Publications by authors named "Anna Ludovica Fracanzani"

100Publications

MAFLD in COVID-19 patients: an insidious enemy.

Expert Rev Gastroenterol Hepatol 2020 Aug 4:1-6. Epub 2020 Aug 4.

General Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico , Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17474124.2020.1801417DOI Listing
August 2020

Neurotensin up-regulation is associated with advanced fibrosis and hepatocellular carcinoma in patients with MAFLD.

Biochim Biophys Acta Mol Cell Biol Lipids 2020 Oct 11;1865(10):158765. Epub 2020 Jul 11.

General Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy; Departments of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2020.158765DOI Listing
October 2020

Genomewide Association Study of Severe Covid-19 with Respiratory Failure.

Authors:
David Ellinghaus Frauke Degenhardt Luis Bujanda Maria Buti Agustín Albillos Pietro Invernizzi Javier Fernández Daniele Prati Guido Baselli Rosanna Asselta Marit M Grimsrud Chiara Milani Fátima Aziz Jan Kässens Sandra May Mareike Wendorff Lars Wienbrandt Florian Uellendahl-Werth Tenghao Zheng Xiaoli Yi Raúl de Pablo Adolfo G Chercoles Adriana Palom Alba-Estela Garcia-Fernandez Francisco Rodriguez-Frias Alberto Zanella Alessandra Bandera Alessandro Protti Alessio Aghemo Ana Lleo Andrea Biondi Andrea Caballero-Garralda Andrea Gori Anja Tanck Anna Carreras Nolla Anna Latiano Anna Ludovica Fracanzani Anna Peschuck Antonio Julià Antonio Pesenti Antonio Voza David Jiménez Beatriz Mateos Beatriz Nafria Jimenez Carmen Quereda Cinzia Paccapelo Christoph Gassner Claudio Angelini Cristina Cea Aurora Solier David Pestaña Eduardo Muñiz-Diaz Elena Sandoval Elvezia M Paraboschi Enrique Navas Félix García Sánchez Ferruccio Ceriotti Filippo Martinelli-Boneschi Flora Peyvandi Francesco Blasi Luis Téllez Albert Blanco-Grau Georg Hemmrich-Stanisak Giacomo Grasselli Giorgio Costantino Giulia Cardamone Giuseppe Foti Serena Aneli Hayato Kurihara Hesham ElAbd Ilaria My Iván Galván-Femenia Javier Martín Jeanette Erdmann Jose Ferrusquía-Acosta Koldo Garcia-Etxebarria Laura Izquierdo-Sanchez Laura R Bettini Lauro Sumoy Leonardo Terranova Leticia Moreira Luigi Santoro Luigia Scudeller Francisco Mesonero Luisa Roade Malte C Rühlemann Marco Schaefer Maria Carrabba Mar Riveiro-Barciela Maria E Figuera Basso Maria G Valsecchi María Hernandez-Tejero Marialbert Acosta-Herrera Mariella D'Angiò Marina Baldini Marina Cazzaniga Martin Schulzky Maurizio Cecconi Michael Wittig Michele Ciccarelli Miguel Rodríguez-Gandía Monica Bocciolone Monica Miozzo Nicola Montano Nicole Braun Nicoletta Sacchi Nilda Martínez Onur Özer Orazio Palmieri Paola Faverio Paoletta Preatoni Paolo Bonfanti Paolo Omodei Paolo Tentorio Pedro Castro Pedro M Rodrigues Aaron Blandino Ortiz Rafael de Cid Ricard Ferrer Roberta Gualtierotti Rosa Nieto Siegfried Goerg Salvatore Badalamenti Sara Marsal Giuseppe Matullo Serena Pelusi Simonas Juzenas Stefano Aliberti Valter Monzani Victor Moreno Tanja Wesse Tobias L Lenz Tomas Pumarola Valeria Rimoldi Silvano Bosari Wolfgang Albrecht Wolfgang Peter Manuel Romero-Gómez Mauro D'Amato Stefano Duga Jesus M Banales Johannes R Hov Trine Folseraas Luca Valenti Andre Franke Tom H Karlsen

N Engl J Med 2020 Jun 17. Epub 2020 Jun 17.

From the Institute of Clinical Molecular Biology, Christian-Albrechts-University (D.E., F.D., J.K., S. May, M. Wendorff, L.W., F.U.-W., X.Y., A.T., A. Peschuck, C.G., G.H.-S., H.E.A., M.C.R., M.E.F.B., M. Schulzky, M. Wittig, N.B., S.J., T.W., W.A., M. D'Amato, A.F.), and University Hospital Schleswig-Holstein, Campus Kiel (N.B., A.F.), Kiel, the Institute for Cardiogenetics, University of Lübeck, Lübeck (J.E.), the German Research Center for Cardiovascular Research, partner site Hamburg-Lübeck-Kiel (J.E.), the University Heart Center Lübeck (J.E.), and the Institute of Transfusion Medicine, University Hospital Schleswig-Holstein (S.G.), Lübeck, Stefan-Morsch-Stiftung, Birkenfeld (M. Schaefer, W.P.), and the Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön (O.O., T.L.L.) - all in Germany; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (D.E.); the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital-University of the Basque Country (L.B., K.G.-E., L.I.-S., P.M.R., J.M.B.), Osakidetza Basque Health Service, Donostialdea Integrated Health Organization, Clinical Biochemistry Department (A.G.C., B.N.J.), and the Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute (M. D'Amato), San Sebastian, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Instituto de Salud Carlos III (L.B., M. Buti, A. Albillos, A. Palom, F.R.-F., B.M., L. Téllez, K.G.-E., L.I.-S., F.M., L.R., M.R.-B., M. Rodríguez-Gandía, P.M.R., M. Romero-Gómez, J.M.B.), the Departments of Gastroenterology (A. Albillos, B.M., L. Téllez, F.M., M. Rodríguez-Gandía), Intensive Care (R.P., A.B.O.), Respiratory Diseases (D.J., A.S., R.N.), Infectious Diseases (C.Q., E.N.), and Anesthesiology (D. Pestaña, N. Martínez), Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, University of Alcalá, and Histocompatibilidad y Biologia Molecular, Centro de Transfusion de Madrid (F.G.S.), Madrid, the Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus (M. Buti, A. Palom, L.R., M.R.-B.), Hospital Clinic, University of Barcelona, and the August Pi i Sunyer Biomedical Research Institute (J.F., F.A., E.S., J.F.-A., L.M., M.H.-T., P.C.), the European Foundation for the Study of Chronic Liver Failure (J.F.), Vall d'Hebron Institut de Recerca (A. Palom, F.R.-F., A.J., S. Marsal), and the Departments of Biochemistry (A.-E.G.-F., F.R.-F., A.C.-G., C.C., A.B.-G.), Intensive Care (R.F.), and Microbiology (T.P.), University Hospital Vall d'Hebron, the Immunohematology Department, Banc de Sang i Teixits, Autonomous University of Barcelona (E.M.-D.), Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Consortium for Biomedical Research in Epidemiology and Public Health and University of Barcelona, l'Hospitalet (V. Moreno), and Autonoma University of Barcelona (T.P.), Barcelona, Universitat Autònoma de Barcelona, Bellatera (M. Buti, F.R.-F., M.R.-B.), GenomesForLife-GCAT Lab Group, Germans Trias i Pujol Research Institute (A.C.N., I.G.-F., R.C.), and High Content Genomics and Bioinformatics Unit, Germans Trias i Pujol Research Institute (L. Sumoy), Badalona, Institute of Parasitology and Biomedicine Lopez-Neyra, Granada (J.M., M.A.-H.), the Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville (M. Romero-Gómez), and Ikerbasque, Basque Foundation for Science, Bilbao (M. D'Amato, J.M.B.) - all in Spain; the Division of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milan Bicocca (P.I., C.M.), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (D. Prati, G.B., A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, C.P., F.C., F.M.-B., F.P., F.B., G.G., G. Costantino, L. Terranova, L. Santoro, L. Scudeller, M. Carrabba, M. Baldini, M.M., N. Montano, R.G., S.P., S. Aliberti, V. Monzani, S. Bosari, L.V.), the Department of Biomedical Sciences, Humanitas University (R.A., A. Protti, A. Aghemo, A. Lleo, E.M.P., G. Cardamone, M. Cecconi, V.R., S.D.), Humanitas Clinical and Research Center, IRCCS (R.A., A. Protti, A. Aghemo, A. Lleo, A.V., C.A., E.M.P., H.K., I.M., M. Cecconi, M. Ciccarelli, M. Bocciolone, P.P., P.O., P.T., S. Badalamenti, S.D.), University of Milan (A.Z., A. Bandera, A.G., A.L.F., A. Pesenti, F.M.-B., F.P., F.B., G.G., G. Costantino, M.M., N. Montano, R.G., S.P., S. Aliberti, S. Bosari, L.V.), and the Center of Bioinformatics, Biostatistics, and Bioimaging (M.G.V.) and the Phase 1 Research Center (M. Cazzaniga), School of Medicine and Surgery, and the Departments of Emergency, Anesthesia, and Intensive Care (G.F.), Pneumologia (P.F.), and Infectious Diseases (P.B.); University of Milano-Bicocca, Milan, the European Reference Network on Hepatological Diseases (P.I., C.M.) and the Infectious Diseases Unit (P.B.), San Gerardo Hospital, Monza, the Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale, San Gerardo (A. Biondi, L.R.B., M. D'Angiò), the Gastroenterology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (A. Latiano, O.P.), the Department of Medical Sciences, Università degli Studi di Torino, Turin (S. Aneli, G.M.), and the Italian Bone Marrow Donor Registry, E.O. Ospedali Galliera, Genoa (N.S.) - all in Italy; the Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, and the Research Institute for Internal Medicine, Division of Surgery, Inflammatory Diseases, and Transplantation, Oslo University Hospital Rikshospitalet and University of Oslo (M.M.G., J.R.H., T.F., T.H.K.), and the Section for Gastroenterology, Department of Transplantation Medicine, Division for Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital Rikshospitalet (J.R.H., T.F., T.H.K.), Oslo; the School of Biological Sciences, Monash University, Clayton, VIC, Australia (T.Z., M. D'Amato); Private University in the Principality of Liechtenstein (C.G.); the Institute of Biotechnology, Vilnius University, Vilnius, Lithuania (S.J.); and the Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm (M. D'Amato).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa2020283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315890PMC
June 2020

Reply to Comment: Is there any place for SGLT2-inhibitors in post-liver transplantation patients?

Dig Liver Dis 2020 04 13;52(4):470-471. Epub 2020 Feb 13.

Unit of Medicine and Metabolic Disease, Department of Pathophysiology and Transplantation Fondazione Ca' Granda IRCCS, Ospedale Maggiore Policlinico University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2020.01.007DOI Listing
April 2020

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes.

EBioMedicine 2020 Feb 12;52:102658. Epub 2020 Feb 12.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Ospedale Policlinico via F Sforza 35, 20122 Milano, Italy; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2020.102658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026742PMC
February 2020

Liver involvement in Gaucher disease: A practical review for the hepatologist and the gastroenterologist.

Dig Liver Dis 2020 04 11;52(4):368-373. Epub 2020 Feb 11.

Regional Referral Centre for Lysosomal Storage Diseases, Division of Internal Medicine and Metabolism, Civil Hospital, AOU of Modena, University of Modena and Reggio Emilia, Modena, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2020.01.004DOI Listing
April 2020

mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance.

Nutrients 2019 Oct 29;11(11). Epub 2019 Oct 29.

General Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano 20122, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu11112597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893471PMC
October 2019

β-Klotho gene variation is associated with liver damage in children with NAFLD.

J Hepatol 2020 Mar 23;72(3):411-419. Epub 2019 Oct 23.

Research Unit of Molecular Genetics of Complex Phenotypes, Bambino Gesù Children's Hospital - IRCCS, Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2019.10.011DOI Listing
March 2020

High prevalence of early atherosclerotic and cardiac damage in patients undergoing liver transplantation: Preliminary results.

Dig Liver Dis 2020 01 11;52(1):84-90. Epub 2019 Sep 11.

Department of Pathophysiology and Transplantation, Unit of Medicine and Metabolic Disorders, Fondazione Ca' Granda IRCCS, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2019.07.007DOI Listing
January 2020

Lipid accumulation impairs lysosomal acid lipase activity in hepatocytes: Evidence in NAFLD patients and cell cultures.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 12 7;1864(12):158523. Epub 2019 Sep 7.

Department of Pathophysiology and Transplantation, Unit of Metabolic and Internal Medicine, University of Milan, Ca' Granda IRCCS Foundation, Maggiore Policlinico Hospital, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2019.158523DOI Listing
December 2019

Procoagulant imbalance influences cardiovascular and liver damage in chronic hepatitis C independently of steatosis.

Liver Int 2019 12 30;39(12):2309-2316. Epub 2019 Aug 30.

Unit of Medicine and Metabolic Diseases, Pathophysiology and Transplantation Department, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/liv.14213DOI Listing
December 2019

Brain involvement in non-alcoholic fatty liver disease (NAFLD): A systematic review.

Dig Liver Dis 2019 09 6;51(9):1214-1222. Epub 2019 Jun 6.

Department of Pathophysiology and Transplantation Ca' Granda IRCCS Foundation, Policlinico Hospital, University of Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2019.05.015DOI Listing
September 2019

Prevalence and Risk Factors of Significant Fibrosis in Patients With Nonalcoholic Fatty Liver Without Steatohepatitis.

Clin Gastroenterol Hepatol 2019 10 29;17(11):2310-2319.e6. Epub 2019 Jan 29.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Transfusion Medicine and Hematology, Translational Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2019.01.027DOI Listing
October 2019

Evaluation of three "beyond Baveno VI" criteria to safely spare endoscopies in compensated advanced chronic liver disease.

Dig Liver Dis 2019 08 11;51(8):1135-1140. Epub 2019 Jan 11.

CRC "A. M. e A. Migliavacca" Center for Liver Disease, Division of Gastroenterology and Hepatology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2018.12.025DOI Listing
August 2019

miRNA Signature in NAFLD: A Turning Point for a Non-Invasive Diagnosis.

Int J Mol Sci 2018 Dec 10;19(12). Epub 2018 Dec 10.

General Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano 20122, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms19123966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320931PMC
December 2018

FibroScan Identifies Patients With Nonalcoholic Fatty Liver Disease and Cardiovascular Damage.

Clin Gastroenterol Hepatol 2020 Feb 8;18(2):517-519. Epub 2018 Dec 8.

Sezione di Gastroenterologia e Epatologia, Di.Bi.M.I.S., University of Palermo, Palermo, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2018.11.011DOI Listing
February 2020

A sweet fever.

Intern Emerg Med 2019 10 8;14(7):1125-1128. Epub 2018 Nov 8.

Unit of Internal Medicine, Department of Pathophysiology and Transplantation, Ca' Granda IRCCS Foundation, Policlinico Hospital, University of Milan, via F.Sforza 35, 20122, Milan, Italy.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11739-018-1975-y
Publisher Site
http://dx.doi.org/10.1007/s11739-018-1975-yDOI Listing
October 2019

Progressive splenomegaly and mild thrombocytosis in beta-thalassaemia trait and coexisting hereditary hemochromatosis: possible confounders for a subsequent hematological diagnosis.

Intern Emerg Med 2019 08 14;14(5):763-766. Epub 2018 Sep 14.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11739-018-1947-2DOI Listing
August 2019

Subclinical cerebrovascular disease in NAFLD without overt risk factors for atherosclerosis.

Atherosclerosis 2018 01 16;268:27-31. Epub 2017 Nov 16.

Department of Internal Medicine, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2017.11.012DOI Listing
January 2018

Harmful and Beneficial Effects of Anticoagulants in Patients With Cirrhosis and Portal Vein Thrombosis.

Clin Gastroenterol Hepatol 2018 07 21;16(7):1146-1152.e4. Epub 2017 Oct 21.

A. M. and A. Migliavacca-Center for Liver Disease, Division of Gastroenterology and Hepatology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2017.10.016DOI Listing
July 2018

Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity.

Clin Gastroenterol Hepatol 2017 Oct 26;15(10):1604-1611.e1. Epub 2017 May 26.

Department of Pathophysiology and Transplantation, Unit of Metabolic and Internal Medicine, University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2017.04.045DOI Listing
October 2017

Liver fat accumulation is associated with circulating PCSK9.

Ann Med 2016 08 25;48(5):384-91. Epub 2016 May 25.

d Internal Medicine and Metabolic Diseases , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico , Milano , Italy ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/07853890.2016.1188328DOI Listing
August 2016

Vascular Damage in Patients with Nonalcoholic Fatty Liver Disease: Possible Role of Iron and Ferritin.

Int J Mol Sci 2016 May 5;17(5). Epub 2016 May 5.

Department of Pathophysiology and Transplantation, Ca' Granda IRCCS Foundation, Policlinico Hospital, University of Milan, Centre of the Study of Metabolic and Liver Diseases, Via Francesco Sforza 35, 20122 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms17050675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881501PMC
May 2016

Progression of carotid vascular damage and cardiovascular events in non-alcoholic fatty liver disease patients compared to the general population during 10 years of follow-up.

Atherosclerosis 2016 Mar 12;246:208-13. Epub 2016 Jan 12.

Department of Pathophysiology and Transplantation, Ca' Granda Foundation IRCCS Maggiore Policlinico Hospital, University of Milan, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2016.01.016DOI Listing
March 2016

Increased circulating adiponectin in males with chronic HCV hepatitis.

Eur J Intern Med 2015 Oct 17;26(8):635-9. Epub 2015 Aug 17.

Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Department of Pathophysiology and Transplantation, Centro Malattie Metaboliche del Fegato, Università degli Studi di Milano, Milano, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejim.2015.08.001DOI Listing
October 2015

High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload.

PLoS One 2015 3;10(2):e0116855. Epub 2015 Feb 3.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milano, Italy; Department of Pathophysiology and Transplantation, Metabolic Liver Diseases Research Center, Università degli Studi di Milano, Milano, Italy.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116855PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315491PMC
January 2016

The UCP2 -866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis.

Liver Int 2015 May 20;35(5):1574-80. Epub 2014 Nov 20.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/liv.12707DOI Listing
May 2015

Nonalcoholic fatty liver disease and vascular disease: state-of-the-art.

World J Gastroenterol 2014 Oct;20(37):13306-24

Silvia Fargion, Marianna Porzio, Anna Ludovica Fracanzani, Department of Pathophysiology and Transplantation, Metabolic Liver Diseases Research Center, Ca' Granda IRCCS Foundation, Policlinico Hospital Pad Granelli, 20122 Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v20.i37.13306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188888PMC
October 2014

Role of iron in hepatocellular carcinoma.

Clin Liver Dis (Hoboken) 2014 May 27;3(5):108-110. Epub 2014 May 27.

Fondazione Cà Granda, IRCCS, Ospedale Maggiore Policlinico, Physiopatology and Liver Transplantation Department University of Milan Milan Italy.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cld.350
Publisher Site
http://dx.doi.org/10.1002/cld.350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448713PMC
May 2014

A randomized trial of iron depletion in patients with nonalcoholic fatty liver disease and hyperferritinemia.

World J Gastroenterol 2014 Mar;20(11):3002-10

Luca Valenti, Anna Ludovica Fracanzani, Paola Dongiovanni, Serena Rovida, Raffaela Rametta, Erika Fatta, Edoardo Alessandro Pulixi, Silvia Fargion, Department of Pathophysiology and Transplantation, Metabolic Liver Diseases Research Center, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Policlinico, via F Sforza 35, 20122, Milano, Italy.

View Article

Download full-text PDF

Source
http://www.wjgnet.com/1007-9327/full/v20/i11/3002.htm
Publisher Site
http://dx.doi.org/10.3748/wjg.v20.i11.3002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961977PMC
March 2014

PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma.

PLoS One 2013 14;8(10):e75982. Epub 2013 Oct 14.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy ; Internal Medicine, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda - Ospedale Maggiore Policlinico Milano, Milano, Italy.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075982PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796509PMC
June 2014

Stage of change and motivation to healthier lifestyle in non-alcoholic fatty liver disease.

J Hepatol 2013 Apr 29;58(4):771-7. Epub 2012 Nov 29.

Unit of Metabolic Diseases and Clinical Dietetics, Alma Mater Studiorum University, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2012.11.031DOI Listing
April 2013

Liver transplantation for hepatocellular carcinoma in a patient with a novel telomerase mutation and steatosis.

J Hepatol 2013 Feb 19;58(2):399-401. Epub 2012 Sep 19.

Section of Internal Medicine, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2012.09.011DOI Listing
February 2013

The I148M PNPLA3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls.

BMC Gastroenterol 2012 Aug 16;12:111. Epub 2012 Aug 16.

Department of Internal Medicine, Università degli Studi Milano, UO Medicina Interna 1B, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-230X-12-111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444917PMC
August 2012

Effect of the A736V TMPRSS6 polymorphism on the penetrance and clinical expression of hereditary hemochromatosis.

J Hepatol 2012 Dec 8;57(6):1319-25. Epub 2012 Aug 8.

Department of Internal Medicine, UO Medicina Interna 1B, Università degli Studi, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, Milano, Italy.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016882781200617
Publisher Site
http://dx.doi.org/10.1016/j.jhep.2012.07.041DOI Listing
December 2012

Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease.

PLoS One 2012 25;7(7):e41183. Epub 2012 Jul 25.

Department of Internal Medicine, Centro Studi Malattie Metaboliche del Fegato, University of Milano, Maggiore Policlinico Hospital, IRCCS Ca' Granda Foundation, Milano, Italy.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041183PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405067PMC
March 2013

Iron in fatty liver and in the metabolic syndrome: a promising therapeutic target.

J Hepatol 2011 Oct 28;55(4):920-32. Epub 2011 Jun 28.

Department of Internal Medicine, Centro Malattie Metaboliche del Fegato, Università degli Studi di Milano, and Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2011.05.008DOI Listing
October 2011

Patatin-like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C.

Hepatology 2011 Mar 11;53(3):791-9. Epub 2011 Feb 11.

Department of Internal Medicine, Università degli Studi, Fondazione IRCCS Ospedale Maggiore Policlinico "Ca' Granda" IRCCS, Milan, Italy.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hep.24123
Publisher Site
http://dx.doi.org/10.1002/hep.24123DOI Listing
March 2011

Serum hepcidin and macrophage iron correlate with MCP-1 release and vascular damage in patients with metabolic syndrome alterations.

Arterioscler Thromb Vasc Biol 2011 Mar 23;31(3):683-90. Epub 2010 Dec 23.

Centro Malattie Metaboliche del Fegato, Department of Internal Medicine, Università degli Studi, Ospedale Maggiore Policlinico Ca' Granda IRCCS, Milano, Via F Sforza 35, 20122 Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.110.214858DOI Listing
March 2011

Risk of nonalcoholic steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease and low visceral adiposity.

J Hepatol 2011 Jun 11;54(6):1244-9. Epub 2010 Nov 11.

Dipartimento di Medicina Interna, Centro Studi Malattie Metaboliche del Fegato, Università degli Studi di Milano, Ospedale Maggiore Policlinico, IRCCS, Fondazione Ca' Granda, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2010.09.037DOI Listing
June 2011

Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study.

BMC Gastroenterol 2010 Sep 8;10:102. Epub 2010 Sep 8.

Department of Internal Medicine, Metabolic Liver Diseases Research Center, Università degli Studi di Milano, Fondazione Ospedale Policlinico Ca' Granda IRCCS, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-230X-10-102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944335PMC
September 2010

Beyond hereditary hemochromatosis: new insights into the relationship between iron overload and chronic liver diseases.

Dig Liver Dis 2011 Feb 24;43(2):89-95. Epub 2010 Aug 24.

The Department of Internal Medicine, Università degli Studi, Fondazione IRCCS Ospedale Maggiore Policlinico Ca' Granda IRCCS, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2010.07.006DOI Listing
February 2011

Beta-globin mutations are associated with parenchymal siderosis and fibrosis in patients with non-alcoholic fatty liver disease.

J Hepatol 2010 Nov 25;53(5):927-33. Epub 2010 Jul 25.

Department of Internal Medicine, Università degli Studi Milano, UO Medicina Interna 1B, Fondazione Ospedale Policlinico MaRE IRCCS, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2010.05.023DOI Listing
November 2010

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

Hepatology 2010 Apr;51(4):1209-17

Department of Internal Medicine, Università degli Studi Milano, UO Medicina Interna 1B, Fondazione Ospedale Policlinico MaRE Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.23622DOI Listing
April 2010

Hemochromatosis in Italy in the last 30 years: role of genetic and acquired factors.

Hepatology 2010 Feb;51(2):501-10

Department of Internal Medicine, Policlinico Mangiagalli Regina Elena Hospital Foundation IRCCS, University of Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.23333DOI Listing
February 2010

Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis.

Am J Pathol 2010 Feb 17;176(2):1006-17. Epub 2009 Dec 17.

Center of Metabolic and Liver Diseases, Department of Internal Medicine, University of Milano, Ospedale Policlinico Mangiagalli e Regina Elena Fondazione IRCCS, 20122 Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808103PMC
February 2010

HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease.

Gastroenterology 2010 Mar 18;138(3):905-12. Epub 2009 Nov 18.

Department of Internal Medicine, Università degli Studi di Milano, Ospedale Maggiore Policlinico IRCCS, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2009.11.013DOI Listing
March 2010

The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease?

Semin Immunopathol 2009 Sep 14;31(3):359-69. Epub 2009 May 14.

Department of Internal Medicine, Università degli Studi di Milano, Padiglione Granelli, Ospedale Policlinico IRCCS, via F Sforza 35, 20122, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00281-009-0152-9DOI Listing
September 2009

Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: a role for insulin resistance and diabetes.

Hepatology 2008 Sep;48(3):792-8

Department of Internal Medicine, Scientific Institute of Recovery and Cure Foundation (IRCCS), Hospital Maggiore Policlinico, University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.22429DOI Listing
September 2008

HFE mutations in nonalcoholic fatty liver disease.

Hepatology 2008 May;47(5):1794-5; author reply 1795-6

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.22059DOI Listing
May 2008

Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis.

Diabetes 2008 May 3;57(5):1355-62. Epub 2008 Mar 3.

Department of Internal Medicine, Ospedale Maggiore Policlinico Mangiagalli Regina Elena IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db07-0714DOI Listing
May 2008

Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver.

Am J Pathol 2008 Mar 2;172(3):738-47. Epub 2008 Feb 2.

Department of Internal Medicine, Ospedale Maggiore Policlinico Mangiagalli Regina Elena Istituto Ricovero e Cura a Carattere Scientifico, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2008.070097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258266PMC
March 2008

Iron genes, dysmetabolism and fibrosis in chronic hepatitis C.

J Hepatol 2008 Mar 31;48(3):513-4; author reply 514-5. Epub 2007 Dec 31.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2007.12.001DOI Listing
March 2008

The hand arthropathy of hereditary hemochromatosis is strongly associated with iron overload.

J Rheumatol 2008 Jan;35(1):153-8

Department of Internal Medicine, Medicina Interna IB, Universita' di Milano, Ospedale Policlinico Mangiagalli Regina Elena IRCCS, Milano, Italy.

View Article

Download full-text PDF

Source
http://www.jrheum.org/content/35/1/153.full.pdf
Web Search
January 2008

HFE genotype influences erythropoiesis support requirement in hemodialysis patients: a prospective study.

Am J Nephrol 2008 16;28(2):311-6. Epub 2007 Nov 16.

Department of Internal Medicine, University of Milan, Ospedale Policlinico Mangiagalli e Regina Elena Fondazione IRCCS, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000111387DOI Listing
May 2008

Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis.

Haematologica 2007 Aug 20;92(8):1037-42. Epub 2007 Jul 20.

Department of Internal Medicine, Medicina Interna IB, Universita' di Milano, Ospedale Policlinico Mangiagalli Regina Elena IRCCS, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.11281DOI Listing
August 2007

Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: evidence from a case-control study.

Am J Gastroenterol 2007 Jun 27;102(6):1251-8. Epub 2007 Mar 27.

Department of Internal Medicine, Universita' di Milano, Ospedale Policlinico Mangiagalli Regina Elena IRCCS, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1572-0241.2007.01192.xDOI Listing
June 2007

HFE gene mutations and oxidative stress influence serum ferritin, associated with vascular damage, in hemodialysis patients.

Am J Nephrol 2007 13;27(1):101-7. Epub 2007 Feb 13.

Department of Internal Medicine, University of Milano, Ospedale Policlinico Mangiagalli e Regina Elena Fondazione IRCCS, Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000099635DOI Listing
April 2007

TNFalpha genotype affects TNFalpha release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis.

J Hepatol 2005 Dec 5;43(6):944-50. Epub 2005 Jul 5.

Dipartimento di Medicina Interna, Ospedale Maggiore IRCCS, Università degli Studi, Pad Granelli, Via F Sforza 35, 20122 Milano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2005.05.035DOI Listing
December 2005

Treatment choices for people infected with HCV.

J Antimicrob Chemother 2004 May 8;53(5):708-12. Epub 2004 Apr 8.

Dipartimento di Medicina Interna, Ospedale Maggiore IRCCS, Università di Milano, Via F Sforza 35, 20122 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkh170DOI Listing
May 2004

TNFalpha promoter polymorphisms.

Methods Mol Med 2004 ;98:47-58

Department of Internal Medicine, Universitá delgi Studi, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1385/1-59259-771-8:047DOI Listing
April 2004

Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development.

J Hepatol 2003 Aug;39(2):208-14

Department of Medicine, Gastroenterology Unit, Ospedale Fatebenefratelli, C.so Porta Nuova 23, 20121, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0168-8278(03)00190-9DOI Listing
August 2003

Levels of uroporphyrinogen decarboxylase (URO-D) in erythrocytes of Italian porphyria cutanea tarda patients.

Cell Mol Biol (Noisy-le-grand) 2002 Feb;48(1):27-32

Centro Anemie Congenite, IRCCS Ospedale Maggiore Policlinico, Padiglione Granelli, Dipartimento di Medicina Intema, Università degli Studi di Milano, Italy.

View Article

Download full-text PDF

Source
February 2002