Anna Jauch

Anna Jauch

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Anna Jauch

Anna Jauch

Publications by authors named "Anna Jauch"

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TP53 deficiency permits chromosome abnormalities and karyotype heterogeneity in acute myeloid leukemia.

Leukemia 2019 Nov 23;33(11):2619-2627. Epub 2019 Aug 23.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41375-019-0550-5DOI Listing
November 2019

EASIX for prediction of survival in lower-risk myelodysplastic syndromes.

Blood Cancer J 2019 Nov 11;9(11):85. Epub 2019 Nov 11.

Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41408-019-0247-zDOI Listing
November 2019

Cytogenetic subclone formation and evolution in progressive smoldering multiple myeloma.

Leukemia 2019 Nov 11. Epub 2019 Nov 11.

Medizinische Klinik V, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41375-019-0634-2DOI Listing
November 2019

Micronucleus formation in human cancer cells is biased by chromosome size.

Genes Chromosomes Cancer 2019 06 17;58(6):392-395. Epub 2019 Jan 17.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.22707DOI Listing
June 2019

Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells.

Cell Stem Cell 2019 01 20;24(1):166-182.e13. Epub 2018 Dec 20.

Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), and DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.11.015DOI Listing
January 2019

Cytogenetic abnormalities in monoclonal gammopathy of undetermined significance.

Leukemia 2018 12 6;32(12):2717-2719. Epub 2018 Jul 6.

Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0202-1DOI Listing
December 2018

Cytogenetic aberrations in multiple myeloma are associated with shifts in serum immunoglobulin isotypes distribution and levels.

Haematologica 2018 04 1;103(4):e162-e164. Epub 2018 Feb 1.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.3324/haematol.2017.184226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865437PMC
April 2018

Murine transgenic embryonic stem cell lines for the investigation of sinoatrial node-related molecular pathways.

Stem Cell Res 2017 12 11;25:278-282. Epub 2017 Jul 11.

Institute of Human Genetics, University Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.07.011DOI Listing
December 2017

Hematopoietic stem cells can be separated from leukemic cells in a subgroup of adult acute lymphoblastic leukemia patients.

Leuk Lymphoma 2017 06 13;58(6):1446-1454. Epub 2016 Oct 13.

a Department of Medicine V , University of Heidelberg , Im Neuenheimer Feld 410 , Heidelberg , Germany.

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http://dx.doi.org/10.1080/10428194.2016.1236378DOI Listing
June 2017

Potential therapeutic targets in plasma cell disorders: A flow cytometry study.

Cytometry B Clin Cytom 2017 03 3;92(2):145-152. Epub 2016 Feb 3.

Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/cyto.b.21351DOI Listing
March 2017

Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60/S4 cells.

Nucleus 2017 03;8(2):222-237

d University of New England, College of Pharmacy , Department of Pharmaceutical Sciences , Portland , ME , USA.

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http://dx.doi.org/10.1080/19491034.2017.1285989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403136PMC
March 2017

Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma.

Am J Hematol 2016 Nov 3;91(11):E473-E477. Epub 2016 Sep 3.

Medizinische Klinik V, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ajh.24533DOI Listing
November 2016

Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.

Blood 2016 09 25;128(9):1226-33. Epub 2016 Jul 25.

Max-Eder Group "Experimental Therapies for Hematologic Malignancies," Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany; Department of Internal Medicine V, and.

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http://dx.doi.org/10.1182/blood-2016-02-698092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524534PMC
September 2016

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study.

Blood 2016 07 2;128(4):594-602. Epub 2016 Jun 2.

Amyloidosis Center, and Division of Hematology/Oncology/Rheumatology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany;

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http://dx.doi.org/10.1182/blood-2015-10-676361DOI Listing
July 2016

Interstitial 1p32.1p32.3 deletion in a patient with multiple congenital anomalies.

Am J Med Genet A 2015 Oct 10;167A(10):2406-10. Epub 2015 Jun 10.

Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/ajmg.a.37178DOI Listing
October 2015

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

Nature 2015 Apr 18;520(7548):549-52. Epub 2015 Feb 18.

1] Heidelberg Institute for Stem Cell Technology and Experimental Medicine gGmbH (HI-STEM), 69120 Heidelberg, Germany [2] Deutsches Krebsforschungszentrum (DKFZ), Division of Stem Cells and Cancer, Experimental Hematology Group, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature14131DOI Listing
April 2015

Translocation t(11;14) is associated with adverse outcome in patients with newly diagnosed AL amyloidosis when treated with bortezomib-based regimens.

J Clin Oncol 2015 Apr 16;33(12):1371-8. Epub 2015 Mar 16.

Tilmann Bochtler, Ute Hegenbart, Anja Seckinger, Christoph Kimmich, Hartmut Goldschmidt, Anthony D. Ho, Dirk Hose, and Stefan O. Schönland, Amyloidosis Center, University Hospital Heidelberg; Christina Kunz and Axel Benner, German Cancer Research Center; Martin Granzow and Anna Jauch, Institute of Human Genetics, University Heidelberg; and Hartmut Goldschmidt and Dirk Hose, National Center for Tumor Diseases, Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.2014.57.4947DOI Listing
April 2015

Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin.

Stem Cell Reports 2015 Mar 19;4(3):503-18. Epub 2015 Feb 19.

Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, Germany; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375832PMC
March 2015

High resistance to X-rays and therapeutic carbon ions in glioblastoma cells bearing dysfunctional ATM associates with intrinsic chromosomal instability.

Int J Radiat Biol 2015 Feb 8;91(2):157-65. Epub 2014 Sep 8.

Heidelberg University Hospital, Department of Radiation Oncology and Radiation Therapy , Heidelberg.

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http://dx.doi.org/10.3109/09553002.2014.937511DOI Listing
February 2015

Cell fusion enhances mesendodermal differentiation of human induced pluripotent stem cells.

Stem Cells Dev 2014 Dec 11;23(23):2875-82. Epub 2014 Aug 11.

1 Department of Cell Biology, Institute for Biomedical Engineering, RWTH Aachen University Medical School , Aachen, Germany .

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http://dx.doi.org/10.1089/scd.2014.0120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235980PMC
December 2014

Mosaic deletion of EXOC6B: further evidence for an important role of the exocyst complex in the pathogenesis of intellectual disability.

Am J Med Genet A 2014 Dec 24;164A(12):3088-94. Epub 2014 Sep 24.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ajmg.a.36770DOI Listing
December 2014

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load.

J Clin Oncol 2013 Dec 21;31(34):4325-32. Epub 2013 Oct 21.

Kai Neben, Anna Jauch, Jens Hillengass, Nicola Lehners, Martin Granzow, Marc S. Raab, and Anthony D. Ho, University of Heidelberg; Thomas Hielscher, German Cancer Research Center; and Anja Seckinger, Hartmut Goldschmidt, and Dirk Hose,University of Heidelberg and National Center for Tumor Diseases, Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.2012.48.4923DOI Listing
December 2013

Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia.

Br J Haematol 2013 Nov 27;163(4):496-500. Epub 2013 Aug 27.

Department of Translational Oncology, National Centre for Tumour Diseases (NCT) and German Cancer Research Centre (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1111/bjh.12539DOI Listing
November 2013

Clonal heterogeneity as detected by metaphase karyotyping is an indicator of poor prognosis in acute myeloid leukemia.

J Clin Oncol 2013 Nov 23;31(31):3898-905. Epub 2013 Sep 23.

Tilmann Bochtler, Christoph E. Heilig, Anna Jauch, Johannes W.G. Janssen, Anthony D. Ho, and Alwin Krämer, University of Heidelberg; Tilmann Bochtler, Christina Kunz, Axel Benner, and Alwin Krämer, German Cancer Research Center (DKFZ), Heidelberg; and Friedrich Stölzel, Brigitte Mohr, Michael Kramer, Martin Bornhäuser, Gerhard Ehninger, and Markus Schaich, University Hospital Carl Gustav Carus, Dresden, Germany.

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http://dx.doi.org/10.1200/JCO.2013.50.7921DOI Listing
November 2013

Next-generation sequencing of cancer consensus genes in lymphoma.

Leuk Lymphoma 2013 Aug 14;54(8):1831-5. Epub 2013 Jun 14.

Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.3109/10428194.2013.796053DOI Listing
August 2013

Hepatitis B virus infection is associated with deletion of chromosome 8p in multiple myeloma.

Eur J Haematol 2013 Apr 22;90(4):279-85. Epub 2012 Nov 22.

Clinical Cancer Registry, National Center of Tumor Diseases and German Cancer Research Center, Im Neuenheimer Feld 581, Heidelberg, Germany.

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http://dx.doi.org/10.1111/ejh.12018DOI Listing
April 2013

Mesenchymal stem cells in non-small cell lung cancer--different from others? Insights from comparative molecular and functional analyses.

Lung Cancer 2013 Apr 5;80(1):19-29. Epub 2013 Jan 5.

Department of Thoracic Oncology, Thoraxklinik, University of Heidelberg, Amalienstr. 5, 69126 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2012.12.015DOI Listing
April 2013

Xq22.3-q23 deletion including ACSL4 in a patient with intellectual disability.

Am J Med Genet A 2013 Apr 12;161A(4):860-4. Epub 2013 Mar 12.

Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/ajmg.a.35778DOI Listing
April 2013

Cryptic del/dup aberration of 60.6 Mb at 5q15-5q23.3 predicting adult-onset leukodystrophy.

Eur J Med Genet 2012 Oct 7;55(10):568-72. Epub 2012 Jul 7.

Institut für Humangenetik, Klinikum rechts der Isar, TU München, Trogerstr. 32, 81675 München, Germany.

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http://dx.doi.org/10.1016/j.ejmg.2012.06.010DOI Listing
October 2012

A small terminal deletion 11q in a boy without Jacobsen syndrome: narrowing the critical region for the 11q Jacobsen syndrome phenotype.

Am J Med Genet A 2012 Mar 2;158A(3):680-4. Epub 2012 Feb 2.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ajmg.a.34433DOI Listing
March 2012

The role of fluorescence in situ hybridization and gene expression profiling in myeloma risk stratification.

Srp Arh Celok Lek 2011 Dec;139 Suppl 2:84-9

Medizinische Klinik V, Universitätsklinikum Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.2298/sarh11s2084hDOI Listing
December 2011

Genetic instability and diminished differentiation capacity in long-term cultured mouse neurosphere cells.

Mech Ageing Dev 2010 Feb 13;131(2):124-32. Epub 2010 Jan 13.

Molecular Endocrinology, MKIII, University Clinic Dresden, Fiedlerstr. 42, 01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.mad.2010.01.001DOI Listing
February 2010