Ann Saunders

Ann Saunders

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Ann Saunders

Publications by authors named "Ann Saunders"

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Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease.

Chromosome Res 2018 03 19;26(1-2):93-111. Epub 2018 Feb 19.

Zinfandel Pharmaceuticals Inc, Chapel Hill, NC, 27709, USA.

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http://dx.doi.org/10.1007/s10577-018-9573-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857278PMC
March 2018

Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.

Alzheimers Dement 2017 Dec 15;13(12):1380-1388. Epub 2017 Jun 15.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723540PMC
December 2017

The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease.

Biochim Biophys Acta Mol Basis Dis 2017 11 30;1863(11):2973-2986. Epub 2017 Jul 30.

Duke University, Department of Neurology, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.07.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659897PMC
November 2017

The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease.

Alzheimers Dement 2017 Jul 24;13(7):828-838. Epub 2017 Feb 24.

Department of Neurology, Duke University School of Medicine, Durham, NC, USA; Zinfandel Pharmaceuticals, Inc, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.jalz.2017.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647845PMC
July 2017

'523 variant and cognitive decline in older persons with ε3/3 genotype.

Neurology 2017 Feb 20;88(7):661-668. Epub 2017 Jan 20.

From the Rush Alzheimer's Disease Center (L.Y., R.S.W., C.G., L.L.B., D.A.B.) and Department of Neurological Sciences (L.Y., R.S.W., C.G., L.L.B., D.A.B.), Rush University Medical Center, Chicago, IL; Department of Neurology (M.W.L., A.D.R., A.M.S.), Duke University School of Medicine, Durham; Zinfandel Pharmaceuticals, Inc (D.K.B., A.D.R.), Research Triangle Park, NC; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital; Harvard Medical School (P.L.D.), Boston; and Program in Medical and Population Genetics (P.L.D.), Broad Institute, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000003614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317377PMC
February 2017

Personality Change Due to Traumatic Brain Injury in Children and Adolescents: Neurocognitive Correlates.

J Neuropsychiatry Clin Neurosci 2015 17;27(4):272-9. Epub 2015 Jul 17.

From the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).

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http://dx.doi.org/10.1176/appi.neuropsych.15030073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618043PMC
September 2016

60 seconds with Ann Saunders.

Authors:
Ann Saunders

Nurs Times 2016 Jun 22-28;112(25):25

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September 2016

Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease.

Alzheimers Dement 2016 06 4;12(6):687-94. Epub 2016 May 4.

Department of Neurology, Duke University School of Medicine, Durham, NC, USA; Semillon Pharmaceuticals, Inc., Chapel Hill, NC, USA.

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http://dx.doi.org/10.1016/j.jalz.2016.03.015DOI Listing
June 2016

The developmental expression of the CDK inhibitor p57(kip2) (Cdkn1c) in the early mouse placenta.

Mol Reprod Dev 2016 05 28;83(5):405-12. Epub 2016 Apr 28.

Department of Pediatrics, Brown University, Women and Infants Hospital of Rhode Island, Providence, Rhode Island.

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http://dx.doi.org/10.1002/mrd.22637DOI Listing
May 2016

Psychiatric disorders in children and adolescents 24 months after mild traumatic brain injury.

J Neuropsychiatry Clin Neurosci 2015 ;27(2):112-20

From the Dept. of Psychiatry, UC San Diego, San Diego, CA, and Rady Children's Hospital, San Diego, CA (JEM); Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel (KF); Baylor College of Medicine, Houston, TX (EAW); Brigham Young University, Provo, UT (EDB); University of Toronto, Toronto, Canada (RJS); University of Texas Health Science Center, Houston, TX (AS); University of Toronto, Toronto, Canada (MD [deceased]; University of Texas Health Science Center, Houston, TX (LE-C); University of Texas, Dallas, TX (SBC); University of California, San Francisco, CA (TTY); Baylor College of Medicine, Houston, TX (HSL).

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http://dx.doi.org/10.1176/appi.neuropsych.13080190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007244PMC
January 2016

A Genetics-based Biomarker Risk Algorithm for Predicting Risk of Alzheimer's Disease.

Alzheimers Dement (N Y) 2016 Jan;2(1):30-44

Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Duke University Medical Center, Durham, North Carolina; Department of Neurology, Duke University Medical Center, Durham, North Carolina; Cabernet Pharmaceuticals, Durham, North Carolina; Zinfandel Pharmaceuticals, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.trci.2015.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817110PMC
January 2016

The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging.

J Parkinsons Dis Alzheimers Dis 2014 Nov;1(1)

Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA ; Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.13188/2376-922X.1000003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346331PMC
November 2014

The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes.

Eur Neuropsychopharmacol 2014 Sep 13;24(9):1492-9. Epub 2014 Jun 13.

The Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel; Department of Psychiatry, Mount Sinai School of Medicine, NY, USA.

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http://dx.doi.org/10.1016/j.euroneuro.2014.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753419PMC
September 2014

Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

PLoS One 2013 15;8(11):e80513. Epub 2013 Nov 15.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom ; Brain Research Imaging Centre, Division of Neuroimaging Sciences, University of Edinburgh, Edinburgh, United Kingdom ; Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom ; Medical Genetics Section, Centre for Genomics and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080513PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829876PMC
August 2014

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.

Neurobiol Aging 2014 Jun 8;35(6):1513.e25-33. Epub 2014 Jan 8.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK; Department of Psychology, University of Edinburgh, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969262PMC
June 2014

Mean diffusivity in the amygdala correlates with anxiety in pediatric TBI.

Brain Imaging Behav 2012 Mar;6(1):36-48

Department of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston, 7000 Fannin, ste 2411, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s11682-011-9140-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707402PMC
March 2012

Anxiety disorders in children and adolescents in the first six months after traumatic brain injury.

J Neuropsychiatry Clin Neurosci 2011 ;23(1):29-39

Department of Psychiatry at University of California, San Diego, Children's Hospital and Health Center, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1176/jnp.23.1.jnp29DOI Listing
December 2011

The importance of being connected.

J Alzheimers Dis 2011 ;24(2):247-51

Deane Drug Discovery Institute, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.3233/JAD-2010-101765DOI Listing
August 2011

Association of family stressful life-change events and health-related quality of life in fifth-grade children.

Arch Pediatr Adolesc Med 2011 Apr;165(4):354-9

Department of Pediatrics, Mattel Children's Hospital, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA.

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http://archpedi.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archpediatrics.2011.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582781PMC
April 2011

Genetic variation at a single locus and age of onset for Alzheimer's disease.

Alzheimers Dement 2010 Mar;6(2):125-31

Deane Drug Discovery Institute, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.jalz.2010.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874876PMC
March 2010

Genetic variation at a single locus and age of onset for Alzheimer's disease.

Alzheimers Dement 2010 Mar;6(2):125-31

Deane Drug Discovery Institute, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.jalz.2010.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874876PMC
March 2010

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons.

Proc Natl Acad Sci U S A 2008 Jan 22;105(4):1343-6. Epub 2008 Jan 22.

Gladstone Institute of Neurological Disease and Gladstone Institute of Cardiovascular Disease, The J. David Gladstone Institutes, 1650 Owens Street, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.0709906104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234140PMC
January 2008

Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates.

Am J Psychiatry 2007 Jun;164(6):916-21

Banner Alzheimer Institute, Banner Good Samaritan PET Center, 1111 E. McDowell Rd., Phoenix, AZ 85006, USA.

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http://dx.doi.org/10.1176/ajp.2007.164.6.916DOI Listing
June 2007

Rosiglitazone induces mitochondrial biogenesis in mouse brain.

J Alzheimers Dis 2007 Mar;11(1):45-51

Department of Quantitative Expression, Division of Genetics Research, GlaxoSmithKline, Research Triangle Park, NC 27278, USA.

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March 2007

Developing a psychopathology curriculum during child and adolescent psychiatry residency training: general principles and a problem-based approach.

Child Adolesc Psychiatr Clin N Am 2007 Jan;16(1):95-110, ix

Department of Psychiatry and Behavioral Sciences, University of Texas Medical School at Houston, 1300 Moursund Street, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.chc.2006.07.007DOI Listing
January 2007

APOE2 allele increased in tardive dyskinesia.

Mov Disord 2006 Apr;21(4):540-2

Department of Medicine (Neurology), Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1002/mds.20768DOI Listing
April 2006

Perspective on a pathogenesis and treatment of Alzheimer's disease.

Alzheimers Dement 2006 Apr;2(2):59-70

GlaxoSmithKline, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1016/j.jalz.2005.12.001DOI Listing
April 2006

Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery.

OMICS 2005 ;9(4):351-63

Genetics Research, GlaxoSmithKline Pharmaceuticals, 5 Moore Drive 5.5616, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1089/omi.2005.9.351DOI Listing
March 2006

Predictors of attention-deficit/hyperactivity disorder within 6 months after pediatric traumatic brain injury.

J Am Acad Child Adolesc Psychiatry 2005 Oct;44(10):1032-40

Department of Psychiatry, University of California, San Diego, USA.

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http://dx.doi.org/10.1097/01.chi.0000173293.05817.b1DOI Listing
October 2005

Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism.

Proc Natl Acad Sci U S A 2005 Jun 2;102(23):8299-302. Epub 2005 Jun 2.

Positron Emission Tomography Center, Banner Good Samaritan Medical Center, Phoenix, AZ 85006, USA.

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http://dx.doi.org/10.1073/pnas.0500579102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1149416PMC
June 2005

Predictors of personality change due to traumatic brain injury in children and adolescents in the first six months after injury.

J Am Acad Child Adolesc Psychiatry 2005 May;44(5):434-42

Department of Psychiatry, University of California, Children's Hospital and Health Center, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1097/01.chi.0000156280.66240.61DOI Listing
May 2005

A single-nucleotide polymorphism tagging set for human drug metabolism and transport.

Nat Genet 2005 Jan 19;37(1):84-9. Epub 2004 Dec 19.

Department of Biology (Galton Lab), University College London, The Darwin Building, Gower Street, London WC1E 6BT, UK.

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http://www.nature.com/articles/ng1488
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http://dx.doi.org/10.1038/ng1488DOI Listing
January 2005

Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.

Neurogenetics 2004 Dec 29;5(4):201-8. Epub 2004 Sep 29.

Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1007/s10048-004-0189-9DOI Listing
December 2004

Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis.

Neurogenetics 2004 Dec 2;5(4):209-13. Epub 2004 Oct 2.

Center for Human Genetics, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://link.springer.com/10.1007/s10048-004-0193-0
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http://dx.doi.org/10.1007/s10048-004-0193-0DOI Listing
December 2004

Periventricular leukomalacia is common after neonatal cardiac surgery.

J Thorac Cardiovasc Surg 2004 Mar;127(3):692-704

Division of Cardiothoracic Anesthesiology, The Cardiac Center, Children's Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2003.09.053DOI Listing
March 2004

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia.

Proc Natl Acad Sci U S A 2004 Jan 19;101(1):284-9. Epub 2003 Dec 19.

Positron Emission Tomography Center, Banner Good Samaritan Medical Center, Phoenix, AZ 85006, USA.

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http://dx.doi.org/10.1073/pnas.2635903100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC314177PMC
January 2004

Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.

Am J Hum Genet 2003 Nov 16;73(5):1041-51. Epub 2003 Oct 16.

Department of Medicine, Duke University Medical Center, and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University, Durham, NC 27710, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970761967
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180484PMC
http://dx.doi.org/10.1086/379083DOI Listing
November 2003

ApoE genotype-specific inhibition of apoptosis.

J Lipid Res 2003 Aug 16;44(8):1566-73. Epub 2003 May 16.

Division of Neurology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1194/jlr.M300097-JLR200DOI Listing
August 2003

The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.

Neurosci Lett 2003 Aug;347(3):143-6

Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Box 3445, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0304-3940(03)00670-0DOI Listing
August 2003

APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.

Neurobiol Aging 2002 Sep-Oct;23(5):777-85

Division of Neurology, Duke University Medical Center, Box 2900, Bryan Research Building, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0197-4580(02)00016-7DOI Listing
January 2003

Apolipoprotein E epsilon4 and risk of mortality in African American and white older community residents.

Gerontologist 2002 Jun;42(3):381-6

Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1093/geront/42.3.381DOI Listing
June 2002

Apolipoprotein E and intellectual achievement.

J Am Geriatr Soc 2002 Jan;50(1):49-54

Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA.

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http://dx.doi.org/10.1046/j.1532-5415.2002.50007.xDOI Listing
January 2002