Anna Garuti

Lipoprotein(a) concentration, genetic variants, apo(a) isoform size, and cellular cholesterol efflux in patients with elevated Lp(a) and coronary heart disease submitted or not to lipoprotein apheresis: An Italian case-control multicenter study on Lp(a).

Authors:

Claudia Stefanutti Livia Pisciotta Elda Favari Serafina Di Giacomo Federica Vacondio Maria Grazia Zenti Claudia Morozzi Daniele Berretti Dario Mesce Marco Vitale Andrea Pasta Annalisa Ronca Anna Garuti Matteo Manfredini Eduardo Anglés-Cano Santica Marija Marcovina Gerald Francis Watts

J Clin Lipidol 2020 Jul - Aug;14(4):487-497.e1. Epub 2020 May 19.

School of Medicine, Faculty of Health and Medical Sciences - Cardiometabolic Service, Department of Cardiology, Royal Perth Hospital University of Western Australia, Perth, Western Australia, Australia.

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May 2020

Optimization of a WGA-Free Molecular Tagging-Based NGS Protocol for CTCs Mutational Profiling.

Authors:

Giuseppa De Luca Barbara Cardinali Lucia Del Mastro Sonia Lastraioli Franca Carli Manlio Ferrarini George A Calin Anna Garuti Carlotta Mazzitelli Simona Zupo Mariella Dono

Int J Mol Sci 2020 Jun 19;21(12). Epub 2020 Jun 19.

Molecular Diagnostic Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.

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June 2020

Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy.

Authors:

Gabriella Cirmena Anna Garuti Marilena De Mariano Simona Coco Lorenzo Ferrando Edoardo Isnaldi Valentina Barbero Piero Fregatti Lucia Del Mastro Fabio Ferrando Roberta Gonella Alessandro Garlaschi Daniele Friedman Alberto Ballestrero Gabriele Zoppoli

J Oncol 2020 22;2020:8132507. Epub 2020 Jan 22.

Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy.

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January 2020

Development of a long non-coding RNA signature for prediction of response to neoadjuvant chemoradiotherapy in locally advanced rectal adenocarcinoma.

Authors:

Lorenzo Ferrando Gabriella Cirmena Anna Garuti Stefano Scabini Federica Grillo Luca Mastracci Edoardo Isnaldi Ciro Marrone Roberta Gonella Roberto Murialdo Roberto Fiocca Emanuele Romairone Alberto Ballestrero Gabriele Zoppoli

PLoS One 2020 5;15(2):e0226595. Epub 2020 Feb 5.

Department of Internal Medicine, Università degli Studi di Genova, Genova, Italy.

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April 2020

Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer.

Authors:

Edoardo Isnaldi Anna Garuti Gabriella Cirmena Stefano Scabini Edoardo Rimini Lorenzo Ferrando Michela Lia Roberto Murialdo Lucia Tixi Enrico Carminati Andrea Panaro Maurizio Gallo Federica Grillo Luca Mastracci Lazzaro Repetto Roberto Fiocca Emanuele Romairone Gabriele Zoppoli Alberto Ballestrero

J Transl Med 2019 04 29;17(1):137. Epub 2019 Apr 29.

Department of Internal Medicine (Di.M.I.), University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy.

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April 2019

A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation.

Authors:

Bianca Sparatore Marco Pedrazzi Anna Garuti Alice Franchi Monica Averna Alberto Ballestrero Roberta De Tullio

Biochim Biophys Acta Mol Cell Res 2019 08 5;1866(8):1260-1271. Epub 2019 Apr 5.

Department of Experimental Medicine (DIMES), Biochemistry Section, University of Genova, Viale Benedetto XV, 1-16132 Genova, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV, 7-16132 Genova, Italy. Electronic address:

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August 2019

Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases.

Authors:

Gabriele Zoppoli Anna Garuti Gabriella Cirmena Ludovica Verdun di Cantogno Cristina Botta Maurizio Gallo Domenico Ferraioli Enrico Carminati Paola Baccini Monica Curto Piero Fregatti Edoardo Isnaldi Michela Lia Roberto Murialdo Daniele Friedman Anna Sapino Alberto Ballestrero

J Transl Med 2017 05 1;15(1):91. Epub 2017 May 1.

Department of Internal Medicine (Di.M.I.), University of Genoa and IRCCS AOU San Martino-IST, Viale Benedetto XV, 6, 16132, Genoa, Italy.

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May 2017

Moderate Increase of Indoxyl Sulfate Promotes Monocyte Transition into Profibrotic Macrophages.

Authors:

Chiara Barisione Silvano Garibaldi Anna Lisa Furfaro Mariapaola Nitti Daniela Palmieri Mario Passalacqua Anna Garuti Daniela Verzola Alessia Parodi Pietro Ameri Paola Altieri Patrizia Fabbi Pier Francesco Ferrar Claudio Brunelli Violeta Arsenescu Manrico Balbi Domenico Palombo Giorgio Ghigliotti

PLoS One 2016 29;11(2):e0149276. Epub 2016 Feb 29.

Division of Cardiology, IRCCS University Hospital San Martino, Research Centre of Cardiovascular Biology, University of Genova, Genova, Italy.

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July 2016

Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer.

Authors:

David N Brown Irene Caffa Gabriella Cirmena Daniela Piras Anna Garuti Maurizio Gallo Saverio Alberti Alessio Nencioni Alberto Ballestrero Gabriele Zoppoli

Sci Rep 2016 Jan 18;6:19435. Epub 2016 Jan 18.

Department of Internal Medicine (Di.M.I.), University of Genova, Genova IT.

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January 2016

Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.

Authors:

Paola Altieri Chiara Barisione Edoardo Lazzarini Anna Garuti Gian Paolo Bezante Marco Canepa Paolo Spallarossa Carlo Gabriele Tocchetti Sveva Bollini Claudio Brunelli Pietro Ameri

J Am Heart Assoc 2016 Jan 8;5(1). Epub 2016 Jan 8.

Laboratory of Cardiovascular Biology, Department of Internal Medicine, University of Genova, Italy (P.A., C.B., E.L., G.P.B., M.C., P.S., C.B., P.A.).

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January 2016

A combination of immunohistochemistry and molecular approaches improves highly sensitive detection of BRAF mutations in papillary thyroid cancer.

Authors:

Claudia Martinuzzi Lorenza Pastorino Virginia Andreotti Anna Garuti Michele Minuto Roberto Fiocca Giovanna Bianchi-Scarrà Paola Ghiorzo Federica Grillo Luca Mastracci

Endocrine 2016 Sep 22;53(3):672-80. Epub 2015 Aug 22.

Department of Surgical Sciences (DISC), University of Genoa, Genoa, Italy.

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September 2016

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells.

Clin Cancer Res 2015 Sep 11;21(17):3934-45. Epub 2015 May 11.

Department of Hematology and Oncology, IRCCS AOU S. Martino-IST, Genoa, Italy. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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September 2015

Uncovering the genomic heterogeneity of multifocal breast cancer.

J Pathol 2015 Aug 7;236(4):457-66. Epub 2015 May 7.

Breast Cancer Translational Research Laboratory, Université Libre de Bruxelles, Institut Jules Bordet, Boulevard de Waterloo 121, Brussels, Belgium.

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August 2015

Afatinib resistance in non-small cell lung cancer involves the PI3K/AKT and MAPK/ERK signalling pathways and epithelial-to-mesenchymal transition.

Authors:

Simona Coco Anna Truini Angela Alama Maria Giovanna Dal Bello Roberta Venè Anna Garuti Enrico Carminati Erika Rijavec Carlo Genova Giulia Barletta Claudio Sini Alberto Ballestrero Francesco Boccardo Francesco Grossi

Target Oncol 2015 Sep 25;10(3):393-404. Epub 2014 Oct 25.

Lung Cancer Unit, IRCCS AOU San Martino-IST, L.go R. Benzi 10, 16132, Genoa, Italy,

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September 2015

Quantitative Real Time PCR assessment of hormonal receptors and HER2 status on fine-needle aspiration pre-operatory specimens from a prospectively accrued cohort of women with suspect breast malignant lesions.

Authors:

Anna Garuti Ilaria Rocco Gabriella Cirmena Maurizio Chiaramondia Paola Baccini Massimo Calabrese Claudia Palermo Daniele Friedman Gabriele Zoppoli Alberto Ballestrero

Gynecol Oncol 2014 Feb 21;132(2):389-96. Epub 2013 Nov 21.

Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino Istituto Nazionale Tumori (IST), Genoa, Italy.

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February 2014

Evaluating treatment response of chronic myeloid leukemia: emerging science and technology.

Authors:

Antonia Cagnetta Anna Garuti Carlo Marani Michele Cea Maurizio Miglino Ilaria Rocco Claudia Palermo Giuseppina Fugazza Gabriella Cirmena Nicoletta Colombo Raffaella Grasso Alessio Nencioni Marco Gobbi Franco Patrone

Curr Cancer Drug Targets 2013 Sep;13(7):779-90

Department of Medical Oncology, Dana-Farber Cancer Institute, M551, 450 Brookline Avenue, Boston, MA 02115, USA.

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September 2013

Inhibition of doxorubicin-induced senescence by PPARδ activation agonists in cardiac muscle cells: cooperation between PPARδ and Bcl6.

Authors:

Paola Altieri Paolo Spallarossa Chiara Barisione Silvano Garibaldi Anna Garuti Patrizia Fabbi Giorgio Ghigliotti Claudio Brunelli

PLoS One 2012 25;7(9):e46126. Epub 2012 Sep 25.

Research Centre of Cardiovascular Biology, University of Genova, Genova, Italy.

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April 2013

Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status.

Authors:

Michele Cea Antonia Cagnetta Gabriella Cirmena Anna Garuti Ilaria Rocco Claudia Palermo Ivana Pierri Daniele Reverberi Alessio Nencioni Alberto Ballestrero Marco Gobbi Angelo Michele Carella Franco Patrone

Leuk Lymphoma 2013 Feb 5;54(2):342-52. Epub 2012 Sep 5.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA.

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February 2013

β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.

Authors:

Alessandra Piccini Roberta Borghi Michela Guglielmotto Elena Tamagno Gabriella Cirmena Anna Garuti Valeria Pollero Sergio Cammarata Michele Fornaro Massimo Messa Laura Colombo Mario Salmona George Perry Massimo Tabaton

J Neurochem 2012 Sep 11;122(5):1023-31. Epub 2012 Jul 11.

Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy.

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September 2012

Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction.

Antioxid Redox Signal 2013 Feb 14;18(6):630-41. Epub 2012 May 14.

Division of Cardiology, Foundation for Medical Researches, Faculty of Medicine, Department of Internal Medicine, Geneva University Hospitals, Geneva, Switzerland.

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February 2013

High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas.

Authors:

Maria Raffaella Zocchi Silvia Catellani Paolo Canevali Sara Tavella Anna Garuti Barbara Villaggio Annalisa Zunino Marco Gobbi Giulio Fraternali-Orcioni Annalisa Kunkl Jean-Louis Ravetti Silvia Boero Alessandra Musso Alessandro Poggi

Blood 2012 Feb 13;119(6):1479-89. Epub 2011 Dec 13.

Division of Immunology, Transplants and Infectious Diseases, San Raffaele Scientific Institute, Via Olgettina 60, Milan, Italy.

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February 2012

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.

Bioorg Med Chem 2011 Dec 30;19(24):7720-7. Epub 2011 Jul 30.

Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Federal Institute of Technology (EPFL), Batochime, CH-1015 Lausanne, Switzerland.

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December 2011

Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.

PLoS One 2011 27;6(7):e22739. Epub 2011 Jul 27.

Department of Internal Medicine, University of Genoa, Genoa, Italy.

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December 2011

Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease.

Authors:

Roberta Borghi Alessandra Piccini Erica Barini Gabriella Cirmena Michela Guglielmotto Elena Tamagno Michele Fornaro George Perry Mark A Smith Anna Garuti Massimo Tabaton

J Alzheimers Dis 2010 ;22(3):771-5

Department of Internal Medicine, University of Genova, Genova, Italy.

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June 2011

Engagement of CD31 delivers an activating signal that contributes to the survival of chronic lymphocytic leukaemia cells.

Authors:

Alessandro Poggi Claudia Prevosto Silvia Catellani Ilaria Rocco Anna Garuti Maria R Zocchi

Br J Haematol 2010 Nov 31;151(3):252-64. Epub 2010 Aug 31.

Laboratory of Molecular Oncology and Angiogenesis, National Institute for Cancer Research, University of Genoa, Italy.

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November 2010

A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib.

Authors:

Michele Cea Gabriella Cirmena Anna Garuti Ilaria Rocco Claudia Palermo Antonia Cagnetta Eva Moran Nicoletta Colombo Raffaella Grasso Giuseppina Fugazza Marco Gobbi Alessio Nencioni Alberto Ballestrero Franco Patrone

Leuk Res 2010 Sep 5;34(9):e240-2. Epub 2010 May 5.

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September 2010

Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies.

Authors:

Claudia Bello Michele Cea Giovanna Dal Bello Anna Garuti Ilaria Rocco Gabriella Cirmena Eva Moran Aimable Nahimana Michel A Duchosal Floriana Fruscione Paolo Pronzato Francesco Grossi Franco Patrone Alberto Ballestrero Marc Dupuis Bernard Sordat Alessio Nencioni Pierre Vogel

Bioorg Med Chem 2010 May 9;18(9):3320-34. Epub 2010 Mar 9.

Laboratory of Glycochemistry and Asymmetric Synthesis (LGSA), Ecole Polytechnique Fédérale de Lausanne (EPFL), Batochime, CH-1015 Lausanne, Switzerland.

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May 2010