Anne M Griffiths

Anne M Griffiths

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Anne M Griffiths

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Intensified Infliximab Induction is Associated with Improved Response and Decreased Colectomy in Steroid-Refractory Paediatric Ulcerative Colitis.

J Crohns Colitis 2019 Aug;13(8):982-989

Division of Gastroenterology, Hepatology & Nutrition, Department of Paediatrics, University of Toronto, Toronto, ON, Canada.

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https://academic.oup.com/ecco-jcc/advance-article/doi/10.109
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http://dx.doi.org/10.1093/ecco-jcc/jjz019DOI Listing
August 2019

Clinical value of fecal calprotectin.

Crit Rev Clin Lab Sci 2019 Aug 6;56(5):307-320. Epub 2019 Jun 6.

a Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children , University of Toronto , Toronto , Canada.

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http://dx.doi.org/10.1080/10408363.2019.1619159DOI Listing
August 2019

The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World.

Can J Gastroenterol Hepatol 2018 12;2018:3190548. Epub 2018 Jun 12.

Division of Gastroenterology, Hepatology & Nutrition, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1155/2018/3190548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020509PMC
February 2019

Clinical Outcomes With Therapeutic Drug Monitoring in Inflammatory Bowel Disease: A Systematic Review With Meta-Analysis.

J Crohns Colitis 2018 Nov;12(11):1302-1315

Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1093/ecco-jcc/jjy109DOI Listing
November 2018

Biologics Delay Progression of Crohn's Disease, but Not Early Surgery, in Children.

Clin Gastroenterol Hepatol 2018 09 2;16(9):1467-1473. Epub 2018 Mar 2.

Pediatric Gastroenterology and Nutrition, Hasbro Children Hospital, Providence, Rhode Island; The Warren Alpert Medical School, Brown University, Providence, Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.02.027DOI Listing
September 2018

Symptoms Do Not Correlate With Findings From Colonoscopy in Children With Inflammatory Bowel Disease and Primary Sclerosing Cholangitis.

Clin Gastroenterol Hepatol 2018 07 24;16(7):1098-1105.e1. Epub 2018 Mar 24.

Division of Gastroenterology, Hepatology and Nutrition, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.01.020DOI Listing
July 2018

Associations Among Mucosal and Transmural Healing and Fecal Level of Calprotectin in Children With Crohn's Disease.

Clin Gastroenterol Hepatol 2018 07 2;16(7):1089-1097.e4. Epub 2018 Mar 2.

The Juliet Keidan Institute of Pediatric Gastroenterology, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.01.024DOI Listing
July 2018

Can MR enterography screen for perianal disease in pediatric inflammatory bowel disease?

J Magn Reson Imaging 2018 06 14;47(6):1638-1645. Epub 2017 Nov 14.

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.25888DOI Listing
June 2018

Diagnostic delay in Canadian children with inflammatory bowel disease is more common in Crohn's disease and associated with decreased height.

Arch Dis Child 2018 04 9;103(4):319-326. Epub 2017 Aug 9.

Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/archdischild-2017-313060DOI Listing
April 2018

New Onset Autoimmune Hepatitis during Anti-Tumor Necrosis Factor-Alpha Treatment in Children.

J Pediatr 2018 03 21;194:128-135.e1. Epub 2017 Dec 21.

Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2017.10.071DOI Listing
March 2018

The IBD and PSC Phenotypes of PSC-IBD.

Curr Gastroenterol Rep 2018 Mar 28;20(4):16. Epub 2018 Mar 28.

Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, M5G1X8, Canada.

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http://dx.doi.org/10.1007/s11894-018-0620-2DOI Listing
March 2018

Fecal Microbial Transplantation for Pediatric Ulcerative Colitis: Are We There Yet?

J Pediatr Gastroenterol Nutr 2017 Oct 27. Epub 2017 Oct 27.

*Edmonton Pediatric IBD Clinic (EPIC), Department of Pediatrics, University of Alberta, Edmonton, AB, Canada†Inflammatory Bowel Disease Centre, Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MPG.0000000000001811DOI Listing
October 2017

Characterizing the Posttransfer Period Among Patients with Pediatric Onset IBD: The Impact of Academic Versus Community Adult Care on Emergent Health Resource Utilization.

Inflamm Bowel Dis 2017 09;23(9):1483-1491

*Division of Gastroenterology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada; †Department of Pediatrics, Children's Hospital of Eastern Ontario, School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada; ‡Sick Kids, Division of Gastroenterology Hepatology and Nutrition, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada; §Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon; ‖Mount Sinai Hospital Centre for Inflammatory Bowel Disease, University of Toronto, Toronto, Ontario, Canada; and ¶Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000001200DOI Listing
September 2017

Growth Improvement with Adalimumab Treatment in Children with Moderately to Severely Active Crohn's Disease.

Inflamm Bowel Dis 2017 06;23(6):967-975

*Department of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada; †Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN; ‡Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA; §Department of Pediatric Gastroenterology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands; ‖Department of Pediatrics, Pediatric Gastroenterology, Universite Sorbonne Paris-Cite, Hospital Necker-Enfants Malades, Paris, France; ¶Division of Digestive Diseases, Hepatology and Nutrition, Connecticut Children's Medical Center, Hartford, CT; **AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany; and ††AbbVie Inc., North Chicago, IL.

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http://dx.doi.org/10.1097/MIB.0000000000001075DOI Listing
June 2017

Magnetic resonance enterography has good inter-rater agreement and diagnostic accuracy for detecting inflammation in pediatric Crohn disease.

Pediatr Radiol 2017 May 10;47(5):565-575. Epub 2017 Mar 10.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00247-017-3790-4DOI Listing
May 2017

Item Generation and Reduction Toward Developing a Patient-reported Outcome for Pediatric Ulcerative Colitis (TUMMY-UC).

J Pediatr Gastroenterol Nutr 2017 03;64(3):373-377

*Shaare Zedek Medical Center †Hebrew University of Jerusalem, Jerusalem, Israel ‡Children's Hospital of Eastern Ontario and Research Institute, Ottawa, Canada §IWK Health Centre, Halifax, Canada ||National Children's Research Centre and University College Dublin, Dublin, Ireland ¶University of North Carolina Health Care, Chapel Hill, NC #Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK **The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1097/MPG.0000000000001259DOI Listing
March 2017

Which PCDAI Version Best Reflects Intestinal Inflammation in Pediatric Crohn Disease?

J Pediatr Gastroenterol Nutr 2017 02;64(2):254-260

*Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem †Pediatric Gastroenterology Unit, Wolfson Medical Center, Tel Aviv University, Holon, Israel ‡Hospital for Sick Children, Toronto, Ontario §IWK Health Centre, Halifax, Nova Scotia, Canada ||Children's Hospital, Málaga, Spain ¶Hauner Children's Hospital, Munich, Germany #Children's Hospital of Philadelphia, Philadelphia, PA **Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada ††Connecticut Children's Medical Center, Hartford.

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http://dx.doi.org/10.1097/MPG.0000000000001227DOI Listing
February 2017

Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease.

Gastroenterology 2016 05 4;150(5):1196-1207. Epub 2016 Feb 4.

SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085160012
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http://dx.doi.org/10.1053/j.gastro.2016.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842103PMC
May 2016

Time for Personalized Biologic Therapy: One Size Does Not Fit All.

Authors:
Anne M Griffiths

J Pediatr Gastroenterol Nutr 2016 05;62(5):666-7

Inflammatory Bowel Disease Centre, Hospital for Sick Children, Professor of Paediatrics, University of Toronto, Canada.

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http://dx.doi.org/10.1097/MPG.0000000000001149DOI Listing
May 2016

Abdominal X-ray in Pediatric Acute Severe Colitis and Radiographic Predictors of Response to Intravenous Steroids.

J Pediatr Gastroenterol Nutr 2016 Feb;62(2):259-63

*Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition, Shaare Zedek Medical Center †Hebrew University of Jerusalem, Jerusalem, Israel ‡Alder Hey Children's NHS Foundation Trust, Liverpool, UK §Children's Hospital of Eastern Ontario IBD Centre ||Department of Pediatrics, University of Ottawa, Ottawa, Canada ¶Connecticut Children's Medical Center, Hartford, CT #Nationwide Children's Hospital, Ohio State University, Columbus **SickKids Hospital, University of Toronto, Toronto, Canada.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPG.0000000000000910DOI Listing
February 2016

Use of Placebo in Pediatric Inflammatory Bowel Diseases: A Position Paper From ESPGHAN, ECCO, PIBDnet, and the Canadian Children IBD Network.

J Pediatr Gastroenterol Nutr 2016 Jan;62(1):183-7

*European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), Warsaw, Poland †European Crohn's and Colitis Organization (ECCO), Vienna, Austria ‡Global Pediatric IBD Network (PIBDnet) §Canadian Children IBD Network (a joint partnership of the Canadian Institutes of Health Research and the CH.I.L.D. Foundation), Toronto, ON, Canada ||Institute of Pediatric Gastroenterology, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel ¶Ludwig-Maximilians-University of Munich, Dr von Hauner Children's Hospital, University of Munich Medical Center-Klinikum der Universität München, München, Germany #The Hospital for Sick Children, University of Toronto, ON, Canada **Connecticut Children's Medical Center, Hartford ††Department of Pediatrics, Feinstein IBD Center, Icahn School of Medicine, Mount Sinai, New York, NY ‡‡Department of Pediatric Gastroenterology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands §§Department Neurofarba, University of Florence-Meyer Hospital, Florence |||| "La Sapienza" University of Rome, Rome, Italy ¶¶Department of Pediatrics, Children's Hospital Medical Center, University Hospitals, Bonn, Germany ##University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands ***Royal Hospital for Children, Glasgow, UK †††Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada ‡‡‡Children's University Hospital, Brussels §§§University Hospitals Gasthuisberg, Leuven, Belgium ||||||Hôpital Necker-Enfants Malades, Paris, France.

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http://dx.doi.org/10.1097/MPG.0000000000001024DOI Listing
January 2016

Efficacy of oral methotrexate in paediatric Crohn's disease: a multicentre propensity score study.

Gut 2015 Dec 21;64(12):1898-904. Epub 2014 Nov 21.

Division of GI/Hepatology/Nutrition, SickKids Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/gutjnl-2014-307964DOI Listing
December 2015

Abnormal Liver Biochemistry Is Common in Pediatric Inflammatory Bowel Disease: Prevalence and Associations.

Inflamm Bowel Dis 2015 Dec;21(12):2848-56

*Division of Gastroenterology, Hepatology, and Nutrition, The University of Toronto, ON, Canada; †Department of Pediatrics, The University of Toronto, Toronto, ON, Canada; ‡Institute of Health Policy, Management and Evaluation, The University of Toronto, Toronto, ON, Canada; §Child Health Evaluative Sciences, Hospital for Sick Children and The University of Toronto, Toronto, ON, Canada; and ‖Division of Rheumatology, The University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000558DOI Listing
December 2015

Comparative Effectiveness of Nutritional and Biological Therapy in North American Children with Active Crohn's Disease.

Inflamm Bowel Dis 2015 Aug;21(8):1786-93

*Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; †Department of Pediatric, Division of Gastroenterology and Nutrition Seattle Children's Hospital, Seattle, Washington; and University of Washington; ‡Department of Pediatrics, IWK Health Centre, Halifax, NS, Canada; §Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; ||School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania; ¶Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; **Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and ††Department of Medicine, Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://pdfs.journals.lww.com/ibdjournal/2015/08000/Comparati
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http://dx.doi.org/10.1097/MIB.0000000000000426DOI Listing
August 2015

Paneth cell marker CD24 in NOD2 knockout organoids and in inflammatory bowel disease (IBD).

Gut 2015 Feb 23;64(2):353-4. Epub 2013 May 23.

Department of Child Life and Health, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1136/gutjnl-2013-305077DOI Listing
February 2015

Liver enzyme elevations within 3 months of diagnosis of inflammatory bowel disease and likelihood of liver disease.

J Pediatr Gastroenterol Nutr 2014 Sep;59(3):321-3

*Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA †Connecticut Children's Medical Center, Hartford ‡Hasbro Children's Hospital, Providence, RI §I.W.K. Health Center, Halifax, Nova Scotia, Canada ||Hospital for Sick Children, Toronto, Ontario, Canada ¶Goryeb Children's Hospital, Morristown, NJ #Children's Hospital of Wisconsin, Milwaukee **Johns Hopkins Hospital, Baltimore, MD ††Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada ‡‡Children's Medical Center, Dayton, OH §§Riley Hospital for Children, Indianapolis, IN ||||Nationwide Children's Hospital, Columbus, OH ¶¶Children's Hospital of Philadelphia, Philadelphia, PA ##Russell Children's Hospital, Birmingham, AB ***University of Minnesota, Minneapolis †††University of North Carolina, Chapel Hill ‡‡‡Cincinnati Children's Medical Center, Cincinnati, OH §§§Mayo Clinic, Rochester, MN ||||||Penn State Hershey Children's Hospital, Hershey, PA ¶¶¶Cohen Children's Medical Center, New Hyde Park, NY.

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http://dx.doi.org/10.1097/MPG.0000000000000409DOI Listing
September 2014

Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease.

Gastroenterology 2014 Sep 12;147(3):680-689.e2. Epub 2014 Jun 12.

SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.06.005DOI Listing
September 2014

Retrospective cohort study of methotrexate use in the treatment of pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Aug;20(8):1341-5

1Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; 2Department of Pediatrics, Connecticut Children's Medical Center, Hartford, Connecticut; 3Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; 4Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canada; 5Department of Pediatrics, I.W.K. Health Center, Halifax, NS, Canada; 6Pediatric Gastroenterology, Goryeb Children's Hospital, Morristown, New Jersey; 7Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio; 8Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; 9Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; 10Section of Gastroenterology/Hepatology/Nutrition, Riley Hospital for Children, Indianapolis, Indiana; 11Department of Gastroenterology, Dayton Children's, Dayton, Ohio; 12Division of Pediatric Gastroenterology, Nutrition and Liver Diseases, Hasbro Children's Hospital, Providence, Rhode Island; 13Department of Pediatrics, Russell Children's Hospital, Birmingham, Alabama; 14Division of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland; 15Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Medical Center, Cincinnati, Ohio; 16Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina; and 17Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New York.

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http://dx.doi.org/10.1097/MIB.0000000000000102DOI Listing
August 2014

Infliximab maintains durable response and facilitates catch-up growth in luminal pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Jul;20(7):1177-86

*Division of Gastroenterology, Hepatology and Nutrition, Department of Paediatrics, University of Toronto, Toronto, ON, Canada; †SickKids Inflammatory Bowel Disease Center, The Hospital for Sick Children, Toronto, ON, Canada; and ‡Cell Biology Program, Research Institute and the Institute of Medical Science, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000083DOI Listing
July 2014

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Jun;20(6):1037-48

1Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Divisions of 2Allergy and Immunology and 3Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; 4Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; 5Division of Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; 6Division of Pediatric Gastroenterology and Nutrition, Cohen Children's Medical Center of New York, New Hyde Park, New York; 7Department of Pediatric Gastroenterology and Nutrition, Goryeb Children's Hospital/Atlantic Health System, Morristown, New Jersey; 8Division of Pediatric Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, Columbus, Ohio; 9Department of Pediatrics, University of California, San Francisco, San Francisco, California; 10Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; 11Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; 12Digestive Diseases and Nutrition Center, Department of Pediatrics, University at Buffalo, Buffalo, New York; 13Division of Digestive Diseases and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut; and 14Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1097/MIB.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151275PMC
June 2014

Challenging question: can we diagnose Crohn's disease without histology?

Authors:
Anne M Griffiths

Dig Dis 2013 6;31(2):202-6. Epub 2013 Sep 6.

Division of Gastroenterology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Ont., Canada.

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http://dx.doi.org/10.1159/000353368DOI Listing
May 2014

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

Gastroenterology 2014 Apr 11;146(4):1028-39. Epub 2014 Jan 11.

SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002656PMC
April 2014

Hepatotoxicity caused by methotrexate therapy in children with inflammatory bowel disease: a systematic review and meta-analysis.

Inflamm Bowel Dis 2014 Jan;20(1):47-59

1Division of Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; 2Neonatal Intensive Care Unit, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada; 3Department of Clinical Epidemiology and Biostatistics, McMaster University, Toronto, ON, Canada; and 4Division of Rheumatology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/01.MIB.0000436953.88522.3eDOI Listing
January 2014

Interleukin-6 is associated with steroid resistance and reflects disease activity in severe pediatric ulcerative colitis.

J Crohns Colitis 2013 Dec 20;7(11):916-22. Epub 2013 Jan 20.

Department of Pediatrics, University of Alberta, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.crohns.2012.12.012DOI Listing
December 2013

Endoscopic and clinical variables that predict sustained remission in children with ulcerative colitis treated with infliximab.

Clin Gastroenterol Hepatol 2013 Nov 11;11(11):1460-5. Epub 2013 May 11.

Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2013.04.049DOI Listing
November 2013

More on lymphoproliferative disorders associated with crohn disease treatments.

Authors:
Anne M Griffiths

J Pediatr Gastroenterol Nutr 2013 Aug;57(2):131-2

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http://dx.doi.org/10.1097/MPG.0b013e31829ae499DOI Listing
August 2013

Serum antibodies associated with complex inflammatory bowel disease.

Inflamm Bowel Dis 2013 Jun;19(7):1499-505

The Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MIB.0b013e318281f2a1DOI Listing
June 2013

Alterations in the gut microbiome of children with severe ulcerative colitis.

Inflamm Bowel Dis 2012 Oct 14;18(10):1799-808. Epub 2011 Dec 14.

Department of Pediatric Gastroenterology and Nutrition, University of Southern California, Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1002/ibd.22860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319508PMC
October 2012

Medical therapy for pediatric inflammatory bowel disease.

Curr Gastroenterol Rep 2012 Apr;14(2):166-73

Division of Gastroenterology, McMaster Children's Hospital, Hamilton, Canada.

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http://dx.doi.org/10.1007/s11894-012-0249-5DOI Listing
April 2012

Treatment of hospitalized adult patients with severe ulcerative colitis: Toronto consensus statements.

Am J Gastroenterol 2012 Feb 22;107(2):179-94; author reply 195. Epub 2011 Nov 22.

McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1038/ajg.2011.386DOI Listing
February 2012

Mathematical weighting of the pediatric Crohn's disease activity index (PCDAI) and comparison with its other short versions.

Inflamm Bowel Dis 2012 Jan 23;18(1):55-62. Epub 2011 Feb 23.

Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Israel.

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http://dx.doi.org/10.1002/ibd.21649DOI Listing
January 2012

Genetic profiling in inflammatory bowel disease: from association to bedside.

Gastroenterology 2011 Nov 19;141(5):1566-71.e1. Epub 2011 Sep 19.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2011.09.018DOI Listing
November 2011

Changes to surgical and hospitalization rates of pediatric inflammatory bowel disease in Ontario, Canada (1994-2007).

Inflamm Bowel Dis 2011 Oct 22;17(10):2153-61. Epub 2010 Dec 22.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ibd.21591DOI Listing
October 2011

C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) or both? A systematic evaluation in pediatric ulcerative colitis.

J Crohns Colitis 2011 Oct 2;5(5):423-9. Epub 2011 Jun 2.

Pediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.crohns.2011.05.003DOI Listing
October 2011

Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.

Inflamm Bowel Dis 2011 Sep 10;17(9):1936-42. Epub 2010 Dec 10.

Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/ibd.21579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164287PMC
September 2011

Development and use of reporting guidelines for assessing the quality of validation studies of health administrative data.

J Clin Epidemiol 2011 Aug 30;64(8):821-9. Epub 2010 Dec 30.

The Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jclinepi.2010.10.006DOI Listing
August 2011

Use of C-reactive protein in children with newly diagnosed inflammatory bowel disease.

J Pediatr 2011 Aug 8;159(2):340-2. Epub 2011 Jun 8.

Department of Pediatrics, University of Ottawa and Children's Hospital of Eastern Ontario Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jpeds.2011.04.028DOI Listing
August 2011

Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis.

Inflamm Bowel Dis 2011 Aug 3;17(8):1726-30. Epub 2010 Dec 3.

Division of Digestive Diseases, Hepatology and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut, USA.

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http://dx.doi.org/10.1002/ibd.21561DOI Listing
August 2011

Replication of genetic variation in the MYO9B gene in Crohn's disease.

Hum Immunol 2011 Jul 12;72(7):592-7. Epub 2011 Apr 12.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1016/j.humimm.2011.03.025DOI Listing
July 2011

Outcomes of pediatric inflammatory bowel disease: socioeconomic status disparity in a universal-access healthcare system.

J Pediatr 2011 Jun 12;158(6):960-967.e1-4. Epub 2011 Jan 12.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S002234761001010
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http://dx.doi.org/10.1016/j.jpeds.2010.11.039DOI Listing
June 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Acute severe ulcerative colitis in children: a systematic review.

Inflamm Bowel Dis 2011 Jan;17(1):440-9

Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.

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https://academic.oup.com/ibdjournal/article/17/1/440-449/463
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http://dx.doi.org/10.1002/ibd.21383DOI Listing
January 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010