10.017DOI Listing
October 2018

GDAP2 mutations implicate susceptibility to cellular stress in a new form of cerebellar ataxia.

Brain 2018 09;141(9):2592-2604

Department of Neurology, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Centre, GC Nijmegen, The Netherlands.

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https://academic.oup.com/brain/advance-article/doi/10.1093/b
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http://dx.doi.org/10.1093/brain/awy198DOI Listing
September 2018

Feeding difficulties, a key feature of the NDUFS4 mitochondrial disease model.

Dis Model Mech 2018 03 27;11(3). Epub 2018 Mar 27.

Khondrion BV, Philips van Leydenlaan 15, 6525 EX, Nijmegen, The Netherlands

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http://dx.doi.org/10.1242/dmm.032482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897729PMC
March 2018

High-throughput Analysis of Locomotor Behavior in the Drosophila Island Assay.

J Vis Exp 2017 11 5(129). Epub 2017 Nov 5.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center;

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http://dx.doi.org/10.3791/55892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755321PMC
November 2017

Drosophila Courtship Conditioning As a Measure of Learning and Memory.

J Vis Exp 2017 06 5(124). Epub 2017 Jun 5.

Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University; Department of Biology, Faculty of Science, Western University;

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http://dx.doi.org/10.3791/55808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608251PMC
June 2017

A New Fiji-Based Algorithm That Systematically Quantifies Nine Synaptic Parameters Provides Insights into Drosophila NMJ Morphometry.

PLoS Comput Biol 2016 Mar 21;12(3):e1004823. Epub 2016 Mar 21.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.pcbi.1004823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801422PMC
March 2016

Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules.

Am J Hum Genet 2016 Jan;98(1):149-64

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, 6525 GA Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716705PMC
January 2016

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

Hum Mol Genet 2015 Dec 16;24(23):6736-55. Epub 2015 Sep 16.

Institut Clinique de la Souris, PHENOMIN, GIE CERBM, 1 rue Laurent Fries, 67404 Illkirch, France, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France, Centre National de la Recherche Scientifique, UMR7104, Illkirch, France, Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France and Université de Strasbourg, Illkirch, France

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http://dx.doi.org/10.1093/hmg/ddv380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634377PMC
December 2015

Converging evidence does not support GIT1 as an ADHD risk gene.

Am J Med Genet B Neuropsychiatr Genet 2015 Sep 10;168(6):492-507. Epub 2015 Jun 10.

Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.b.32327DOI Listing
September 2015

Mitochondrial diseases: Drosophila melanogaster as a model to evaluate potential therapeutics.

Int J Biochem Cell Biol 2015 Jun 7;63:60-5. Epub 2015 Feb 7.

Khondrion BV, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13572725150003
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http://dx.doi.org/10.1016/j.biocel.2015.01.024DOI Listing
June 2015

The epigenetic regulator G9a mediates tolerance to RNA virus infection in Drosophila.

PLoS Pathog 2015 Apr 16;11(4):e1004692. Epub 2015 Apr 16.

Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1004692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399909PMC
April 2015

Altered GPM6A/M6 dosage impairs cognition and causes phenotypes responsive to cholesterol in human and Drosophila.

Hum Mutat 2014 Dec;35(12):1495-505

Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/humu.22697DOI Listing
December 2014

Drosophila models of early onset cognitive disorders and their clinical applications.

Neurosci Biobehav Rev 2014 Oct 21;46 Pt 2:326-42. Epub 2014 Mar 21.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2014.01.013DOI Listing
October 2014

Genome sequencing identifies major causes of severe intellectual disability.

Nature 2014 Jul 4;511(7509):344-7. Epub 2014 Jun 4.

1] Department of Human Genetics, Radboud Institute for Molecular Life Sciences and Donders Centre for Neuroscience, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, the Netherlands [2] Department of Clinical Genetics, Maastricht University Medical Centre. Universiteitssingel 50, 6229 ER Maastricht, the Netherlands [3].

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http://dx.doi.org/10.1038/nature13394DOI Listing
July 2014

The genetics of cognitive epigenetics.

Neuropharmacology 2014 May 13;80:83-94. Epub 2014 Jan 13.

Radboud University Medical Center, Department of Human Genetics, Nijmegen Center for Molecular Life Sciences (NCMLS), Nijmegen, The Netherlands; Radboud University Medical Center, Department of Cognitive Neurosciences, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2013.12.025DOI Listing
May 2014

Human intellectual disability genes form conserved functional modules in Drosophila.

PLoS Genet 2013 Oct 31;9(10):e1003911. Epub 2013 Oct 31.

Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1003911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814316PMC
October 2013

Analysis of adhesion molecules and basement membrane contributions to synaptic adhesion at the Drosophila embryonic NMJ.

PLoS One 2012 30;7(4):e36339. Epub 2012 Apr 30.

Faculty of Life Sciences, Wellcome Trust Centre for Cell-Matrix Research, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036339PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340374PMC
September 2012

CYFIP dependent actin remodeling controls specific aspects of Drosophila eye morphogenesis.

Dev Biol 2011 Nov 22;359(1):37-46. Epub 2011 Aug 22.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/UDS, BP 10142, 67404 Illkirch, CU de Strasbourg, France. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2011.08.009DOI Listing
November 2011

Epigenetic regulation of learning and memory by Drosophila EHMT/G9a.

PLoS Biol 2011 Jan 4;9(1):e1000569. Epub 2011 Jan 4.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.pbio.1000569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014924PMC
January 2011

HSPC300 and its role in neuronal connectivity.

Neural Dev 2007 Sep 25;2:18. Epub 2007 Sep 25.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP 10142, 67404 Illkirch, CU de Strasbourg, France.

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http://neuraldevelopment.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1749-8104-2-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098765PMC
September 2007

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.

Nature 2006 Aug 16;442(7104):814-7. Epub 2006 Jul 16.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

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http://www.nature.com/doifinder/10.1038/nature04976
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http://dx.doi.org/10.1038/nature04976DOI Listing
August 2006

FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.

Hum Mol Genet 2005 Mar 9;14(6):835-44. Epub 2005 Feb 9.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP/Collège de France.

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http://dx.doi.org/10.1093/hmg/ddi077DOI Listing
March 2005

WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.

Dev Biol 2004 Oct;274(2):260-70

Department of Developmental Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, B.P. 10142, 67404 Illkirch Cedex, C.U. de Strasbourg, France.

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http://dx.doi.org/10.1016/j.ydbio.2004.07.009DOI Listing
October 2004

CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion.

Eur J Immunol 2004 Apr;34(4):1217-27

Department of Pharmacology and Therapeutics, University of Manitoba, Division of Neuroscience, St. Boniface Hospital Research Centre, Winnipeg, Canada.

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http://dx.doi.org/10.1002/eji.200324726DOI Listing
April 2004

NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes.

Exp Cell Res 2003 Sep;289(1):95-107

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP 10142, 67404 Illkirch, C.U. de Strasbourg, France.

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http://dx.doi.org/10.1016/s0014-4827(03)00222-2DOI Listing
September 2003

82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization.

Hum Mol Genet 2003 Jul;12(14):1689-98

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP 10142, 1 rue Laurent Fries, 67404 Illkirch Cedex, France.

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http://dx.doi.org/10.1093/hmg/ddg181DOI Listing
July 2003

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

Neuron 2003 Jun;38(6):887-98

Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Boite Postale 10142, 67404 Illkirch, Cedex, France.

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http://dx.doi.org/10.1016/s0896-6273(03)00354-4DOI Listing
June 2003

Transcriptional regulation of glial cell specification.

Dev Biol 2003 Mar;255(1):138-50

Institut de Génétique et Biologie Moléculaire et Cellulaire, IGBMC/CNRS/ULP/INSERM - BP 10142 67404 Illkirch, c.u., de Strasbourg, France.

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http://dx.doi.org/10.1016/s0012-1606(02)00081-7DOI Listing
March 2003

Novel features of dFMR1, the Drosophila orthologue of the fragile X mental retardation protein.

Neurobiol Dis 2002 Oct;11(1):53-63

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, B.P.163, 67404 Illkirch Cedex, C.U. de Strasbourg, France.

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http://dx.doi.org/10.1006/nbdi.2002.0510DOI Listing
October 2002