Annemieke Madder

Annemieke Madder

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Annemieke Madder

Publications by authors named "Annemieke Madder"

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Untapped Opportunities of Resin-to-Resin Transfer Reactions (RRTR) for the Convergent Assembly of Multivalent Peptide Conjugates.

Chemistry 2020 Apr 18;26(21):4701-4705. Epub 2020 Mar 18.

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 (S4), 9000, Ghent, Belgium.

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http://dx.doi.org/10.1002/chem.202000434DOI Listing
April 2020

Identification of the Molecular Determinants Involved in Antimicrobial Activity of Pseudodesmin A, a Cyclic Lipopeptide From the Viscosin Group.

Front Microbiol 2020 21;11:646. Epub 2020 Apr 21.

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.3389/fmicb.2020.00646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187754PMC
April 2020

PNA-Based MicroRNA Detection Methodologies.

Molecules 2020 Mar 12;25(6). Epub 2020 Mar 12.

Organic and Biomimetic Chemistry Research Group, Ghent University, Krijgslaan 281 S4, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.3390/molecules25061296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144472PMC
March 2020

Exploiting Double Exchange Diels-Alder Cycloadditions for Immobilization of Peptide Nucleic Acids on Gold Nanoparticles.

Front Chem 2020 23;8. Epub 2020 Jan 23.

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.3389/fchem.2020.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989547PMC
January 2020

Synthetic biomolecules: from blind watchmakers to synthetic biologists.

Curr Opin Chem Biol 2019 10;52:A3-A5

Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281, B-9000 Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2019.10.002DOI Listing
October 2019

Furan Cross-Linking Technology for Investigating GPCR-Ligand Interactions.

Methods Mol Biol 2019 ;1947:81-102

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-9121-1_5DOI Listing
August 2019

Counteracting in Vitro Toxicity of the Ionophoric Mycotoxin Beauvericin-Synthetic Receptors to the Rescue.

J Org Chem 2019 08 8;84(16):10422-10435. Epub 2019 Aug 8.

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry , Ghent University , Krijgslaan 281 , 9000 Ghent , Belgium.

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http://dx.doi.org/10.1021/acs.joc.9b01665DOI Listing
August 2019

Thermoresponsive DNA by Intercalation of dsDNA with Oligoethylene-Glycol-Functionalized Small-Molecule Intercalators.

Macromol Rapid Commun 2019 May 6;40(10):e1800900. Epub 2019 Feb 6.

Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1002/marc.201800900DOI Listing
May 2019

Teixobactins: a new class of 21st century antibiotics to combat multidrug-resistant bacterial pathogens.

Future Microbiol 2019 04 29;14:457-460. Epub 2019 Apr 29.

School of Pharmacy, University of Lincoln, Beevor St, Lincoln, LN6 7DL, UK.

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http://dx.doi.org/10.2217/fmb-2019-0056DOI Listing
April 2019

An Anticaffeine Antibody-Oligonucleotide Conjugate for DNA-Directed Immobilization in Environmental Immunoarrays.

Langmuir 2018 12 22;34(49):14834-14841. Epub 2018 Aug 22.

Ghent University , Faculty of Sciences, Department of Organic and Macromolecular Chemistry, Organic and Biomimetic Chemistry Research Group , Krijgslaan 281 (S4) , 9000 Ghent , Belgium.

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http://dx.doi.org/10.1021/acs.langmuir.8b01347DOI Listing
December 2018

Tethered imidazole mediated duplex stabilization and its potential for aptamer stabilization.

Nucleic Acids Res 2018 12;46(22):11671-11686

Department of Organic and Macromolecular Chemistry, NMR and Structure Analysis Research Group, Ghent University, Gent, Oost-Vlaanderen 9000, Belgium.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky1062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294506PMC
December 2018

Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides.

J Med Chem 2018 11 26;61(21):9784-9789. Epub 2018 Oct 26.

Research Group of Organic Chemistry , Vrije Universiteit Brussel , Pleinlaan 2 , Brussels B-1050 , Belgium.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01282DOI Listing
November 2018

Reviving old protecting group chemistry for site-selective peptide-protein conjugation.

Chem Commun (Camb) 2018 Oct 4;54(84):11929-11932. Epub 2018 Oct 4.

OBCR Group, Dept. of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, Ghent, 9000, Belgium.

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http://dx.doi.org/10.1039/c8cc06684aDOI Listing
October 2018

Development of a Synthetic Receptor for the Food Toxin Beauvericin: A Tale of Carbazole and Steroids.

Org Lett 2018 10 10;20(20):6368-6371. Epub 2018 Oct 10.

Department of Organic Chemistry, Organic and Biomimetic Chemistry Research Group , Ghent University , Krijgslaan 281 , Ghent , Belgium.

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http://dx.doi.org/10.1021/acs.orglett.8b02630DOI Listing
October 2018

Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis.

Biomedicines 2018 Oct 30;6(4). Epub 2018 Oct 30.

Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium.

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http://dx.doi.org/10.3390/biomedicines6040099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315747PMC
October 2018

Oxygen Consumption Rate Analysis of Mitochondrial Dysfunction Caused by Cereulide in Caco-2 and HepG2 Cells.

Toxins (Basel) 2018 07 2;10(7). Epub 2018 Jul 2.

Department of Food Technology, Food Safety and Health, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.

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http://dx.doi.org/10.3390/toxins10070266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070949PMC
July 2018

Synthetic Protocol for AFCS: A Biologically Active Fluorescent Castasterone Analog Conjugated to an Alexa Fluor 647 Dye.

Methods Mol Biol 2017 ;1564:9-21

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, 9000, Gent, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-6813-8_2DOI Listing
February 2018

Synthesis and Improved Cross-Linking Properties of C5-Modified Furan Bearing PNAs.

Molecules 2017 Nov 20;22(11). Epub 2017 Nov 20.

Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.

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http://dx.doi.org/10.3390/molecules22112010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150320PMC
November 2017

Visible-Light-Mediated Selective Arylation of Cysteine in Batch and Flow.

Angew Chem Int Ed Engl 2017 10 1;56(41):12702-12707. Epub 2017 Sep 1.

Eindhoven University of Technology, Department of Chemical Engineering and Chemistry, Den Dolech 2, Eindhoven, 5614 AZ, The Netherlands.

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http://dx.doi.org/10.1002/anie.201706700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656832PMC
October 2017

Singlet oxygen-mediated one-pot chemoselective peptide-peptide ligation.

Org Biomol Chem 2017 Oct;15(38):8140-8144

Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Gent, Belgium.

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http://dx.doi.org/10.1039/c7ob02245jDOI Listing
October 2017

Cross-Linking Furan-Modified Kisspeptin-10 to the KISS Receptor.

ACS Chem Biol 2017 08 17;12(8):2191-2200. Epub 2017 Jul 17.

Organic and Biomimetic Chemistry Research Group, Ghent University , Krijgslaan 281 S4, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1021/acschembio.7b00396DOI Listing
August 2017

Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor.

Chem Commun (Camb) 2017 Jun;53(49):6653-6656

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281, S4, B-9000, Gent, Belgium.

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http://dx.doi.org/10.1039/c7cc01705gDOI Listing
June 2017

Porphyrin-based photosensitizers and their DNA conjugates for singlet oxygen induced nucleic acid interstrand crosslinking.

Org Biomol Chem 2017 Jun;15(25):5402-5409

Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1039/c7ob01269aDOI Listing
June 2017

In Vivo Imaging of the Stability and Sustained Cargo Release of an Injectable Amphipathic Peptide-Based Hydrogel.

Biomacromolecules 2017 03 20;18(3):994-1001. Epub 2017 Feb 20.

Research Group of Organic Chemistry, Vrije Universiteit Brussel , Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1021/acs.biomac.6b01840DOI Listing
March 2017

Photoinduced Cross-Linking of Short Furan-Modified DNA on Surfaces.

Langmuir 2017 02 27;33(5):1197-1201. Epub 2017 Jan 27.

Department of Analytical Chemistry; Reference Materials, BAM Federal Institute for Materials Research and Testing , Richard-Willstätter-Str. 11, D-12489 Berlin, Germany.

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http://dx.doi.org/10.1021/acs.langmuir.6b03855DOI Listing
February 2017

Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities.

Chem Commun (Camb) 2017 Feb;53(12):2016-2019

School of Pharmacy, JBL Building, University of Lincoln, Beevor St., Lincoln LN6 7DL, UK.

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http://dx.doi.org/10.1039/c6cc09490bDOI Listing
February 2017

Automated Synthesis of Monodisperse Oligomers, Featuring Sequence Control and Tailored Functionalization.

J Am Chem Soc 2016 11 21;138(43):14182-14185. Epub 2016 Oct 21.

Department of Organic and Macromolecular Chemistry, Ghent University , Krijgslaan 281 S4, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1021/jacs.6b07120DOI Listing
November 2016

Bioconjugation - using selective chemistry to enhance the properties of proteins and peptides as therapeutics and carriers.

Org Biomol Chem 2016 Sep 27;14(34):8002-13. Epub 2016 Jul 27.

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281, Ghent, 9000, Belgium.

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http://dx.doi.org/10.1039/c6ob00808aDOI Listing
September 2016

Danger-associated peptide signaling in Arabidopsis requires clathrin.

Proc Natl Acad Sci U S A 2016 09 20;113(39):11028-33. Epub 2016 Sep 20.

Department of Plant Systems Biology, VIB, 9052 Ghent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047203PMC
http://dx.doi.org/10.1073/pnas.1605588113DOI Listing
September 2016

The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation.

J Exp Bot 2016 08 16;67(16):4877-87. Epub 2016 Jun 16.

Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium Institut Jean-Pierre Bourgin, UMR1318 INRA-AgroParisTech, Saclay Plant Science, F-78026 Versailles, France

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http://dx.doi.org/10.1093/jxb/erw241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983112PMC
August 2016

Singlet Oxygen-Induced Furan Oxidation for Site-Specific and Chemoselective Peptide Ligation.

Chemistry 2016 06 26;22(25):8457-61. Epub 2016 Apr 26.

Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000, Gent, Belgium.

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http://dx.doi.org/10.1002/chem.201601113DOI Listing
June 2016

Chemical Protein Modification through Cysteine.

Chembiochem 2016 Apr 9;17(7):529-53. Epub 2016 Mar 9.

Organic & Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281, 9000, Gent, Belgium.

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http://dx.doi.org/10.1002/cbic.201500667DOI Listing
April 2016

Efficient total syntheses and biological activities of two teixobactin analogues.

Chem Commun (Camb) 2016 Apr;52(36):6060-3

School of Pharmacy, JBL Building, University of Lincoln, Beevor St. Lincoln LN67DL, UK.

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http://dx.doi.org/10.1039/c5cc10249aDOI Listing
April 2016

First total synthesis of WLIP: on the importance of correct protecting group choice.

J Pept Sci 2016 Mar;22(3):149-55

Department of Organic and Macromolecular Chemistry, Organic and Biomimetic Chemistry Research Group, Ghent University, Krijgslaan 281 S4, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1002/psc.2852DOI Listing
March 2016

Mixed α/β-Peptides as a Class of Short Amphipathic Peptide Hydrogelators with Enhanced Proteolytic Stability.

Biomacromolecules 2016 Feb 25;17(2):437-45. Epub 2016 Jan 25.

Department of Pharmaceutical Chemistry and Drug Analysis, Vrije Universiteit Brussel , Laarbeeklaan 103, B-1090 Brussels, Belgium.

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http://dx.doi.org/10.1021/acs.biomac.5b01319DOI Listing
February 2016

Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates.

Chem Commun (Camb) 2015 Dec;51(99):17552-5

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 (S4), B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1039/c5cc07097jDOI Listing
December 2015

Hyphenation of a Deoxyribonuclease I immobilized enzyme reactor with liquid chromatography for the online stability evaluation of oligonucleotides.

J Chromatogr A 2015 Nov 26;1422:18-26. Epub 2015 Oct 26.

Separation Science Group, Department of Organic and Macromolecular Chemistry, Universiteit Gent, Krijgslaan 281 S4-bis, 9000 Gent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2015.10.015DOI Listing
November 2015

The GLV6/RGF8/CLEL2 peptide regulates early pericycle divisions during lateral root initiation.

J Exp Bot 2015 Aug 10;66(17):5245-56. Epub 2015 Jul 10.

Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium. Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium. INRA, UMR1318, Institut Jean-Pierre Bourgin, RD10, F-78000 Versailles, France. AgroParisTech, Institut Jean-Pierre Bourgin, RD10, F-78000 Versailles, France.

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http://dx.doi.org/10.1093/jxb/erv329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526922PMC
August 2015

An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2014 18;31(10):1751-9. Epub 2014 Sep 18.

a Laboratory of Food Analysis , Ghent University , Ghent , Belgium.

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http://dx.doi.org/10.1080/19440049.2014.955887DOI Listing
June 2015

Cyclodextrin-peptide conjugates for sequence specific DNA binding.

Org Biomol Chem 2015 May;13(18):5273-8

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 (S4), B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1039/c5ob00609kDOI Listing
May 2015

Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake.

Org Biomol Chem 2015 Apr;13(13):3856-62

Organic and Biomimetic Chemistry Research Group, Krijgslaan 281, S4, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1039/c4ob02659dDOI Listing
April 2015

Triplex crosslinking through furan oxidation requires perturbation of the structured triple-helix.

Chembiochem 2015 Mar 28;16(4):651-8. Epub 2015 Jan 28.

Organic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281, S4, 9000 Gent (Belgium).

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http://dx.doi.org/10.1002/cbic.201402602DOI Listing
March 2015

Rational design of a hexapeptide hydrogelator for controlled-release drug delivery.

J Mater Chem B 2015 Feb 2;3(5):759-765. Epub 2014 Dec 2.

Research Group of Organic Chemistry, Vrije Universiteit Brussel, Pleinlaan 2, Brussels, B-1050, Belgium.

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http://dx.doi.org/10.1039/c4tb01294aDOI Listing
February 2015

Cyclic lipodepsipeptides produced by Pseudomonas spp. naturally present in raw milk induce inhibitory effects on microbiological inhibitor assays for antibiotic residue screening.

PLoS One 2014 22;9(5):e98266. Epub 2014 May 22.

Institute for Agricultural and Fisheries Research (ILVO), Technology and Food Science Unit, Melle, Belgium; Ghent University (UGent), Department of Pathology, Bacteriology and Poultry Diseases, Merelbeke, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098266PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031126PMC
January 2015

Identification of a pKa-regulating motif stabilizing imidazole-modified double-stranded DNA.

Nucleic Acids Res 2015 Jan 17;43(1):51-62. Epub 2014 Dec 17.

Department of Organic and Macromolecular Chemistry, Organic and Biomimetic Chemistry Research Group, Ghent University, Gent, Oost-Vlaanderen 9000, Belgium

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http://nar.oxfordjournals.org/content/43/1/51.full.pdf
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gku1306
Publisher Site
http://dx.doi.org/10.1093/nar/gku1306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288195PMC
January 2015

Water-soluble NHC-Cu catalysts: applications in click chemistry, bioconjugation and mechanistic analysis.

Org Biomol Chem 2014 Dec 24;12(46):9350-6. Epub 2014 Sep 24.

Laboratory of Organometallics, Catalysis and Ordered Materials, State Key Laboratory of Advanced Technology for Materials Synthesis and Processing; Center for Chemical and Material Engineering, Wuhan University of Technology; Department of Applied Chemistry, Faculty of Sciences, Wuhan University of Technology, Wuhan 430070, P.R. China.

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http://dx.doi.org/10.1039/c4ob01350fDOI Listing
December 2014

Impact of a stereocentre inversion in cyclic lipodepsipeptides from the viscosin group: a comparative study of the viscosinamide and pseudodesmin conformation and self-assembly.

Chembiochem 2014 Dec 7;15(18):2736-46. Epub 2014 Nov 7.

NMR and Structure Analysis Unit, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent (Belgium).

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http://dx.doi.org/10.1002/cbic.201402389DOI Listing
December 2014

XVIth symposium on chemistry of nucleic acid components.

Chembiochem 2014 Nov 22;15(17):2495-8. Epub 2014 Sep 22.

Department of Organic Chemistry, Gent University, Krijgslaan 281, 9000 Gent (Belgium).

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http://dx.doi.org/10.1002/cbic.201402460DOI Listing
November 2014

Versatile synthesis of amino acid functionalized nucleosides via a domino carboxamidation reaction.

Beilstein J Org Chem 2014 4;10:2566-72. Epub 2014 Nov 4.

Department of Organic and Macromolecular Chemistry, Organic and Biomimetic Chemistry Research Group, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium.

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http://www.beilstein-journals.org/bjoc/content/10/1/268
Publisher Site
http://dx.doi.org/10.3762/bjoc.10.268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222392PMC
November 2014

Rapid total synthesis of cyclic lipodepsipeptides as a premise to investigate their self-assembly and biological activity.

Chemistry 2014 Jun 9;20(25):7766-75. Epub 2014 May 9.

Department of Organic Chemistry, Organic and Biomimetic Chemistry Research Group, Ghent University, Krijgslaan 281 S4, 9000 Ghent (Belgium); Department of Organic Chemistry, NMR and Structure Analysis Unit, Ghent University, Krijgslaan 281 S4, 9000 Ghent (Belgium).

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http://dx.doi.org/10.1002/chem.201402066DOI Listing
June 2014

A synthetic oligonucleotide model for evaluating the oxidation and crosslinking propensities of natural furan-modified DNA.

Chembiochem 2014 Jan 9;15(1):103-7. Epub 2013 Dec 9.

Organic and Biomimetic Chemistry Research Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Gent (Belgium).

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http://dx.doi.org/10.1002/cbic.201300612DOI Listing
January 2014

The antimicrobial compound xantholysin defines a new group of Pseudomonas cyclic lipopeptides.

PLoS One 2013 17;8(5):e62946. Epub 2013 May 17.

Centre of Microbial and Plant Genetics, Department of Microbial and Molecular Systems, University of Leuven, Heverlee-Leuven, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656897PMC
December 2013

Multifunctionalized sequence-defined oligomers from a single building block.

Angew Chem Int Ed Engl 2013 Dec 31;52(50):13261-4. Epub 2013 Oct 31.

Polymer Chemistry Research Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281, S4, 9000 Gent (Belgium).

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http://dx.doi.org/10.1002/anie.201307439DOI Listing
December 2013

Toxicity inspired cross-linking for probing DNA-peptide interactions.

Bioconjug Chem 2013 Dec 19;24(12):2008-14. Epub 2013 Nov 19.

Organic and Biomimetic Chemistry Research Group, Department of Organic Chemistry, Ghent University , Krijgslaan 281-S4, 9000 Gent, Belgium.

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http://dx.doi.org/10.1021/bc400327qDOI Listing
December 2013

DNA interstrand cross-link formation using furan as a masked reactive aldehyde.

Curr Protoc Nucleic Acid Chem 2013 Oct 8;54:5.12.1-5.12.16. Epub 2013 Oct 8.

Organic and Biomimetic Chemistry Research Group, Department of Organic Chemistry, Ghent University, Krijgslaan, Ghent, Belgium.

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http://dx.doi.org/10.1002/0471142700.nc0512s54DOI Listing
October 2013

Patchwork protein chemistry: a practitioner's treatise on the advances in synthetic peptide stitchery.

Chembiochem 2013 Jun;14(9):1032-48

Organic and Biomimetic Chemistry Research Group, Department of Organic Chemistry, Faculty of Sciences, Ghent University, Krijgslaan 281 (S4), 9000 Ghent, Belgium.

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http://dx.doi.org/10.1002/cbic.201200775DOI Listing
June 2013

Exploiting furan's versatile reactivity in reversible and irreversible orthogonal peptide labeling.

Chem Commun (Camb) 2013 Apr;49(28):2927-9

Organic and Biomimetic Chemistry Research Group, Krijgslaan 281, S4, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1039/c3cc40588eDOI Listing
April 2013

Fast RNA conjugations on solid phase by strain-promoted cycloadditions.

Org Biomol Chem 2012 Sep 2;10(33):6633-9. Epub 2012 Jul 2.

Department of Chemistry, NUI Maynooth, Maynooth, Republic of Ireland.

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http://dx.doi.org/10.1039/c2ob25628bDOI Listing
September 2012

Sequence specific DNA cross-linking triggered by visible light.

J Am Chem Soc 2012 Jul 25;134(26):10737-40. Epub 2012 Jun 25.

Laboratory for Organic and Biomimetic Chemistry, University of Ghent, Krijgslaan 281 S4, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1021/ja301901pDOI Listing
July 2012

Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges.

Expert Rev Vaccines 2012 Jun;11(6):695-719

Laboratory of Virology, Department of Virology, Parasitology and Immunology, Ghent University, Merelbeke, Belgium.

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http://dx.doi.org/10.1586/erv.12.38DOI Listing
June 2012

Aromatic capping surprisingly stabilizes furan moieties in peptides against acidic degradation.

Org Biomol Chem 2012 May 19;10(20):3999-4002. Epub 2012 Apr 19.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Krijgslaan 281, S4, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1039/c2ob25548kDOI Listing
May 2012

Shortcut access to peptidosteroid conjugates: building blocks for solid-phase bile acid scaffold decoration by convergent ligation.

Molecules 2011 Dec 7;16(12):10168-86. Epub 2011 Dec 7.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Faculty of Sciences, Ghent University, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.3390/molecules161210168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264362PMC
December 2011

Furan-oxidation-triggered inducible DNA cross-linking: acyclic versus cyclic furan-containing building blocks--on the benefit of restoring the cyclic sugar backbone.

Chemistry 2011 Jun 20;17(25):6940-53. Epub 2011 May 20.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Ghent University, Krijgslaan 281, S4, 9000 Gent, Belgium.

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http://dx.doi.org/10.1002/chem.201100067DOI Listing
June 2011

Synthesis and incorporation of a furan-modified adenosine building block for DNA interstrand crosslinking.

Chem Commun (Camb) 2011 Mar 2;47(10):2796-8. Epub 2011 Feb 2.

Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, NL-6525 AJ, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1039/c0cc04667aDOI Listing
March 2011

Unprecedented C-selective interstrand cross-linking through in situ oxidation of furan-modified oligodeoxynucleotides.

J Am Chem Soc 2011 Feb 16;133(4):796-807. Epub 2010 Dec 16.

Laboratory for Organic and Biomimetic Chemistry, University of Ghent, Krijgslaan 281 S4, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1021/ja1048169DOI Listing
February 2011

Surprising duplex stabilisation upon mismatch introduction within triply modified duplexes.

Bioorg Chem 2010 Jun 18;38(3):92-7. Epub 2010 Jan 18.

Ghent University, Department of Organic Chemistry, Krijgslaan, Belgium.

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http://dx.doi.org/10.1016/j.bioorg.2010.01.002DOI Listing
June 2010

Towards the conformational mimicry of the measles virus HNE loop: design, synthesis and biological evaluation of a cyclic bile acid-peptide conjugate.

Org Biomol Chem 2009 Sep 7;7(17):3391-9. Epub 2009 Jul 7.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Ghent University, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1039/b907395gDOI Listing
September 2009

Furan-modified oligonucleotides for fast, high-yielding and site-selective DNA inter-strand cross-linking with non-modified complements.

Nucleic Acids Res 2009 Apr 16;37(5):1555-65. Epub 2009 Jan 16.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Ghent University, Krijgslaan 281, S4, 9000 Gent, Belgium.

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http://dx.doi.org/10.1093/nar/gkn1077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655669PMC
April 2009

From DNA cross-linking to peptide labeling: on the versatility of the furan-oxidation-conjugation strategy.

Chem Commun (Camb) 2009 Jan 1(3):340-2. Epub 2008 Dec 1.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Krijgslaan 281, S4; B-9000 Gent, Belgium.

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http://dx.doi.org/10.1039/b817447dDOI Listing
January 2009

Validation of a solid-phase-bound steroid scaffold for the synthesis of novel cyclic peptidosteroids.

J Pept Sci 2007 Nov;13(11):702-8

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Ghent University, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1002/psc.868DOI Listing
November 2007

Synthesis of functionalised nucleosides for incorporation into nucleic acid-based serine protease mimics.

Molecules 2007 Jan 31;12(1):114-29. Epub 2007 Jan 31.

Ghent University, Department of Organic Chemistry, Laboratory for Organic and Biomimetic Chemistry, Krijgslaan 281 (S4), Gent, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149322PMC
http://dx.doi.org/10.3390/12010114DOI Listing
January 2007

Fine-tuning furan toxicity: fast and quantitative DNA interchain cross-link formation upon selective oxidation of a furan containing oligonucleotide.

Chem Commun (Camb) 2005 Feb 4(7):936-8. Epub 2005 Jan 4.

Laboratory for Organic and Biomimetic Chemistry, Department of Organic Chemistry, Krijgslaan 281, S4, 9000, Gent, Belgium.

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http://dx.doi.org/10.1039/b415092aDOI Listing
February 2005

Stabilisation of RNA bulges by oligonucleotide complements containing an adenosine analogue.

Chembiochem 2003 Nov;4(11):1194-200

Division of Organic and Bioorganic Chemistry, MBB, Scheele Laboratory, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1002/cbic.200300531DOI Listing
November 2003

Evaluation of a two-stage screening procedure in the combinatorial search for serine protease-like activity.

J Comb Chem 2002 Nov-Dec;4(6):552-62

Laboratory of Organic Synthesis, Department of Organic Chemistry, Ghent University, Krijgslaan 281, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1021/cc020016gDOI Listing
January 2003

Stepwise Approach toward First Generation Nonenzymatic Hydrolases.

J Org Chem 1998 Apr;63(8):2548-2559

Laboratoire de Chimie Physique et de Cristallographie, Université Catholique de Louvain, 1 Place Louis Pasteur, B-1348 Louvain-la Neuve, Belgium.

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http://dx.doi.org/10.1021/jo971935+DOI Listing
April 1998