Anne Brunet

Anne Brunet

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The Genetics of Aging: A Vertebrate Perspective.

Cell 2019 Mar;177(1):200-220

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.02.038DOI Listing
March 2019

Linking Lipid Metabolism to Chromatin Regulation in Aging.

Trends Cell Biol 2019 02 10;29(2):97-116. Epub 2018 Oct 10.

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2018.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340780PMC
February 2019

Turning back time with emerging rejuvenation strategies.

Nat Cell Biol 2019 01 2;21(1):32-43. Epub 2019 Jan 2.

Department of Genetics, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41556-018-0206-0DOI Listing
January 2019

Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma.

Sci Rep 2018 12 10;8(1):17747. Epub 2018 Dec 10.

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, California, 94305, USA.

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http://dx.doi.org/10.1038/s41598-018-35807-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288111PMC
December 2018

The African turquoise killifish: A research organism to study vertebrate aging and diapause.

Aging Cell 2018 06 24;17(3):e12757. Epub 2018 Mar 24.

Department of Genetics, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1111/acel.12757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946070PMC
June 2018

Same path, different beginnings.

Nat Neurosci 2018 02;21(2):159-160

Department of Genetics, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41593-017-0063-3DOI Listing
February 2018

The genome of Austrofundulus limnaeus offers insights into extreme vertebrate stress tolerance and embryonic development.

BMC Genomics 2018 02 20;19(1):155. Epub 2018 Feb 20.

Department of Biology, Center for Life in Extreme Environments, Portland State University, Portland, Oregon, USA.

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http://dx.doi.org/10.1186/s12864-018-4539-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819677PMC
February 2018

The African Turquoise Killifish: A Model for Exploring Vertebrate Aging and Diseases in the Fast Lane.

Cold Spring Harb Symp Quant Biol 2015 7;80:275-9. Epub 2015 Dec 7.

Department of Genetics, Stanford University, Stanford, California 94305 Glenn Laboratories for the Biology of Aging at Stanford, Stanford, California 94305.

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http://dx.doi.org/10.1101/sqb.2015.80.027524DOI Listing
January 2018

Chromatin accessibility dynamics reveal novel functional enhancers in .

Genome Res 2017 12 15;27(12):2096-2107. Epub 2017 Nov 15.

Department of Genetics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1101/gr.226233.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741055PMC
December 2017

Progranulin, lysosomal regulation and neurodegenerative disease.

Nat Rev Neurosci 2017 06 24;18(6):325-333. Epub 2017 Apr 24.

Department of Pathology, University of California San Francisco and Pathology Service 113B, San Francisco VA Medical Center, 513 Parnassus Avenue, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nrn.2017.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040832PMC
June 2017

Interaction between epigenetic and metabolism in aging stem cells.

Curr Opin Cell Biol 2017 04 24;45:1-7. Epub 2017 Jan 24.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA; Glenn Center for the Biology of Aging, Stanford University, USA; Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.

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http://dx.doi.org/10.1016/j.ceb.2016.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482778PMC
April 2017

Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.

Nature 2017 04 5;544(7649):185-190. Epub 2017 Apr 5.

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature21686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391274PMC
April 2017

Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage.

Cell Rep 2017 01;18(3):777-790

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging at Stanford University, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.12.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269583PMC
January 2017

Bursts of Reprogramming: A Path to Extend Lifespan?

Cell 2016 12;167(7):1672-1674

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.11.050DOI Listing
December 2016

Efficient genome engineering approaches for the short-lived African turquoise killifish.

Nat Protoc 2016 Oct 22;11(10):2010-2028. Epub 2016 Sep 22.

Department of Genetics, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nprot.2016.103DOI Listing
October 2016

Characterization of the direct targets of FOXO transcription factors throughout evolution.

Aging Cell 2016 08 8;15(4):673-85. Epub 2016 Apr 8.

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1111/acel.12479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933671PMC
August 2016

FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.

Proc Natl Acad Sci U S A 2016 07 11;113(30):8514-9. Epub 2016 Jul 11.

Institute for Stem Cell Biology and Regenerative Medicine and Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1607079113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968717PMC
July 2016

The Aging Epigenome.

Mol Cell 2016 06;62(5):728-44

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917370PMC
June 2016

AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs.

Trends Cell Biol 2016 Mar 23;26(3):190-201. Epub 2015 Nov 23.

Department of Genetics and the Cancer Biology Program, Stanford University, 300 Pasteur Drive, Stanford, CA, USA.

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http://dx.doi.org/10.1016/j.tcb.2015.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881568PMC
March 2016

Deconstructing Dietary Restriction: A Case for Systems Approaches in Aging.

Cell Metab 2016 Mar;23(3):395-6

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240043PMC
March 2016

High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells.

Genes Dev 2015 Dec 19;29(23):2420-34. Epub 2015 Nov 19.

Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA; Cancer Biology Program, Stanford University School of Medicine, Stanford, California 94305, USA; Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://web.stanford.edu/group/brunet/Pech,%20Garbuzov%20et%2
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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.271783.115
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http://dx.doi.org/10.1101/gad.271783.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691947PMC
December 2015

Lipid Profiles and Signals for Long Life.

Trends Endocrinol Metab 2015 Nov 1;26(11):589-592. Epub 2015 Oct 1.

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging at Stanford, Stanford, CA 94305, USA. Electronic address:

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http://web.stanford.edu/group/brunet/Schroeder%20and%20Brune
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http://linkinghub.elsevier.com/retrieve/pii/S104327601500159
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http://dx.doi.org/10.1016/j.tem.2015.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631627PMC
November 2015

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.

Cell Metab 2015 Nov 8;22(5):907-21. Epub 2015 Oct 8.

Cancer Biology Program, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford, CA 94305, USA. Electronic address:

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http://www.cell.com/cell-metabolism/pdf/S1550-4131(15)00466-
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http://linkinghub.elsevier.com/retrieve/pii/S155041311500466
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http://dx.doi.org/10.1016/j.cmet.2015.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635044PMC
November 2015

Epigenetic regulation of ageing: linking environmental inputs to genomic stability.

Nat Rev Mol Cell Biol 2015 Oct 16;16(10):593-610. Epub 2015 Sep 16.

Department of Genetics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nrm4048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736728PMC
October 2015

Shockingly Early: Chromatin-Mediated Loss of the Heat Shock Response.

Mol Cell 2015 Aug;59(4):515-6

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.08.004DOI Listing
August 2015

AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma.

Cell Rep 2015 Jul 16;12(4):599-609. Epub 2015 Jul 16.

Department of Basic Medical Sciences, Purdue University College of Veterinary Medicine, West Lafayette, IN 47907, USA; Center for Cancer Research, Purdue University College of Veterinary Medicine, West Lafayette, IN 47907, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521589PMC
July 2015

Stem Cell Aging and Sex: Are We Missing Something?

Cell Stem Cell 2015 Jun;16(6):588-90

Department of Genetics, Stanford University, Stanford, CA 94305, USA; The Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA 94305, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909150021
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http://dx.doi.org/10.1016/j.stem.2015.05.006DOI Listing
June 2015

A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

Cell 2015 Feb 12;160(5):1013-1026. Epub 2015 Feb 12.

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging at Stanford, Stanford, CA 94305, USA. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(15)00116-6.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S009286741500116
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http://dx.doi.org/10.1016/j.cell.2015.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344913PMC
February 2015

Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis.

Cell Stem Cell 2015 Jan 13;16(1):39-50. Epub 2014 Nov 13.

Department of Pathology, Stanford University, Stanford, CA 94305, USA; Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389904PMC
January 2015

Cell biology. Lysosomal lipid lengthens life span.

Science 2015 Jan;347(6217):32-3

Department of Genetics, Stanford University, Stanford, CA 94035, USA.

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http://dx.doi.org/10.1126/science.aaa4565DOI Listing
January 2015

H3K4me3 breadth is linked to cell identity and transcriptional consistency.

Cell 2014 Jul;158(3):673-88

Department of Genetics, Stanford University, Stanford CA 94305, USA; Paul F. Glenn Laboratories for the Biology of Aging, Stanford University, Stanford CA 94305, USA; Cancer Biology Program, Stanford University, Stanford CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137894PMC
July 2014

Epigenetics of aging and aging-related disease.

J Gerontol A Biol Sci Med Sci 2014 Jun;69 Suppl 1:S17-20

Department of Cell and Developmental Biology and Penn Epigenetics Program, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1093/gerona/glu042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022130PMC
June 2014

FOXO transcription factors: key regulators of cellular quality control.

Trends Biochem Sci 2014 Apr 13;39(4):159-69. Epub 2014 Mar 13.

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging at Stanford, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2014.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021867PMC
April 2014

FOXO3 promotes quiescence in adult muscle stem cells during the process of self-renewal.

Stem Cell Reports 2014 Apr 20;2(4):414-26. Epub 2014 Mar 20.

Paul F. Glenn Laboratories for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA ; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA ; Neurology Service and Rehabilitation Research and Developmental Center of Excellence, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1016/j.stemcr.2014.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986584PMC
April 2014

Males shorten the life span of C. elegans hermaphrodites via secreted compounds.

Science 2014 Jan 29;343(6170):541-4. Epub 2013 Nov 29.

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/science.1244160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126796PMC
January 2014

Stem cells: Sex specificity in the blood.

Nature 2014 Jan;505(7484):488-90

Department of Genetics, the Cancer Biology Program, and the Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/505488aDOI Listing
January 2014

Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons.

Cell 2013 Oct 24;155(3):621-35. Epub 2013 Oct 24.

Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford University, Stanford, CA 94305, USA; Program in Cancer Biology, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.cell.2013.09.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871197PMC
October 2013

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.

Cell Rep 2013 Jul 27;4(1):189-204. Epub 2013 Jun 27.

The Glenn Laboratories for the Biology of Aging and Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.05.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103025PMC
July 2013

FOXO flips the longevity SWItch.

Nat Cell Biol 2013 May;15(5):444-6

Department of Genetics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ncb2749DOI Listing
May 2013

Bridging the transgenerational gap with epigenetic memory.

Trends Genet 2013 Mar 12;29(3):176-86. Epub 2013 Feb 12.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.tig.2012.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595609PMC
March 2013

Aging and reprogramming: a two-way street.

Curr Opin Cell Biol 2012 Dec 9;24(6):744-56. Epub 2012 Nov 9.

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.ceb.2012.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540161PMC
December 2012

Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate.

J Cell Sci 2012 Dec;125(Pt 23):5597-608

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1242/jcs.114827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575699PMC
December 2012

Prediction of left ventricular ejection fraction 6 months after surgical correction of organic mitral regurgitation: the value of exercise echocardiography and deformation imaging.

Eur Heart J Cardiovasc Imaging 2012 Nov 14;13(11):922-30. Epub 2012 Apr 14.

Department of Cardiology, CIT-IC 804, INSERM U1099 LTSI, Hospital Pontchaillou-University Medical Center, Rue Henri-Le-Guillou, Rennes 35033, France.

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https://academic.oup.com/ehjcimaging/article-lookup/doi/10.1
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http://dx.doi.org/10.1093/ehjci/jes068DOI Listing
November 2012

[Aging and the control of the insulin-FOXO signaling pathway].

Authors:
Anne Brunet

Med Sci (Paris) 2012 Mar 6;28(3):316-20. Epub 2012 Apr 6.

Département de génétique, Stanford University, 94305 Stanford, CA, États-Unis.

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http://dx.doi.org/10.1051/medsci/2012283021DOI Listing
March 2012

Histone methylation makes its mark on longevity.

Trends Cell Biol 2012 Jan 15;22(1):42-9. Epub 2011 Dec 15.

Department of Genetics, 300 Pasteur Drive, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.tcb.2011.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253950PMC
January 2012

Epigenetic memory of longevity in Caenorhabditis elegans.

Worm 2012 Jan;1(1):77-81

Department of Genetics; Stanford University; Stanford, CA USA.

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http://dx.doi.org/10.4161/worm.19157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670177PMC
January 2012

The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.

Aging Cell 2011 Dec 16;10(6):980-90. Epub 2011 Sep 16.

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2011.00738.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215905PMC
December 2011

Transposon-Mediated Transgenesis in the Short-Lived African Killifish Nothobranchius furzeri, a Vertebrate Model for Aging.

G3 (Bethesda) 2011 Dec 1;1(7):531-8. Epub 2011 Dec 1.

Department of Genetics, Stanford University, Stanford, California 94305.

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http://dx.doi.org/10.1534/g3.111.001271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276177PMC
December 2011

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans.

Nature 2011 Oct 19;479(7373):365-71. Epub 2011 Oct 19.

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature10572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368121PMC
October 2011

A CRTCal link between energy and life span.

Authors:
Anne Brunet

Cell Metab 2011 Apr;13(4):358-360

Department of Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://web.stanford.edu/group/brunet/Brunet%202011.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S155041311100099
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http://dx.doi.org/10.1016/j.cmet.2011.03.012DOI Listing
April 2011

Energy metabolism in adult neural stem cell fate.

Prog Neurobiol 2011 Feb 5;93(2):182-203. Epub 2010 Nov 5.

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.pneurobio.2010.10.007DOI Listing
February 2011

The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation.

Aging (Albany NY) 2011 Feb;3(2):108-24

Department of Genetics, Stanford University School of Medicine; Stanford, CA 94305, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082007PMC
http://dx.doi.org/10.18632/aging.100285DOI Listing
February 2011

Autoimmune hypoparathyroidism in a 12-year-old girl with McKusick cartilage hair hypoplasia.

Pediatr Nephrol 2009 Dec 22;24(12):2449-53. Epub 2009 Jul 22.

Service de Néphrologie et Rhumatologie Pédiatriques, Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, 59 Bd Pinel, 69677 Bron Cedex, France.

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http://link.springer.com/10.1007/s00467-009-1256-0
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http://dx.doi.org/10.1007/s00467-009-1256-0DOI Listing
December 2009

AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity.

Ann N Y Acad Sci 2009 Jul;1170:688-92

Department of Genetics, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04019.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814416PMC
July 2009

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans.

Aging Cell 2009 Apr 23;8(2):113-27. Epub 2009 Feb 23.

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2009.00459.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680339PMC
April 2009

Cancer: When restriction is good.

Authors:
Anne Brunet

Nature 2009 Apr;458(7239):713-4

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http://dx.doi.org/10.1038/458713aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822621PMC
April 2009

FoxO transcription factors in the maintenance of cellular homeostasis during aging.

Curr Opin Cell Biol 2008 Apr 3;20(2):126-36. Epub 2008 Apr 3.

Department of Genetics, Stanford University, Stanford, CA 94305, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387118PMC
April 2008

Signaling networks in aging.

J Cell Sci 2008 Feb;121(Pt 4):407-12

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

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February 2008

Sarcoidosis-like reaction related to Propionibacterium acnes and immune restoration syndrome in HIV infection .

J Rheumatol 2007 Dec;34(12):2495-6

Department of Internal Medicine, Centre national de référence pour les vascularites et la sclérodermie, Hôpital Cochin, Université Paris-Descartes, Paris, France.

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December 2007

Aging and cancer: killing two birds with one worm.

Authors:
Anne Brunet

Nat Genet 2007 Nov;39(11):1306-7

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http://dx.doi.org/10.1038/ng1107-1306DOI Listing
November 2007

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor.

J Biol Chem 2007 Oct 20;282(41):30107-19. Epub 2007 Aug 20.

Department of Genetics, Stanford University, Stanford, California 94305, USA.

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October 2007

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans.

Curr Biol 2007 Oct 27;17(19):1646-56. Epub 2007 Sep 27.

Department of Genetics, Cancer Biology Program, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1016/j.cub.2007.08.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185793PMC
October 2007

Ageing: from stem to stern.

Nature 2007 Sep;449(7160):288-91

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September 2007

FOXO transcription factors.

Curr Biol 2007 Feb;17(4):R113-4

Department of Genetics and Neurosciences Program, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA.

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February 2007

FOXO transcription factors at the interface between longevity and tumor suppression.

Oncogene 2005 Nov;24(50):7410-25

Department of Genetics, Stanford University, CA 94305, USA.

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November 2005

[The multiple roles of FOXO transcription factors].

Authors:
Anne Brunet

Med Sci (Paris) 2004 Oct;20(10):856-9

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October 2004

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase.

Science 2004 Mar 19;303(5666):2011-5. Epub 2004 Feb 19.

Division of Neuroscience, Children's Hospital, and Department of Neurobiology, Center for Blood Research (CBR) Institute for Biomedical Research, Harvard Medical School, Boston, MA 02115, USA.

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March 2004

PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation.

J Biol Chem 2003 Dec 23;278(52):52587-97. Epub 2003 Sep 23.

Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

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December 2003

The many forks in FOXO's road.

Sci STKE 2003 Mar 4;2003(172):RE5. Epub 2003 Mar 4.

Department of Neurobiology, Division of Neuroscience, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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March 2003

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein.

Science 2002 Apr;296(5567):530-4

Division of Neuroscience, Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.

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April 2002

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport.

J Cell Biol 2002 Mar 25;156(5):817-28. Epub 2002 Feb 25.

Center for Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173313PMC
March 2002