Publications by authors named "Anne Langsted"

46Publications

AHRR hypomethylation as an epigenetic marker of smoking history predicts risk of myocardial infarction in former smokers.

Atherosclerosis 2020 Nov 7;312:8-15. Epub 2020 Sep 7.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.08.034DOI Listing
November 2020

Reply to: "Methodological issues regarding: "A third of nonfasting plasma cholesterol is in remnant lipoproteins: Lipoprotein subclass profiling in 9293 individuals".

Atherosclerosis 2020 06 9;302:57-58. Epub 2020 Apr 9.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.03.027DOI Listing
June 2020

Lipoprotein(a): is it more, less or equal to LDL as a causal factor for cardiovascular disease and mortality?

Curr Opin Lipidol 2020 06;31(3):125-131

Department of Clinical Biochemistry.

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http://dx.doi.org/10.1097/MOL.0000000000000681DOI Listing
June 2020

Triglycerides and remnant cholesterol associated with risk of aortic valve stenosis: Mendelian randomization in the Copenhagen General Population Study.

Eur Heart J 2020 Jun;41(24):2288-2299

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Borgmester Ib Juuls Vej 73, Elevator 7, DK-2730 Herlev, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehaa172DOI Listing
June 2020

Obesity as a Causal Risk Factor for Aortic Valve Stenosis.

J Am Coll Cardiol 2020 01;75(2):163-176

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.10.050DOI Listing
January 2020

Low High-Density Lipoprotein Cholesterol to Monitor Long-Term Average Increased Triglycerides.

J Clin Endocrinol Metab 2020 Apr;105(4)

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1210/clinem/dgz265DOI Listing
April 2020

Lipoprotein(a)-Lowering by 50 mg/dL (105 nmol/L) May Be Needed to Reduce Cardiovascular Disease 20% in Secondary Prevention: A Population-Based Study.

Arterioscler Thromb Vasc Biol 2020 01 3;40(1):255-266. Epub 2019 Oct 3.

From the Department of Clinical Biochemistry (C.M.M., P.R.K., A.L., A.V., B.G.N.), Copenhagen University Hospital, Denmark.

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http://dx.doi.org/10.1161/ATVBAHA.119.312951DOI Listing
January 2020

Response to 'Lipoprotein(a): it is not the cholesterol content: it is the apolipoprotein(a)!'

Eur Heart J 2019 11;40(43):3577

Department of Clinical Chemistry, Herlev University Hospital, Herlev Ringvej 75, Herlev, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehz607DOI Listing
November 2019

Lipoprotein(a) Should Be Measured in All Individuals Suspected of Having Familial Hypercholesterolemia.

Clin Chem 2019 10 6;65(10):1190-1192. Epub 2019 Aug 6.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark;

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http://dx.doi.org/10.1373/clinchem.2019.308650DOI Listing
October 2019

Elevated Lipoprotein(a) and Risk of Ischemic Stroke.

J Am Coll Cardiol 2019 07;74(1):54-66

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.03.524DOI Listing
July 2019

Reply to: "Seasonal variations of lipid profiles in a French cohort".

Atherosclerosis 2019 07 24;286:184-186. Epub 2019 May 24.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.05.015DOI Listing
July 2019

Antisense Oligonucleotides Targeting Lipoprotein(a).

Curr Atheroscler Rep 2019 05 20;21(8):30. Epub 2019 May 20.

Department of Clinical Biochemistry, Herlev Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, DK-2730, Herlev, Denmark.

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http://dx.doi.org/10.1007/s11883-019-0792-8DOI Listing
May 2019

A third of nonfasting plasma cholesterol is in remnant lipoproteins: Lipoprotein subclass profiling in 9293 individuals.

Atherosclerosis 2019 07 9;286:97-104. Epub 2019 May 9.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.05.011DOI Listing
July 2019

The Christmas holidays are immediately followed by a period of hypercholesterolemia.

Atherosclerosis 2019 02 19;281:121-127. Epub 2018 Dec 19.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.12.011DOI Listing
February 2019

High lipoprotein(a) and high risk of mortality.

Eur Heart J 2019 09;40(33):2760-2770

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, DK Herlev, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehy902DOI Listing
September 2019

Smoking is Associated with Increased Risk of Major Bleeding: A Prospective Cohort Study.

Thromb Haemost 2019 Jan 31;119(1):39-47. Epub 2018 Dec 31.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1055/s-0038-1675798DOI Listing
January 2019

Nonfasting versus fasting lipid profile for cardiovascular risk prediction.

Pathology 2019 Feb 3;51(2):131-141. Epub 2018 Dec 3.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.pathol.2018.09.062DOI Listing
February 2019

Advances in lipid-lowering therapy through gene-silencing technologies.

Nat Rev Cardiol 2018 05 8;15(5):261-272. Epub 2018 Feb 8.

Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsveg 3B, 2200 Copenhagen, Denmark.

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http://www.nature.com/doifinder/10.1038/nrcardio.2018.3
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http://dx.doi.org/10.1038/nrcardio.2018.3DOI Listing
May 2018

Exome-wide association study of plasma lipids in >300,000 individuals.

Authors:
Dajiang J Liu Gina M Peloso Haojie Yu Adam S Butterworth Xiao Wang Anubha Mahajan Danish Saleheen Connor Emdin Dewan Alam Alexessander Couto Alves Philippe Amouyel Emanuele Di Angelantonio Dominique Arveiler Themistocles L Assimes Paul L Auer Usman Baber Christie M Ballantyne Lia E Bang Marianne Benn Joshua C Bis Michael Boehnke Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Ivan Brandslund Morris Brown Fabio Busonero Mark J Caulfield John C Chambers Daniel I Chasman Y Eugene Chen Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu John M Connell Francesco Cucca L Adrienne Cupples Scott M Damrauer Gail Davies Ian J Deary George Dedoussis Joshua C Denny Anna Dominiczak Marie-Pierre Dubé Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Aliki-Eleni Farmaki Mary F Feitosa Marco Ferrario Jean Ferrieres Ian Ford Myriam Fornage Paul W Franks Timothy M Frayling Ruth Frikke-Schmidt Lars G Fritsche Philippe Frossard Valentin Fuster Santhi K Ganesh Wei Gao Melissa E Garcia Christian Gieger Franco Giulianini Mark O Goodarzi Harald Grallert Niels Grarup Leif Groop Megan L Grove Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Joel N Hirschhorn Oddgeir L Holmen Jennifer Huffman Yong Huo Kristian Hveem Sehrish Jabeen Anne U Jackson Johanna Jakobsdottir Marjo-Riitta Jarvelin Gorm B Jensen Marit E Jørgensen J Wouter Jukema Johanne M Justesen Pia R Kamstrup Stavroula Kanoni Fredrik Karpe Frank Kee Amit V Khera Derek Klarin Heikki A Koistinen Jaspal S Kooner Charles Kooperberg Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo Lakka Claudia Langenberg Anne Langsted Lenore J Launer Torsten Lauritzen David C M Liewald Li An Lin Allan Linneberg Ruth J F Loos Yingchang Lu Xiangfeng Lu Reedik Mägi Anders Malarstig Ani Manichaikul Alisa K Manning Pekka Mäntyselkä Eirini Marouli Nicholas G D Masca Andrea Maschio James B Meigs Olle Melander Andres Metspalu Andrew P Morris Alanna C Morrison Antonella Mulas Martina Müller-Nurasyid Patricia B Munroe Matt J Neville Jonas B Nielsen Sune F Nielsen Børge G Nordestgaard Jose M Ordovas Roxana Mehran Christoper J O'Donnell Marju Orho-Melander Cliona M Molony Pieter Muntendam Sandosh Padmanabhan Colin N A Palmer Dorota Pasko Aniruddh P Patel Oluf Pedersen Markus Perola Annette Peters Charlotta Pisinger Giorgio Pistis Ozren Polasek Neil Poulter Bruce M Psaty Daniel J Rader Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Stephen S Rich Paul M Ridker John D Rioux Neil R Robertson Dan M Roden Jerome I Rotter Igor Rudan Veikko Salomaa Nilesh J Samani Serena Sanna Naveed Sattar Ellen M Schmidt Robert A Scott Peter Sever Raquel S Sevilla Christian M Shaffer Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert V Smith Blair H Smith Sangeetha Somayajula Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kathleen E Stirrups Nathan Stitziel Konstantin Strauch Heather M Stringham Praveen Surendran Hayato Tada Alan R Tall Hua Tang Jean-Claude Tardif Kent D Taylor Stella Trompet Philip S Tsao Jaakko Tuomilehto Anne Tybjaerg-Hansen Natalie R van Zuydam Anette Varbo Tibor V Varga Jarmo Virtamo Melanie Waldenberger Nan Wang Nick J Wareham Helen R Warren Peter E Weeke Joshua Weinstock Jennifer Wessel James G Wilson Peter W F Wilson Ming Xu Hanieh Yaghootkar Robin Young Eleftheria Zeggini He Zhang Neil S Zheng Weihua Zhang Yan Zhang Wei Zhou Yanhua Zhou Magdalena Zoledziewska Joanna M M Howson John Danesh Mark I McCarthy Chad A Cowan Goncalo Abecasis Panos Deloukas Kiran Musunuru Cristen J Willer Sekar Kathiresan

Nat Genet 2017 Dec 30;49(12):1758-1766. Epub 2017 Oct 30.

Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709146PMC
December 2017

High Lipoprotein(a) and Low Risk of Major Bleeding in Brain and Airways in the General Population: a Mendelian Randomization Study.

Clin Chem 2017 Nov 6;63(11):1714-1723. Epub 2017 Sep 6.

Department of Clinical Biochemistry and

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http://dx.doi.org/10.1373/clinchem.2017.276931DOI Listing
November 2017

Reply to: "Appropriate use of cholesterol-lowering therapy".

Atherosclerosis 2017 07 10;262:200-201. Epub 2017 Mar 10.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.03.017DOI Listing
July 2017

Hypertriglyceridemia and Pancreatitis-New Evidence That Less Is More-Reply.

JAMA Intern Med 2017 05;177(5):745-746

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark2Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1001/jamainternmed.2017.0616DOI Listing
May 2017

Remnant Cholesterol Elicits Arterial Wall Inflammation and a Multilevel Cellular Immune Response in Humans.

Arterioscler Thromb Vasc Biol 2017 05 23;37(5):969-975. Epub 2017 Mar 23.

From the Departments of Vascular Medicine (S.J.B.M., S.L.V., L.C.A.S., M.B., S.B., E.S.G.S., J.K.), Experimental Vascular Medicine (J.G.S.), and Nuclear Medicine (H.J.V.), AMC, Amsterdam, The Netherlands; The Copenhagen General Population Study (A.L., B.G.N.) and Department of Clinical Biochemistry (A.L., B.G.N.), Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; and Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, University of Amsterdam, The Netherlands (C.K., C.V.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308834DOI Listing
May 2017

Extent of undertreatment and overtreatment with cholesterol-lowering therapy according to European guidelines in 92,348 Danes without ischemic cardiovascular disease and diabetes in 2004-2014.

Atherosclerosis 2017 02 24;257:9-15. Epub 2016 Nov 24.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.11.025DOI Listing
February 2017

Nonfasting Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis.

JAMA Intern Med 2016 Dec;176(12):1834-1842

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark2Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark3The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark4The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Frederiksberg, Denmark.

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http://dx.doi.org/10.1001/jamainternmed.2016.6875DOI Listing
December 2016

Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology.

J Lipid Res 2016 11 27;57(11):1953-1975. Epub 2016 Sep 27.

Department of Clinical Biochemistry and Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark; and Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1194/jlr.R071233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087876PMC
November 2016

Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply.

Lancet Diabetes Endocrinol 2016 09 23;4(9):730-731. Epub 2016 Jul 23.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, DK-2730 Herlev, Denmark; The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, DK-2730 Herlev, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30147-4DOI Listing
September 2016

PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis.

J Clin Endocrinol Metab 2016 09 24;101(9):3281-7. Epub 2016 May 24.

Department of Clinical Biochemistry (A.L., B.G.N., M.B., P.R.K.) and The Copenhagen General Population Study (A.L., B.G.N., M.B., A.T.-H., P.R.K.), Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark; The Copenhagen City Heart Study (B.G.N., M.B., A.T.-H.), Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Biochemistry (A.T.-H.), Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Faculty of Health and Medical Sciences (A.L., B.G.N., A.T.-H., P.R.K.), University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1210/jc.2016-1206DOI Listing
September 2016

High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study.

Lancet Diabetes Endocrinol 2016 07 13;4(7):577-87. Epub 2016 May 13.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30042-0DOI Listing
July 2016

Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease.

Clin Chem 2016 Apr 17;62(4):593-604. Epub 2016 Feb 17.

Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;

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http://dx.doi.org/10.1373/clinchem.2015.253757DOI Listing
April 2016

How Does Elevated Lipoprotein(a) Cause Aortic Valve Stenosis?

J Am Coll Cardiol 2015 Sep;66(11):1247-1249

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; and the Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jacc.2015.07.045DOI Listing
September 2015

Nonfasting Lipid Profiles: The Way of the Future.

Clin Chem 2015 Sep 23;61(9):1123-5. Epub 2015 Jul 23.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1373/clinchem.2015.243139DOI Listing
September 2015

Elevated Lipoprotein(a) Does Not Cause Low-Grade Inflammation Despite Causal Association With Aortic Valve Stenosis and Myocardial Infarction: A Study of 100,578 Individuals from the General Population.

J Clin Endocrinol Metab 2015 Jul 4;100(7):2690-9. Epub 2015 May 4.

Department of Clinical Biochemistry (A.L., A.V., P.R.K., B.G.N.), and The Copenhagen General Population Study (A.L., A.V., P.R.K., B.G.N.), Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark; The Copenhagen City Heart Study (B.G.N.), Frederiksberg Hospital, Copenhagen University Hospital, 2000 Frederiksberg, Denmark; and Faculty of Health and Medical Sciences (A.L., A.V., P.R.K., B.G.N.), University of Copenhagen, 1165 Copenhagen, Denmark.

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http://dx.doi.org/10.1210/jc.2015-1096DOI Listing
July 2015

Lipoprotein(a): fasting and nonfasting levels, inflammation, and cardiovascular risk.

Atherosclerosis 2014 May 12;234(1):95-101. Epub 2014 Feb 12.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Denmark; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.01.049DOI Listing
May 2014

Nonfasting lipids, lipoproteins, and apolipoproteins in individuals with and without diabetes: 58 434 individuals from the Copenhagen General Population Study.

Clin Chem 2011 Mar 28;57(3):482-9. Epub 2010 Dec 28.

Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev Hospital, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1373/clinchem.2010.157164DOI Listing
March 2011

[Fasting and nonfasting lipids--secondary publication].

Ugeskr Laeger 2009 Jun;171(26):2184-7

Herlev Hospital, Klinisk Biokemisk Afdeling, Herlev.

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June 2009

Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction.

Circulation 2008 Nov 27;118(20):2047-56. Epub 2008 Oct 27.

Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.108.804146DOI Listing
November 2008