Anne E Kiltie

Anne E Kiltie

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Anne E Kiltie

Anne E Kiltie

Publications by authors named "Anne E Kiltie"

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Mouse Models of Muscle-invasive Bladder Cancer: Key Considerations for Clinical Translation Based on Molecular Subtypes.

Eur Urol Oncol 2019 May 13;2(3):239-247. Epub 2018 Sep 13.

Department of Oncology, CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.euo.2018.08.014DOI Listing
May 2019

Utility of Bladder-Sparing Therapy vs Radical Cystectomy for Muscle-Invasive Bladder Cancer.

JAMA Surg 2019 02;154(2):184-185

CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom.

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2018.4370DOI Listing
February 2019

Neoadjuvant treatment for muscle-invasive bladder cancer: The past, the present, and the future.

Urol Oncol 2018 09 8;36(9):413-422. Epub 2017 Nov 8.

Department of Surgical Oncology (Urology), Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2017.10.014DOI Listing
September 2018

The Impact of Histological Variants of Urothelial Carcinoma on Clinical Outcomes Following Trimodality Bladder-sparing Chemoradiation.

Eur Urol 2017 07 14;72(1):61-63. Epub 2017 Feb 14.

Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1016/j.eururo.2017.01.045DOI Listing
July 2017

No additional prognostic value for MRE11 in squamous cell carcinomas of the anus treated with chemo-radiotherapy.

Br J Cancer 2017 Jul 22;117(3):322-325. Epub 2017 Jun 22.

CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1038/bjc.2017.188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537498PMC
July 2017

E3 Ligase cIAP2 Mediates Downregulation of MRE11 and Radiosensitization in Response to HDAC Inhibition in Bladder Cancer.

Cancer Res 2017 06 31;77(11):3027-3039. Epub 2017 Mar 31.

CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-16-3232DOI Listing
June 2017

Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry.

Authors:
Jonine D Figueroa Candace D Middlebrooks A Rouf Banday Yuanqing Ye Montserrat Garcia-Closas Nilanjan Chatterjee Stella Koutros Lambertus A Kiemeney Thorunn Rafnar Timothy Bishop Helena Furberg Giuseppe Matullo Klaus Golka Manuela Gago-Dominguez Jack A Taylor Tony Fletcher Afshan Siddiq Victoria K Cortessis Charles Kooperberg Olivier Cussenot Simone Benhamou Jennifer Prescott Stefano Porru Colin P Dinney Núria Malats Dalsu Baris Mark P Purdue Eric J Jacobs Demetrius Albanes Zhaoming Wang Charles C Chung Sita H Vermeulen Katja K Aben Tessel E Galesloot Gudmar Thorleifsson Patrick Sulem Kari Stefansson Anne E Kiltie Mark Harland Mark Teo Kenneth Offit Joseph Vijai Dean Bajorin Ryan Kopp Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Silvia Selinski Jan G Hengstler Holger Gerullis Daniel Ovsiannikov Meinolf Blaszkewicz Jose Esteban Castelao Manuel Calaza Maria Elena Martinez Patricia Cordeiro Zongli Xu Vijayalakshmi Panduri Rajiv Kumar Eugene Gurzau Kvetoslava Koppova H Bas Bueno-De-Mesquita Börje Ljungberg Françoise Clavel-Chapelon Elisabete Weiderpass Vittorio Krogh Miren Dorronsoro Ruth C Travis Anne Tjønneland Paul Brennan Jenny Chang-Claude Elio Riboli David Conti Marianna C Stern Malcolm C Pike David Van Den Berg Jian-Min Yuan Chancellor Hohensee Rebecca P Jeppson Geraldine Cancel-Tassin Morgan Roupret Eva Comperat Constance Turman Immaculata De Vivo Edward Giovannucci David J Hunter Peter Kraft Sara Lindstrom Angela Carta Sofia Pavanello Cecilia Arici Giuseppe Mastrangelo Ashish M Kamat Liren Zhang Yilei Gong Xia Pu Amy Hutchinson Laurie Burdett William A Wheeler Margaret R Karagas Alison Johnson Alan Schned G M Monawar Hosain Molly Schwenn Manolis Kogevinas Adonina Tardón Consol Serra Alfredo Carrato Reina García-Closas Josep Lloreta Gerald Andriole Robert Grubb Amanda Black W Ryan Diver Susan M Gapstur Stephanie Weinstein Jarmo Virtamo Christopher A Haiman Maria Teresa Landi Neil E Caporaso Joseph F Fraumeni Paolo Vineis Xifeng Wu Stephen J Chanock Debra T Silverman Ludmila Prokunina-Olsson Nathaniel Rothman

Hum Mol Genet 2016 Mar 4;25(6):1203-14. Epub 2016 Jan 4.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddv492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817084PMC
March 2016

High-throughput DNA Sequencing Identifies Novel Variants in Muscle-invasive Bladder Cancer Patients.

Bladder Cancer 2015 Apr 30;1(1):31-44. Epub 2015 Apr 30.

CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.3233/BLC-150007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218178PMC
April 2015

Deoxycytidine kinase expression underpins response to gemcitabine in bladder cancer.

Clin Cancer Res 2014 Nov 15;20(21):5435-45. Epub 2014 Sep 15.

Department of Oncology, CRUK/MRC Oxford Institute for Radiation Oncology and

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216732PMC
November 2014

Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.

Hum Mol Genet 2014 Oct 26;23(20):5545-57. Epub 2014 May 26.

deCODE Genetics/AMGEN, Reykjavik 101, Iceland Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland

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http://dx.doi.org/10.1093/hmg/ddu264DOI Listing
October 2014

Words of wisdom. Re: Critical analysis of bladder sparing with trimodal therapy in muscle-invasive bladder cancer: a systematic review.

Authors:
Anne E Kiltie

Eur Urol 2014 Sep;66(3):597-8

Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Off Roosevelt Drive, Oxford OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.06.033DOI Listing
September 2014

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours.

Oncotarget 2014 Feb;5(4):993-1003

Gray Institute for Radiation Oncology and Biology, Department of Oncology, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011600PMC
http://dx.doi.org/10.18632/oncotarget.1627DOI Listing
February 2014

Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.

Radiother Oncol 2013 Sep 6;108(3):429-33. Epub 2013 Aug 6.

Gray Institute for Radiation Oncology and Biology, Department of Oncology, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.radonc.2013.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824066PMC
September 2013

The emerging role of histone deacetylase (HDAC) inhibitors in urological cancers.

BJU Int 2013 Apr;111(4):537-42

Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/j.1464-410X.2012.11647.xDOI Listing
April 2013

Imatinib radiosensitizes bladder cancer by targeting homologous recombination.

Cancer Res 2013 Mar 9;73(5):1611-20. Epub 2013 Jan 9.

Sections of Experimental Oncology and Epidemiology and Biostatistics, Leeds Institute of Molecular Medicine, Leeds, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590104PMC
March 2013

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.

Hum Mol Genet 2011 Nov 12;20(21):4268-81. Epub 2011 Jul 12.

deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1093/hmg/ddr303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188988PMC
November 2011

Radiotherapy for node positive penile cancer: experience of the Leeds teaching hospitals.

J Urol 2011 Aug 22;186(2):524-9. Epub 2011 Jun 22.

St. James's Institute of Oncology, Department of Urology, St. James's University Hospital, Leeds, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.juro.2011.03.117DOI Listing
August 2011

In vitro functional effects of XPC gene rare variants from bladder cancer patients.

Carcinogenesis 2011 Apr 27;32(4):516-21. Epub 2011 Jan 27.

Section of Experimental Oncology, Leeds Institute of Molecular Medicine, St James’s University Hospital, Beckett St, Leeds LS9 7TF, UK.

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http://dx.doi.org/10.1093/carcin/bgr005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066418PMC
April 2011

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

Authors:
Nathaniel Rothman Montserrat Garcia-Closas Nilanjan Chatterjee Nuria Malats Xifeng Wu Jonine D Figueroa Francisco X Real David Van Den Berg Giuseppe Matullo Dalsu Baris Michael Thun Lambertus A Kiemeney Paolo Vineis Immaculata De Vivo Demetrius Albanes Mark P Purdue Thorunn Rafnar Michelle A T Hildebrandt Anne E Kiltie Olivier Cussenot Klaus Golka Rajiv Kumar Jack A Taylor Jose I Mayordomo Kevin B Jacobs Manolis Kogevinas Amy Hutchinson Zhaoming Wang Yi-Ping Fu Ludmila Prokunina-Olsson Laurie Burdett Meredith Yeager William Wheeler Adonina Tardón Consol Serra Alfredo Carrato Reina García-Closas Josep Lloreta Alison Johnson Molly Schwenn Margaret R Karagas Alan Schned Gerald Andriole Robert Grubb Amanda Black Eric J Jacobs W Ryan Diver Susan M Gapstur Stephanie J Weinstein Jarmo Virtamo Victoria K Cortessis Manuela Gago-Dominguez Malcolm C Pike Mariana C Stern Jian-Min Yuan David J Hunter Monica McGrath Colin P Dinney Bogdan Czerniak Meng Chen Hushan Yang Sita H Vermeulen Katja K Aben J Alfred Witjes Remco R Makkinje Patrick Sulem Soren Besenbacher Kari Stefansson Elio Riboli Paul Brennan Salvatore Panico Carmen Navarro Naomi E Allen H Bas Bueno-de-Mesquita Dimitrios Trichopoulos Neil Caporaso Maria Teresa Landi Federico Canzian Borje Ljungberg Anne Tjonneland Francoise Clavel-Chapelon David T Bishop Mark T W Teo Margaret A Knowles Simonetta Guarrera Silvia Polidoro Fulvio Ricceri Carlotta Sacerdote Alessandra Allione Geraldine Cancel-Tassin Silvia Selinski Jan G Hengstler Holger Dietrich Tony Fletcher Peter Rudnai Eugen Gurzau Kvetoslava Koppova Sophia C E Bolick Ashley Godfrey Zongli Xu José I Sanz-Velez María D García-Prats Manuel Sanchez Gabriel Valdivia Stefano Porru Simone Benhamou Robert N Hoover Joseph F Fraumeni Debra T Silverman Stephen J Chanock

Nat Genet 2010 Nov 24;42(11):978-84. Epub 2010 Oct 24.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049891PMC
November 2010

Common predisposition alleles for moderately common cancers: bladder cancer.

Authors:
Anne E Kiltie

Curr Opin Genet Dev 2010 Jun 12;20(3):218-24. Epub 2010 Feb 12.

Gray Institute for Radiation Oncology and Biology, Old Road Campus Research Building, Headington, Oxford, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S0959437X100001
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http://dx.doi.org/10.1016/j.gde.2010.01.002DOI Listing
June 2010

A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.

Nat Genet 2010 May 28;42(5):415-9. Epub 2010 Mar 28.

Department of Epidemiology, Biostatistics and Health Technology Assessment, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923020PMC
May 2010

Papillary and muscle invasive bladder tumors with distinct genomic stability profiles have different DNA repair fidelity and KU DNA-binding activities.

Genes Chromosomes Cancer 2009 Apr;48(4):310-21

Cancer Research UK Clinical Centre, Section of Experimental Oncology, Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1002/gcc.20641DOI Listing
April 2009

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.

Nat Genet 2009 Feb 18;41(2):221-7. Epub 2009 Jan 18.

deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525478PMC
February 2009

Molecular epidemiology of DNA repair genes in bladder cancer.

Authors:
Anne E Kiltie

Methods Mol Biol 2009 ;472:281-306

Molecular Radiobiology Group, Cancer Research UK Clinical Centre, St James's University Hospital, West Yorkshire, Leeds, UK.

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http://dx.doi.org/10.1007/978-1-60327-492-0_12DOI Listing
January 2009

Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity.

Mol Cancer Ther 2009 Jan;8(1):203-13

Department of Medical Biophysics, University of Toronto and Radiation Medicine Program, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario, Canada M5G2M9.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0959DOI Listing
January 2009

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.

Nat Genet 2008 Nov 14;40(11):1307-12. Epub 2008 Sep 14.

Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539560PMC
November 2008

Analysis of variants in DNA damage signalling genes in bladder cancer.

BMC Med Genet 2008 Jul 18;9:69. Epub 2008 Jul 18.

Cancer Research UK Clinical Centre, Section of Oncology, Leeds Institute of Molecular Medicine, Leeds, LS9 7TF, UK.

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http://dx.doi.org/10.1186/1471-2350-9-69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488326PMC
July 2008

Similar treatment outcomes for radical cystectomy and radical radiotherapy in invasive bladder cancer treated at a United Kingdom specialist treatment center.

Int J Radiat Oncol Biol Phys 2008 Feb 27;70(2):456-63. Epub 2007 Sep 27.

Pyrah Department of Urology, St. James's University Hospital, The Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.

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http://dx.doi.org/10.1016/j.ijrobp.2007.06.030DOI Listing
February 2008

DNA repair gene XRCC1 polymorphisms and bladder cancer risk.

BMC Genet 2007 Apr 10;8:13. Epub 2007 Apr 10.

Molecular Radiobiology Group, Section of Oncology, Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1186/1471-2156-8-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865553PMC
April 2007

Comprehensive analysis of 22 XPC polymorphisms and bladder cancer risk.

Cancer Epidemiol Biomarkers Prev 2006 Dec;15(12):2537-41

Molecular Radiobiology Group, Cancer Research UK Clinical Centre, St. James's University Hospital, Leeds LS9 7TF, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0288DOI Listing
December 2006

APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer.

Clin Cancer Res 2005 Sep;11(17):6205-11

Cancer Research UK Clinical Centre, St. James's University Hospital, Leeds, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0045DOI Listing
September 2005

DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining.

Nucleic Acids Res 2004 5;32(17):5249-59. Epub 2004 Oct 5.

Cancer Research UK Clinical Centre, St James's University Hospital, Leeds, LS9 7TF, UK.

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http://dx.doi.org/10.1093/nar/gkh842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC521655PMC
October 2004

Development of a rapid, small-scale DNA repair assay for use on clinical samples.

Nucleic Acids Res 2003 Aug;31(15):e83

Cancer Research UK Clinical Centre, St James's University Hospital, Leeds LS9 7TF, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC169971PMC
http://dx.doi.org/10.1093/nar/gng083DOI Listing
August 2003