Anna Kostareva

Anna Kostareva

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Anna Kostareva

Publications by authors named "Anna Kostareva"

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Desmin mutations result in mitochondrial dysfunction regardless of their aggregation properties.

Biochim Biophys Acta Mol Basis Dis 2020 Jun 25;1866(6):165745. Epub 2020 Feb 25.

Almazov National Medical Research Centre, Saint Petersburg, Russia; Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbadis.2020.165745DOI Listing
June 2020

Corrigendum to "Notch signaling in the pathogenesis of thoracic aortic aneurysms: A bridge between embryonic and adult states" [Biochim. Biophys. Acta Mol. Basis Dis. 1866 (3) (Mar 1 2020) 165631].

Biochim Biophys Acta Mol Basis Dis 2020 Jun 27;1866(6):165732. Epub 2020 Feb 27.

Almazov National Medical Research Centre, Akkuratova, 2, 197341 Saint Petersburg, Russia.

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http://dx.doi.org/10.1016/j.bbadis.2020.165732DOI Listing
June 2020

Notch signaling in the pathogenesis of thoracic aortic aneurysms: A bridge between embryonic and adult states.

Biochim Biophys Acta Mol Basis Dis 2020 Mar 6;1866(3):165631. Epub 2019 Dec 6.

Almazov National Medical Research Centre, Akkuratova, 2, 197341 Saint Petersburg, Russia.

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http://dx.doi.org/10.1016/j.bbadis.2019.165631DOI Listing
March 2020

Generation of two induced pluripotent stem cell lines (FAMRCi005-A and FAMRCi005-B) from patient carrying genetic variant LMNA p.Asp357Val.

Stem Cell Res 2020 Mar 5;43:101719. Epub 2020 Feb 5.

Saint Petersburg State University, Saint-Petersburg, Russian Federation; Almazov National Medical Research Centre, Saint-Petersburg, Russian Federation; Institute of Cytology RAS, Saint-Petersburg, Russian Federation.

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http://dx.doi.org/10.1016/j.scr.2020.101719DOI Listing
March 2020

Dose-dependent mechanism of Notch action in promoting osteogenic differentiation of mesenchymal stem cells.

Cell Tissue Res 2020 Jan 28;379(1):169-179. Epub 2019 Nov 28.

Almazov Federal Medical Research Centre, Akkuratova, 2, St. Petersburg, 197341, Russia.

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http://dx.doi.org/10.1007/s00441-019-03130-7DOI Listing
January 2020

Characterization of a novel SCN5A genetic variant A1294G associated with mixed clinical phenotype.

Biochem Biophys Res Commun 2019 Aug 26;516(3):777-783. Epub 2019 Jun 26.

Almazov National Medical Research Centre, Saint-Petersburg, Russia; Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2019.06.080DOI Listing
August 2019

The Notch pathway: a novel therapeutic target for cardiovascular diseases?

Expert Opin Ther Targets 2019 08 14;23(8):695-710. Epub 2019 Jul 14.

Laboratory of Molecular Cardiology, Almazov National Medical Research Centre , St-Petersburg , Russia.

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http://dx.doi.org/10.1080/14728222.2019.1641198DOI Listing
August 2019

Release of Mitochondrial and Nuclear DNA During On-Pump Heart Surgery: Kinetics and Relation to Extracellular Vesicles.

J Cardiovasc Transl Res 2019 06 12;12(3):184-192. Epub 2018 Dec 12.

Division of Physiology, Department of Molecular Medicine, Institute of Basic Medical Science, University of Oslo, Postbox 1103, Blindern, 0317, Oslo, Norway.

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http://dx.doi.org/10.1007/s12265-018-9848-3DOI Listing
June 2019

Human aortic endothelial cells have osteogenic Notch-dependent properties in co-culture with aortic smooth muscle cells.

Biochem Biophys Res Commun 2019 Jun 2;514(2):462-468. Epub 2019 May 2.

Almazov Federal Medical Research Centre, Saint-Petersburg, Russia; Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, Russia; Saint-Petersburg State University, Saint-Petersburg, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.04.177DOI Listing
June 2019

Tissue-Specific Influence of Lamin A Mutations on Notch Signaling and Osteogenic Phenotype of Primary Human Mesenchymal Cells.

Cells 2019 03 21;8(3). Epub 2019 Mar 21.

Almazov National Medical Research Centre, 2 Akkuratova Str., St-Petersburg 197341, Russia.

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http://dx.doi.org/10.3390/cells8030266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468400PMC
March 2019

Notch, BMP and WNT/β-catenin network is impaired in endothelial cells of the patients with thoracic aortic aneurysm.

Atheroscler Suppl 2018 Sep 25;35:e6-e13. Epub 2018 Aug 25.

Almazov Federal Medical Research Centre, Akkuratova, 2, 197341, Saint-Petersburg, Russia; Saint-Petersburg State University, Universitetskaya nab., 7/9, St. Petersburg, 199034, Russia; ITMO University, Institute of Translational Medicine, 49 Kronverksky Pr., St. Petersburg, 197101, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosissup.2018.08.002DOI Listing
September 2018

Relationship Between Vitamin D Status and Vitamin D Receptor Gene Polymorphisms With Markers of Metabolic Syndrome Among Adults.

Front Endocrinol (Lausanne) 2018 16;9:448. Epub 2018 Aug 16.

Department of Biochemistry, Radioimmunology and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland.

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http://dx.doi.org/10.3389/fendo.2018.00448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106967PMC
August 2018

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland.

Am J Hum Genet 2018 05 26;102(5):760-775. Epub 2018 Apr 26.

Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki 00014, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986696PMC
May 2018

Assaying Mitochondrial Respiration as an Indicator of Cellular Metabolism and Fitness.

Methods Mol Biol 2017 ;1601:79-87

Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-6960-9_7DOI Listing
February 2018

Structural consequences of mutations associated with idiopathic restrictive cardiomyopathy.

Amino Acids 2017 Nov 22;49(11):1815-1829. Epub 2017 Aug 22.

Department of Bioinformatics, Peter the Great Saint Petersburg Polytechnic University, St. Petersburg, 195251, Russian Federation.

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http://dx.doi.org/10.1007/s00726-017-2480-8DOI Listing
November 2017

Generation of iPSC line from desmin-related cardiomyopathy patient carrying splice site mutation of DES gene.

Stem Cell Res 2017 10 19;24:77-80. Epub 2017 Aug 19.

Federal Almazov North-West Medical Research Centre, Saint-Petersburg, Russia; ITMO University, Saint-Petersburg, Russia; Department of Women's and Children's Health, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.scr.2017.08.015DOI Listing
October 2017

Generation of iPSC line from patient with arrhythmogenic right ventricular cardiomyopathy carrying mutations in PKP2 gene.

Stem Cell Res 2017 10 18;24:85-88. Epub 2017 Aug 18.

Federal Almazov North-West Medical Research Centre, Saint-Petersburg, Russia; ITMO University, Saint-Petersburg, Russia; Saint Petersburg State University, Saint-Petersburg, Russia.

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http://dx.doi.org/10.1016/j.scr.2017.08.014DOI Listing
October 2017

Progressive cardiac conduction disease associated with a DSP gene mutation.

Int J Cardiol 2016 Aug 30;216:188-9. Epub 2016 Apr 30.

Almazov Federal Medical Research Centre, St. Petersburg, Russia; Department of Woman and Child Health and Centre for Molecular Medicine, Karolinska Institute, Stockholm, Sweden; ITMO University, Institute of translational Medicine, St. Petersburg, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.04.164DOI Listing
August 2016

Primary Murine Myotubes as a Model for Investigating Muscular Dystrophy.

Biomed Res Int 2015 24;2015:594751. Epub 2015 Aug 24.

Department of Women's and Children's Health, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden ; Center for Molecular Medicine, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden.

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http://dx.doi.org/10.1155/2015/594751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561302PMC
June 2016

Various lamin A/C mutations alter expression profile of mesenchymal stem cells in mutation specific manner.

Mol Genet Metab 2015 Jun-Jul;115(2-3):118-27. Epub 2015 May 6.

Almazov Federal Medical Research Centre, St. Petersburg, Russia; Department of Woman and Child Health, Centre for Molecular Medicine, Karolinska Institute, Stockholm, Sweden; ITMO University, Institute of translational Medicine, St. Petersburg, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2015.04.006DOI Listing
March 2016

Ring chromosome 18 in combination with 18q12.1 (DTNA) interstitial microdeletion in a patient with multiple congenital defects.

Mol Cytogenet 2016 18;9:18. Epub 2016 Feb 18.

Almazov Federal Medical Research Centre, Saint-Petersburg, 197341 Russia ; Department of Women's and Children's Health, Center for Molecular Medicine, Karolinska Institute, Stockholm, 17176 Sweden.

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http://dx.doi.org/10.1186/s13039-016-0229-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758088PMC
February 2016

Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms.

Int J Vasc Med 2016 19;2016:3107879. Epub 2016 Jan 19.

Almazov Federal Medical Research Centre, Akkuratova 2, Saint Petersburg 197341, Russia; ITMO University, Institute of Translational Medicine, 49 Kronverksky Prospekt, Saint Petersburg 197101, Russia.

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http://dx.doi.org/10.1155/2016/3107879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745582PMC
February 2016

Congenital heart defects are rarely caused by mutations in cardiac and smooth muscle actin genes.

Biomed Res Int 2015 10;2015:127807. Epub 2015 Mar 10.

Institute of Molecular Biology and Genetics, Federal Almazov Medical Research Centre, 2 Akkuratova Street, Saint-Petersburg 197341, Russia ; Department of Women and Child Health, Karolinska Institute, and Centre for Molecular Medicine, 17176 Stockholm, Sweden.

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http://dx.doi.org/10.1155/2015/127807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377391PMC
December 2015

Beta-catenin in schizophrenia: Possibly deleterious novel mutation.

Psychiatry Res 2015 Aug 19;228(3):843-8. Epub 2015 May 19.

Faculty of Biology, Saint Petersburg State University, Saint Petersburg, Russia; Institute of Experimental Medicine, Northwestern Branch of the Russian Academy of Medical Sciences, Saint Petersburg, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2015.05.014DOI Listing
August 2015

Variants in the NOTCH1 gene in patients with aortic coarctation.

Congenit Heart Dis 2014 Sep-Oct;9(5):391-6. Epub 2014 Jan 12.

Almazov Federal Heart, Blood and Endocrinology Center, St. Petersburg, Russia.

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http://dx.doi.org/10.1111/chd.12157DOI Listing
June 2015

Neonatal hypertrophic cardiomyopathy caused by double mutation in RAS pathway genes.

Int J Cardiol 2015 Apr 24;184:272-3. Epub 2015 Feb 24.

Almazov Federal Medical Research Center, St. Petersburg, Russia; Department of Women's and Children's Health, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2015.02.029DOI Listing
April 2015

Regulation of nutrition-associated receptors in blood monocytes of normal weight and obese humans.

Peptides 2015 Mar 22;65:12-9. Epub 2015 Jan 22.

Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Department of Endocrinology, Diabetes and Nutrition, Campus Benjamin Franklin, Charité University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1016/j.peptides.2014.11.009DOI Listing
March 2015

Aggregate-prone desmin mutations impair mitochondrial calcium uptake in primary myotubes.

Cell Calcium 2014 Oct 10;56(4):269-75. Epub 2014 Aug 10.

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ceca.2014.08.001DOI Listing
October 2014

Early changes of gene expression profiles in the rat model of arterial injury.

J Vasc Interv Radiol 2014 May 6;25(5):789-796.e7. Epub 2014 Feb 6.

Center for Molecular Medicine and Division of Vascular Surgery, Karolinska Institutet, SE-171 76 Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 76 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jvir.2013.11.031DOI Listing
May 2014

Thr92Ala polymorphism of human type 2 deiodinase gene (hD2) affects the development of Graves' disease, treatment efficiency, and rate of remission.

Clin Dev Immunol 2012 12;2012:340542. Epub 2012 Nov 12.

Institute of Endocrinology, Almazov Federal Heart, Blood and Endocrinology Centre, 2 Akkuratova Street, Saint-Petersburg 197541, Russia. alina

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http://dx.doi.org/10.1155/2012/340542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502840PMC
August 2013

Diagnostic challenge in desmin cardiomyopathy with transformation of clinical phenotypes.

Pediatr Cardiol 2013 Feb 7;34(2):467-70. Epub 2012 Apr 7.

Almazov Federal Centre for Heart, Blood and Endocrinology, St Petersburg 197341, Russia.

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http://dx.doi.org/10.1007/s00246-012-0312-xDOI Listing
February 2013

Genetic spectrum of cardiomyopathies with neuromuscular phenotype.

Front Biosci (Schol Ed) 2013 Jan 1;5:325-40. Epub 2013 Jan 1.

Almazov Federal Heart, Blood and Endocrinology Centre, St. Petersburg, Russia.

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http://dx.doi.org/10.2741/s375DOI Listing
January 2013

Type 2 deiodinase Thr92Ala polymorphism impact on clinical course and myocardial remodeling in patients with Graves' disease.

Cell Cycle 2009 Aug;8(16):2565-9

Department of Endocrinology, I.P. Pavlov Saint-Petersburg Medical State University, Saint-Petersburg, Russia.

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http://dx.doi.org/10.4161/cc.8.16.9250DOI Listing
August 2009

Mice expressing L345P mutant desmin exhibit morphological and functional changes of skeletal and cardiac mitochondria.

J Muscle Res Cell Motil 2008 19;29(1):25-36. Epub 2008 Jun 19.

Department of Woman and Child Health and Center for Molecular Medicine, Karolinska Institute, L8:02, Stockholm 17176, Sweden.

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http://link.springer.com/10.1007/s10974-008-9139-8
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http://dx.doi.org/10.1007/s10974-008-9139-8DOI Listing
October 2008

Forced expression of desmin and desmin mutants in cultured cells: impact of myopathic missense mutations in the central coiled-coil domain on network formation.

Exp Cell Res 2006 May 7;312(9):1554-65. Epub 2006 Mar 7.

Department of Cardiology, University of Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.yexcr.2006.01.021DOI Listing
May 2006

Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages.

Proc Natl Acad Sci U S A 2005 Oct 10;102(42):15099-104. Epub 2005 Oct 10.

Department of Molecular Genetics, German Cancer Research Center, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.0504568102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1250230PMC
October 2005

[Hereditary cardiomyopathies: a review. Mutation of structural proteins a common cause of hereditary cardiomyopathy].

Lakartidningen 2005 Mar 14-20;102(11):845-7, 850-3

Barnkardiologiska sektionen, Astrid Lindgrens barnsjukhus, Stockholm.

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April 2005