Publications by authors named "Anna Gan"

14Publications

Mutation signatures implicate aristolochic acid in bladder cancer development.

Genome Med 2015 28;7(1):38. Epub 2015 Apr 28.

Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, 8 College Road, Singapore, 169857 Singapore ; Centre for Computational Biology, Duke-NUS Graduate Medical School, 8 College Road, Singapore, 169857 Singapore.

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http://dx.doi.org/10.1186/s13073-015-0161-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443665PMC
May 2015

Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas.

Eur Urol 2015 Jul 14;68(1):77-83. Epub 2015 Jan 14.

Centre for Computational Biology, Duke-NUS Graduate Medical School, Singapore; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.12.040DOI Listing
July 2015

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.

J Clin Endocrinol Metab 2015 Feb 11;100(2):E360-4. Epub 2014 Nov 11.

Laboratory of Cancer Epigenome (W.Y., H.L.H., A.G., D.H., S.L.P., C.K.O., B.T.T.), Division of Medical Sciences, National Cancer Centre Singapore, 169610 Singapore; Division of Cancer and Stem Cell Biology (W.Y., J.R.M., H.L.H., D.H., S.L.P., C.K.O., S.G.R., P.T., B.T.T.), Duke-National University of Singapore Graduate Medical School, 169857 Singapore; National University of Singapore Graduate School for Integrative Sciences and Engineering (W.Y.), 117456 Singapore; Academic Endocrine Unit, Nuffield Department of Clinical Medicine (M.S., P.N., R.V.T.), Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, OX3 7LJ Oxford, United Kingdom; Department of Pathology (R.v.E., D.R., T.v.W., H.M.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Molecular Endocrinology Group, Molecular Pathobiology Research Centre Unit (U.I.P.M.) (B.C.) of the Portuguese Institute of Oncology from Lisbon Francisco Gentil (IPOLFG) and Chronic Diseases Research Centre (CEDOC), Faculty of Medical Sciences (FCM), New University of Lisbon (UNL), 1099-023 Lisbon, Portugal; Genome Institute of Singapore (P.T.), 138672 Singapore; and Cancer Science Institute of Singapore (P.T., B.T.T.), National University of Singapore, 117599 Singapore.

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http://dx.doi.org/10.1210/jc.2014-3238DOI Listing
February 2015

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.

Gut 2015 May 22;64(5):707-19. Epub 2014 Jul 22.

Cancer and Stem Cell Biology program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore Genome Institute of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1136/gutjnl-2013-306596DOI Listing
May 2015

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.

Nat Genet 2013 Dec 3;45(12):1474-8. Epub 2013 Nov 3.

1] Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore. [2] Division of Cancer and Stem Cell Biology, Duke-National University of Singapore Graduate Medical School, Singapore. [3] Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. [4].

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http://www.nature.com/articles/ng.2806
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http://dx.doi.org/10.1038/ng.2806DOI Listing
December 2013