Anna Teti

Anna Teti

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Anna Teti

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CRELD2 is a novel LRP1 chaperone that regulates non-canonical WNT signalling in skeletal development.

J Bone Miner Res 2020 Mar 17. Epub 2020 Mar 17.

Biosciences Institute, Newcastle University, International Centre for Life, NE1 3BZ, Newcastle, Upon Tyne, UK.

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http://dx.doi.org/10.1002/jbmr.4010DOI Listing
March 2020

Extracellular Vesicles From Osteotropic Breast Cancer Cells Affect Bone Resident Cells.

J Bone Miner Res 2020 Feb 5;35(2):396-412. Epub 2019 Nov 5.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jbmr.3891DOI Listing
February 2020

Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries.

J Sci Med Sport 2019 Nov 29;22(11):1219-1225. Epub 2019 Jul 29.

Division of Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.jsams.2019.07.012DOI Listing
November 2019

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry.

Br J Cancer 2019 07 26;121(2):157-171. Epub 2019 Jun 26.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila Via Vetoio - Coppito 2, 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1038/s41416-019-0501-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738045PMC
July 2019

Isolation and Generation of Osteoclasts.

Methods Mol Biol 2019 ;1914:3-19

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://link.springer.com/10.1007/978-1-4939-8997-3_1
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http://dx.doi.org/10.1007/978-1-4939-8997-3_1DOI Listing
June 2019

Apoptosis-associated speck-like protein containing a caspase-1 recruitment domain (ASC) contributes to osteoblast differentiation and osteogenesis.

J Cell Physiol 2019 04 31;234(4):4140-4153. Epub 2018 Aug 31.

Laboratório de Bioensaios e Dinâmica Celular, Department of Chemistry and Biochemistry, Bioscience Institute, Universidade Estadual Paulista, UNESP, campus Botucatu, Rubião Junior, Botucatu, Sao Paulo, Brazil.

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http://dx.doi.org/10.1002/jcp.27226DOI Listing
April 2019

Osteoblasts Regulate Angiogenesis in Response to Mechanical Unloading.

Calcif Tissue Int 2019 03 21;104(3):344-354. Epub 2018 Nov 21.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, via Vetoio - Coppito 2, 67100, L'aquila, Italy.

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http://dx.doi.org/10.1007/s00223-018-0496-zDOI Listing
March 2019

Congenital disorders of bone and blood.

Bone 2019 02 6;119:71-81. Epub 2018 Mar 6.

Department of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Division of Anatomic and Molecular Pathology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.bone.2018.03.002DOI Listing
February 2019

A Complex Role for Lipocalin 2 in Bone Metabolism: Global Ablation in Mice Induces Osteopenia Caused by an Altered Energy Metabolism.

J Bone Miner Res 2018 06 24;33(6):1141-1153. Epub 2018 Mar 24.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jbmr.3406DOI Listing
June 2018

RNA interference therapy for autosomal dominant osteopetrosis type 2. Towards the preclinical development.

Bone 2018 05 6;110:343-354. Epub 2018 Mar 6.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio - Coppito 2, 67100 L'Aquila, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2018.02.031DOI Listing
May 2018

Osteoblast-Derived Extracellular Vesicles Are Biological Tools for the Delivery of Active Molecules to Bone.

J Bone Miner Res 2018 03 11;33(3):517-533. Epub 2017 Dec 11.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jbmr.3332DOI Listing
March 2018

Osteomimicry: How the Seed Grows in the Soil.

Calcif Tissue Int 2018 02 16;102(2):131-140. Epub 2017 Nov 16.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio - Coppito 2, 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1007/s00223-017-0365-1DOI Listing
February 2018

The "love-hate" relationship between osteoclasts and bone matrix.

Matrix Biol 2016 May-Jul;52-54:176-190. Epub 2016 Feb 26.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.02.009DOI Listing
December 2017

Osteopetroses, emphasizing potential approaches to treatment.

Bone 2017 Sep 4;102:50-59. Epub 2017 Feb 4.

Department of Medicine, Indiana University, 1120 W. Michigan St., Indianapolis, IN 46202, USA; Department of Medical and Molecular Genetics, Indiana University, 1120 W. Michigan St., Indianapolis, IN 46202, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282173004
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http://dx.doi.org/10.1016/j.bone.2017.02.002DOI Listing
September 2017

Non-conventional role of haemoglobin beta in breast malignancy.

Br J Cancer 2017 Sep 3;117(7):994-1006. Epub 2017 Aug 3.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1038/bjc.2017.247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625664PMC
September 2017

Interleukin-1β, lipocalin 2 and nitric oxide synthase 2 are mechano-responsive mediators of mouse and human endothelial cell-osteoblast crosstalk.

Sci Rep 2016 07 19;6:29880. Epub 2016 Jul 19.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, via Vetoio - Coppito 2, 67100 L' Aquila, Italy.

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http://dx.doi.org/10.1038/srep29880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949438PMC
July 2016

Recent advances in mesenchymal stem cell immunomodulation: the role of microvesicles.

Cell Transplant 2015 21;24(2):133-49. Epub 2013 Nov 21.

Research Laboratories, Bambino Gesù Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.3727/096368913X675728DOI Listing
November 2015

Effective Small Interfering RNA Therapy to Treat CLCN7-dependent Autosomal Dominant Osteopetrosis Type 2.

Mol Ther Nucleic Acids 2015 Sep 1;4:e248. Epub 2015 Sep 1.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1038/mtna.2015.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877447PMC
September 2015

Gut microbiota-derived outer membrane vesicles: under-recognized major players in health and disease?

Discov Med 2015 May;19(106):343-8

Department of Women's and Children's Health, University of Padova, 35128 Padova, Italy.

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May 2015

Biotechnological approach for systemic delivery of membrane Receptor Activator of NF-κB Ligand (RANKL) active domain into the circulation.

Biomaterials 2015 Apr 17;46:58-69. Epub 2015 Jan 17.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio - Coppito 2, 67100 L'Aquila, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612140128
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http://dx.doi.org/10.1016/j.biomaterials.2014.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337851PMC
April 2015

Lipocalin 2: a new mechanoresponding gene regulating bone homeostasis.

J Bone Miner Res 2015 Feb;30(2):357-68

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jbmr.2341DOI Listing
February 2015

Bone, a dynamic and integrating tissue.

Arch Biochem Biophys 2014 Nov 23;561:1-2. Epub 2014 Aug 23.

Laboratory for Bioassays and Cellular Dynamics, São Paulo State University - UNESP, Bioscience Institute, Department of Chemistry and Biochemistry, Rubião Junior S/N, PO Box 510, CEP: 18618-970 Botucatu, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2014.08.012DOI Listing
November 2014

Reprint of: The Great Beauty of the osteoclast.

Arch Biochem Biophys 2014 Nov;561:13-21

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2014.08.009DOI Listing
November 2014

Kinome profiling of osteoblasts on hydroxyapatite opens new avenues on biomaterial cell signaling.

Biotechnol Bioeng 2014 Sep 11;111(9):1900-5. Epub 2014 Jun 11.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://doi.wiley.com/10.1002/bit.25246
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http://dx.doi.org/10.1002/bit.25246DOI Listing
September 2014

The Great Beauty of the osteoclast.

Arch Biochem Biophys 2014 Sep 27;558:70-8. Epub 2014 Jun 27.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2014.06.017DOI Listing
September 2014

The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss.

J Bone Miner Res 2014 Aug;29(8):1833-46

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jbmr.2206DOI Listing
August 2014

Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology.

Lab Invest 2014 Mar 16;94(3):275-85. Epub 2013 Dec 16.

1] Institut National de la Santé et de la Recherche Médicale U606, Hôpital Lariboisière, Paris, France [2] INSERM U606, Os et articulations, Bâtiment Viggo Petersen, Secteur Viole, Fédération de Rhumatologie, Hôpital Lariboisière, Paris, France.

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http://dx.doi.org/10.1038/labinvest.2013.140DOI Listing
March 2014

Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression.

BMC Cancer 2014 Mar 5;14:154. Epub 2014 Mar 5.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1186/1471-2407-14-154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945608PMC
March 2014

Generation of the first autosomal dominant osteopetrosis type II (ADO2) disease models.

Bone 2014 Feb 1;59:66-75. Epub 2013 Nov 1.

Regenerative Medicine Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Piazza Sant'Onofrio 4, 00165 Rome, Italy.

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http://dx.doi.org/10.1016/j.bone.2013.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889206PMC
February 2014

Mechanisms of osteoclast-dependent bone formation.

Authors:
Anna Teti

Bonekey Rep 2013 Dec 4;2:449. Epub 2013 Dec 4.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila , L'Aquila, Italy.

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http://dx.doi.org/10.1038/bonekey.2013.183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872977PMC
December 2013

Proline/arginine-rich end leucine-rich repeat protein N-terminus is a novel osteoclast antagonist that counteracts bone loss.

J Bone Miner Res 2013 Sep;28(9):1912-24

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jbmr.1951DOI Listing
September 2013

Osteoclasts and hematopoiesis.

Authors:
Anna Teti

Bonekey Rep 2012 28;1:46. Epub 2012 Mar 28.

Department of Experimental Medicine, University of L'Aquila , L'Aquila, Italy .

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http://dx.doi.org/10.1038/bonekey.2012.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727773PMC
August 2013

The tight relationship between osteoclasts and the immune system.

Inflamm Allergy Drug Targets 2012 Jun;11(3):181-7

Regenerative Medicine Unit, Ospedale Pediatrico Bambino Gesù, Rome, Italy.

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http://dx.doi.org/10.2174/187152812800392733DOI Listing
June 2012

Bone cells and the mechanisms of bone remodelling.

Front Biosci (Elite Ed) 2012 Jan 1;4:2302-21. Epub 2012 Jan 1.

Unita di Medicina Rigenerativa, Ospedale Pediatrico Bambino Gesu, piazza Sant Onofrio 4, 00165 Rome.

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http://dx.doi.org/10.2741/543DOI Listing
January 2012

c-Src and IL-6 inhibit osteoblast differentiation and integrate IGFBP5 signalling.

Nat Commun 2012 Jan 17;3:630. Epub 2012 Jan 17.

Department of Experimental Medicine, University of L'Aquila, Via Vetoio - Coppito 2, L'Aquila 67100, Italy.

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http://dx.doi.org/10.1038/ncomms1651DOI Listing
January 2012

Bone development: overview of bone cells and signaling.

Authors:
Anna Teti

Curr Osteoporos Rep 2011 Dec;9(4):264-73

Department of Experimental Medicine, University of L'Aquila, Via Vetoio-Coppito 2, 67100, L'Aquila, Italy.

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http://link.springer.com/10.1007/s11914-011-0078-8
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http://dx.doi.org/10.1007/s11914-011-0078-8DOI Listing
December 2011

The central role of the skeleton in chronic diseases.

Arch Biochem Biophys 2010 Nov;503(1)

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http://dx.doi.org/10.1016/j.abb.2010.09.007DOI Listing
November 2010

Design of novel three-phase PCL/TZ-HA biomaterials for use in bone regeneration applications.

J Mater Sci Mater Med 2010 Sep 2;21(9):2569-81. Epub 2010 Jul 2.

Interdisciplinary Research Centre on Biomaterials (CRIB) and Italian Institute of Technology, Piazzale Tecchio 80, 80125, Naples, Italy.

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http://dx.doi.org/10.1007/s10856-010-4119-0DOI Listing
September 2010

Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.

Cell 2010 Jul;142(2):296-308

Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.cell.2010.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910411PMC
July 2010

Osteomimicry: how tumor cells try to deceive the bone.

Front Biosci (Schol Ed) 2010 Jun 1;2:907-15. Epub 2010 Jun 1.

Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.2741/s110DOI Listing
June 2010

Expanding the role of Src and protein-tyrosine phosphatases balance in modulating osteoblast metabolism: lessons from mice.

Biochimie 2010 Apr 18;92(4):327-32. Epub 2010 Jan 18.

Department of Biochemistry, University of Campinas, Campinas, SP, Brazil.

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http://dx.doi.org/10.1016/j.biochi.2010.01.002DOI Listing
April 2010

Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice.

J Bone Miner Res 2009 May;24(5):775-84

Service of Bone Diseases, Department of Rehabilitation and Geriatrics, WHO Center for Osteoporosis Prevention, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland.

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http://dx.doi.org/10.1359/jbmr.081237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672203PMC
May 2009

Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited.

Bone 2009 Jan 14;44(1):11-6. Epub 2008 Oct 14.

Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1016/j.bone.2008.09.017DOI Listing
January 2009

A six-gene signature predicting breast cancer lung metastasis.

Cancer Res 2008 Aug;68(15):6092-9

Centre René Huguenin, Fédération Nationale des Centres de Lutte Contre le Cancer and Institut National de la Sante et de la Recherche Medicale, U735, Saint-Cloud, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0436DOI Listing
August 2008

Osteoclast receptors and signaling.

Arch Biochem Biophys 2008 May 24;473(2):147-60. Epub 2008 Jan 24.

Department of Experimental Medicine, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1016/j.abb.2008.01.011DOI Listing
May 2008

Bone metastasis: pathogenesis and therapeutic implications.

Clin Exp Metastasis 2007 16;24(8):599-608. Epub 2007 Nov 16.

INSERM, Research Unit 664, Laennec School of Medicine, Lyon, France.

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http://dx.doi.org/10.1007/s10585-007-9112-8DOI Listing
April 2008

Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases.

Anticancer Agents Med Chem 2008 Apr;8(3):342-9

Department of Experimental Medicine, University of L'Aquila, Via Vetoio - Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.2174/187152008783961905DOI Listing
April 2008

Genetics, pathogenesis and complications of osteopetrosis.

Bone 2008 Jan 30;42(1):19-29. Epub 2007 Aug 30.

Department of Experimental Medicine, Via Vetoio - Coppito 2, 67100 L'Aquila, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S87563282070062
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http://dx.doi.org/10.1016/j.bone.2007.08.029DOI Listing
January 2008

Modeled microgravity stimulates osteoclastogenesis and bone resorption by increasing osteoblast RANKL/OPG ratio.

J Cell Biochem 2007 Feb;100(2):464-73

Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/jcb.21059DOI Listing
February 2007

Modulation of human estrogen receptor alpha F promoter by a protein kinase C/c-Src-dependent mechanism in osteoblast-like cells.

J Mol Endocrinol 2006 Dec;37(3):489-502

Department of Experimental Medicine, University of L'Aquila, via Vetoio Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1677/jme.1.02055DOI Listing
December 2006

Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy.

J Pharmacol Exp Ther 2006 Jul 20;318(1):161-72. Epub 2006 Apr 20.

Department of Experimental Medicine, Via Vetoio-Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1124/jpet.106.102004DOI Listing
July 2006

Osteoblast-conditioned media stimulate membrane vesicle shedding in prostate cancer cells.

Int J Oncol 2006 Apr;28(4):909-14

Department of Experimental Medicine, University of L'Aquila, 67100 L'Aquila, Italy.

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April 2006

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice.

Endocr Relat Cancer 2006 Mar;13(1):197-210

Department of Surgery, University of L'Aquila via Vetoio, Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1677/erc.1.01100DOI Listing
March 2006

Polymorphisms of the CLCN7 gene are associated with BMD in women.

J Bone Miner Res 2005 Nov 18;20(11):1960-7. Epub 2005 Jul 18.

Bone Research Group, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1359/JBMR.050717DOI Listing
November 2005

A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells.

J Cell Sci 2005 Aug 12;118(Pt 15):3263-75. Epub 2005 Jul 12.

Department of Experimental Medicine, University of L'Aquila, via Vetoio - Coppito 2, 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1242/jcs.02436DOI Listing
August 2005

Evaluation of metastatic potential in prostate carcinoma: an in vivo model.

Int J Oncol 2004 Dec;25(6):1713-20

Department of Basic and Applied Biology, University of L'Aquila, Medical School and Science and Technology School, Coppito-2, I-67100 L'Aquila, Italy.

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December 2004

Imbalance of osteoclastogenesis-regulating factors in patients with celiac disease.

J Bone Miner Res 2004 Jul 22;19(7):1112-21. Epub 2004 Mar 22.

Istituto Dermopatico dell'Immacolata, Istituto di Ricovero e Cura a Carattere Scientifico, Roma, Italy.

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http://dx.doi.org/10.1359/JBMR.040319DOI Listing
July 2004

Increase in cytosolic Ca2+ induced by elevation of extracellular Ca2+ in skeletal myogenic cells.

Am J Physiol Cell Physiol 2003 Apr 18;284(4):C969-76. Epub 2002 Dec 18.

Dipartimento di Istologia ed Embriologia Medica, Università La Sapienza, 00161 Rome, Italy.

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http://dx.doi.org/10.1152/ajpcell.00237.2002DOI Listing
April 2003

Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV).

J Cell Biochem 2002 ;85(1):167-79

Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy.

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June 2002