Annemarie Poustka

Annemarie Poustka

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Annemarie Poustka

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A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.

Authors:
Jillian P Casey Tiago Magalhaes Judith M Conroy Regina Regan Naisha Shah Richard Anney Denis C Shields Brett S Abrahams Joana Almeida Elena Bacchelli Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Patrick F Bolton Thomas Bourgeron Sean Brennan Phil Cali Catarina Correia Christina Corsello Marc Coutanche Geraldine Dawson Maretha de Jonge Richard Delorme Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Suzanne Foley Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jonathan Green Stephen J Guter Hakon Hakonarson Richard Holt Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Janine A Lamb Marion Leboyer Ann Le Couteur Bennett L Leventhal Catherine Lord Sabata C Lund Elena Maestrini Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Alison Merikangas Judith Miller Fiorella Minopoli Ghazala K Mirza Jeff Munson Stanley F Nelson Gudrun Nygren Guiomar Oliveira Alistair T Pagnamenta Katerina Papanikolaou Jeremy R Parr Barbara Parrini Andrew Pickles Dalila Pinto Joseph Piven David J Posey Annemarie Poustka Fritz Poustka Jiannis Ragoussis Bernadette Roge Michael L Rutter Ana F Sequeira Latha Soorya Inês Sousa Nuala Sykes Vera Stoppioni Raffaella Tancredi Maïté Tauber Ann P Thompson Susanne Thomson John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Jacob A S Vorstman Simon Wallace Kai Wang Thomas H Wassink Kathy White Kirsty Wing Kerstin Wittemeyer Brian L Yaspan Lonnie Zwaigenbaum Catalina Betancur Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Daniel H Geschwind Jonathan L Haines Joachim Hallmayer Anthony P Monaco John I Nurnberger Margaret A Pericak-Vance Gerard D Schellenberg Stephen W Scherer James S Sutcliffe Peter Szatmari Veronica J Vieland Ellen M Wijsman Andrew Green Michael Gill Louise Gallagher Astrid Vicente Sean Ennis

Hum Genet 2012 Apr 14;131(4):565-79. Epub 2011 Oct 14.

School of Medicine and Medical Science University College, Dublin, Ireland.

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http://researchrepository.ucd.ie/bitstream/handle/10197/6163
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http://link.springer.com/10.1007/s00439-011-1094-6
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http://dx.doi.org/10.1007/s00439-011-1094-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303079PMC
April 2012

A genome-wide scan for common alleles affecting risk for autism.

Authors:
Richard Anney Lambertus Klei Dalila Pinto Regina Regan Judith Conroy Tiago R Magalhaes Catarina Correia Brett S Abrahams Nuala Sykes Alistair T Pagnamenta Joana Almeida Elena Bacchelli Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Sven Bölte Patrick F Bolton Thomas Bourgeron Sean Brennan Jessica Brian Andrew R Carson Guillermo Casallo Jillian Casey Su H Chu Lynne Cochrane Christina Corsello Emily L Crawford Andrew Crossett Geraldine Dawson Maretha de Jonge Richard Delorme Irene Drmic Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jeremy Goldberg Jonathan Green Stephen J Guter Hakon Hakonarson Elizabeth A Heron Matthew Hill Richard Holt Jennifer L Howe Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Olena Korvatska Vlad Kustanovich Clara M Lajonchere Janine A Lamb Magdalena Laskawiec Marion Leboyer Ann Le Couteur Bennett L Leventhal Anath C Lionel Xiao-Qing Liu Catherine Lord Linda Lotspeich Sabata C Lund Elena Maestrini William Mahoney Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Nadine M Melhem Alison Merikangas Ohsuke Migita Nancy J Minshew Ghazala K Mirza Jeff Munson Stanley F Nelson Carolyn Noakes Abdul Noor Gudrun Nygren Guiomar Oliveira Katerina Papanikolaou Jeremy R Parr Barbara Parrini Tara Paton Andrew Pickles Joseph Piven David J Posey Annemarie Poustka Fritz Poustka Aparna Prasad Jiannis Ragoussis Katy Renshaw Jessica Rickaby Wendy Roberts Kathryn Roeder Bernadette Roge Michael L Rutter Laura J Bierut John P Rice Jeff Salt Katherine Sansom Daisuke Sato Ricardo Segurado Lili Senman Naisha Shah Val C Sheffield Latha Soorya Inês Sousa Vera Stoppioni Christina Strawbridge Raffaella Tancredi Katherine Tansey Bhooma Thiruvahindrapduram Ann P Thompson Susanne Thomson Ana Tryfon John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Simon Wallace Kai Wang Zhouzhi Wang Thomas H Wassink Kirsty Wing Kerstin Wittemeyer Shawn Wood Brian L Yaspan Danielle Zurawiecki Lonnie Zwaigenbaum Catalina Betancur Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Louise Gallagher Daniel H Geschwind Michael Gill Jonathan L Haines Judith Miller Anthony P Monaco John I Nurnberger Andrew D Paterson Margaret A Pericak-Vance Gerard D Schellenberg Stephen W Scherer James S Sutcliffe Peter Szatmari Astrid M Vicente Veronica J Vieland Ellen M Wijsman Bernie Devlin Sean Ennis Joachim Hallmayer

Hum Mol Genet 2010 Oct 27;19(20):4072-82. Epub 2010 Jul 27.

Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland.

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http://hmg.oxfordjournals.org/content/19/20/4072.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddq307
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http://dx.doi.org/10.1093/hmg/ddq307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947401PMC
October 2010

Functional impact of global rare copy number variation in autism spectrum disorders.

Authors:
Dalila Pinto Alistair T Pagnamenta Lambertus Klei Richard Anney Daniele Merico Regina Regan Judith Conroy Tiago R Magalhaes Catarina Correia Brett S Abrahams Joana Almeida Elena Bacchelli Gary D Bader Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Sven Bölte Patrick F Bolton Thomas Bourgeron Sean Brennan Jessica Brian Susan E Bryson Andrew R Carson Guillermo Casallo Jillian Casey Brian H Y Chung Lynne Cochrane Christina Corsello Emily L Crawford Andrew Crossett Cheryl Cytrynbaum Geraldine Dawson Maretha de Jonge Richard Delorme Irene Drmic Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jeremy Goldberg Andrew Green Jonathan Green Stephen J Guter Hakon Hakonarson Elizabeth A Heron Matthew Hill Richard Holt Jennifer L Howe Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Olena Korvatska Vlad Kustanovich Clara M Lajonchere Janine A Lamb Magdalena Laskawiec Marion Leboyer Ann Le Couteur Bennett L Leventhal Anath C Lionel Xiao-Qing Liu Catherine Lord Linda Lotspeich Sabata C Lund Elena Maestrini William Mahoney Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Alison Merikangas Ohsuke Migita Nancy J Minshew Ghazala K Mirza Jeff Munson Stanley F Nelson Carolyn Noakes Abdul Noor Gudrun Nygren Guiomar Oliveira Katerina Papanikolaou Jeremy R Parr Barbara Parrini Tara Paton Andrew Pickles Marion Pilorge Joseph Piven Chris P Ponting David J Posey Annemarie Poustka Fritz Poustka Aparna Prasad Jiannis Ragoussis Katy Renshaw Jessica Rickaby Wendy Roberts Kathryn Roeder Bernadette Roge Michael L Rutter Laura J Bierut John P Rice Jeff Salt Katherine Sansom Daisuke Sato Ricardo Segurado Ana F Sequeira Lili Senman Naisha Shah Val C Sheffield Latha Soorya Inês Sousa Olaf Stein Nuala Sykes Vera Stoppioni Christina Strawbridge Raffaella Tancredi Katherine Tansey Bhooma Thiruvahindrapduram Ann P Thompson Susanne Thomson Ana Tryfon John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Simon Wallace Kai Wang Zhouzhi Wang Thomas H Wassink Caleb Webber Rosanna Weksberg Kirsty Wing Kerstin Wittemeyer Shawn Wood Jing Wu Brian L Yaspan Danielle Zurawiecki Lonnie Zwaigenbaum Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Bernie Devlin Sean Ennis Louise Gallagher Daniel H Geschwind Michael Gill Jonathan L Haines Joachim Hallmayer Judith Miller Anthony P Monaco John I Nurnberger Andrew D Paterson Margaret A Pericak-Vance Gerard D Schellenberg Peter Szatmari Astrid M Vicente Veronica J Vieland Ellen M Wijsman Stephen W Scherer James S Sutcliffe Catalina Betancur

Nature 2010 Jul 9;466(7304):368-72. Epub 2010 Jun 9.

The Centre for Applied Genomics and Program in Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nature09146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021798PMC
July 2010

Reverse-phase protein arrays for application-orientated cancer research.

Proteomics Clin Appl 2009 Oct 4;3(10):1140-50. Epub 2009 Aug 4.

Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/prca.200780035DOI Listing
October 2009

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer.

Breast Cancer Res Treat 2009 Jul 1;116(1):69-77. Epub 2008 Jul 1.

Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10549-008-0105-3DOI Listing
July 2009

Molecular cancer phenotype in normal prostate tissue.

Eur Urol 2009 Apr 16;55(4):885-90. Epub 2008 May 16.

Martini-Clinic, Prostate Cancer Center, University Medical Center Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1016/j.eururo.2008.04.105DOI Listing
April 2009

In vitro-targeted gene identification in patients with hepatitis C using a genome-wide microarray technology.

Hepatology 2009 Feb;49(2):378-86

Department of Internal Medicine, Salem Medical Center, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hep.22677DOI Listing
February 2009

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes.

Lung Cancer 2009 Jan 16;63(1):32-8. Epub 2008 May 16.

Division of Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2008.03.033DOI Listing
January 2009

DMBT1 expression distinguishes anorectal from cutaneous melanoma.

Histopathology 2009 Jan;54(2):233-40

Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1365-2559.2008.03200.xDOI Listing
January 2009

Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells.

Cancer Lett 2008 Dec 26;272(1):160-6. Epub 2008 Aug 26.

Division of Tumour Genetics B030, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.canlet.2008.07.013DOI Listing
December 2008

Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data.

Bioinformatics 2008 Nov 28;24(22):2650-6. Epub 2008 Jan 28.

German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btm634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579711PMC
November 2008

Antibody microarrays as an experimental platform for the analysis of signal transduction networks.

Adv Biochem Eng Biotechnol 2008 ;110:153-75

Division of Molecular Genome Analysis, B050, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/10_2008_101DOI Listing
October 2008

Predicting pathway membership via domain signatures.

Bioinformatics 2008 Oct 1;24(19):2137-42. Epub 2008 Aug 1.

German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btn403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553439PMC
October 2008

Statistical methods and software for the analysis of highthroughput reverse genetic assays using flow cytometry readouts.

Genome Biol 2006 17;7(8):R77. Epub 2006 Aug 17.

Division of Molecular Genome Analysis, German Cancer Research Center, INF 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/gb-2006-7-8-R77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779598PMC
March 2008

Modeling breast cell cycle regulation--overcoming drug resistance.

Conf Proc IEEE Eng Med Biol Soc 2006 ;1:40-3

Div. of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1109/IEMBS.2006.259761DOI Listing
March 2008

Infrared-based protein detection arrays for quantitative proteomics.

Expert Opin Drug Discov 2008 Feb;3(2):273-83

German Cancer Research Center (DKFZ), Department of Molecular Genome Analysis/B050, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany +49 6221 424765 ; +49 6221 423454 ;

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http://dx.doi.org/10.1517/17460441.3.2.273DOI Listing
February 2008

Extending pathways based on gene lists using InterPro domain signatures.

BMC Bioinformatics 2008 Jan 4;9. Epub 2008 Jan 4.

German Cancer Research Center, Molecular Genome Analysis, Im Neuenheimer Feld 580,69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245903PMC
January 2008

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses.

J Mol Med (Berl) 2007 Nov 23;85(11):1253-62. Epub 2007 Jun 23.

Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00109-007-0230-1DOI Listing
November 2007

Large scale statistical inference of signaling pathways from RNAi and microarray data.

BMC Bioinformatics 2007 Oct 15;8:386. Epub 2007 Oct 15.

German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-8-386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241646PMC
October 2007

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer.

Bioinformatics 2007 Sep 28;23(17):2273-80. Epub 2007 Jun 28.

German Cancer Research Center (DKFZ), Department of Molecular Genome Analysis, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btm340DOI Listing
September 2007

High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins.

J Biomol Screen 2007 Jun 3;12(4):510-20. Epub 2007 May 3.

Division of Molecular Genome Analysis, German Cancer Research Centre, Heidelberg, Germany.

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http://dx.doi.org/10.1177/1087057107301271DOI Listing
June 2007

GOSim--an R-package for computation of information theoretic GO similarities between terms and gene products.

BMC Bioinformatics 2007 May 22;8:166. Epub 2007 May 22.

German Cancer Research Center (DKFZ), Div. Molecular Genome Analysis, Im Neuenheimer Feld 580, Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-8-166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892785PMC
May 2007

Combinatorial RNAi for quantitative protein network analysis.

Proc Natl Acad Sci U S A 2007 Apr 9;104(16):6579-84. Epub 2007 Apr 9.

Division of Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.0606827104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1849961PMC
April 2007

Mapping autism risk loci using genetic linkage and chromosomal rearrangements.

Authors:
Peter Szatmari Andrew D Paterson Lonnie Zwaigenbaum Wendy Roberts Jessica Brian Xiao-Qing Liu John B Vincent Jennifer L Skaug Ann P Thompson Lili Senman Lars Feuk Cheng Qian Susan E Bryson Marshall B Jones Christian R Marshall Stephen W Scherer Veronica J Vieland Christopher Bartlett La Vonne Mangin Rhinda Goedken Alberto Segre Margaret A Pericak-Vance Michael L Cuccaro John R Gilbert Harry H Wright Ruth K Abramson Catalina Betancur Thomas Bourgeron Christopher Gillberg Marion Leboyer Joseph D Buxbaum Kenneth L Davis Eric Hollander Jeremy M Silverman Joachim Hallmayer Linda Lotspeich James S Sutcliffe Jonathan L Haines Susan E Folstein Joseph Piven Thomas H Wassink Val Sheffield Daniel H Geschwind Maja Bucan W Ted Brown Rita M Cantor John N Constantino T Conrad Gilliam Martha Herbert Clara Lajonchere David H Ledbetter Christa Lese-Martin Janet Miller Stan Nelson Carol A Samango-Sprouse Sarah Spence Matthew State Rudolph E Tanzi Hilary Coon Geraldine Dawson Bernie Devlin Annette Estes Pamela Flodman Lambertus Klei William M McMahon Nancy Minshew Jeff Munson Elena Korvatska Patricia M Rodier Gerard D Schellenberg Moyra Smith M Anne Spence Chris Stodgell Ping Guo Tepper Ellen M Wijsman Chang-En Yu Bernadette Rogé Carine Mantoulan Kerstin Wittemeyer Annemarie Poustka Bärbel Felder Sabine M Klauck Claudia Schuster Fritz Poustka Sven Bölte Sabine Feineis-Matthews Evelyn Herbrecht Gabi Schmötzer John Tsiantis Katerina Papanikolaou Elena Maestrini Elena Bacchelli Francesca Blasi Simona Carone Claudio Toma Herman Van Engeland Maretha de Jonge Chantal Kemner Frederieke Koop Frederike Koop Marjolein Langemeijer Marjolijn Langemeijer Channa Hijmans Channa Hijimans Wouter G Staal Gillian Baird Patrick F Bolton Michael L Rutter Emma Weisblatt Jonathan Green Catherine Aldred Julie-Anne Wilkinson Andrew Pickles Ann Le Couteur Tom Berney Helen McConachie Anthony J Bailey Kostas Francis Gemma Honeyman Aislinn Hutchinson Jeremy R Parr Simon Wallace Anthony P Monaco Gabrielle Barnby Kazuhiro Kobayashi Janine A Lamb Ines Sousa Nuala Sykes Edwin H Cook Stephen J Guter Bennett L Leventhal Jeff Salt Catherine Lord Christina Corsello Vanessa Hus Daniel E Weeks Fred Volkmar Maïté Tauber Eric Fombonne Andy Shih Kacie J Meyer

Nat Genet 2007 Mar 18;39(3):319-28. Epub 2007 Feb 18.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.

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http://dx.doi.org/10.1038/ng1985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867008PMC
March 2007

Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma.

Eur J Cancer 2007 Feb 11;43(3):607-16. Epub 2007 Jan 11.

Division of Tumour Genetics B030, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2006.09.023DOI Listing
February 2007

Infrared-based protein detection arrays for quantitative proteomics.

Proteomics 2007 Feb;7(4):558-564

Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1002/pmic.200600757DOI Listing
February 2007

CAFTAN: a tool for fast mapping, and quality assessment of cDNAs.

BMC Bioinformatics 2006 Oct 25;7:473. Epub 2006 Oct 25.

DKFZ, German Cancer Research Center, Division Molecular Biophysics, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-7-473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636072PMC
October 2006

An anthropoid-specific segmental duplication on human chromosome 1q22.

Genomics 2006 Aug 20;88(2):143-51. Epub 2006 Mar 20.

Department of Molecular Genome Analysis, DKFZ-German Cancer Research Center, INF 580, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ygeno.2006.02.002DOI Listing
August 2006

Molecular characterization of the porcine deleted in malignant brain tumors 1 gene (DMBT1).

Gene 2006 Jul 20;376(2):184-91. Epub 2006 Mar 20.

Institute of Genetics, Vetsuisse Faculty, University of Berne, Bremgartenstrasse 109a, 3001 Berne, Switzerland.

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http://dx.doi.org/10.1016/j.gene.2006.03.002DOI Listing
July 2006

Parameter estimation for the calibration and variance stabilization of microarray data.

Stat Appl Genet Mol Biol 2003 5;2:Article3. Epub 2003 Apr 5.

German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.2202/1544-6115.1008DOI Listing
May 2006

A compendium to ensure computational reproducibility in high-dimensional classification tasks.

Stat Appl Genet Mol Biol 2004 19;3:Article37. Epub 2004 Dec 19.

Division of Molecular Genome Analysis, German Cancer Research Centre.

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http://dx.doi.org/10.2202/1544-6115.1078DOI Listing
May 2006

The 3of5 web application for complex and comprehensive pattern matching in protein sequences.

BMC Bioinformatics 2006 Mar 16;7:144. Epub 2006 Mar 16.

Division of Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-7-144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523217PMC
March 2006

The systematic functional characterisation of Xq28 genes prioritises candidate disease genes.

BMC Genomics 2006 Feb 17;7:29. Epub 2006 Feb 17.

Division of Molecular Genome Analysis, German Cancer Research Centre (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2164-7-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431524PMC
February 2006

The LIFEdb database in 2006.

Nucleic Acids Res 2006 Jan;34(Database issue):D415-8

Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/nar/gkj139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347501PMC
January 2006

Systematic comparison of surface coatings for protein microarrays.

Proteomics 2005 Dec;5(18):4705-12

Department of Molecular Genome Analysis, German Cancer Research Center, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1002/pmic.200401324DOI Listing
December 2005

Utility of lab-on-a-chip technology for high-throughput nucleic acid and protein analysis.

Electrophoresis 2005 Oct;26(19):3674-81

Department of Global Sciences and Information, AstraZeneca, Mereside, Alderley Park, Cheshire, UK.

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http://dx.doi.org/10.1002/elps.200500166DOI Listing
October 2005

Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes.

BMC Biol 2005 Jul 19;3:16. Epub 2005 Jul 19.

Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1186/1741-7007-3-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198218PMC
July 2005

Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1.

Protein Expr Purif 2005 Jun;41(2):275-86

Institute of Molecular Biology and Cell Culture Technology, University of Applied Sciences Mannheim, Windeckstrasse 98, 68163 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.pep.2005.02.010DOI Listing
June 2005

Multiplex reverse transcription-polymerase chain reaction combined with on-chip electrophoresis as a rapid screening tool for candidate gene sets.

Electrophoresis 2005 May;26(9):1687-91

Molecular Genome Analysis, Deutsches Krebsforschungs-zentrum (DKFZ), Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1002/elps.200410237DOI Listing
May 2005

The DNA sequence of the human X chromosome.

Authors:
Mark T Ross Darren V Grafham Alison J Coffey Steven Scherer Kirsten McLay Donna Muzny Matthias Platzer Gareth R Howell Christine Burrows Christine P Bird Adam Frankish Frances L Lovell Kevin L Howe Jennifer L Ashurst Robert S Fulton Ralf Sudbrak Gaiping Wen Matthew C Jones Matthew E Hurles T Daniel Andrews Carol E Scott Stephen Searle Juliane Ramser Adam Whittaker Rebecca Deadman Nigel P Carter Sarah E Hunt Rui Chen Andrew Cree Preethi Gunaratne Paul Havlak Anne Hodgson Michael L Metzker Stephen Richards Graham Scott David Steffen Erica Sodergren David A Wheeler Kim C Worley Rachael Ainscough Kerrie D Ambrose M Ali Ansari-Lari Swaroop Aradhya Robert I S Ashwell Anne K Babbage Claire L Bagguley Andrea Ballabio Ruby Banerjee Gary E Barker Karen F Barlow Ian P Barrett Karen N Bates David M Beare Helen Beasley Oliver Beasley Alfred Beck Graeme Bethel Karin Blechschmidt Nicola Brady Sarah Bray-Allen Anne M Bridgeman Andrew J Brown Mary J Brown David Bonnin Elspeth A Bruford Christian Buhay Paula Burch Deborah Burford Joanne Burgess Wayne Burrill John Burton Jackie M Bye Carol Carder Laura Carrel Joseph Chako Joanne C Chapman Dean Chavez Ellson Chen Guan Chen Yuan Chen Zhijian Chen Craig Chinault Alfredo Ciccodicola Sue Y Clark Graham Clarke Chris M Clee Sheila Clegg Kerstin Clerc-Blankenburg Karen Clifford Vicky Cobley Charlotte G Cole Jen S Conquer Nicole Corby Richard E Connor Robert David Joy Davies Clay Davis John Davis Oliver Delgado Denise Deshazo Pawandeep Dhami Yan Ding Huyen Dinh Steve Dodsworth Heather Draper Shannon Dugan-Rocha Andrew Dunham Matthew Dunn K James Durbin Ireena Dutta Tamsin Eades Matthew Ellwood Alexandra Emery-Cohen Helen Errington Kathryn L Evans Louisa Faulkner Fiona Francis John Frankland Audrey E Fraser Petra Galgoczy James Gilbert Rachel Gill Gernot Glöckner Simon G Gregory Susan Gribble Coline Griffiths Russell Grocock Yanghong Gu Rhian Gwilliam Cerissa Hamilton Elizabeth A Hart Alicia Hawes Paul D Heath Katja Heitmann Steffen Hennig Judith Hernandez Bernd Hinzmann Sarah Ho Michael Hoffs Phillip J Howden Elizabeth J Huckle Jennifer Hume Paul J Hunt Adrienne R Hunt Judith Isherwood Leni Jacob David Johnson Sally Jones Pieter J de Jong Shirin S Joseph Stephen Keenan Susan Kelly Joanne K Kershaw Ziad Khan Petra Kioschis Sven Klages Andrew J Knights Anna Kosiura Christie Kovar-Smith Gavin K Laird Cordelia Langford Stephanie Lawlor Margaret Leversha Lora Lewis Wen Liu Christine Lloyd David M Lloyd Hermela Loulseged Jane E Loveland Jamieson D Lovell Ryan Lozado Jing Lu Rachael Lyne Jie Ma Manjula Maheshwari Lucy H Matthews Jennifer McDowall Stuart McLaren Amanda McMurray Patrick Meidl Thomas Meitinger Sarah Milne George Miner Shailesh L Mistry Margaret Morgan Sidney Morris Ines Müller James C Mullikin Ngoc Nguyen Gabriele Nordsiek Gerald Nyakatura Christopher N O'Dell Geoffery Okwuonu Sophie Palmer Richard Pandian David Parker Julia Parrish Shiran Pasternak Dina Patel Alex V Pearce Danita M Pearson Sarah E Pelan Lesette Perez Keith M Porter Yvonne Ramsey Kathrin Reichwald Susan Rhodes Kerry A Ridler David Schlessinger Mary G Schueler Harminder K Sehra Charles Shaw-Smith Hua Shen Elizabeth M Sheridan Ratna Shownkeen Carl D Skuce Michelle L Smith Elizabeth C Sotheran Helen E Steingruber Charles A Steward Roy Storey R Mark Swann David Swarbreck Paul E Tabor Stefan Taudien Tineace Taylor Brian Teague Karen Thomas Andrea Thorpe Kirsten Timms Alan Tracey Steve Trevanion Anthony C Tromans Michele d'Urso Daniel Verduzco Donna Villasana Lenee Waldron Melanie Wall Qiaoyan Wang James Warren Georgina L Warry Xuehong Wei Anthony West Siobhan L Whitehead Mathew N Whiteley Jane E Wilkinson David L Willey Gabrielle Williams Leanne Williams Angela Williamson Helen Williamson Laurens Wilming Rebecca L Woodmansey Paul W Wray Jennifer Yen Jingkun Zhang Jianling Zhou Huda Zoghbi Sara Zorilla David Buck Richard Reinhardt Annemarie Poustka André Rosenthal Hans Lehrach Alfons Meindl Patrick J Minx Ladeana W Hillier Huntington F Willard Richard K Wilson Robert H Waterston Catherine M Rice Mark Vaudin Alan Coulson David L Nelson George Weinstock John E Sulston Richard Durbin Tim Hubbard Richard A Gibbs Stephan Beck Jane Rogers David R Bentley

Nature 2005 Mar;434(7031):325-37

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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March 2005

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking.

EMBO J 2005 Mar 10;24(6):1122-33. Epub 2005 Mar 10.

Cell Biology and Cell Biophysics Programme, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.

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March 2005

arrayMagic: two-colour cDNA microarray quality control and preprocessing.

Bioinformatics 2005 Feb 28;21(4):554-6. Epub 2004 Sep 28.

Department of Molecular Genome Analysis, German Cancer Research Center INF 580, Heidelberg, 69120, Germany.

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February 2005

Gene expression in kidney cancer is associated with cytogenetic abnormalities, metastasis formation, and patient survival.

Clin Cancer Res 2005 Jan;11(2 Pt 1):646-55

Division of Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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January 2005

Recent advances in transcription profiling of human cancer.

Curr Opin Mol Ther 2004 Dec;6(6):593-9

German Cancer Research Center, Division of Molecular Genome Analysis, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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December 2004

High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic.

Genome Res 2004 Oct;14(10A):1948-56

Cell Biology and Biophysics Programme, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.

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October 2004

The German cDNA network: cDNAs, functional genomics and proteomics.

J Struct Funct Genomics 2003 ;4(2-3):87-96

Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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July 2004

Integrative annotation of 21,037 human genes validated by full-length cDNA clones.

Authors:
Tadashi Imanishi Takeshi Itoh Yutaka Suzuki Claire O'Donovan Satoshi Fukuchi Kanako O Koyanagi Roberto A Barrero Takuro Tamura Yumi Yamaguchi-Kabata Motohiko Tanino Kei Yura Satoru Miyazaki Kazuho Ikeo Keiichi Homma Arek Kasprzyk Tetsuo Nishikawa Mika Hirakawa Jean Thierry-Mieg Danielle Thierry-Mieg Jennifer Ashurst Libin Jia Mitsuteru Nakao Michael A Thomas Nicola Mulder Youla Karavidopoulou Lihua Jin Sangsoo Kim Tomohiro Yasuda Boris Lenhard Eric Eveno Yoshiyuki Suzuki Chisato Yamasaki Jun-ichi Takeda Craig Gough Phillip Hilton Yasuyuki Fujii Hiroaki Sakai Susumu Tanaka Clara Amid Matthew Bellgard Maria de Fatima Bonaldo Hidemasa Bono Susan K Bromberg Anthony J Brookes Elspeth Bruford Piero Carninci Claude Chelala Christine Couillault Sandro J de Souza Marie-Anne Debily Marie-Dominique Devignes Inna Dubchak Toshinori Endo Anne Estreicher Eduardo Eyras Kaoru Fukami-Kobayashi Gopal R Gopinath Esther Graudens Yoonsoo Hahn Michael Han Ze-Guang Han Kousuke Hanada Hideki Hanaoka Erimi Harada Katsuyuki Hashimoto Ursula Hinz Momoki Hirai Teruyoshi Hishiki Ian Hopkinson Sandrine Imbeaud Hidetoshi Inoko Alexander Kanapin Yayoi Kaneko Takeya Kasukawa Janet Kelso Paul Kersey Reiko Kikuno Kouichi Kimura Bernhard Korn Vladimir Kuryshev Izabela Makalowska Takashi Makino Shuhei Mano Regine Mariage-Samson Jun Mashima Hideo Matsuda Hans-Werner Mewes Shinsei Minoshima Keiichi Nagai Hideki Nagasaki Naoki Nagata Rajni Nigam Osamu Ogasawara Osamu Ohara Masafumi Ohtsubo Norihiro Okada Toshihisa Okido Satoshi Oota Motonori Ota Toshio Ota Tetsuji Otsuki Dominique Piatier-Tonneau Annemarie Poustka Shuang-Xi Ren Naruya Saitou Katsunaga Sakai Shigetaka Sakamoto Ryuichi Sakate Ingo Schupp Florence Servant Stephen Sherry Rie Shiba Nobuyoshi Shimizu Mary Shimoyama Andrew J Simpson Bento Soares Charles Steward Makiko Suwa Mami Suzuki Aiko Takahashi Gen Tamiya Hiroshi Tanaka Todd Taylor Joseph D Terwilliger Per Unneberg Vamsi Veeramachaneni Shinya Watanabe Laurens Wilming Norikazu Yasuda Hyang-Sook Yoo Marvin Stodolsky Wojciech Makalowski Mitiko Go Kenta Nakai Toshihisa Takagi Minoru Kanehisa Yoshiyuki Sakaki John Quackenbush Yasushi Okazaki Yoshihide Hayashizaki Winston Hide Ranajit Chakraborty Ken Nishikawa Hideaki Sugawara Yoshio Tateno Zhu Chen Michio Oishi Peter Tonellato Rolf Apweiler Kousaku Okubo Lukas Wagner Stefan Wiemann Robert L Strausberg Takao Isogai Charles Auffray Nobuo Nomura Takashi Gojobori Sumio Sugano

PLoS Biol 2004 Jun 20;2(6):e162. Epub 2004 Apr 20.

Integrated Database Group, Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC393292PMC
June 2004

SMART amplification combined with cDNA size fractionation in order to obtain large full-length clones.

BMC Genomics 2004 Jun 15;5(1):36. Epub 2004 Jun 15.

Department of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC436056PMC
June 2004

CDNAs for functional genomics and proteomics: the German Consortium.

C R Biol 2003 Oct-Nov;326(10-11):1003-9

Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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May 2004

High-throughput protein analysis integrating bioinformatics and experimental assays.

Nucleic Acids Res 2004 3;32(2):742-8. Epub 2004 Feb 3.

Division of Molecular Biophysics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373366PMC
April 2004

Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments.

BMC Genomics 2004 Apr 30;5(1):29. Epub 2004 Apr 30.

Department of Molecular Genome Analysis, German Cancer Research Centre, Heidelberg 69120, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419340PMC
April 2004

Thioredoxin, a regulator of gene expression.

Oncogene 2004 Mar;23(12):2146-52

Institut für Biochemie, Freie Universität Berlin, Thielallee 63, Berlin D-14195, Germany.

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March 2004

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system.

Nucleic Acids Res 2004 Jan;32(Database issue):D505-8

German Cancer Research Center (DKFZ), Division of Molecular Genome Analysis, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC314201PMC
January 2004

A microscope-based screening platform for large-scale functional protein analysis in intact cells.

FEBS Lett 2003 Nov;554(3):394-8

Cell Biology and Cell Biophysics Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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November 2003

Candidate genes for cross-resistance against DNA-damaging drugs.

Cancer Res 2002 Nov;62(22):6698-705

Department of Molecular Genome Analysis, Deutsches Krebsforschungszentrum, D-69120 Heidelberg, Germany.

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November 2002

Mutation analysis of the coding sequence of the MECP2 gene in infantile autism.

Hum Genet 2002 Oct 14;111(4-5):305-9. Epub 2002 Aug 14.

Department of Molecular Genome Analysis (H0600), Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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October 2002

Rare mutations of the DMBT1 gene in human astrocytic gliomas.

Oncogene 2002 Aug;21(38):5956-9

Institute for Neuropathology, Charité Humboldt University, D-13353 Berlin, Germany.

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August 2002