Anne Schultheis

Anne Schultheis

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Anne Schultheis

Anne Schultheis

Publications by authors named "Anne Schultheis"

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Comparison of in Situ and Extraction-Based Methods for the Detection of ROS1 Rearrangements in Solid Tumors.

J Mol Diagn 2019 Aug 2. Epub 2019 Aug 2.

Institute of Pathology, University Hospital Cologne, Cologne, Germany; Network Genomic Medicine, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.06.006DOI Listing
August 2019

Clinical impact of PD-L1 and PD-1 expression in squamous cell cancer of the vulva.

J Cancer Res Clin Oncol 2019 Jun 10;145(6):1651-1660. Epub 2019 Apr 10.

Department of Pathology, University Hospital of Cologne, Institute of Pathology, Kerpener Str. 62, 50937, Cologne, Germany.

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http://dx.doi.org/10.1007/s00432-019-02915-1DOI Listing
June 2019

[Excision and tectonic covering of a vascular leiomyoma of the ciliary body with large anterior staphyloma using scleral patch graft].

Ophthalmologe 2019 Jun 14. Epub 2019 Jun 14.

Zentrum für Augenheilkunde, Universität zu Köln, Kerpener Str. 62, 50924, Köln, Deutschland.

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http://dx.doi.org/10.1007/s00347-019-0919-xDOI Listing
June 2019

Combined Targeted Resequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for Poly(ADP-Ribose) Polymerase 1 Inhibitor Sensitivity Testing.

J Mol Diagn 2019 Mar 19;21(2):198-213. Epub 2018 Dec 19.

Department of Translational Epigenetics and Tumor Genetics, University Hospital Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University Hospital Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2018.10.007DOI Listing
March 2019

Block Excision of Iridociliary Tumors Enables Molecular Profiling and Immune Vaccination.

Ophthalmology 2017 02 27;124(2):268-270. Epub 2016 Oct 27.

Department of Ophthalmology, University of Cologne, Cologne, Germany; Center for Integrated Oncology (CIO) Cologne-Bonn, Cologne, Germany.

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http://dx.doi.org/10.1016/j.ophtha.2016.09.011DOI Listing
February 2017

Mixed Mesonephric Adenocarcinoma and High-grade Neuroendocrine Carcinoma of the Uterine Cervix: Case Description of a Previously Unreported Entity With Insights Into Its Molecular Pathogenesis.

Int J Gynecol Pathol 2017 Jan;36(1):76-89

Department of Pathology (M.S.C., A.M.S., C.H., L.W., D.F.D, B.W., M.H., K.J.P.)Department of Surgery, Gynecologic Oncology Service (G.G.)Department of Medicine, Memorial Sloan Kettering Cancer Center (S.M.L.)Weill Medical College - Cornell University, New York, New York (G.G., S.M.L.).

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http://dx.doi.org/10.1097/PGP.0000000000000306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500437PMC
January 2017

The impact of sequencing on diagnosis and treatment of malignant melanoma.

Expert Rev Mol Diagn 2016 19;16(4):423-33. Epub 2016 Feb 19.

a Institute of Pathology , University Hospital Cologne , Cologne , Germany.

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http://dx.doi.org/10.1586/14737159.2016.1147958DOI Listing
December 2016

TP53 Mutational Spectrum in Endometrioid and Serous Endometrial Cancers.

Int J Gynecol Pathol 2016 Jul;35(4):289-300

Department of Pathology (A.M.S., L.G.M., M.R.D.F., S.P., C.K.Y.N., Y.R.H., J.S.R.-F., R.A.S., B.W.) Human Oncology and Pathogenesis Program (J.S.R.-F.), Memorial Sloan Kettering Cancer Center, New York, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087968PMC
http://dx.doi.org/10.1097/PGP.0000000000000243DOI Listing
July 2016

Massively Parallel Sequencing-Based Clonality Analysis of Synchronous Endometrioid Endometrial and Ovarian Carcinomas.

J Natl Cancer Inst 2016 Jun 1;108(6):djv427. Epub 2016 Feb 1.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY (AMS, CKYN, MRDF, SP, GSM, RAS, RSL, JSRF, BW); Department of Pathology, Hospital Universitario Arnau de Vilanova, University of Lleida, Lleida, Spain (SG, XMG); Department of Pathology, Hospital Universitario Ramón y Cajal, Madrid, Spain (BPM, JCP); Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY (AV, KHH); Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY (JSRF).

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http://jnci.oxfordjournals.org/content/108/6/djv427.full.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv42
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http://dx.doi.org/10.1093/jnci/djv427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909128PMC
June 2016

PD-L1 expression in non-small cell lung cancer: Correlations with genetic alterations.

Oncoimmunology 2016 May 16;5(5):e1131379. Epub 2016 Mar 16.

Center for Integrated Oncology Köln Bonn, Cologne, Germany; Lung Cancer Group Cologne, Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1080/2162402X.2015.1131379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910698PMC
May 2016

Analysis of topographical distribution of prostate cancer and related pathological findings in prostatectomy specimens using cMDX document architecture.

J Biomed Inform 2016 Feb 17;59:240-7. Epub 2015 Dec 17.

Dept. of Urology, University Hospital of Cologne, Kerpener Straße 62, D-50937 Cologne, Germany.

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http://dx.doi.org/10.1016/j.jbi.2015.12.009DOI Listing
February 2016

Spatial Tumor Heterogeneity in Lung Cancer with Acquired Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance: Targeting High-Level MET-Amplification and EGFR T790M Mutation Occurring at Different Sites in the Same Patient.

J Thorac Oncol 2015 Jun;10(6):e40-3

*Lung Cancer Group Cologne, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; †Center for Integrated Oncology Köln Bonn, Institute of Pathology, University Hospital of Cologne, Cologne, Germany; ‡Department of Translational Genomics, Center for Integrated Oncology Köln Bonn, University of Cologne, Cologne, Germany; §Lung Cancer Group Cologne, Department I of Internal Medicine, Center for Integrated Oncology Köln Bonn, University Hospital of Cologne, Cologne, Germany; ‖Department I of Internal Medicine, Center for Integrated Oncology Köln Bonn, University Hospital of Cologne, Cologne, Germany; ¶Center for Integrated Oncology Köln Bonn, Institute of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany; and #Institute of Hematopathology Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000503DOI Listing
June 2015

The birth of an adenoid cystic carcinoma.

Int J Surg Pathol 2015 Feb 3;23(1):26-7. Epub 2014 Sep 3.

Memorial Sloan Kettering Cancer Center, New York, NY, USA

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http://journals.sagepub.com/doi/10.1177/1066896914548795
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http://dx.doi.org/10.1177/1066896914548795DOI Listing
February 2015

MET amplification status in therapy-naïve adeno- and squamous cell carcinomas of the lung.

Clin Cancer Res 2015 Feb 9;21(4):907-15. Epub 2014 Dec 9.

Institute of Pathology, University Hospital Cologne, Cologne, Germany. Center for Integrated Oncology, University Hospital Cologne, Cologne, Germany. Targos Molecular Pathology, Kassel, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0450DOI Listing
February 2015

PD-L1 expression in small cell neuroendocrine carcinomas.

Eur J Cancer 2015 Feb 9;51(3):421-6. Epub 2015 Jan 9.

Institute of Pathology, University Hospital Cologne, Cologne, Germany; Center for Integrated Oncology (CIO) Cologne/Bonn, Germany.

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http://dx.doi.org/10.1016/j.ejca.2014.12.006DOI Listing
February 2015

Breast cancer genomics from microarrays to massively parallel sequencing: paradigms and new insights.

J Natl Cancer Inst 2015 Feb 23;107(5). Epub 2015 Feb 23.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY (CKYN, AMS, BW, JSRF); Department of Medical Oncology, SIRIC, Institut Curie, Paris, France (FCB); Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY (JSRF).

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http://dx.doi.org/10.1093/jnci/djv015DOI Listing
February 2015

Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy.

Case Rep Oncol Med 2014 19;2014:860532. Epub 2014 May 19.

Institute of Pathology, University Hospital Cologne, Kerpener Straße 62, 50924 Cologne, Germany.

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http://dx.doi.org/10.1155/2014/860532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052146PMC
June 2014

Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer.

Mod Pathol 2014 Feb 26;27(2):214-21. Epub 2013 Jul 26.

1] Institute of Pathology, University Hospital Cologne, Cologne, Germany [2] Center for Integrated Oncology Cologne/Bonn, Cologne, Germany [3] Institute of Pathology, University Hospital Göttingen, Göttingen, Germany.

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http://jco.ascopubs.org/content/31/6/731.full.pdf
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http://www.nature.com/doifinder/10.1038/modpathol.2013.141
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http://dx.doi.org/10.1038/modpathol.2013.141DOI Listing
February 2014

Strong ERG Positivity in Papillary Intralymphatic Angioendothelioma of the Testis of a 24-Year-Old Male: A Case Report.

Case Rep Pathol 2013 31;2013:531479. Epub 2013 Mar 31.

Institute of Pathology, University of Cologne Medical Center, 50937 Cologne, Germany.

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http://dx.doi.org/10.1155/2013/531479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626176PMC
April 2013

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.

J Clin Invest 2009 Oct 8;119(10):3011-23. Epub 2009 Sep 8.

Centre for Cancer and Inflammation, Institute of Cancer, Barts and The London School of Medicine and Dentistry,Queen Mary University of London, Charterhouse Square, London, United Kingdom.

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http://dx.doi.org/10.1172/JCI39065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752076PMC
October 2009

Polymorphisms in interleukin 1 beta and interleukin 1 receptor antagonist associated with tumor recurrence in stage II colon cancer.

Pharmacogenet Genomics 2009 Feb;19(2):95-102

Division of Medical Oncology, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32831a9ad1DOI Listing
February 2009

FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

J Clin Oncol 2007 Aug;25(24):3712-8

Division of Medical Oncology, Department of Pathology, University of Southern California, Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1200/JCO.2006.08.8021DOI Listing
August 2007

ABCB1, SLCO1B1 and UGT1A1 gene polymorphisms are associated with toxicity in metastatic colorectal cancer patients treated with first-line irinotecan.

Drug Metab Lett 2007 Jan;1(1):23-30

Divison of Medical Oncology, University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90033, USA.

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January 2007

Molecular determinants of irinotecan efficacy.

Int J Cancer 2006 Nov;119(10):2435-42

Divison of Medical Oncology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA.

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http://dx.doi.org/10.1002/ijc.22129DOI Listing
November 2006

Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab.

Pharmacogenet Genomics 2006 Jul;16(7):475-83

Division of Medical Oncology, Department of Preventive Medicine, University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1097/01.fpc.0000220562.67595.a5DOI Listing
July 2006