Anne Robinson

Anne Robinson

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Anne Robinson

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Membrane cholesterol depletion reduces downstream signaling activity of the adenosine A receptor.

Biochim Biophys Acta Biomembr 2019 Apr 8;1861(4):760-767. Epub 2019 Jan 8.

Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, LA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383678PMC
April 2019

The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release.

J Biol Chem 2018 12 4;293(49):19137-19147. Epub 2018 Oct 4.

From the Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706 and

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http://dx.doi.org/10.1074/jbc.RA118.005430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295725PMC
December 2018

The occasional treatment of opioid use disorder.

Can J Rural Med Spring 2017;22(2):69-75

Anishnaabe Bimaadiziwin Research Program, Sioux Lookout, Ont.

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November 2018

Sixty seconds on . . . reverse mentoring.

Authors:
Anne Robinson

BMJ 2018 Nov 20;363:k4887. Epub 2018 Nov 20.

London, UK.

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http://dx.doi.org/10.1136/bmj.k4887DOI Listing
November 2018

Uropathogenic enterobacteria use the yersiniabactin metallophore system to acquire nickel.

J Biol Chem 2018 09 14;293(39):14953-14961. Epub 2018 Aug 14.

From the Division of Infectious Diseases, Department of Internal Medicine, Department of Molecular Microbiology, Center for Women's Infectious Diseases Research, Washington University, St. Louis, Missouri, 63110

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http://dx.doi.org/10.1074/jbc.RA118.004483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166729PMC
September 2018

Using Fluorescence Anisotropy for Ligand Binding Kinetics of Membrane Proteins.

Curr Protoc Protein Sci 2018 08 16;93(1):e63. Epub 2018 Jul 16.

Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana.

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http://doi.wiley.com/10.1002/cpps.63
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http://dx.doi.org/10.1002/cpps.63DOI Listing
August 2018

Biophysical characterization and molecular simulation of electrostatically driven self-association of a single-chain antibody.

Protein Sci 2018 07 3;27(7):1275-1285. Epub 2018 May 3.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, 19716.

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http://dx.doi.org/10.1002/pro.3415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032362PMC
July 2018

Lymphoma Risk and Overall Safety Profile of Adalimumab in Patients With Crohn's Disease With up to 6 Years of Follow-Up in the Pyramid Registry.

Am J Gastroenterol 2018 06 5;113(6):872-882. Epub 2018 Jun 5.

Academic Medical Center, Amsterdam, Netherlands. Medical university of Vienna, Vienna, Austria. Department of Medicine, university of Calgary, Calgary, Canada. Gastrointestinal Unit, Western General Hospital, Edinburgh, UK. AbbVie Inc., North Chicago, IL, USA. AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany. AbbVie Spain S.L.U., Madrid, Spain. Mayo Clinic, Division of Gastroenterology and Hepatology, Rochester, NY, USA.

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http://dx.doi.org/10.1038/s41395-018-0098-4DOI Listing
June 2018

The iron hand of uropathogenic Escherichia coli: the role of transition metal control in virulence.

Future Microbiol 2018 06 5;13:745-756. Epub 2018 Jun 5.

Division of Infectious Diseases, Department of Medicine, Department of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.2217/fmb-2017-0295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161082PMC
June 2018

A mass spectrometry based transport assay for studying EmrE transport of unlabeled substrates.

Anal Biochem 2018 05 17;549:130-135. Epub 2018 Mar 17.

Department of Biochemistry, University of Wisconsin at Madison, Madison, Wisconsin 53706, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2018.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938110PMC
May 2018

Clinical disease activity in the CALM study - Authors' reply.

Lancet 2018 04;391(10129):1482

Academic Medical Centre, Amsterdam, Netherlands.

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http://dx.doi.org/10.1016/S0140-6736(18)30775-XDOI Listing
April 2018

Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation.

Antibodies (Basel) 2017 Dec 21;7(1). Epub 2017 Dec 21.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA.

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http://dx.doi.org/10.3390/antib7010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698858PMC
December 2017

New free-exchange model of EmrE transport.

Proc Natl Acad Sci U S A 2017 11 7;114(47):E10083-E10091. Epub 2017 Nov 7.

Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1708671114
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http://dx.doi.org/10.1073/pnas.1708671114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703289PMC
November 2017

Copper import in Escherichia coli by the yersiniabactin metallophore system.

Nat Chem Biol 2017 Sep 24;13(9):1016-1021. Epub 2017 Jul 24.

Center for Women's Infectious Diseases Research, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nchembio.2441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562518PMC
September 2017

Driving Forces for Nonnative Protein Aggregation and Approaches to Predict Aggregation-Prone Regions.

Annu Rev Chem Biomol Eng 2017 06;8:139-159

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716; email:

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http://dx.doi.org/10.1146/annurev-chembioeng-060816-101404DOI Listing
June 2017

Long-term Efficacy and Safety of Adalimumab in Pediatric Patients with Crohn's Disease.

Inflamm Bowel Dis 2017 03;23(3):453-460

*Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; †Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York; ‡Pediatric Gastroenterology Unit, Department of Pediatrics, Universite Sorbonne Paris-Cite, Hospital Necker-Enfants Malades, Paris, France; §Department of Pediatric Gastroenterology, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands; ‖Pediatric Gastroenterology, Goryeb Children's Hospital/Atlantic Health, Morristown, New Jersey; ¶Division of Digestive Diseases, Connecticut Children's Medical Center, Hartford, Connecticut; **AbbVie Inc., North Chicago, Illinois; and ††AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.

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http://dx.doi.org/10.1097/MIB.0000000000001021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319394PMC
March 2017

AR Binding Kinetics in the Ligand Depletion Regime.

SLAS Discov 2017 02 27;22(2):166-175. Epub 2016 Sep 27.

1 Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA.

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http://dx.doi.org/10.1177/1087057116667256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896570PMC
February 2017

Cellular engineering for therapeutic protein production: product quality, host modification, and process improvement.

Biotechnol J 2017 Jan 9;12(1). Epub 2016 Dec 9.

Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, USA.

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http://dx.doi.org/10.1002/biot.201600105DOI Listing
January 2017

Crohn's Disease Activity and Concomitant Immunosuppressants Affect the Risk of Serious and Opportunistic Infections in Patients Treated With Adalimumab.

Am J Gastroenterol 2016 12 27;111(12):1806-1815. Epub 2016 Sep 27.

University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ajg.2016.433DOI Listing
December 2016

Interpreting Registrational Clinical Trials of Biological Therapies in Adults with Inflammatory Bowel Diseases.

Inflamm Bowel Dis 2016 11;22(11):2711-2723

*Department of Medicine, University of Calgary, Calgary, Alberta, Canada; †Division of Gastroenterology, University of California San Diego, La Jolla, California; ‡Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York; §Robarts Clinical Trials, Robarts Research Institute, Department of Medicine, University of Western Ontario, London, Ontario, Canada; ‖Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; ¶Department of Medicine, University Hospital Schleswig-Holstein, University of Kiel, Kiel, Germany; **INSERM Unité 954, Department of Gastroenterology, University of Lorraine, Nancy, France; ††Department of Gastroenterology, University Hospital Leuven, Leuven, Belgium; and ‡‡AbbVie Inc., North Chicago, Illinois.

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http://dx.doi.org/10.1097/MIB.0000000000000909DOI Listing
November 2016

Identifying a robust design space for glycosylation during monoclonal antibody production.

Biotechnol Prog 2016 09 1;32(5):1149-1162. Epub 2016 Jul 1.

Dept. of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, 19716.

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http://dx.doi.org/10.1002/btpr.2316DOI Listing
September 2016

Managing and characterizing monoclonal antibody glycosylation.

Authors:
Anne Robinson

Biotechnol Prog 2016 09;32(5):1089-1090

Catherine and Henry Boh Professor of Engineering and Chair of Chemical and Biomolecular Engineering, Tulane University, New Orleans, LA.

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http://dx.doi.org/10.1002/btpr.2387DOI Listing
September 2016

Weak protein interactions and pH- and temperature-dependent aggregation of human Fc1.

MAbs 2015 12;7(6):1072-83. Epub 2015 Aug 12.

d Department of Chemical and Biomolecular Engineering ; University of Delaware ; Newark , DE USA.

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http://dx.doi.org/10.1080/19420862.2015.1079678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966490PMC
August 2016

Impact of purification conditions and history on A2A adenosine receptor activity: The role of CHAPS and lipids.

Protein Expr Purif 2016 08 27;124:62-7. Epub 2016 May 27.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19711, United States; Department of Chemical and Biomolecular Engineering, 300 Lindy Boggs Laboratory, Tulane University, New Orleans, LA 70118, United States. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2016.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947529PMC
August 2016

Recombinant G protein-coupled receptor expression in Saccharomyces cerevisiae for protein characterization.

Methods Enzymol 2015 20;556:165-83. Epub 2015 Mar 20.

Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, Louisiana, USA; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2014.12.025DOI Listing
January 2016

Asymmetric protonation of EmrE.

J Gen Physiol 2015 Dec 16;146(6):445-61. Epub 2015 Nov 16.

Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110

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http://dx.doi.org/10.1085/jgp.201511404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664823PMC
December 2015

The evolving nature of narcotic use in northwestern Ontario.

Can J Rural Med 2014 ;19(4):158-60

Division of Clinical Sciences, Northern Ontario School of Medicine, Sioux Lookout, Ont.

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June 2015

Pharmacokinetics and exposure-efficacy relationship of adalimumab in pediatric patients with moderate to severe Crohn's disease: results from a randomized, multicenter, phase-3 study.

Inflamm Bowel Dis 2015 Apr;21(4):783-92

*Global Pharmaceutical Research and Development Division, AbbVie Inc., North Chicago, Illinois; †AbbVie Deutschland GmbH & Co KG, Ludwigshafen, Germany; ‡Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut; §Division of Gastroenterology and Nutrition, Goryeb Children's Hospital-Atlantic Health, Morristown, New Jersey; and ‖Service de gastroentérologie-hépatologie-nutrition pédiatriques, Hôpital Necker-Enfants Malades, Paris, France.

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http://dx.doi.org/10.1097/MIB.0000000000000327DOI Listing
April 2015

Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition.

Biochim Biophys Acta 2015 Feb 16;1848(2):603-14. Epub 2014 Nov 16.

Department of Chemical and Biomolecular Engineering, Tulane University, 300 Lindy Boggs Laboratory, 6823 St. Charles Ave, New Orleans, LA 70118, USA; Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2014.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565196PMC
February 2015

Protein folding and secretion: mechanistic insights advancing recombinant protein production in S. cerevisiae.

Curr Opin Biotechnol 2014 Dec 15;30:168-77. Epub 2014 Jul 15.

Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, LA 70118, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09581669140012
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http://dx.doi.org/10.1016/j.copbio.2014.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253588PMC
December 2014

Controllability analysis of protein glycosylation in CHO cells.

PLoS One 2014 3;9(2):e87973. Epub 2014 Feb 3.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087973PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912168PMC
October 2014

Identification of manipulated variables for a glycosylation control strategy.

Biotechnol Bioeng 2014 Oct 22;111(10):1957-70. Epub 2014 May 22.

Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, Delaware, 19716.

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http://dx.doi.org/10.1002/bit.25251DOI Listing
October 2014

Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis.

Lancet Infect Dis 2014 Aug 26;14(8):725-730. Epub 2014 Jun 26.

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; Rollins School of Public Health, Emory University, Atlanta, GA, USA. Electronic address:

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http://www.thelancet.com/pdfs/journals/laninf/PIIS1473-3099(
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http://linkinghub.elsevier.com/retrieve/pii/S147330991470767
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http://dx.doi.org/10.1016/S1473-3099(14)70767-4DOI Listing
August 2014

BiP clustering facilitates protein folding in the endoplasmic reticulum.

PLoS Comput Biol 2014 Jul 3;10(7):e1003675. Epub 2014 Jul 3.

Department of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081015PMC
July 2014

Conformational stability as a design target to control protein aggregation.

Protein Eng Des Sel 2014 May 9;27(5):157-67. Epub 2014 Apr 9.

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.1093/protein/gzu008DOI Listing
May 2014

Aggregates of α-chymotrypsinogen anneal to access more stable states.

Biotechnol Bioeng 2014 Apr 18;111(4):782-91. Epub 2013 Nov 18.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, 19716.

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http://dx.doi.org/10.1002/bit.25129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145008PMC
April 2014

Increased risk of malignancy with adalimumab combination therapy, compared with monotherapy, for Crohn's disease.

Gastroenterology 2014 Apr 18;146(4):941-9. Epub 2013 Dec 18.

University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1053/j.gastro.2013.12.025DOI Listing
April 2014

Competing aggregation pathways for monoclonal antibodies.

FEBS Lett 2014 Mar 12;588(6):936-41. Epub 2014 Feb 12.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19711, USA. Electronic address:

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http://doi.wiley.com/10.1016/j.febslet.2014.01.051
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http://dx.doi.org/10.1016/j.febslet.2014.01.051DOI Listing
March 2014

Exploring the use of adalimumab for patients with moderate Crohn's disease: subanalyses from induction and maintenance trials.

J Crohns Colitis 2013 Dec 18;7(12):958-67. Epub 2013 Mar 18.

Division of Gastroenterology, University of California San Diego, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.crohns.2013.02.016DOI Listing
December 2013

Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation.

J Phys Chem B 2013 Dec 10;117(50):16013-28. Epub 2013 Dec 10.

Department of Chemical and Biomolecular Engineering and Center for Molecular and Engineering Thermodynamics, University of Delaware , Newark, Delaware 19176, United States.

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http://pubs.acs.org/doi/10.1021/jp409300j
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http://dx.doi.org/10.1021/jp409300jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108795PMC
December 2013

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein.

Biochemistry 2013 Oct 27;52(40):6960-7. Epub 2013 Sep 27.

Department of Chemical and Biomolecular Engineering, University of Delaware , Newark, Delaware 19716, United States.

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http://dx.doi.org/10.1021/bi400866wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142060PMC
October 2013

Serum adalimumab concentration and clinical remission in patients with Crohn's disease.

Inflamm Bowel Dis 2013 May;19(6):1112-22

Biometrics Clinical Pharmacology and Pharmacometrics, AbbVie, AbbVie Inc., North Chicago, Illinois 60064, USA.

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http://dx.doi.org/10.1097/MIB.0b013e3182813242DOI Listing
May 2013

Analysis of ER resident proteins in Saccharomyces cerevisiae: implementation of H/KDEL retrieval sequences.

Traffic 2013 Apr 4;14(4):365-81. Epub 2013 Feb 4.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA.

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http://dx.doi.org/10.1111/tra.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594122PMC
April 2013

Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics.

Biotechnol J 2012 Dec;7(12):1451-61

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA.

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http://dx.doi.org/10.1002/biot.201200076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739047PMC
December 2012

An expression and purification system for the biosynthesis of adenosine receptor peptides for biophysical and structural characterization.

Protein Expr Purif 2012 Aug 19;84(2):224-35. Epub 2012 Jun 19.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, United States.

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http://dx.doi.org/10.1016/j.pep.2012.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572917PMC
August 2012

Recombinant protein expression and purification: a comprehensive review of affinity tags and microbial applications.

Biotechnol J 2012 May 10;7(5):620-34. Epub 2012 Jan 10.

Department of Chemical Engineering, University of Delaware, Newark, DE, USA.

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http://dx.doi.org/10.1002/biot.201100155DOI Listing
May 2012

Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast.

Yeast 2012 Mar 4;29(3-4):119-36. Epub 2012 Apr 4.

Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA.

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http://dx.doi.org/10.1002/yea.2895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371369PMC
March 2012

Therapeutic drug monitoring of biologics for inflammatory bowel disease.

Inflamm Bowel Dis 2012 Feb 21;18(2):349-58. Epub 2011 Oct 21.

Department of Hepatogastroenterology, Hôpital Claude Huriez, Centre Hospitalier Universitaire de Lille, Lille, France.

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http://dx.doi.org/10.1002/ibd.21831DOI Listing
February 2012

Adalimumab produces clinical remission and reduces extraintestinal manifestations in Crohn's disease: results from CARE.

Inflamm Bowel Dis 2012 Jan 23;18(1):1-9. Epub 2011 Feb 23.

Karolinska Institutet and Sophiahemmet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/ibd.21663DOI Listing
January 2012

Optimal management of cancer treatment-induced bone loss: considerations for elderly patients.

Drugs Aging 2011 Nov;28(11):867-83

Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, UK.

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http://dx.doi.org/10.2165/11595820-000000000-00000DOI Listing
November 2011

When meta-analysis misleads.

Am J Gastroenterol 2011 Nov;106(11):2043; author reply 2044

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http://dx.doi.org/10.1038/ajg.2011.245DOI Listing
November 2011

A practical, evidence-based guide to the use of adalimumab in Crohn's disease.

Curr Med Res Opin 2011 Sep 2;27(9):1803-13. Epub 2011 Aug 2.

University of Chicago Medical Center, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1185/03007995.2011.604672DOI Listing
September 2011

Decreased secretion and unfolded protein response upregulation.

Methods Enzymol 2011 ;491:235-60

Department of Chemical Engineering, University of Delaware, Newark, Delaware, USA.

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http://linkinghub.elsevier.com/retrieve/pii/B978012385928000
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http://dx.doi.org/10.1016/B978-0-12-385928-0.00014-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561176PMC
May 2011

New tools for breaking barriers to GPCR expression in E. coli.

Authors:
Anne Robinson

J Mol Biol 2011 May 21;408(4):597-8. Epub 2011 Mar 21.

University of Delaware, Newark, DE 19716, USA.

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http://dx.doi.org/10.1016/j.jmb.2011.03.032DOI Listing
May 2011

Solitary atrial metastases: a rare clinical challenge.

BMJ Case Rep 2011 Mar 29;2011. Epub 2011 Mar 29.

Department of Clinical Oncology, Southend University Hospital NHS Trust, Prittlewell, Southend-on-sea, UK.

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http://casereports.bmj.com/content/2011/bcr.11.2010.3506.ful
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http://casereports.bmj.com/cgi/doi/10.1136/bcr.11.2010.3506
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http://dx.doi.org/10.1136/bcr.11.2010.3506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070379PMC
March 2011

Dosage adjustment during long-term adalimumab treatment for Crohn's disease: clinical efficacy and pharmacoeconomics.

Inflamm Bowel Dis 2011 Jan;17(1):141-51

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/ibd.21328DOI Listing
January 2011

Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.

Biochemistry 2010 Nov;49(43):9181-9

Department of Chemical Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA.

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http://dx.doi.org/10.1021/bi101155rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964423PMC
November 2010

Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology.

PLoS Comput Biol 2010 Nov 11;6(11):e1000997. Epub 2010 Nov 11.

Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1000997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978700PMC
November 2010

Decreased secretion and unfolded protein response up-regulation are correlated with intracellular retention for single-chain antibody variants produced in yeast.

Biotechnol Bioeng 2009 Sep;104(1):20-9

Department of Chemical Engineering, University of Delaware, Newark, Delaware 19716, USA.

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http://dx.doi.org/10.1002/bit.22376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744959PMC
September 2009

Adalimumab safety in global clinical trials of patients with Crohn's disease.

Inflamm Bowel Dis 2009 Sep;15(9):1308-19

Hôpital Claude Huriez, Centre Hospitalier Universitaire de Lille, Lille, France.

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http://dx.doi.org/10.1002/ibd.20956DOI Listing
September 2009

A top-down approach to mechanistic biological modeling: application to the single-chain antibody folding pathway.

Biophys J 2008 Oct 18;95(8):3535-58. Epub 2008 Jul 18.

Department of Chemical Engineering, Department of Computer Science, University of California, Santa Barbara, California, USA.

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http://dx.doi.org/10.1529/biophysj.107.125039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553102PMC
October 2008

Nasal pathophysiology and its relationship to the female ovarian hormones.

J Otolaryngol Head Neck Surg 2008 Aug;37(4):540-6

Department of Otorhinolaryngology, Essex Rivers Healthcare NHS Trust, Colchester, United Kingdom.

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August 2008

Refolding of G protein alpha subunits from inclusion bodies expressed in Escherichia coli.

Protein Expr Purif 2008 Apr 8;58(2):342-55. Epub 2007 Dec 8.

Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.

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http://dx.doi.org/10.1016/j.pep.2007.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2282066PMC
April 2008

The effect of female hormone manipulation on nasal physiology.

Am J Rhinol 2007 Nov-Dec;21(6):675-9

Department of Otorhinolaryngology, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.

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March 2008

Heterologous GPCR expression: a bottleneck to obtaining crystal structures.

Biotechnol Prog 2007 May-Jun;23(3):540-7. Epub 2007 Mar 31.

Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19711, USA.

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http://dx.doi.org/10.1021/bp060349bDOI Listing
August 2007

High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor.

J Struct Biol 2007 Aug 16;159(2):166-78. Epub 2007 May 16.

Department of Chemical Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA.

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http://dx.doi.org/10.1016/j.jsb.2007.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994815PMC
August 2007

Paediatric periorbital cellulitis and its management.

Rhinology 2007 Mar;45(1):47-9

Otolaryngology Department, City Hospital, Dudley Road, Birmingham, United Kingdom.

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March 2007