Biochemical marker discovery, testing and evaluation for facilitating OA drug discovery and development.
Drug Discov Today 2018 Feb 14;23(2):349-358. Epub 2017 Oct 14.
Department of Veterinary Pre-Clinical Sciences, School of Veterinary Medicine, Faculty of Health and Medical Sciences University of Surrey, Guildford, GU2 7AL, UK; Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, Queen's Medical Centre, Nottingham, NG7 2UH, UK; Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Santariskiu 5, 08661, Vilnius, Republic of Lithuania. Electronic address:

Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients.
Pain 2017 Jul;158(7):1254-1263
aNordic Bioscience Biomarkers & Research, Nordic Bioscience A/S, Herlev, Denmark bDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark cNeuroscience, Innovative Medicines and Early Development, AstraZeneca, Cambridge, United Kingdom dDepartment of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Uppsala, Sweden eQuantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA fDepartment of Radiology, Hôpital Saint-Antoine, University Paris VI, Paris, France.

Clinical Drug Development Using Dynamic Biomarkers to Enable Personalized Health Care in COPD.
Chest 2015 Jul;148(1):16-23
Respiratory and Allergy Research Group, Manchester Academic Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, England.

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis.
Am J Physiol Gastrointest Liver Physiol 2015 May 12;308(10):G807-30. Epub 2015 Mar 12.
Institute of Translational Immunology and Research Center for Immunotherapy, University of Mainz Medical Center, Mainz, Germany; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

The distribution pattern of critically short telomeres in human osteoarthritic knees.
Arthritis Res Ther 2012 Jan 18;14(1):R12. Epub 2012 Jan 18.
Department of Clinical Cell Biology, Vejle/Lillebaelt Hospital, Institute of Regional Health Research, University of Southern Denmark, Kabbeltoft 25, 7100 Vejle, Denmark.

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women.
Biomarkers 2015 5;20(8):557-64. Epub 2016 Feb 5.
a Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford , Oxford , UK .