Anna Partyka

Anna Partyka

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Anna Partyka

Anna Partyka

Publications by authors named "Anna Partyka"

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Multifunctional 6-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1,2-benzoxazoles targeting behavioral and psychological symptoms of dementia (BPSD).

Eur J Med Chem 2020 Apr 18;191:112149. Epub 2020 Feb 18.

Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland; Adamed Pharma S.A., Pienkow, 6A Mariana Adamkiewicza Street, 05-152, Czosnów, Poland.

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http://dx.doi.org/10.1016/j.ejmech.2020.112149DOI Listing
April 2020

The preclinical discovery and development of paliperidone for the treatment of schizophrenia.

Expert Opin Drug Discov 2020 Mar 29;15(3):279-292. Epub 2019 Oct 29.

Jagiellonian University Medical College, Department of Clinical Pharmacy, Kraków, Poland.

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http://dx.doi.org/10.1080/17460441.2020.1682994DOI Listing
March 2020

Discovery and Development of Non-Dopaminergic Agents for the Treatment of Schizophrenia: Overview of the Preclinical and Early Clinical Studies.

Curr Med Chem 2019 ;26(25):4885-4913

Department of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.

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http://dx.doi.org/10.2174/0929867326666190710172002DOI Listing
November 2019

5-HT receptor agonist and antagonist improve memory impairments and hippocampal BDNF signaling alterations induced by MK-801.

Brain Res 2019 11 11;1722:146375. Epub 2019 Aug 11.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.

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http://dx.doi.org/10.1016/j.brainres.2019.146375DOI Listing
November 2019

Phosphodiesterase 10 Inhibitors - Novel Perspectives for Psychiatric and Neurodegenerative Drug Discovery.

Curr Med Chem 2018 ;25(29):3455-3481

Department of Medicinal Chemistry, Jagiellonian University Medical College, Krakow, Poland.

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http://dx.doi.org/10.2174/0929867325666180309110629DOI Listing
October 2018

The Influence of Genetic Variations in the Gene on the Outcome after Allogeneic Hematopoietic Stem Cell Transplantation.

J Immunol Res 2018 7;2018:3826989. Epub 2018 Feb 7.

Department of Experimental Therapy, L. Hirszfeld Institute of Immunology & Experimental Therapy, Polish Academy of Sciences, R Weigl 12, 53-114 Wroclaw, Poland.

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http://dx.doi.org/10.1155/2018/3826989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821961PMC
August 2018

The preclinical discovery and development of cariprazine for the treatment of schizophrenia.

Expert Opin Drug Discov 2018 08 3;13(8):779-790. Epub 2018 May 3.

b Department of Pharmaceutical Chemistry , Jagiellonian University Medical College , Kraków , Poland.

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http://dx.doi.org/10.1080/17460441.2018.1471057DOI Listing
August 2018

Activity of Serotonin 5-HT Receptor Biased Agonists in Rat: Anxiolytic and Antidepressant-like properties.

ACS Chem Neurosci 2018 05 11;9(5):1040-1050. Epub 2018 Jan 11.

Neurolixis Inc., 34145 Pacific Coast Highway #504 , Dana Point , California 92629 , United States.

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http://pubs.acs.org/doi/10.1021/acschemneuro.7b00443
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http://dx.doi.org/10.1021/acschemneuro.7b00443DOI Listing
May 2018

MF-8, a novel promising arylpiperazine-hydantoin based 5-HT receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation.

Bioorg Med Chem Lett 2018 03 3;28(5):878-883. Epub 2018 Feb 3.

Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.02.003DOI Listing
March 2018

Study on the effect of EMD386088, a 5-HT receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats.

Naunyn Schmiedebergs Arch Pharmacol 2018 Jan 27;391(1):37-49. Epub 2017 Oct 27.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Cracow, Poland.

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http://dx.doi.org/10.1007/s00210-017-1431-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748433PMC
January 2018

The mRNA expression levels of uncoupling proteins 1 and 2 in mononuclear cells from patients with metabolic disorders: obesity and type 2 diabetes mellitus.

Postepy Hig Med Dosw (Online) 2017 Oct;71(0):895-900

aboratory of Immunopathology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.

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http://phmd.pl/gicid/01.3001.0010.5386
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http://dx.doi.org/10.5604/01.3001.0010.5386DOI Listing
October 2017

CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves' disease and modulates clinical phenotype of disease.

Endocrine 2017 Jan 16;55(1):186-199. Epub 2016 Sep 16.

Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, L. Pasteur 4, Wroclaw, 50-367, Poland.

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http://dx.doi.org/10.1007/s12020-016-1096-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225215PMC
January 2017

Association of 3' nearby gene BTLA polymorphisms with the risk of renal cell carcinoma in the Polish population.

Urol Oncol 2016 09 24;34(9):419.e13-9. Epub 2016 May 24.

Department of Experimental Therapy, L. Hirszfeld Institute of Immunology & Experimental Therapy, Wroclaw, Poland; Department of Urology and Oncological Urology, Wroclaw Medical University, Wroclaw, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2016.04.010DOI Listing
September 2016

Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats.

Naunyn Schmiedebergs Arch Pharmacol 2016 Aug 23;389(8):839-49. Epub 2016 Apr 23.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Cracow, Poland.

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http://dx.doi.org/10.1007/s00210-016-1245-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939156PMC
August 2016

Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease.

ACS Chem Neurosci 2016 07 5;7(7):972-83. Epub 2016 May 5.

Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Université de Montpellier Campus Triolet Place Eugène Bataillon, 34095 CEDEX 5 Montpellier, France.

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http://dx.doi.org/10.1021/acschemneuro.6b00090DOI Listing
July 2016

ADN-1184, a monoaminergic ligand with 5-HT6/7 receptor antagonist action, exhibits activity in animal models of anxiety.

Naunyn Schmiedebergs Arch Pharmacol 2016 Jun 16;389(6):593-602. Epub 2016 Mar 16.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Cracow, Poland.

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http://dx.doi.org/10.1007/s00210-016-1229-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867004PMC
June 2016

N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties.

ACS Med Chem Lett 2016 Jun 7;7(6):618-22. Epub 2016 Apr 7.

Faculty of Health Sciences, Jagiellonian University Medical College, Michalowskiego 20, 31-126 Krakow, Poland; Department of Medicinal Chemistry, Department of Pharmacokinetics and Drug Metabolism, and Department of Behavioral Neuroscience and Drug Development, Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Krakow, Poland.

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http://dx.doi.org/10.1021/acsmedchemlett.6b00056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904269PMC
June 2016

Towards new 5-HT7 antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties.

Eur J Med Chem 2016 Jan 30;108:334-346. Epub 2015 Nov 30.

Department of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.11.040DOI Listing
January 2016

N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT(7) receptor selectivity versus multireceptor profile.

Bioorg Med Chem 2016 Jan 30;24(2):130-9. Epub 2015 Nov 30.

Department of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.11.041DOI Listing
January 2016

Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats.

Naunyn Schmiedebergs Arch Pharmacol 2015 Oct 16;388(10):1079-88. Epub 2015 Jun 16.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688, Cracow, Poland,

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http://link.springer.com/content/pdf/10.1007%2Fs00210-015-11
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http://link.springer.com/10.1007/s00210-015-1141-2
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http://dx.doi.org/10.1007/s00210-015-1141-2DOI Listing
October 2015

Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.

Bioorg Med Chem 2015 Jul 16;23(13):3436-47. Epub 2015 Apr 16.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896150032
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http://dx.doi.org/10.1016/j.bmc.2015.04.026DOI Listing
July 2015

A CT60G>A polymorphism in the CTLA-4 gene of the recipient may confer susceptibility to acute graft versus host disease after allogeneic hematopoietic stem cell transplantation.

Immunogenetics 2015 Jun 5;67(5-6):295-304. Epub 2015 May 5.

Department of Experimental Therapy, L. Hirszfeld Institute of Immunology & Experimental Therapy, Polish Academy of Science, R. Weigl 12, 53-114, Wroclaw, Poland,

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http://dx.doi.org/10.1007/s00251-015-0840-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427628PMC
June 2015

Pretransplant donor and recipient CTLA-4 mRNA and protein levels as a prognostic marker for aGvHD in allogeneic hematopoietic stem cell transplantation.

Immunol Lett 2015 May 1;165(1):52-9. Epub 2015 Apr 1.

Department of Experimental Therapy, L. Hirszfeld Institute of Immunology & Experimental Therapy, R Weigl St 12, Wroclaw 53-114, Poland.

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http://dx.doi.org/10.1016/j.imlet.2015.03.011DOI Listing
May 2015

Towards novel 5-HT7versus 5-HT1A receptor ligands among LCAPs with cyclic amino acid amide fragments: design, synthesis, and antidepressant properties. Part II.

Eur J Med Chem 2015 Mar 24;92:202-11. Epub 2014 Dec 24.

Department of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.12.041DOI Listing
March 2015

Gene polymorphisms of novel immunotolerant molecule BTLA: distribution of alleles, genotypes and haplotypes in Polish Caucasian population.

Arch Immunol Ther Exp (Warsz) 2015 Feb 3;63(1):73-8. Epub 2014 Sep 3.

Department of Experimental Therapy, Institute of Immunology and Experimental Therapy, Polish Academy of Science, Weigla 12, 53-114, Wroclaw, Poland.

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http://dx.doi.org/10.1007/s00005-014-0300-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289528PMC
February 2015

Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.

Bioorg Med Chem 2015 Jan 11;23(1):212-21. Epub 2014 Nov 11.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2014.11.008DOI Listing
January 2015

Novel tricyclic[2,1-f]theophylline derivatives of LCAP with activity in mouse models of affective disorders.

J Pharm Pharmacol 2014 Dec 13;66(12):1755-62. Epub 2014 Aug 13.

Department of Clinical Pharmacy, Jagiellonian University Medical College, Kraków, Poland.

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http://dx.doi.org/10.1111/jphp.12305DOI Listing
December 2014

Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.

Neuropharmacology 2014 Oct 4;85:253-62. Epub 2014 Jun 4.

Department of Clinical Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.

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http://dx.doi.org/10.1016/j.neuropharm.2014.05.036DOI Listing
October 2014

Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement.

Rheumatol Int 2014 Feb 13;34(2):243-53. Epub 2013 Nov 13.

Department of Immunopathology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114, Wrocław, Poland,

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http://dx.doi.org/10.1007/s00296-013-2895-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904036PMC
February 2014

Quinoline- and isoquinoline-sulfonamide analogs of aripiprazole: novel antipsychotic agents?

Future Med Chem 2014 Jan;6(1):57-75

Department of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland.

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http://dx.doi.org/10.4155/fmc.13.158DOI Listing
January 2014

Synthesis and pharmacological evaluation of novel tricyclic[2,1-f]theophylline derivatives.

Arch Pharm (Weinheim) 2013 Nov 1;346(11):832-9. Epub 2013 Oct 1.

Department of Pharmaceutical Chemistry, Jagiellonian University Medical College, Kraków, Poland.

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http://dx.doi.org/10.1002/ardp.201300257DOI Listing
November 2013

Anxiolytic-like activity of zinc in rodent tests.

Pharmacol Rep 2011 ;63(4):1050-5

Department of Clinical Pharmacy, Jagiellonian University, Collegium Medicum, Medyczna 9, PL 30-688 Kraków, Poland.

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http://dx.doi.org/10.1016/s1734-1140(11)70621-1DOI Listing
February 2012

Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior.

Pharmacol Rep 2007 Nov-Dec;59(6):757-62

Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343 Kraków, Poland.

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September 2008

Medium supplementation with zinc enables detection of imipramine-induced adaptation in glycine/NMDA receptors labeled with [3H]L-689,560.

Pharmacol Rep 2006 Sep-Oct;58(5):753-7

Laboratory of Pharmacobiology, Department of Cytobiology and Histochemistry, Collegium Medicum, Jagiellonian University, Medyczna 9, PL 30-688 Kraków, Poland.

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March 2007