Publications by authors named "Anne M Remes"

98Publications

The ethical implications of genetic testing in neurodegenerative diseases: A systematic review.

Scand J Caring Sci 2020 Nov 19. Epub 2020 Nov 19.

Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland.

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November 2020

C9orf72 Repeat Expansion Does Not Affect the Phenotype in Primary Progressive Aphasia.

J Alzheimers Dis 2020 ;78(3):919-925

Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland.

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January 2020

Corrigendum to "Risk factors for reactivation of clinical disease activity in multiple sclerosis after natalizumab cessation" [Multiple Sclerosis and Related Disorders 38 (2020) 101498].

Mult Scler Relat Disord 2020 Jun 18;41:102107. Epub 2020 Apr 18.

Tampere University Hospital, Department of Neurology, Teiskontie 35, 33520, Tampere, Finland; University of Eastern Finland, Department of Health and Social Management, Yliopistonranta 1, 70210, Kuopio, Finland.

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June 2020

Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium.

Neurodegener Dis Manag 2020 06 17;10(3):119-123. Epub 2020 Jun 17.

Molecular Neurodegeneration group, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.

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June 2020

Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease.

Dement Geriatr Cogn Disord 2020 2;49(1):98-106. Epub 2020 Jun 2.

Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland,

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June 2020

Risk factors for reactivation of clinical disease activity in multiple sclerosis after natalizumab cessation.

Mult Scler Relat Disord 2020 Feb 5;38:101498. Epub 2019 Nov 5.

Tampere University Hospital, Department of Neurology, Teiskontie 35, 33520 Tampere, Finland; University of Eastern Finland, Department of Health and Social Management, Yliopistonranta 1, 70210 Kuopio, Finland.

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February 2020

C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner.

Cells 2019 10 10;8(10). Epub 2019 Oct 10.

A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Neulaniementie 2, 70211 Kuopio, Finland.

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October 2019

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Authors:
Joshua C Bis Xueqiu Jian Brian W Kunkle Yuning Chen Kara L Hamilton-Nelson William S Bush William J Salerno Daniel Lancour Yiyi Ma Alan E Renton Edoardo Marcora John J Farrell Yi Zhao Liming Qu Shahzad Ahmad Najaf Amin Philippe Amouyel Gary W Beecham Jennifer E Below Dominique Campion Laura Cantwell Camille Charbonnier Jaeyoon Chung Paul K Crane Carlos Cruchaga L Adrienne Cupples Jean-François Dartigues Stéphanie Debette Jean-François Deleuze Lucinda Fulton Stacey B Gabriel Emmanuelle Genin Richard A Gibbs Alison Goate Benjamin Grenier-Boley Namrata Gupta Jonathan L Haines Aki S Havulinna Seppo Helisalmi Mikko Hiltunen Daniel P Howrigan M Arfan Ikram Jaakko Kaprio Jan Konrad Amanda Kuzma Eric S Lander Mark Lathrop Terho Lehtimäki Honghuang Lin Kari Mattila Richard Mayeux Donna M Muzny Waleed Nasser Benjamin Neale Kwangsik Nho Gaël Nicolas Devanshi Patel Margaret A Pericak-Vance Markus Perola Bruce M Psaty Olivier Quenez Farid Rajabli Richard Redon Christiane Reitz Anne M Remes Veikko Salomaa Chloe Sarnowski Helena Schmidt Michael Schmidt Reinhold Schmidt Hilkka Soininen Timothy A Thornton Giuseppe Tosto Christophe Tzourio Sven J van der Lee Cornelia M van Duijn Otto Valladares Badri Vardarajan Li-San Wang Weixin Wang Ellen Wijsman Richard K Wilson Daniela Witten Kim C Worley Xiaoling Zhang Celine Bellenguez Jean-Charles Lambert Mitja I Kurki Aarno Palotie Mark Daly Eric Boerwinkle Kathryn L Lunetta Anita L Destefano Josée Dupuis Eden R Martin Gerard D Schellenberg Sudha Seshadri Adam C Naj Myriam Fornage Lindsay A Farrer

Mol Psychiatry 2020 Aug;25(8):1901-1903

Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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August 2020

Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers.

Front Neurosci 2019 21;13:658. Epub 2019 Jun 21.

Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland.

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June 2019

CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics.

J Neurol Neurosurg Psychiatry 2019 10 5;90(10):1117-1123. Epub 2019 Jun 5.

Hydrocephalus Research Unit, Department of clinical neuroscience, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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October 2019

Copy number loss in is common among Finnish and Norwegian patients with iNPH.

Neurol Genet 2018 Dec 3;4(6):e291. Epub 2018 Dec 3.

Department of Neurosurgery (V.E.K., A. Jokinen, I.J., J.-M.L., A. Junkkari, J.E.J., V.L.), Kuopio University Hospital and University of Eastern Finland; Institute of Clinical Medicine-Neurology (S.H., M.H., H. Soininen, A.M.K.), University of Eastern Finland, Kuopio; Department of Neurosurgery (M.O., K.L.), University of Helsinki and Helsinki University Hospital; Clinical Neurosciences (C.A., A.K., J.F., J.R.), Department of Neurosurgery, University of Turku and Turku University Hospital; Department of Neurosurgery (A.R.), Tampere University Hospital; Unit of Clinical Neuroscience (M. Kauppinen, V.L.), Neurosurgery, University of Oulu and Medical Research Center, Oulu University Hospital; Institute of Biomedicine (M.H.), University of Eastern Finland, Kuopio; Analytical and Translational Genetics Unit (M. Kurki), Department of Medicine, Massachusetts General Hospital; Program in Medical and Population Genetics (M. Kurki), Broad Institute of MIT and Harvard; Stanley Center for Psychiatric Research (M. Kurki), Broad Institute for Harvard and MIT; Department of Neurology (H. Sato, T.K.), Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Japan; Medical Research Center (A.M.R.), Oulu University Hospital, Finland; Unit of Clinical Neuroscience (A.M.R.), Neurology, University of Oulu, Finland; Department of Neurosurgery (P.K.E.), Oslo University Hospital-Rikshospitalet; and Institute of Clinical Medicine (P.K.E.), Faculty of Medicine, University of Oslo, Norway.

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December 2018

BP180 Autoantibodies Target Different Epitopes in Multiple Sclerosis or Alzheimer's Disease than in Bullous Pemphigoid.

J Invest Dermatol 2019 02 10;139(2):293-299. Epub 2018 Oct 10.

Department of Dermatology, PEDEGO Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland. Electronic address:

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February 2019

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Authors:
Joshua C Bis Xueqiu Jian Brian W Kunkle Yuning Chen Kara L Hamilton-Nelson William S Bush William J Salerno Daniel Lancour Yiyi Ma Alan E Renton Edoardo Marcora John J Farrell Yi Zhao Liming Qu Shahzad Ahmad Najaf Amin Philippe Amouyel Gary W Beecham Jennifer E Below Dominique Campion Laura Cantwell Camille Charbonnier Jaeyoon Chung Paul K Crane Carlos Cruchaga L Adrienne Cupples Jean-François Dartigues Stéphanie Debette Jean-François Deleuze Lucinda Fulton Stacey B Gabriel Emmanuelle Genin Richard A Gibbs Alison Goate Benjamin Grenier-Boley Namrata Gupta Jonathan L Haines Aki S Havulinna Seppo Helisalmi Mikko Hiltunen Daniel P Howrigan M Arfan Ikram Jaakko Kaprio Jan Konrad Amanda Kuzma Eric S Lander Mark Lathrop Terho Lehtimäki Honghuang Lin Kari Mattila Richard Mayeux Donna M Muzny Waleed Nasser Benjamin Neale Kwangsik Nho Gaël Nicolas Devanshi Patel Margaret A Pericak-Vance Markus Perola Bruce M Psaty Olivier Quenez Farid Rajabli Richard Redon Christiane Reitz Anne M Remes Veikko Salomaa Chloe Sarnowski Helena Schmidt Michael Schmidt Reinhold Schmidt Hilkka Soininen Timothy A Thornton Giuseppe Tosto Christophe Tzourio Sven J van der Lee Cornelia M van Duijn Otto Valladares Badri Vardarajan Li-San Wang Weixin Wang Ellen Wijsman Richard K Wilson Daniela Witten Kim C Worley Xiaoling Zhang Celine Bellenguez Jean-Charles Lambert Mitja I Kurki Aarno Palotie Mark Daly Eric Boerwinkle Kathryn L Lunetta Anita L Destefano Josée Dupuis Eden R Martin Gerard D Schellenberg Sudha Seshadri Adam C Naj Myriam Fornage Lindsay A Farrer

Mol Psychiatry 2020 08 14;25(8):1859-1875. Epub 2018 Aug 14.

Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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August 2020

Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers.

J Neuroimmunol 2018 08 22;321:29-35. Epub 2018 May 22.

Institute of Clinical Medicine - Neurology, University of Eastern Finland, FI-70211 Kuopio, Finland; Neurocenter, Neurology, Kuopio University Hospital, FI-70029 Kuopio, Finland; Medical Research Center, Oulu University Hospital, FI-90014 Oulu, Finland; Unit of Clinical Neuroscience, Neurology, University of Oulu, FI-90014 Oulu, Finland. Electronic address:

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August 2018

Cardiac repolarization evolves differently during the course of benign and disabling multiple sclerosis.

Mult Scler Relat Disord 2018 Feb 1;20:205-209. Epub 2018 Feb 1.

Department of Neurology, Mikkeli Central Hospital, Mikkeli, Finland. Electronic address:

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February 2018

IgA antibodies to phosphocholine associate with long-term cardiovascular disease risk.

Atherosclerosis 2018 02 8;269:294-300. Epub 2017 Dec 8.

Medical Microbiology and Immunology, Research Unit of Biomedicine, University of Oulu, POB 5000, FI-90014, Finland; Medical Research Center and Nordlab Oulu, University Hospital, University of Oulu, POB 5000, Oulu FI-90014, Finland. Electronic address:

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February 2018

The impact of multiple sclerosis onset symptom on cardiac repolarization.

Brain Behav 2017 07 5;7(7):e00742. Epub 2017 Jun 5.

Department of Neurology Mikkeli Central Hospital Mikkeli Finland.

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July 2017

The Effect of Gray Matter ICA and Coefficient of Variation Mapping of BOLD Data on the Detection of Functional Connectivity Changes in Alzheimer's Disease and bvFTD.

Front Hum Neurosci 2016 9;10:680. Epub 2017 Jan 9.

Department of Diagnostic Radiology, Oulu University HospitalOulu, Finland; Oulu Functional NeuroImaging group, Research Unit of Medical Imaging, Physics and Technology, the Faculty of Medicine, University of OuluOulu, Finland; Medical Research Center Oulu, Oulu University HospitalOulu, Finland.

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January 2017

Lifetime antipsychotic medication and cognitive performance in schizophrenia at age 43 years in a general population birth cohort.

Psychiatry Res 2017 Jan 12;247:130-138. Epub 2016 Nov 12.

Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; Center for Life Course Health Research, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland; Oulu Occupational Health, Hallituskatu 36 B, 90100 Oulu, Finland. Electronic address:

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January 2017

Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer's Disease.

J Invest Dermatol 2017 01 17;137(1):71-76. Epub 2016 Sep 17.

Department of Dermatology, PEDEGO Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland. Electronic address:

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January 2017

Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease.

Dement Geriatr Cogn Dis Extra 2016 May-Aug;6(2):313-329. Epub 2016 Jul 22.

Neurology, Institute of Clinical Medicine, University of Eastern Finland, and Departments of, Tampere, Finland; Neurology, Kuopio University Hospital, Kuopio, Tampere, Finland.

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July 2016

Familial idiopathic normal pressure hydrocephalus.

J Neurol Sci 2016 Sep 25;368:11-8. Epub 2016 Jun 25.

Department of Neurosurgery, Kuopio University Hospital, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland. Electronic address:

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September 2016

Familial idiopathic normal pressure hydrocephalus.

J Neurol Sci 2016 Sep 25;368:11-8. Epub 2016 Jun 25.

Department of Neurosurgery, Kuopio University Hospital, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland. Electronic address:

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September 2016

The C9ORF72 expansion sizes in patients with psychosis: a population-based study on the Northern Finland Birth Cohort 1966.

Psychiatr Genet 2016 Apr;26(2):92-4

aInstitute of Clinical Medicine-Neurology bInstitute of Clinical Medicine-Psychiatry, Department of Medicine, University of Eastern Finland cDepartment of Psychiatry dDepartment of Neurology, Kuopio University Hospital, Kuopio eResearch Unit of Clinical Neuroscience, Department of Psychiatry fCenter for Life Course Health Research, University of Oulu gMedical Research Center Oulu, Oulu University Hospital, University of Oulu hDepartment of Psychiatry, Oulu University Hospital iDepartment of Psychiatry, South-Savonia Hospital District, Mikkeli jDepartment of Psychiatry, North Karelia Central Hospital, Joensuu kDepartment of Psychiatry, SOSTERI, Savonlinna lDepartment of Psychiatry, SOTE, Iisalmi mDepartment of Psychiatry, Lapland Hospital District, Rovaniemi, Finland.

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April 2016

Feasibility of radiological markers in idiopathic normal pressure hydrocephalus.

Acta Neurochir (Wien) 2015 Oct 21;157(10):1709-18; discussion 1719. Epub 2015 Jul 21.

Neurosurgery of NeuroCenter, Kuopio University Hospital and University of Eastern Finland, P.O. Box 100, FIN-70029, Kuopio, Finland.

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October 2015

A 13-year follow-up of Finnish patients with Salla disease.

J Neurodev Disord 2015 13;7(1):20. Epub 2015 Jul 13.

Department of Neurology, Oulu University Hospital, P.O. Box 20, 90029 Oulu, Finland ; Department of Clinical Medicine, Neurology, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland.

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July 2015

The Phenotype of the C9ORF72 Expansion Carriers According to Revised Criteria for bvFTD.

PLoS One 2015 6;10(7):e0131817. Epub 2015 Jul 6.

Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.

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April 2016

The CERAD Neuropsychological Battery in Patients with Frontotemporal Lobar Degeneration.

Dement Geriatr Cogn Dis Extra 2015 Jan-Apr;5(1):147-54. Epub 2015 Apr 14.

Institute of Clinical Medicine - Neurology, University of Eastern Finland, Finland ; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.

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May 2015

C9ORF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation.

Neurobiol Aging 2014 Jul 5;35(7):1780.e13-7. Epub 2014 Feb 5.

Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland. Electronic address:

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July 2014

Neurological comorbidity and survival in multiple sclerosis.

Mult Scler Relat Disord 2014 Jan 18;3(1):72-7. Epub 2013 Jul 18.

Institute of Clinical Medicine, Neurology, University of Eastern Finland, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland. Electronic address:

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January 2014

[Early diagnosis of Alzheimer's disease].

Duodecim 2013 ;129(19):2003-10

Itä-Suomen yliopiston lääketieteen laitos neurologian ja neurotieteen yksikkö, KYS:n neurokeskus.

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December 2013

Clinical Characteristics of C9ORF72-Linked Frontotemporal Lobar Degeneration.

Dement Geriatr Cogn Dis Extra 2013 20;3(1):251-62. Epub 2013 Aug 20.

Department of Neurology, Institute of Clinical Medicine, University of Oulu, Kuopio, Finland ; Clinical Research Center, Oulu University Hospital, Kuopio, Finland.

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September 2013

GroupICA dual regression analysis of resting state networks in a behavioral variant of frontotemporal dementia.

Front Hum Neurosci 2013 26;7:461. Epub 2013 Aug 26.

Department of Neurology, Institute of Clinical Medicine, University of Oulu Oulu, Finland ; Department of Neurology, Oulu University Hospital Oulu, Finland.

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August 2013

Diagnosis of dementia as a turning point among Finnish families: a qualitative study.

Nurs Health Sci 2013 Dec 3;15(4):489-96. Epub 2013 Jun 3.

Institute of Health Sciences, Nursing Science, University of Oulu, Oulu, Finland; Oulu University Hospital, Oulu, Finland.

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December 2013

Diagnosis of dementia as a turning point among Finnish families: a qualitative study.

Nurs Health Sci 2013 Dec 3;15(4):489-96. Epub 2013 Jun 3.

Institute of Health Sciences, Nursing Science, University of Oulu, Oulu, Finland; Oulu University Hospital, Oulu, Finland.

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December 2013

[Posterior variant of Alzheimer's disease and other atypical symptom pictures].

Duodecim 2013 ;129(3):244-50

KYS, neurokeskus, neurologia Itä-Suomen yliopisto, kliinisen lääketieteen yksikkö, neurologia.

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April 2013

An Unusual Developmental Profile of Salla Disease in a Patient with the SallaFIN Mutation.

Case Rep Neurol Med 2012 22;2012:615721. Epub 2012 Nov 22.

Department of Neurology, Oulu University Hospital, P.O. Box 20, 90029 Oulu, Finland ; Department of Clinical Medicine, Neurology, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland.

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December 2012

Prevalence of the primary LHON mutations in Northern Finland associated with bilateral optic atrophy and tobacco-alcohol amblyopia.

Acta Ophthalmol 2013 Nov 12;91(7):630-4. Epub 2012 Sep 12.

Department of Ophthalmology, Institute of Clinical Medicine, University of Oulu and Clinical Research Center, Oulu University Hospital, Oulu, FinlandDepartment of Neurology, Institute of Clinical Medicine, University of Oulu and Clinical Research Center, Oulu University Hospital, Oulu, FinlandDepartment of Pediatrics, Institute of Clinical Medicine, University of Oulu and Clinical Research Center, Oulu University Hospital, Oulu, FinlandDepartment of Neurology, Institute of Clinical Medicine, University of Eastern, FinlandDepartment of Neurology, Kuopio University Hospital, Finland.

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November 2013

Novel TARDBP sequence variant and C9ORF72 repeat expansion in a family with frontotemporal dementia.

Alzheimer Dis Assoc Disord 2014 Apr-Jun;28(2):190-3

Departments of *Neurology ‡Ophthalmology, Institute of Clinical Medicine, University of Oulu †Clinical Research Center, Oulu University Hospital, Oulu, Finland §Neuromuscular Diseases Research Unit, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD ∥Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland ¶Department of Neurology, Kuopio University Hospital, Kuopio, Finland.

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January 2015

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.

Neuron 2011 Oct 21;72(2):257-68. Epub 2011 Sep 21.

Neuromuscular Diseases Research Unit, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.

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October 2011

[Frontotemporal lobar degeneration: a diagnostic challenge].

Authors:
Anne M Remes

Duodecim 2010 ;126(18):2189-95

kliinisen lääketieteen laitos, neurologian klinikka ja OYS, klinisen tutkimuksen keskus, PL 5000, 90014 Oulun yliopisto.

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December 2010

Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration.

Mol Neurodegener 2010 Feb 2;5. Epub 2010 Feb 2.

Institute of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland.

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February 2010

Cerebrospinal fluid antibodies to oxidized LDL are increased in Alzheimer's disease.

Neurobiol Dis 2009 Mar 16;33(3):467-72. Epub 2008 Dec 16.

Department of Neurology, University of Oulu, Oulu, Finland.

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March 2009

Amyloid myopathy: a diagnostic challenge.

Neurol Int 2009 Nov 16;1(1):e7. Epub 2009 Nov 16.

Department of Neurology, University of Oulu.

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November 2009

Differential metabolic consequences of fumarate hydratase and respiratory chain defects.

Biochim Biophys Acta 2008 May 14;1782(5):287-94. Epub 2008 Feb 14.

Program of Molecular Neurology Biomedicum-Helsinki, Finland.

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May 2008