Publications by authors named "Anne B Young"

43 Publications

Sex may influence motor phenotype in a novel rodent model of cerebral palsy.

Neurobiol Dis 2020 02 10;134:104711. Epub 2019 Dec 10.

Harvard Medical School, Boston, MA, USA; Beth Israel Deaconess Medical Center, Boston, MA, USA.

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February 2020

Sex may influence motor phenotype in a novel rodent model of cerebral palsy.

Neurobiol Dis 2020 02 10;134:104711. Epub 2019 Dec 10.

Harvard Medical School, Boston, MA, USA; Beth Israel Deaconess Medical Center, Boston, MA, USA.

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February 2020

Phenotype-genotype discrepancies in the prospective Huntington at-risk observational study.

Ann Clin Transl Neurol 2019 Jun 1;6(6):1046-1052. Epub 2019 May 1.

Massachusetts General Hospital Boston Massachusetts.

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June 2019

LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington's Disease.

J Huntingtons Dis 2016 12;5(4):347-355

Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.

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December 2016

LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington's Disease.

J Huntingtons Dis 2016 12;5(4):347-355

Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.

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December 2016

HTRF analysis of soluble huntingtin in PHAROS PBMCs.

Neurology 2013 Sep 21;81(13):1134-40. Epub 2013 Aug 21.

From the Massachusetts General Hospital (M.M.-L., R.E.G., J.J.R., H.D.R., S.M., A.B.Y., S.M.H.), MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Charlestown, MA; University of Rochester Medical Center (S.E., D.O.), Department of Biostatistics and Computational Biology, Rochester, NY; Veterans Administration Hospital (W.M.), Bedford, MA; and Program for Regulatory Science & Medicine (I.S.), Georgetown University, Washington, DC.

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September 2013

Native mutant huntingtin in human brain: evidence for prevalence of full-length monomer.

J Biol Chem 2012 Apr 27;287(16):13487-99. Epub 2012 Feb 27.

Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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April 2012

Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons.

J Neurosci Methods 2012 Mar 2;204(2):221-6. Epub 2011 Dec 2.

Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, 114 16th Street B114-2000, Boston, MA 02129, United States.

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March 2012

Milestones in huntington disease.

Mov Disord 2011 May;26(6):1127-33

Program for Regulatory Science and Medicine, Georgetown University, Washington, District of Columbia, USA.

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May 2011

Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats.

PLoS One 2010 Nov 10;5(11):e13861. Epub 2010 Nov 10.

Neurology Department, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America.

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November 2010

Four decades of neurodegenerative disease research: how far we have come!

Authors:
Anne B Young

J Neurosci 2009 Oct;29(41):12722-8

Neurology Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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October 2009

Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5.

J Neurochem 2009 Jul 30;110(2):557-69. Epub 2009 Apr 30.

Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, 02129, USA.

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July 2009

Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy.

Proc Natl Acad Sci U S A 2009 Feb 26;106(8):2892-6. Epub 2009 Jan 26.

Department of Brain and Cognitive Sciences and the McGovern Institute for Brain Research, Massachusetts Institute of Technology, 43 Vassar Street, Cambridge, MA 02139, USA.

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February 2009

A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse.

Proc Natl Acad Sci U S A 2007 Oct 9;104(42):16685-9. Epub 2007 Oct 9.

Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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October 2007

Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells.

Chem Biol 2006 Jul;13(7):765-70

Massachusetts General Institute for Neurodegenerative Disease and Harvard Medical School, Department of Neurology, Massachusetts General Hospital, Charlestown, 02129, USA.

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July 2006

Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases.

Proc Natl Acad Sci U S A 2006 Mar 6;103(11):4246-51. Epub 2006 Mar 6.

Center for Cancer Research, Massachusetts Institute of Technology, Room E18-505, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

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March 2006

Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice.

J Neurosci 2005 Nov;25(45):10414-9

MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02129, USA.

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November 2005