Publications by authors named "Anne-Claude Gingras"

100Publications

A High-Density Human Mitochondrial Proximity Interaction Network.

Cell Metab 2020 Sep;32(3):479-497.e9

Montreal Neurological Institute, McGill University, Montreal, QC, Canada; Department of Human Genetics, McGill University, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2020.07.017DOI Listing
September 2020

Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation.

Nucleic Acids Res 2020 08;48(14):7924-7943

Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1093/nar/gkaa592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430652PMC
August 2020

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

J Proteome Res 2020 Aug 20;19(8):3554-3561. Epub 2020 Jul 20.

Princess Margaret Cancer Centre, University Health Network, University of Toronto, 101 College Street, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1021/acs.jproteome.0c00117DOI Listing
August 2020

Virtual Issue: Technological Innovations.

Mol Cell Proteomics 2020 04 17;19(4):572-573. Epub 2020 Mar 17.

University of California, San Francisco, CA.

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http://dx.doi.org/10.1074/mcp.E120.002042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124464PMC
April 2020

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling.

Science 2020 03;367(6483):1264-1269

Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1126/science.aax0902DOI Listing
March 2020

Proximity Dependent Biotinylation: Key Enzymes and Adaptation to Proteomics Approaches.

Mol Cell Proteomics 2020 05 3;19(5):757-773. Epub 2020 Mar 3.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada

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http://dx.doi.org/10.1074/mcp.R120.001941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196579PMC
May 2020

Connecting proteins: shareable tools for reproducible interaction mapping.

Biochem Cell Biol 2020 06 5;98(3):309-313. Epub 2019 Nov 5.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 600 University Avenue, Room 992, Toronto, ON M5G 1X5, Canada.

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http://dx.doi.org/10.1139/bcb-2019-0285DOI Listing
June 2020

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

Mol Cell Proteomics 2020 01 2;19(1):50-64. Epub 2019 Nov 2.

Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada

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http://dx.doi.org/10.1074/mcp.RA119.001811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944238PMC
January 2020

Properties of Stress Granule and P-Body Proteomes.

Mol Cell 2019 10;76(2):286-294

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.09.014DOI Listing
October 2019

Gene Information eXtension (GIX): effortless retrieval of gene product information on any website.

Nat Methods 2019 08;16(8):665-666

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41592-019-0477-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669099PMC
August 2019

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

Structure 2019 06 2;27(6):1000-1012.e6. Epub 2019 May 2.

Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.str.2019.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551266PMC
June 2019

Getting to know the neighborhood: using proximity-dependent biotinylation to characterize protein complexes and map organelles.

Curr Opin Chem Biol 2019 02 17;48:44-54. Epub 2018 Nov 17.

Princess Margaret Cancer Centre, University Health Network, and Department of Medical Biophysics, University of Toronto, 101 College Street, 9-701A, Toronto, ON, M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.cbpa.2018.10.017DOI Listing
February 2019

A Versatile Lentiviral Delivery Toolkit for Proximity-dependent Biotinylation in Diverse Cell Types.

Mol Cell Proteomics 2018 11 10;17(11):2256-2269. Epub 2018 Jul 10.

From the ‡Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.TIR118.00090
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http://dx.doi.org/10.1074/mcp.TIR118.000902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210231PMC
November 2018

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.

Structure 2018 08 5;26(8):1101-1115.e6. Epub 2018 Jul 5.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 600 University Avenue, Toronto, ON M5G 1X5, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087429PMC
August 2018

In planta proximity dependent biotin identification (BioID).

Sci Rep 2018 06 15;8(1):9212. Epub 2018 Jun 15.

Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, M5S 3B2, Canada.

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http://dx.doi.org/10.1038/s41598-018-27500-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004002PMC
June 2018

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

J Mol Biol 2018 07 17;430(14):2153-2163. Epub 2018 May 17.

Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005816PMC
July 2018

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.

Cell Rep 2018 03;22(12):3191-3205

Goodman Cancer Research Centre, McGill University, Montreal, QC H3G 0B1, Canada; Department of Biochemistry, McGill University, Montreal, QC H2W 1S6, Canada; Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873529PMC
March 2018

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

Mol Cell 2018 02 25;69(3):517-532.e11. Epub 2018 Jan 25.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.12.020DOI Listing
February 2018

Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2.

Microb Cell 2017 Oct 2;4(10):342-361. Epub 2017 Oct 2.

Aberdeen Fungal Group, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.15698/mic2017.10.594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657825PMC
October 2017

AIRE is a critical spindle-associated protein in embryonic stem cells.

Elife 2017 07 25;6. Epub 2017 Jul 25.

Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.7554/eLife.28131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560860PMC
July 2017

Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing.

Cell 2017 Jul;170(2):324-339.e23

Donnelly Centre, University of Toronto, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.06.037DOI Listing
July 2017

ProHits-viz: a suite of web tools for visualizing interaction proteomics data.

Nat Methods 2017 06;14(7):645-646

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nmeth.4330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831326PMC
June 2017

CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme.

Open Biol 2017 06;7(6)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5

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http://dx.doi.org/10.1098/rsob.170114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493781PMC
June 2017

CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization.

J Proteome Res 2017 07 5;16(7):2645-2652. Epub 2017 Jun 5.

Institute for Research in Immunology and Cancer, Université de Montréal , Montréal, Québec H3C 3J7, Canada.

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http://dx.doi.org/10.1021/acs.jproteome.7b00205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994346PMC
July 2017

MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.

Mol Cell Proteomics 2017 06 3;16(6):1098-1110. Epub 2017 Apr 3.

From the ‡Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada, M5G 1X5,

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http://dx.doi.org/10.1074/mcp.M116.065490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461540PMC
June 2017

Regulation of Protein Interactions by ps ne inder (MOB1) Phosphorylation.

Mol Cell Proteomics 2017 06 3;16(6):1111-1125. Epub 2017 Apr 3.

From the ‡Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada, M5G 1X5;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M117.068130
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http://dx.doi.org/10.1074/mcp.M117.068130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461541PMC
June 2017

CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity.

Curr Biol 2017 Mar 9;27(6):868-876. Epub 2017 Mar 9.

Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.02.028DOI Listing
March 2017

Parallel Exploration of Interaction Space by BioID and Affinity Purification Coupled to Mass Spectrometry.

Methods Mol Biol 2017 ;1550:115-136

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada.

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http://dx.doi.org/10.1007/978-1-4939-6747-6_10DOI Listing
February 2018

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

Mol Cell 2017 Jan 5;65(2):347-360. Epub 2017 Jan 5.

Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663465PMC
January 2017

A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.

EMBO Rep 2017 01 14;18(1):28-38. Epub 2016 Dec 14.

Department of Human Genetics, Montreal Neurological Institute, McGill University, Montreal, QC, Canada

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http://dx.doi.org/10.15252/embr.201643391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210091PMC
January 2017

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.

Cell Rep 2016 12;17(10):2724-2737

Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building Roosevelt Drive, Oxford OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177622PMC
December 2016

Activation of Mitochondrial Protein Phosphatase SLP2 by MIA40 Regulates Seed Germination.

Plant Physiol 2017 02 6;173(2):956-969. Epub 2016 Dec 6.

Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada (R.G.U., A.-M.L.,L.-Y.T., N.A.S., E.Y., M.A.S., G.B.G.M.);

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http://dx.doi.org/10.1104/pp.16.01641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291043PMC
February 2017

Acetylation of PCNA Sliding Surface by Eco1 Promotes Genome Stability through Homologous Recombination.

Mol Cell 2017 Jan 1;65(1):78-90. Epub 2016 Dec 1.

St-Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Centre de Recherche du CHU de Québec-Axe Oncologie, Quebec City, QC G1R 3S3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.10.033DOI Listing
January 2017

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

Cell Rep 2016 11;17(9):2488-2501

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.078DOI Listing
November 2016

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.

Cancer Res 2017 01 21;77(2):434-447. Epub 2016 Nov 21.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2060DOI Listing
January 2017

Data Independent Acquisition analysis in ProHits 4.0.

J Proteomics 2016 10 29;149:64-68. Epub 2016 Apr 29.

Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079801PMC
http://dx.doi.org/10.1016/j.jprot.2016.04.042DOI Listing
October 2016

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

J Cell Sci 2016 09 12;129(18):3396-411. Epub 2016 Aug 12.

Center for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5 Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.188417
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http://dx.doi.org/10.1242/jcs.188417DOI Listing
September 2016

Proteomics approaches to decipher new signaling pathways.

Curr Opin Struct Biol 2016 12 22;41:128-134. Epub 2016 Jul 22.

Lunenfeld-Tanenbaum Research Institute, Toronto, Canada; Dept. of Molecular Genetics, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.sbi.2016.07.008DOI Listing
December 2016

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.

Mol Cell 2016 05;62(3):409-421

St. Patrick Research Group in Basic Oncology, Laval University Cancer Research Center, Quebec City, QC G1R 3S3, Canada; Centre Hospitalier Universitaire de Québec Research Center and School of Medicine, Laval University, Quebec City, QC G1V 4G2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887106PMC
May 2016

SAINTq: Scoring protein-protein interactions in affinity purification - mass spectrometry experiments with fragment or peptide intensity data.

Proteomics 2016 08 27;16(15-16):2238-45. Epub 2016 May 27.

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.

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http://dx.doi.org/10.1002/pmic.201500499DOI Listing
August 2016

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.

Elife 2016 Jan 19;5:e11394. Epub 2016 Jan 19.

Department of Medicine, University of California, San Diego, San Diego, United States.

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http://dx.doi.org/10.7554/eLife.11394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733052PMC
January 2016

HELB Is a Feedback Inhibitor of DNA End Resection.

Mol Cell 2016 Feb 7;61(3):405-418. Epub 2016 Jan 7.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, ON M5S 1A8, Canada. Electronic address:

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http://www.cell.com/molecular-cell/pdf/S1097-2765(15)00947-8
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http://linkinghub.elsevier.com/retrieve/pii/S109727651500947
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http://dx.doi.org/10.1016/j.molcel.2015.12.013DOI Listing
February 2016

MSPLIT-DIA: sensitive peptide identification for data-independent acquisition.

Nat Methods 2015 Dec;12(12):1106-8

Center for Computational Mass Spectrometry, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nmeth.3655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857761PMC
December 2015