Publications by authors named "Anna Goldenberg"

69Publications

Patient safety and quality improvement: Ethical principles for a regulatory approach to bias in healthcare machine learning.

J Am Med Inform Assoc 2020 Jun 25. Epub 2020 Jun 25.

Bioethics Department, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/jamia/ocaa085DOI Listing
June 2020

Machine learning approaches to drug response prediction: challenges and recent progress.

NPJ Precis Oncol 2020 15;4:19. Epub 2020 Jun 15.

Department of Computer Science, University of Toronto, Toronto, ON Canada.

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http://dx.doi.org/10.1038/s41698-020-0122-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296033PMC
June 2020

Authors' reply: Use of ShotSpotter detection technology decreases prehospital time for patients sustaining gunshot wounds.

J Trauma Acute Care Surg 2020 Aug;89(2):e17-e18

Division of Trauma, Department of Surgery, Cooper University Hospital, Camden, New Jersey Department of Surgery, Cooper University Hospital, Camden, New Jersey Department of Surgery, St. Barnabas Hospital, Livingston, New Jersey Department of Medicine, Cooper University Hospital, Camden, New Jersey Camden County Police Department, Camden, New Jersey Division of Trauma, Department of Surgery, Cooper University Hospital, Camden, New Jersey Division of Acute Care Surgery, Department of Surgery, Rutgers Robert Wood Johnson, New Brunswick, New Jersey Division of Trauma, Acute Care and Critical Care Surgery, Department of Surgery, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1097/TA.0000000000002726DOI Listing
August 2020

Applying Machine Learning in Liver Disease and Transplantation: A Comprehensive Review.

Hepatology 2020 Mar 6;71(3):1093-1105. Epub 2020 Mar 6.

Multi Organ Transplant Program, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hep.31103DOI Listing
March 2020

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Nature 2019 10 9;574(7780):707-711. Epub 2019 Oct 9.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-019-1650-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141958PMC
October 2019

Biological embedding of experience: A primer on epigenetics.

Proc Natl Acad Sci U S A 2020 Sep 17;117(38):23261-23269. Epub 2019 Oct 17.

Program in Child and Brain Development, CIFAR, MaRS Centre, Toronto, ON, M5G 1M1, Canada;

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http://dx.doi.org/10.1073/pnas.1820838116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519272PMC
September 2020

Do no harm: a roadmap for responsible machine learning for health care.

Nat Med 2019 09 19;25(9):1337-1340. Epub 2019 Aug 19.

Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41591-019-0548-6DOI Listing
September 2019

Use of ShotSpotter detection technology decreases prehospital time for patients sustaining gunshot wounds.

J Trauma Acute Care Surg 2019 12;87(6):1253-1259

From the Division of Trauma, Department of Surgery (A.G.), Department of Surgery (D.R.), Cooper University Hospital, Camden; Department of Surgery (M.D.), St. Barnabas Hospital, Livingston; Department of Medicine (J.P.G.), Cooper University Hospital; Camden County Police Department (J.S.T.); Division of Trauma, Department of Surgery (K.R.), Cooper University Hospital, Camden; Division of Acute Care Surgery, Department of Surgery (C.B.), Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey; and Division of Trauma, Department of Surgery (J.P.H.), Acute Care and Critical Care Surgery, Penn State College of Medicine, Hershey, Pennsylvania.

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http://dx.doi.org/10.1097/TA.0000000000002483DOI Listing
December 2019

Integrative Pharmacogenomics Analysis of Patient-Derived Xenografts.

Cancer Res 2019 Sep 29;79(17):4539-4550. Epub 2019 May 29.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0349DOI Listing
September 2019

To Embed or Not: Network Embedding as a Paradigm in Computational Biology.

Front Genet 2019 1;10:381. Epub 2019 May 1.

School of Computer Science, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.3389/fgene.2019.00381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504708PMC
May 2019

Infection after penetrating brain injury-An Eastern Association for the Surgery of Trauma multicenter study oral presentation at the 32nd annual meeting of the Eastern Association for the Surgery of Trauma, January 15-19, 2019, in Austin, Texas.

J Trauma Acute Care Surg 2019 07;87(1):61-67

From the Department of Surgery, University of Colorado Anschutz Medical Center (L.A.H.), Aurora, Colorado; Department of Surgery, Trauma, R Adams Cowley Shock Trauma Center (D.J.H., J.A.K., D.M.S.), University of Maryland (S.A.), School of Medicine, Baltimore MD; St Mary's Medical Center, Florida Atlantic University, Charles E. Schmidt School of Medicine (D.C., L.L.), Boca Raton, Florida; Department of Surgery, Carolinas Medical Center (K.W.C.), Charlotte, North Carolina; Department of Surgery, Division of Trauma, Rutgers, The State University of New Jersey (S.B.), Newark New Jersey; Department of Surgery, Division of Trauma, Eastern Virginia Medical School (J.B., J.E., J.L.R.), Norforlk, Virginia; Department of Surgery, Wright State Boonshoft School of Medicine, (G.S.), Beavercreek, Ohio; Department of Surgery, Division of Trauma, Allegheny General Hospital (M.R.N., B.N.C.), Pittsburgh, Pennsylvania; Department of Surgery, Division of Trauma, Methodist Hospital (V.A., M.T.), Dallas, Texas; Department of Surgery, Division of Trauma, Cooper Health (J.M., A.G.), Camden, New Jersey; Banner Health System (M.B., N.K.), Phoenix, Arizona; Department of Surgery, Division of Trauma, Indiana University School of Medicine (P.M.H.), Indianapolis, Indiana; Department of Surgery, Division of Trauma, University of California Irvine (J.N., A.G.), Orange County; Department of Surgery, Division of Trauma, Loma Linda Medical Center (D.T., V.C.), Loma Linda; Department of Surgery, Division of Trauma, LA County Harbor-UCLA Medical Center (P.L., D.K.), Los Angeles, California; Department of Surgery, Division of Trauma, UC Health Northern Colorado (T.C., J.D.), Loveland, Colorado; Medical City Plano Hospital (V.P.), Plano, Texas; and Department of Surgery, Division of Trauma, University of Colorado Health (T.S.), Colorado Springs, Colorado.

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http://dx.doi.org/10.1097/TA.0000000000002327DOI Listing
July 2019

Determining Trajectory to Predict Injury: The Use of X-Ray During Resuscitation in Gunshot Wounds.

J Surg Res 2019 08 9;240:201-205. Epub 2019 Apr 9.

Division of Trauma, Department of Surgery, Cooper University Hospital, Camden, New Jersey. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2019.03.065DOI Listing
August 2019

Dr.VAE: improving drug response prediction via modeling of drug perturbation effects.

Bioinformatics 2019 10;35(19):3743-3751

Department of Computer Science, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btz158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761940PMC
October 2019

Machine Learning for Integrating Data in Biology and Medicine: Principles, Practice, and Opportunities.

Inf Fusion 2019 Oct 21;50:71-91. Epub 2018 Sep 21.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.inffus.2018.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242341PMC
October 2019

Pediatric Major Vascular Injuries: A 16-Year Institutional Experience From a Combined Adult and Pediatric Trauma Center.

Pediatr Emerg Care 2018 Oct 17. Epub 2018 Oct 17.

From the Division of Trauma, Department of Surgery, and.

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http://dx.doi.org/10.1097/PEC.0000000000001642DOI Listing
October 2018

Hypoxia-induced pulmonary vasoconstriction of intra-acinar arteries is impaired in NADPH oxidase 4 gene-deficient mice.

Pulm Circ 2018 Oct-Dec;8(4):2045894018808240. Epub 2018 Oct 4.

1 Institute of Anatomy and Cell Biology, Justus-Liebig-University, Giessen, Germany.

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http://dx.doi.org/10.1177/2045894018808240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236867PMC
October 2018

Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome.

Epigenomics 2018 05 25;10(5):539-557. Epub 2018 Apr 25.

Department of Biological Sciences, University of Toronto, Scarborough, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2217/epi-2017-0150DOI Listing
May 2018

Similarity Network Fusion: A Novel Application to Making Clinical Diagnoses.

Rheum Dis Clin North Am 2018 May 21;44(2):285-293. Epub 2018 Feb 21.

Genetics and Genome Biology, Department of Computer Science, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning (PGCRL), University of Toronto, 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.

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http://dx.doi.org/10.1016/j.rdc.2018.01.005DOI Listing
May 2018

Learning from Everyday Images Enables Expert-like Diagnosis of Retinal Diseases.

Cell 2018 02;172(5):893-895

University of Toronto, Department of Computer Science, Toronto, ON, Canada; The Hospital for Sick Children, Toronto, ON, Canada; Vector Institute, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.02.013DOI Listing
February 2018

Vicus: Exploiting local structures to improve network-based analysis of biological data.

PLoS Comput Biol 2017 Oct 12;13(10):e1005621. Epub 2017 Oct 12.

SickKids Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pcbi.1005621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638230PMC
October 2017

Incorporating networks in a probabilistic graphical model to find drivers for complex human diseases.

PLoS Comput Biol 2017 Oct 12;13(10):e1005580. Epub 2017 Oct 12.

Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pcbi.1005580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638204PMC
October 2017

The inconvenience of data of convenience: computational research beyond post-mortem analyses.

Nat Methods 2017 09;14(10):937-938

Genetics and Genome Biology, SickKids Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nmeth.4457DOI Listing
September 2017

Molecular Signatures for Tumor Classification: An Analysis of The Cancer Genome Atlas Data.

J Mol Diagn 2017 11 1;19(6):881-891. Epub 2017 Sep 1.

Princess Margaret Cancer Centre and MacFeeters-Hamilton Centre for Neuro-Oncology Research, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.07.008DOI Listing
November 2017

Venous thromboembolism after major venous injuries: Competing priorities.

J Trauma Acute Care Surg 2017 12;83(6):1095-1101

From the Department of Surgery, Geisinger Health System (B.F.), Danville; Division of Trauma and Surgical Critical Care, Department of Surgery (Z.M.) and Department of Surgery (E.D., A.L.L.), Temple University School of Medicine, Philadelphia, Pennsylvania; Division of Trauma and Surgical Critical Care, Department of Surgery, Cooper Medical School of Rowan University (J.P.H., A.G.), Camden, New Jersey; Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania (S.R., B.P.S., P.M.R., M.J.S.), Philadelphia, Pennsylvania; and Massachusetts General Hospital (N.N.S.), Boston, Massachusetts.

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http://dx.doi.org/10.1097/TA.0000000000001655DOI Listing
December 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163053PMC
June 2017

Conditional random slope: A new approach for estimating individual child growth velocity in epidemiological research.

Am J Hum Biol 2017 Sep 21;29(5). Epub 2017 Apr 21.

Research Institute and Centre for Global Child Health, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/ajhb.23009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599979PMC
September 2017

Integrative Cancer Pharmacogenomics to Infer Large-Scale Drug Taxonomy.

Cancer Res 2017 06 17;77(11):3057-3069. Epub 2017 Mar 17.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0096DOI Listing
June 2017

Systemic intraoperative anticoagulation during arterial injury repair: Implications for patency and bleeding.

J Trauma Acute Care Surg 2017 04;82(4):680-686

From the Temple University School of Medicine (Z.M., E.D., A.L., H.Z.), Philadelphia; Geisinger Health System (B.F.), Danville, Pennsylvania; Massachusetts General Hospital (N.S.), Boston, Massachusetts; Cooper University (A.G., J.P.H.), Camden, New Jersey; and Perelman School of Medicine, University of Pennsylvania (J.W.C., M.J.S.), Philadelphia, Pennsylvania.

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http://Insights.ovid.com/crossref?an=01586154-201704000-0000
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http://dx.doi.org/10.1097/TA.0000000000001384DOI Listing
April 2017

Safikhani et al. reply.

Nature 2016 11;540(7631):E2-E4

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1038/nature19839DOI Listing
November 2016

Safikhani et al. reply.

Nature 2016 11;540(7631):E11-E12

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.email:

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http://dx.doi.org/10.1038/nature20581DOI Listing
November 2016

Safikhani et al. reply.

Nature 2016 11;540(7631):E6-E8

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1038/nature20172DOI Listing
November 2016

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 10 10;7:13205. Epub 2016 Oct 10.

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http://dx.doi.org/10.1038/ncomms13205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062501PMC
October 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 08 23;7:12460. Epub 2016 Aug 23.

Sage Bionetworks, Seattle, Washington 98115, USA.

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http://dx.doi.org/10.1038/ncomms12460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996969PMC
August 2016

Assessment of pharmacogenomic agreement.

F1000Res 2016 9;5:825. Epub 2016 May 9.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, M5G 1L7, Canada; Department of Computer Science, University of Toronto, Toronto, Ontario, M5S 2E4, Canada.

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http://dx.doi.org/10.12688/f1000research.8705.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926729PMC
July 2016

TensorFlow: Biology's Gateway to Deep Learning?

Cell Syst 2016 01 27;2(1):12-4. Epub 2016 Jan 27.

SickKids Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Computer Science, University of Toronto, 40 St. George Street, Toronto, ON M5S 2E4, Canada. Electronic address:

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http://www.cell.com/cell-systems/pdf/S2405-4712(16)00010-7.p
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http://dx.doi.org/10.1016/j.cels.2016.01.009DOI Listing
January 2016

Sex-specific regulation of weight and puberty by the Lin28/let-7 axis.

J Endocrinol 2016 Mar 23;228(3):179-91. Epub 2015 Dec 23.

Division of EndocrinologyThe Hospital for Sick Children, 555 University Avenue, Toronto ON, M5G 1X8, CanadaDivision of Hematology/OncologyBoston Children's Hospital, Boston, Massachusetts, USADepartments of Pediatrics and Internal MedicineChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USAInstitute for Molecular MedicineFinland (FIMM), University of Helsinki, Helsinki, FinlandGenetics and Genome Biology ProgramThe Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Computer ScienceUniversity of Toronto, Toronto, Ontario, CanadaDepartments of Paediatrics and PhysiologyThe University of Toronto, Toronto, Ontario, Canada Division of EndocrinologyThe Hospital for Sick Children, 555 University Avenue, Toronto ON, M5G 1X8, CanadaDivision of Hematology/OncologyBoston Children's Hospital, Boston, Massachusetts, USADepartments of Pediatrics and Internal MedicineChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USAInstitute for Molecular MedicineFinland (FIMM), University of Helsinki, Helsinki, FinlandGenetics and Genome Biology ProgramThe Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Computer ScienceUniversity of Toronto, Toronto, Ontario, CanadaDepartments of Paediatrics and PhysiologyThe University of Toronto, Toronto, Ontario, Canada

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http://joe.endocrinology-journals.org/content/228/3/179.full
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http://joe.endocrinology-journals.org/lookup/doi/10.1530/JOE
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http://dx.doi.org/10.1530/JOE-15-0360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772724PMC
March 2016

PharmacoGx: an R package for analysis of large pharmacogenomic datasets.

Bioinformatics 2016 04 9;32(8):1244-6. Epub 2015 Dec 9.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btv723DOI Listing
April 2016

Expression and localization of GPR91 and GPR99 in murine organs.

Cell Tissue Res 2016 May 21;364(2):245-62. Epub 2015 Nov 21.

Institute of Anatomy and Cell Biology, Excellence Cluster Cardiopulmonary System, Justus-Liebig-University, Aulweg 123, 35385, Giessen, Germany.

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http://dx.doi.org/10.1007/s00441-015-2318-1DOI Listing
May 2016

JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis.

Bioinformatics 2016 Jan 26;32(2):203-10. Epub 2015 Sep 26.

Department of Computer Science, University of Toronto, M5S 2E4, Toronto, ON, Canada, Genetics and Genome Biology, Hospital for Sick Children, M5G 0A4, Toronto, ON, Canada and.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btv504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708100PMC
January 2016

Similarity network fusion for aggregating data types on a genomic scale.

Nat Methods 2014 Mar 26;11(3):333-7. Epub 2014 Jan 26.

1] Genetics and Genome Biology, SickKids Research Institute, Toronto, Ontario, Canada. [2] Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nmeth.2810DOI Listing
March 2014

A probabilistic approach to explore human miRNA targetome by integrating miRNA-overexpression data and sequence information.

Bioinformatics 2014 Mar 17;30(5):621-8. Epub 2013 Oct 17.

Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Genetics and Genome Biology, SickKids Research Institute, Toronto, Ontario M5G 1L7 and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btt599DOI Listing
March 2014

Identifying cancer specific functionally relevant miRNAs from gene expression and miRNA-to-gene networks using regularized regression.

PLoS One 2013 2;8(10):e73168. Epub 2013 Oct 2.

Department of Computer Science, University of Toronto, Toronto, Ontario, Canada ; Genetics and Genome Biology, SickKids Research Institute, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073168PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788788PMC
June 2014

Labeling nodes using three degrees of propagation.

PLoS One 2012 28;7(12):e51947. Epub 2012 Dec 28.

Department of Computer Science, Stanford University, Palo Alto, CA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051947PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532359PMC
June 2013

iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data.

Genome Res 2013 Mar 29;23(3):519-29. Epub 2012 Nov 29.

Department of Computer Science, University of Toronto, Ontario M5S 2E4, Canada.

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http://dx.doi.org/10.1101/gr.142232.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589540PMC
March 2013

Detecting microRNAs of high influence on protein functional interaction networks: a prostate cancer case study.

BMC Syst Biol 2012 Aug 28;6:112. Epub 2012 Aug 28.

Department of Computer Science, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1186/1752-0509-6-112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490713PMC
August 2012

Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries.

Cardiovasc Res 2012 Mar 2;93(4):702-10. Epub 2012 Jan 2.

Institute of Anatomy and Cell Biology, Excellence Cluster Cardio-Pulmonary System, Justus-Liebig-University, Aulweg 123, 35385 Giessen, Germany.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvr359DOI Listing
March 2012

Mixture model for sub-phenotyping in GWAS.

Pac Symp Biocomput 2012 :363-74

Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.

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December 2013

Transabdominal laparoscopic adrenalectomy of a large adrenal lipoma: A case report and review of literature.

Int J Surg Case Rep 2011 6;2(7):172-4. Epub 2011 Jun 6.

University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Kennedy University Hospital, 42 East Laurel Rd, Stratford, NJ 08084, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S22102612110005
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http://dx.doi.org/10.1016/j.ijscr.2011.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199696PMC
November 2011

Unsupervised detection of genes of influence in lung cancer using biological networks.

Bioinformatics 2011 Nov 28;27(22):3166-72. Epub 2011 Sep 28.

Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada.

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http://bioinformatics.oxfordjournals.org/content/early/2011/
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http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/btr533DOI Listing
November 2011

Predicting node characteristics from molecular networks.

Methods Mol Biol 2011 ;781:399-414

Department of Computer Science, Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, ON, Canada.

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January 2012

Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability.

Am J Physiol Lung Cell Mol Physiol 2009 Nov 14;297(5):L837-45. Epub 2009 Aug 14.

Institute for Anatomy and Cell Biology, Department of Internal Medicine, Justus Liebig University, Aulweg 123, 35385 Giessen, Germany.

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http://dx.doi.org/10.1152/ajplung.90608.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777497PMC
November 2009

Hypoxic vasoconstriction of partial muscular intra-acinar pulmonary arteries in murine precision cut lung slices.

Respir Res 2006 Jun 29;7:93. Epub 2006 Jun 29.

University of Giessen Lung Center, Institute for Anatomy and Cell Biology, Justus-Liebig-University, Giessen, Germany.

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http://dx.doi.org/10.1186/1465-9921-7-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524949PMC
June 2006

Hypoxia-induced increase of endostatin in murine aorta and lung.

Histochem Cell Biol 2006 May 8;125(5):497-508. Epub 2006 Feb 8.

Institute of Anatomy and Cell Biology, Justus-Liebig-University, 35385, Giessen, Germany.

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http://link.springer.com/content/pdf/10.1007/s00418-006-0158
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http://dx.doi.org/10.1007/s00418-006-0158-5DOI Listing
May 2006

Role of ROS and NO in hypoxia-induced increase in tyrosine hydroxylase-messenger RNA in PC12 cells.

Adv Exp Med Biol 2003 ;536:193-9

Institute for Anatomy and Cell Biology, Justus-Liebig-University, 35385 Giessen, Germany.

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http://dx.doi.org/10.1007/978-1-4419-9280-2_25DOI Listing
August 2004

Mitochondrial complex II is essential for hypoxia-induced ROS generation and vasoconstriction in the pulmonary vasculature.

Adv Exp Med Biol 2003 ;536:163-9

Institute for Anatomy and Cell Biology, Justus-Liebig-University, 35385 Giessen, Germany.

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http://dx.doi.org/10.1007/978-1-4419-9280-2_21DOI Listing
August 2004

Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature.

Am J Physiol Lung Cell Mol Physiol 2003 May 10;284(5):L710-9. Epub 2003 Jan 10.

Institute of Anatomy and Cell Biology, Justus Liebig University, 35385 Giessen, Germany.

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http://dx.doi.org/10.1152/ajplung.00149.2002DOI Listing
May 2003

Early statistical detection of anthrax outbreaks by tracking over-the-counter medication sales.

Proc Natl Acad Sci U S A 2002 Apr;99(8):5237-40

Center for Automated Learning and Discovery, Carnegie Mellon University, Pittsburgh, PA 15213-3890, USA.

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http://dx.doi.org/10.1073/pnas.042117499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122753PMC
April 2002