Anne E Rosser

Anne E Rosser

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Anne E Rosser

Anne E Rosser

Publications by authors named "Anne E Rosser"

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Insensitivity to loss predicts apathy in huntington's disease.

Mov Disord 2019 Sep 30;34(9):1381-1391. Epub 2019 Jul 30.

Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1002/mds.27787DOI Listing
September 2019

Pluripotent stem cell-derived neurons for transplantation in Huntington's disease.

Prog Brain Res 2017 2;230:263-281. Epub 2017 May 2.

Cardiff University Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff, United Kingdom; Cardiff University School of Biosciences, Cardiff, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.pbr.2017.02.009DOI Listing
May 2018

The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse.

Cell Transplant 2018 02;27(2):230-244

1 Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.

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http://dx.doi.org/10.1177/0963689717744788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898691PMC
February 2018

Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?

Neurochem Int 2017 Jun 27;106:114-121. Epub 2017 Jan 27.

Brain Repair Group, Sir Martin Evans Building, School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK; Wales Brain Repair and Intracranial Neurotherapeutics Unit (B.R.A.I.N), School of Medicine, Cardiff University, Cardiff CF14 4XN, UK; MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2017.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582194PMC
June 2017

Reprogramming the diseased brain.

Nat Biotechnol 2017 05;35(5):426-428

The Brain Repair Group, Cardiff University School of Biosciences, Cardiff, Wales, UK.

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http://dx.doi.org/10.1038/nbt.3869DOI Listing
May 2017

Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function.

Cell Transplant 2016 29;25(4):665-75. Epub 2015 Dec 29.

Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK.

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http://dx.doi.org/10.3727/096368915X690297DOI Listing
December 2016

Human t-DARPP is induced during striatal development.

Neuroscience 2016 10 28;333:320-30. Epub 2016 Jul 28.

Laboratory of Stem Cells and Regenerative Medicine, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain; August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain; Networked Biomedical Research Centre for NeuroDegenerative Disorders (CIBERNED), Spain; Research and Development Unit, Cell Therapy Program, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2016.07.022DOI Listing
October 2016

Can manipulation of differentiation conditions eliminate proliferative cells from a population of ES cell-derived forebrain cells?

Neurogenesis (Austin) 2016 11;3(1):e1127311. Epub 2016 Jan 11.

Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK; Departments of Neurology and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

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https://www.tandfonline.com/doi/full/10.1080/23262133.2015.1
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http://dx.doi.org/10.1080/23262133.2015.1127311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973593PMC
September 2016

Respiratory decline is integral to disease progression in Huntington's disease.

Eur Respir J 2016 08 23;48(2):585-8. Epub 2016 Jun 23.

Neurosciences and Mental Health Institute, Cardiff University, Cardiff, UK Cardiff Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1183/13993003.02215-2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967562PMC
August 2016

In Vivo MRI Evidence that Neuropathology is Attenuated by Cognitive Enrichment in the Yac128 Huntington's Disease Mouse Model.

J Huntingtons Dis 2015 ;4(2):149-60

Brain Repair Group, Life Science Building, 3rd Floor, School of Biosciences, Cardiff University, Museum Avenue, Cardiff, UK.

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http://dx.doi.org/10.3233/JHD-150147DOI Listing
June 2016

Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's disease.

J Neurosci Methods 2016 05 31;265:2-12. Epub 2015 Aug 31.

Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Park Place, Cardiff CF10 3AT, UK; Neuroscience and Mental Health Research Institute, Cardiff University, Hadyn Ellis Building, Cathays, Cardiff CF24 4HQ, UK.

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http://dx.doi.org/10.1016/j.jneumeth.2015.08.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863525PMC
May 2016

Using Actiwatch to monitor circadian rhythm disturbance in Huntington' disease: A cautionary note.

J Neurosci Methods 2016 05 14;265:13-8. Epub 2016 Jan 14.

The Cardiff University Brain Repair Group, Life Sciences Building, School of Biosciences, Museum Avenue, Cardiff CF10 3AX, United Kingdom; Neuroscience and Mental Health Research Institute, Hadyn Ellis Building, Maindy Road, Cathays, Cardiff CF24 4HQ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2016.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863526PMC
May 2016

Neonatal desensitization for the study of regenerative medicine.

Regen Med 2015 ;10(3):265-74

Brain Repair Group, Sir Martin Evans Building, School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, UK.

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http://dx.doi.org/10.2217/rme.14.76DOI Listing
January 2016

Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons.

Mol Ther Methods Clin Dev 2015 16;2:15030. Epub 2015 Sep 16.

Department of Cell Biology, Immunology and Neuroscience, Faculty of Medicine, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), and Networked Biomedical Research Centre for NeuroDegenerative Disorders (CIBERNED), University of Barcelona , Barcelona, Spain.

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http://dx.doi.org/10.1038/mtm.2015.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571731PMC
September 2015

Activin A directs striatal projection neuron differentiation of human pluripotent stem cells.

Development 2015 Apr;142(7):1375-86

Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 ONN, UK Stem Cell Neurogenesis Group, Neuroscience and Mental Health Research Institute, School of Medicine and School of Bioscience, Cardiff University, Cardiff CF24 4HQ, UK

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http://dx.doi.org/10.1242/dev.117093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378247PMC
April 2015

Differentiation of pluripotent stem cells into striatal projection neurons: a pure MSN fate may not be sufficient.

Front Cell Neurosci 2014 2;8:398. Epub 2014 Dec 2.

The Brain Repair Group, School of Biosciences, Cardiff University Cardiff, UK.

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http://dx.doi.org/10.3389/fncel.2014.00398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251433PMC
December 2014

Challenges for taking primary and stem cells into clinical neurotransplantation trials for neurodegenerative disease.

Neurobiol Dis 2014 Jan 18;61:79-89. Epub 2013 May 18.

Brain Repair Group, School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, South Wales, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2013.05.004DOI Listing
January 2014

Is the adult mouse striatum a hostile host for neural transplant survival?

Neuroreport 2013 Dec;24(18):1010-5

aBrain Repair Group, School of Biosciences bSchool of Medicine, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University cSchool of Health Sciences, Cardiff Metropolitan University, Cardiff, UK.

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http://dx.doi.org/10.1097/WNR.0000000000000066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942349PMC
December 2013

Clinical trials of neural transplantation in Huntington's disease.

Prog Brain Res 2012 ;200:345-71

Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK.

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http://dx.doi.org/10.1016/B978-0-444-59575-1.00016-8DOI Listing
November 2013

Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model.

Exp Neurol 2013 Oct 30;248:457-69. Epub 2013 Jul 30.

School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, Wales, UK.

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http://dx.doi.org/10.1016/j.expneurol.2013.07.014DOI Listing
October 2013

A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions.

Brain Res Bull 2012 Jun 20;88(2-3):237-50. Epub 2010 Oct 20.

School of Biosciences, Cardiff University, Wales, UK.

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http://dx.doi.org/10.1016/j.brainresbull.2010.10.005DOI Listing
June 2012

Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats.

Brain Res Bull 2012 Jun 15;88(2-3):251-60. Epub 2011 Apr 15.

School of Biosciences, Cardiff University, Wales, UK.

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http://dx.doi.org/10.1016/j.brainresbull.2011.04.002DOI Listing
June 2012

Long-term expansion of human foetal neural progenitors leads to reduced graft viability in the neonatal rat brain.

Exp Neurol 2012 Jun 23;235(2):563-73. Epub 2012 Mar 23.

Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1016/j.expneurol.2012.03.010DOI Listing
June 2012

Producing striatal phenotypes for transplantation in Huntington's disease.

Exp Biol Med (Maywood) 2012 Apr 4;237(4):343-51. Epub 2012 Apr 4.

Brain Repair Group, School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK.

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http://dx.doi.org/10.1258/ebm.2011.011359DOI Listing
April 2012

Cell-based treatments for huntington's disease.

Int Rev Neurobiol 2011 ;98:483-508

Brain Repair Group, Schools of Biosciences and Medicine, Cardiff University, Cardiff, Wales, UK.

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http://dx.doi.org/10.1016/B978-0-12-381328-2.00017-1DOI Listing
January 2012

Clinical translation of cell transplantation in the brain.

Curr Opin Organ Transplant 2011 Dec;16(6):632-9

School of Biosciences, Cardiff University, Cardiff, South Wales, UK.

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https://insights.ovid.com/crossref?an=00075200-201112000-000
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http://dx.doi.org/10.1097/MOT.0b013e32834c2356DOI Listing
December 2011

Medium spiny neurons for transplantation in Huntington's disease.

Biochem Soc Trans 2009 Feb;37(Pt 1):323-8

Brain Repair Group, School of Biosciences, Museum Avenue, Cardiff University, Cardiff CF10 3AX, Wales, UK.

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http://dx.doi.org/10.1042/BST0370323DOI Listing
February 2009

Use of hand-held dynamometry in the evaluation of lower limb muscle strength in people with Huntington's disease.

J Neurol 2008 Oct 2;255(10):1534-40. Epub 2008 Aug 2.

Department of Physiotherapy, School of Healthcare Studies, Cardiff University, Ty Dewi Sant, Heath Park, Cardiff, CF14 4XN, UK.

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http://dx.doi.org/10.1007/s00415-008-0964-xDOI Listing
October 2008

Potential cellular and regenerative approaches for the treatment of Parkinson's disease.

Neuropsychiatr Dis Treat 2008 Oct;4(5):835-45

Brain Repair Group, School of Biosciences, Cardiff University, CF10 3US, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626922PMC
http://dx.doi.org/10.2147/ndt.s2013DOI Listing
October 2008

Physical therapy intervention for people with Huntington disease.

Phys Ther 2008 Jul 8;88(7):820-31. Epub 2008 May 8.

Department of Physiotherapy, School of Health Care Studies, Cardiff University, Ty Dewi Sant, Heath Park, Cardiff CF14 4XN, Wales, United Kingdom.

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https://academic.oup.com/ptj/article-lookup/doi/10.2522/ptj.
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http://dx.doi.org/10.2522/ptj.20070346DOI Listing
July 2008

Human stem cells for CNS repair.

Cell Tissue Res 2008 Jan 28;331(1):301-22. Epub 2007 Sep 28.

Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3US, UK.

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http://dx.doi.org/10.1007/s00441-007-0488-1DOI Listing
January 2008

Stem cell transplantation for neurodegenerative diseases.

Curr Opin Neurol 2007 Dec;20(6):688-92

Department of Neurology, School of Medicine, Cardiff University, Heath Park, UK.

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http://dx.doi.org/10.1097/WCO.0b013e3282f132fcDOI Listing
December 2007

Striatal graft projections are influenced by donor cell type and not the immunogenic background.

Brain 2007 May 29;130(Pt 5):1317-29. Epub 2007 Mar 29.

Brain Repair Group, School of Biosciences, Museum Avenue, Cardiff, CF10 3US, UK.

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http://dx.doi.org/10.1093/brain/awm053DOI Listing
May 2007

Cell transplantation for Huntington's disease Should we continue?

Brain Res Bull 2007 Apr 10;72(2-3):132-47. Epub 2006 Nov 10.

Cardiff University, Cardiff, Wales, UK.

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http://dx.doi.org/10.1016/j.brainresbull.2006.10.019DOI Listing
April 2007

Stem cell transplantation for Huntington's disease.

Exp Neurol 2007 Feb 8;203(2):279-92. Epub 2007 Jan 8.

The Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK.

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http://dx.doi.org/10.1016/j.expneurol.2006.11.007DOI Listing
February 2007

Cell transplantation for Huntington's disease.

Lancet Neurol 2006 Apr;5(4):284-5

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http://dx.doi.org/10.1016/S1474-4422(06)70385-4DOI Listing
April 2006

Pharmaceutical, cellular and genetic therapies for Huntington's disease.

Clin Sci (Lond) 2006 Jan;110(1):73-88

The Brain Repair Group, School of Biosciences, Cardiff University, Cardiff CF10 3US, UK.

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http://dx.doi.org/10.1042/CS20050148DOI Listing
January 2006

EGF and FGF-2 responsiveness of rat and mouse neural precursors derived from the embryonic CNS.

Brain Res Bull 2005 Dec 21;68(1-2):83-94. Epub 2005 Sep 21.

School of Biosciences, Brain Repair Group, Cardiff University, Biomedical Science Building, Museum Avenue, P.O. Box 911, Cardiff CF1 3US, UK.

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http://dx.doi.org/10.1016/j.brainresbull.2005.08.020DOI Listing
December 2005

Cell therapy in Huntington's disease.

NeuroRx 2004 Oct;1(4):394-405

School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534948PMC
http://dx.doi.org/10.1602/neurorx.1.4.394DOI Listing
October 2004

The effects of various concentrations of FGF-2 on the proliferation and neuronal yield of murine embryonic neural precursor cells in vitro.

Cell Transplant 2003 ;12(3):215-23

Brain Repair Group, School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, UK.

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http://dx.doi.org/10.3727/000000003108746777DOI Listing
April 2004

Neural transplantation in patients with Huntington's disease.

CNS Drugs 2003 ;17(12):853-67

School of Biosciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.2165/00023210-200317120-00001DOI Listing
November 2003

Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson's disease.

Exp Brain Res 2003 Jul 3;151(2):204-17. Epub 2003 Jun 3.

Cambridge Centre for Brain Repair, University of Cambridge, Forvie Site, Robinson Way, CB2 2PY, Cambridge, UK.

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http://dx.doi.org/10.1007/s00221-003-1491-8DOI Listing
July 2003

GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro.

Exp Neurol 2003 Jul;182(1):113-23

Cambridge University Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 2PY, UK.

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http://dx.doi.org/10.1016/s0014-4886(03)00055-4DOI Listing
July 2003

Migration and differentiation of transplanted human neural precursor cells.

Neuroreport 2003 Jul;14(9):1257-62

Cambridge University Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, UK.

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http://dx.doi.org/10.1097/00001756-200307010-00014DOI Listing
July 2003

A case of unilateral neglect in Huntington's disease.

Neurocase 2003 Jun;9(3):261-73

Cambridge Centre for Brain Repair, Cambridge University, Forvie Site, Robinson Way, Cambridge, UK.

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http://dx.doi.org/10.1076/neur.9.3.261.15559DOI Listing
June 2003

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

Brain 2003 May;126(Pt 5):1127-35

MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1093/brain/awg119DOI Listing
May 2003

Verbal fluency in Huntington's disease: a longitudinal analysis of phonemic and semantic clustering and switching.

Neuropsychologia 2002 ;40(8):1277-84

Cambridge Centre for Brain Repair, University of Cambridge, UK.

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http://dx.doi.org/10.1016/s0028-3932(01)00217-2DOI Listing
September 2002

The potential for circuit reconstruction by expanded neural precursor cells explored through porcine xenografts in a rat model of Parkinson's disease.

Exp Neurol 2002 May;175(1):98-111

Cambridge Centre for Brain Repair, University of Cambridge, Forvie Site, Robinson Way, Cambridge, CB2 2PY, United Kingdom.

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http://dx.doi.org/10.1006/exnr.2002.7889DOI Listing
May 2002

Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS.

Eur J Neurosci 2002 Apr;15(7):1255-66

Cambridge Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge CB2 2PY, UK.

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http://dx.doi.org/10.1046/j.1460-9568.2002.01959.xDOI Listing
April 2002