Publications


Relationship between sensorimotor peripheral nerve function and indicators of cardiovascular autonomic function in older adults from the Health, Aging and Body Composition Study.
Exp Gerontol 2017 Oct 22;96:38-45. Epub 2017 Apr 22.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 N. Bellefield Ave., 5th Floor, Pittsburgh, PA 15213, United States. Electronic address:



Impact of Incident Heart Failure on Body Composition Over Time in the Health, Aging, and Body Composition Study Population.
Circ Heart Fail 2017 Sep;10(9)
From the Section of Geriatric Cardiology, University of Pittsburgh Medical Center, Geriatric Research, Education, and Clinical Center, VA Pittsburgh Healthcare System (D.E.F.), Department of Epidemiology, Center for Aging and Population Health (A.J.S.), Department of Epidemiology, Graduate School of Public Health (R.B.), and Epidemiology, Medicine, and Clinical and Translational Science Institute (A.B.N.), University of Pittsburgh, PA; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, MD (T.H.); Division of General Internal Medicine, University of California in San Francisco (A.M.K.); Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis (S.S.); Intramural Research Program, National Institute on Aging, Baltimore, MD (E.M.S.); Division of Cardiology, Stony Brook University, NY (J.B.); and Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY (J.R.K.).

A novel healthy blood pressure phenotype in the Long Life Family Study.
J Hypertens 2017 Aug 23. Epub 2017 Aug 23.
aDepartment of Epidemiology bDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA cDepartment of Public Health, The Danish Aging Research Center, University of Southern Denmark, Odense, Denmark dTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University Medical Center, New York, New York eDivision of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri fDepartment of Medicine, Geriatrics Section, Boston Medical Center, Boston University School of Medicine gDepartment of Biostatistics, Boston University, Boston, Massachusetts hCenter for Population Health and Aging, Department of Sociology, Duke University, Durham, North Carolina iDepartments of Medicine and Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility.
J Am Geriatr Soc 2017 Jul 21;65(7):1427-1433. Epub 2017 Feb 21.
Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

Factors Associated With Ischemic Stroke Survival and Recovery in Older Adults.
Stroke 2017 Jul 19;48(7):1818-1826. Epub 2017 May 19.
From the School of Biological and Population Health Sciences, Oregon State University, Corvallis (D.T.W., M.C.O.); School of Medicine, Oregon Health and Science University, Portland (D.T.W.); Department of Neurology (W.T.L.), and Department of Biostatistics (A.M.A.), University of Washington, Seattle; Department of Oncology, John Hopkins University, Baltimore, MD (R.V.); Department of Public Health Sciences, University of Miami, Coral Gables, FL (A.Z.A.H.); Department of Pathology and Laboratory Medicine, and Department of Medicine, University of Vermont, Burlington (M.C.); and Department of Epidemiology, University of Pittsburgh, PA (A.B.N.).

Association of Blood Pressure Trajectory With Mortality, Incident Cardiovascular Disease, and Heart Failure in the Cardiovascular Health Study.
Am J Hypertens 2017 Jun;30(6):587-593
Kidney Health Research Collaborative, Division of Nephrology, Department of Medicine, University of California, San Francisco, California, USA.

Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Hum Mol Genet 2017 Jun;26(11):2156-2163
Nephrology Section, Veterans Affairs San Diego Healthcare System, University of California San Diego, San Diego, CA 92161, USA & Divisions of Nephrology and Preventive Medicine, Department of Medicine, University of California San Diego School of Medicine, San Diego, CA 92161, USA.







Arterial Stiffness and Risk of Overall Heart Failure, Heart Failure With Preserved Ejection Fraction, and Heart Failure With Reduced Ejection Fraction: The Health ABC Study (Health, Aging, and Body Composition).
Hypertension 2017 Feb 19;69(2):267-274. Epub 2016 Dec 19.
From the Division of Cardiology, Department of Internal Medicine (A.P., J.D.B.) and Department of Clinical Sciences (J.D.B.), University of Texas Southwestern Medical Center, Dallas; Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA (H.K.); Department of Epidemiology, Graduate School of Public Health at University of Pittsburgh, PA (A.B.N.); Laboratory of Cardiovascular Science, Biomedical Research Center, National Institutes of Heath, National Institute of Aging, Baltimore, MD (E.G.L.); Section of Geriatric Cardiology, Divisions of Geriatrics and Cardiology, University of Pittsburgh School of Medicine, VA Pittsburgh Healthcare System, PA (D.E.F.); and Division of Cardiology, Department of Internal Medicine, Stony Brook University School of Medicine, New York, NY (J.B.).



An Evaluation of the Longitudinal, Bidirectional Associations Between Gait Speed and Cognition in Older Women and Men.
J Gerontol A Biol Sci Med Sci 2016 Dec 10;71(12):1616-1623. Epub 2016 Apr 10.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.

Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial.
Ann Intern Med 2016 Dec 27;165(12):833-840. Epub 2016 Sep 27.
From Yale School of Medicine, New Haven, Connecticut; University of Maryland School of Medicine, Baltimore, Maryland; University of Florida, Gainesville, Florida; Pennington Biomedical Research Center, Baton Rouge, Louisiana; Tufts University, Boston, Massachusetts; Stanford School of Medicine, Stanford, California; Wake Forest University and Wake Forest School of Medicine, Winston-Salem, North Carolina; University of Pittsburgh, Pittsburgh, Pennsylvania; and Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.
Circ Cardiovasc Genet 2016 Dec 21;9(6):511-520. Epub 2016 Nov 21.

Effect of Statin Use on Mobility Disability and its Prevention in At-risk Older Adults: The LIFE Study.
J Gerontol A Biol Sci Med Sci 2016 Nov 17;71(11):1519-1524. Epub 2016 Mar 17.
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Areal and volumetric bone mineral density and risk of multiple types of fracture in older men.
Bone 2016 Nov 20;92:100-106. Epub 2016 Aug 20.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

Slow gait, white matter characteristics, and prior 10-year interleukin-6 levels in older adults.
Neurology 2016 Nov 12;87(19):1993-1999. Epub 2016 Oct 12.
From the Division of Geriatric Medicine and Gerontology, Department of Medicine (N.K.N.), Department of Neurology (O.L.L.) and the Pittsburgh Alzheimer's Disease Research Center (O.L.L., N.K.N.), University of Pittsburgh School of Medicine, and Department of Epidemiology, Graduate School of Public Health (R.M.B., G.L., A.B.N., C.R.), University of Pittsburgh, PA; Sticht Center on Aging (S.K.), Wake Forest School of Medicine, Winston-Salem, NC; Department of Psychiatry (K.Y.), University of California at San Francisco; and the Longitudinal Studies Section (S.A.S.), Translational Gerontology Branch, National Institute on Aging, Baltimore, MD.

Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study.
J Am Geriatr Soc 2016 Nov 26;64(11):e189-e194. Epub 2016 Oct 26.
Department of Medicine, School of Medicine and Geriatric Section, Boston University, Boston Medical Center, Boston, Massachusetts.

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.
J Clin Endocrinol Metab 2016 Nov 7;101(11):4270-4282. Epub 2016 Sep 7.
Departments of Internal Medicine (R.P.P., L.C., M.M.) and Epidemiology (R.P.P., O.H.F., A.D., A.H., A.I., L.C., M.L.P.P.), Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands; Rotterdam Thyroid Center (R.P.P., L.C., M.M.) and Department of Radiology and Neurology (M.A.I.), Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands; Department of General Internal Medicine (N.R., C.B., M.R.B.), Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; Service of Endocrinology, Diabetes, and Metabolism (T.-H.C.), University Hospital of Lausanne, 1011 Lausanne, Switzerland; Departments of Clinical Chemistry and Laboratory Medicine (W.P.J.d.E.), Public Health and Primary Care (J.G.), and Cardiology (W.J.), Leiden University Medical Center, 2300 RC Leiden, The Netherlands; Departments of Medicine and Epidemiology and Biostatistics (D.C.B.), University of California, San Francisco, San Francisco, California 94143; Division of Endocrinology, Diabetes, and Metabolism (A.R.C.), Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Epidemiology (A.H.), Harvard T. H. Chan School of Public Health, Boston, Massachusetts 02115; Department of Endocrinology (S.R.), Gateshead Health Foundation National Health Service Trust, Gateshead, SE18 4QH, United Kingdom; Department of Endocrinology and Diabetes (J.P.W.), Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia; Schools of Medicine and Pharmacology (J.P.W.) and Population Health (A.B.), University of Western Australia, Crawley, Western Australia 6009, Australia; National Council Research Institute of Clinical Physiology (G.I.), 56124 Pisa, Italy; Robertson Centre for Biostatistics (I.F.) and Institute of Cardiovascular and Medical Sciences (D.J.S.), Faculty of Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom; Department of Epidemiology (A.B.N.), University of Pittsburgh, Pittsburgh, Pennsylvania 15260; Department of Internal Medicine (S.J.L.B., R.P.D.), University Medical Center, University of Groningen, 9700 AB Groningen, The Netherlands; Department of Medicine (C.W., C.D.), Division of Nephrology, University Hospital of Würzburg, and Comprehensive Heart Failure Centre (C.W., C.D.), 97070 Würzburg, Germany; Department of Clinical Studies (M.I.), Radiation Effects Research Foundation, Nagasaki 850-8555, Japan; Department of Clinical and Experimental Medicine (G.C.), University of Parma, 143100 Parma, Italy; National Institute on Aging (L.F.), Baltimore, Maryland 21225; Institute for Community Medicine (H.V.), Clinical-Epidemiological Research/Study of Health in Pomerania, University Medicine, German Centre of Cardiovascular Research, Partner Site, Department of Internal Medicine (M.D.), and University Medicine (M.D.), German Centre of Cardiovascular Research, Partner Site, 17487 Greifswald, Germany; Departments of Neurology and Epidemiology (W.T.L.), and Cardiovascular Health Research Unit (W.T.L.), Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington 98108; Group Health Research Institute (B.M.P.), Group Health Cooperative, Seattle, Washington 98101; Division of Endocrinology (R.M.B.M., J.A.S.), Department of Medicine, Federal University of Sao Paulo, 05508-900 São Paulo, Brazil; Division of Endocrinology (J.A.S.), Faculdade de Medicina de Marília, Marília, Brazil; Department of Public Health and Primary Care (R.N.L., K.-T.K.), University of Cambridge, Cambridge CB2 1TN, United Kingdom; Interuniversity Cardiology Institute of The Netherlands (W.J.), 3508 GA Utrecht, The Netherlands; School of Clinical and Experimental Medicine (J.A.F.), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; and Department of Public Health and Center for Healthy Ageing (R.G.W.), Faculty of Health and Medical Sciences, University of Copenhagen, DK-2400 Copenhagen, Denmark.


Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
Aging Cell 2016 Oct 21;15(5):811-24. Epub 2016 Jun 21.
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.



The relationship between mitochondrial function and walking performance in older adults with a wide range of physical function.
Exp Gerontol 2016 Aug 12;81:1-7. Epub 2016 Apr 12.
Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, United States. Electronic address:

Commentary: Life course epidemiology: the past two decades and future directions.
Int J Epidemiol 2016 Aug;45(4):1013-1015
Department of Epidemiology Katherine M. Detre Endowed Chair of Population Health Sciences Director, Center for Aging and Population Health, Professor of Epidemiology, Medicine, and Clinical and Translational Science Graduate School of Public, Health University of Pittsburgh, A527 Crabtree Hall, 130 DeSoto Street Pittsburgh, PA 15261. E-mail:

A Multidimensional Risk Score to Predict All-Cause Hospitalization in Community-Dwelling Older Individuals With Obstructive Lung Disease.
J Am Med Dir Assoc 2016 Jun 23;17(6):508-13. Epub 2016 Feb 23.
NUTRIM School for Nutrition and Translational Research in Metabolism, Department of Respiratory Medicine, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Impact of Drug-Drug and Drug-Disease Interactions on Gait Speed in Community-Dwelling Older Adults.
Drugs Aging 2016 Jun;33(6):411-8
Division of Geriatrics, Department of Medicine, School of Medicine, University of Pittsburgh, Kaufmann Medical Building, Suite 500, 3471 Fifth Avenue, Pittsburgh, PA, 15213, USA.


Lipoprotein-Associated Phospholipase A2 and Incident Peripheral Arterial Disease in Older Adults: The Cardiovascular Health Study.
Arterioscler Thromb Vasc Biol 2016 Apr 4;36(4):750-6. Epub 2016 Feb 4.
From the Division of Cardiology, University of Southern California Keck School of Medicine, Los Angeles (P.K.G.); Department of Biostatistics, University of Washington, Seattle (A.M.A., K.D.H.S.); Glaxo Smith Kline, Collegeville, PA (C.K.); Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington (N.S.J., M.C.); Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA (K.J.M.); Department of Family and Preventive Medicine, University of California in San Diego School of Medicine, La Jolla (M.H.C.); Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC (C.D.F.); Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA (A.B.N.); and Department of Medicine, Cardiovascular Research Institute, University of Vermont College of Medicine, Burlington (M.C.).

Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.
BMC Geriatr 2016 Apr 9;16:80. Epub 2016 Apr 9.
Center for Genome Sciences and Systems Biology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8116, St. Louis, MO, 63108, USA.


Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life.
J Gerontol A Biol Sci Med Sci 2016 Feb 20;71(2):221-7. Epub 2015 Sep 20.
Department of Epidemiology and Biostatistics, University of California, San Francisco. Department of Neurology and Department of Psychiatry, University of California, San Francisco.

Bicarbonate Concentration, Acid-Base Status, and Mortality in the Health, Aging, and Body Composition Study.
Clin J Am Soc Nephrol 2016 Feb 14;11(2):308-16. Epub 2016 Jan 14.
Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.


Embedding clinical interventions into observational studies.
Contemp Clin Trials 2016 Jan 2;46:100-105. Epub 2015 Dec 2.
Center for Heart & Vascular Health, Christiana Care Health System, 4755 Ogletown-Stanton Road, Suite 1070, Newark, DE 19713, USA. Electronic address:

Association of Serum Erythropoietin With Cardiovascular Events, Kidney Function Decline, and Mortality: The Health Aging and Body Composition Study.
Circ Heart Fail 2016 Jan;9(1):e002124
From the Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, MA (P.S.G., M.J.S.); Kidney Research Institute (R.K.) and Department of Anesthesiology and Pain Medicine (K.V.P.), University of Washington, Seattle; Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, NC (S.B.K.); Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT (C.R.P.); Nephrology Section, Veterans Affairs San Diego Healthcare System and Division of Nephrology and Preventive Medicine, University of California, San Diego (J.H.I.); Renal Section, VA Pittsburgh Healthcare System (L.F.F.) and Department of Epidemiology, Graduate School of Public Health (A.B.N.), University of Pittsburgh, PA; Department of Epidemiology, Biostatistics, and Medicine, University of California, San Francisco (M.G.S.); Department of General Internal Medicine, San Francisco VA Medical Center, CA (M.G.S.); and Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MA (T.B.H.).



Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Nat Genet 2015 Nov 28;47(11):1294-1303. Epub 2015 Sep 28.
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.

Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults.
Am Heart J 2015 Sep 14;170(3):498-505.e2. Epub 2015 Jun 14.
Cardiology Section, Whitaker Cardiovascular Institute, Evans Department of Medicine, Boston University School of Medicine, Boston, MA; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA. Electronic address:

OF