Anna Mandinova

Anna Mandinova

UNVERIFIED PROFILE

Are you Anna Mandinova?   Register this Author

Register author
Anna Mandinova

Anna Mandinova

Publications by authors named "Anna Mandinova"

Are you Anna Mandinova?   Register this Author

41Publications

878Reads

40Profile Views

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Nat Commun 2018 04 30;9(1):1734. Epub 2018 Apr 30.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-04092-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928080PMC
April 2018

GDC-0879, a BRAF Inhibitor, Protects Kidney Podocytes from Death.

Cell Chem Biol 2018 02 14;25(2):175-184.e4. Epub 2017 Dec 14.

Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chembiol.2017.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819995PMC
February 2018

Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.

PLoS One 2016 13;11(9):e0162686. Epub 2016 Sep 13.

Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162686PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021346PMC
July 2017

Emerging roles of p53 and other tumour-suppressor genes in immune regulation.

Nat Rev Immunol 2016 12 26;16(12):741-750. Epub 2016 Sep 26.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri.2016.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325695PMC
December 2016

Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling.

Cell Rep 2016 06 16;16(1):28-36. Epub 2016 Jun 16.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.05.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957947PMC
June 2016

Sustained Akt Activity Is Required to Maintain Cell Viability in Seborrheic Keratosis, a Benign Epithelial Tumor.

J Invest Dermatol 2016 Mar 29;136(3):696-705. Epub 2015 Dec 29.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Harvard Stem Cell Institute, Cambridge, Massachusetts, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022202X150031
Publisher Site
http://dx.doi.org/10.1016/j.jid.2015.12.023DOI Listing
March 2016

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.

Oncotarget 2015 Aug;6(24):19990-20001

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652982PMC
http://dx.doi.org/10.18632/oncotarget.4598DOI Listing
August 2015

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.

Science 2015 Jul;349(6247):1261669

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Charlestown, MA 02129, USA. Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1261669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215039PMC
July 2015

Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.

Cancer Res 2014 Apr 13;74(7):2082-93. Epub 2014 Feb 13.

Authors' Affiliations: Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown; Broad Institute of Harvard and MIT, Cambridge Center, Massachusetts; Institute of Immunology, Sofia, Bulgaria; and Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-0452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031027PMC
April 2014

High-throughput, high-content screening for novel pigmentation regulators using a keratinocyte/melanocyte co-culture system.

Exp Dermatol 2014 Feb;23(2):125-9

Department of Dermatology, Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Dermatology, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/exd.12322
Publisher Site
http://dx.doi.org/10.1111/exd.12322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977999PMC
February 2014

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.

Nat Commun 2013 ;4:2189

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms3189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740589PMC
January 2014

Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.

ACS Chem Biol 2013 Oct 13;8(10):2145-50. Epub 2013 Aug 13.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School , Charlestown, Massachusetts 02129, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cb400430tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800496PMC
October 2013

CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress.

Cell Rep 2013 Oct 17;5(2):331-9. Epub 2013 Oct 17.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2013.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833439PMC
October 2013

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Nature 2011 Jul 13;475(7355):231-4. Epub 2011 Jul 13.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature10167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316487PMC
July 2011

DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.

J Biol Chem 2011 05 13;286(20):17672-81. Epub 2011 Mar 13.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.236612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093843PMC
May 2011

The p53 pathway as a target in cancer therapeutics: obstacles and promise.

Sci Transl Med 2011 Jan;3(64):64rv1

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.3001366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763710PMC
January 2011

Maximizing early detection of esophageal squamous cell carcinoma via SILAC-proteomics.

Cancer Biol Ther 2010 Oct 15;10(8):811-3. Epub 2010 Oct 15.

Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093917PMC
http://dx.doi.org/10.4161/cbt.10.8.13754DOI Listing
October 2010

A small molecule that binds Hedgehog and blocks its signaling in human cells.

Nat Chem Biol 2009 Mar 18;5(3):154-6. Epub 2009 Jan 18.

Broad Institute of Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nchembio.142
Publisher Site
http://dx.doi.org/10.1038/nchembio.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770933PMC
March 2009

Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway.

Exp Cell Res 2007 Sep 6;313(15):3308-18. Epub 2007 Jul 6.

Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2007.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001265PMC
September 2007

CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner.

EMBO J 2007 Jul 28;26(14):3410-22. Epub 2007 Jun 28.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.emboj.7601779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933410PMC
July 2007

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.

Genes Dev 2006 Apr;20(8):1028-42

Cutaneous Biology Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA, and Department of Biochemistry, University of Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472299PMC
http://dx.doi.org/10.1101/gad.1406006DOI Listing
April 2006

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.

Proc Natl Acad Sci U S A 2006 Mar 24;103(10):3799-804. Epub 2006 Feb 24.

Swiss Institute for Experimental Cancer Research, National Center of Competence in Research in Molecular Oncology, 155 Chemin des Boveresses, CH-1066 Epalinges/Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0600065103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450156PMC
March 2006

The non-classical export routes: FGF1 and IL-1alpha point the way.

J Cell Sci 2003 Dec;116(Pt 24):4871-81

Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, Maine 04074, USA.

View Article

Download full-text PDF

Source
http://jcs.biologists.org/cgi/doi/10.1242/jcs.00872
Publisher Site
http://dx.doi.org/10.1242/jcs.00872DOI Listing
December 2003

S100A13 mediates the copper-dependent stress-induced release of IL-1alpha from both human U937 and murine NIH 3T3 cells.

J Cell Sci 2003 Jul 13;116(Pt 13):2687-96. Epub 2003 May 13.

Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME 04074, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.00471DOI Listing
July 2003

Notch activation suppresses fibroblast growth factor-dependent cellular transformation.

J Biol Chem 2003 May 21;278(18):16405-13. Epub 2003 Feb 21.

Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M300464200DOI Listing
May 2003