Publications by authors named "Anne Spurkland"

49Publications

Adaptor proteins: Flexible and dynamic modulators of immune cell signaling.

Scand J Immunol 2020 Jul 31:e12951. Epub 2020 Jul 31.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1111/sji.12951DOI Listing
July 2020

A simple and efficient workflow for generation of knock-in mutations in Jurkat T cells using CRISPR/Cas9.

Scand J Immunol 2020 Apr 14;91(4):e12862. Epub 2020 Jan 14.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1111/sji.12862DOI Listing
April 2020

Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd.

Sci Rep 2018 09 6;8(1):13319. Epub 2018 Sep 6.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1038/s41598-018-31510-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127336PMC
September 2018

In vitro analysis of antigen induced T cell-monocyte conjugates by imaging flow cytometry.

J Immunol Methods 2018 09 4;460:93-100. Epub 2018 Jul 4.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2018.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462223PMC
September 2018

The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation.

Sci Signal 2016 07 19;9(437):ra72. Epub 2016 Jul 19.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsv 20, Uppsala 75185, Sweden.

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http://dx.doi.org/10.1126/scisignal.aad9256DOI Listing
July 2016

T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells.

Cell Commun Signal 2015 Jul 11;13:31. Epub 2015 Jul 11.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, 0317, Norway.

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http://dx.doi.org/10.1186/s12964-015-0109-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499191PMC
July 2015

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.

J Immunol 2015 May 30;194(9):4518-27. Epub 2015 Mar 30.

Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, 141 86 Stockholm, Sweden; K.G. Jebsen Center for Cancer Immunotherapy, Institute of Clinical Medicine, University of Oslo, 0316 Oslo, Norway; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, 0310 Oslo, Norway;

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http://dx.doi.org/10.4049/jimmunol.1401972DOI Listing
May 2015

Retinoic acid enhances the levels of IL-10 in TLR-stimulated B cells from patients with relapsing-remitting multiple sclerosis.

J Neuroimmunol 2015 Jan 24;278:11-8. Epub 2014 Nov 24.

Department of Biochemistry, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01655728140098
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http://dx.doi.org/10.1016/j.jneuroim.2014.11.019DOI Listing
January 2015

The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.

Sci Signal 2014 Dec 9;7(355):ra118. Epub 2014 Dec 9.

Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.

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http://dx.doi.org/10.1126/scisignal.2005384DOI Listing
December 2014

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

B-cell tolerance to the B-cell receptor variable regions.

Eur J Immunol 2013 Oct 19;43(10):2577-87. Epub 2013 Jul 19.

Centre for Immune Regulation, Institute of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

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http://dx.doi.org/10.1002/eji.201243203DOI Listing
October 2013

[New gene map for multiple sclerosis].

Tidsskr Nor Laegeforen 2011 Nov;131(21):2126-30

Nevrologisk avdeling, Oslo universitetssykehus, Ullevål, Norway.

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http://dx.doi.org/10.4045/tidsskr.10.0823DOI Listing
November 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Expression of the T-cell-specific adapter protein in oral epithelium.

Eur J Oral Sci 2010 Apr;118(2):159-67

Department of Oral Biology, Faculty of Dentistry, University of Oslo, Norway.

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http://dx.doi.org/10.1111/j.1600-0722.2010.00719.xDOI Listing
April 2010

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

Ann Neurol 2009 Jun;65(6):658-66

Department of Neurology, Faculty Division Ullevål, Oslo University Hospital, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1002/ana.21695DOI Listing
June 2009

Genetic and molecular approaches to the immunopathogenesis of multiple sclerosis: an update.

Curr Mol Med 2009 Jun;9(5):591-611

Institute of Immunology, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.2174/156652409788488793DOI Listing
June 2009

The SH2D2A gene and susceptibility to multiple sclerosis.

J Neuroimmunol 2008 Jul 12;197(2):152-8. Epub 2008 Jun 12.

Department of Neurology, University of Oslo, Oslo, Norway; Institute of Immunology, Rikshospitalet University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1016/j.jneuroim.2008.04.037DOI Listing
July 2008

Modulation of Lck function through multisite docking to T cell-specific adapter protein.

J Biol Chem 2008 Aug 9;283(32):21909-19. Epub 2008 Jun 9.

Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, Box 1105, Blindern, N-0317 Oslo, Norway.

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http://dx.doi.org/10.1074/jbc.M800871200DOI Listing
August 2008

Mapping genes and pathways in autoimmune disease.

Trends Immunol 2006 Jul 5;27(7):336-42. Epub 2006 Jun 5.

Institute of Basic Medical Sciences, University of Oslo, Rikshospitalet University Hospital, Oslo N-0317, Norway.

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http://dx.doi.org/10.1016/j.it.2006.05.008DOI Listing
July 2006

No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis.

Scand J Gastroenterol 2006 May;41(5):586-91

Medical Department, Rikshospitalet University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1080/00365520500377870DOI Listing
May 2006

Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients.

J Neuroimmunol 2005 Sep;166(1-2):197-201

Institute of Immunology, University of Oslo and Rikshospitalet University Hospital, 00207 Oslo, Norway.

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http://dx.doi.org/10.1016/j.jneuroim.2005.06.002DOI Listing
September 2005

The C terminus of T cell-specific adapter protein (TSAd) is necessary for TSAd-mediated inhibition of Lck activity.

Eur J Immunol 2005 May;35(5):1612-20

Institute of Basic Medical Sciences, Department of Anatomy, University of Oslo, Blindern, Oslo, Norway.

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http://dx.doi.org/10.1002/eji.200425638DOI Listing
May 2005

Microchimerism in immune competent patients related to the leukocyte content of transfused red blood cell concentrates.

Transfus Apher Sci 2004 Dec;31(3):173-80

Institute of Immunology, Rikshospitalet University Hospital, Oslo NO-0023, Norway; Blood Bank, Asker and Baerum Hospital, Rud NO-1309, Norway.

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http://dx.doi.org/10.1016/j.transci.2004.07.012DOI Listing
December 2004

cDNA cloning of a rat orthologue of SH2D2A encoding T-cell-specific adaptor protein (TSAd): expression in T and NK cells.

Immunogenetics 2004 Aug 5;56(5):338-42. Epub 2004 Aug 5.

Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, Blindern, P.O. Box 1105, 0317, Oslo, Norway.

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http://link.springer.com/10.1007/s00251-004-0695-9
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http://dx.doi.org/10.1007/s00251-004-0695-9DOI Listing
August 2004

[Genetic variation--useful information for everybody?].

Tidsskr Nor Laegeforen 2002 Mar;122(8):826-7

Immunologisk institutt Rikshospitalet 0027 Oslo.

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March 2002