Publications by authors named "Ann Massie"

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The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain.
Glia 2018 May 19;66(5):951-970. Epub 2018 Jan 19.
The Neurotransporter Group, Section of Anatomy, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, 0317, Norway.

Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.
Glia 2018 Apr 25. Epub 2018 Apr 25.
Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Brussels, 1090, Belgium.

Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.
World J Biol Psychiatry 2017 Sep 27:1-12. Epub 2017 Sep 27.
a Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information , Center for Neurosciences (C4N), Vrije Universiteit Brussel , Brussels , Belgium.

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.
Int J Mol Sci 2017 Mar 4;18(3). Epub 2017 Mar 4.
Research Group Experimental Pharmacology (EFAR/FASC), Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, 1090 Brussel, Belgium.

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed.
J Comp Neurol 2016 Apr 23;524(5):1015-32. Epub 2015 Oct 23.
Department of Pharmaceutical Biotechnology and Molecular Biology, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, 1090, Belgium.

In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions.
Physiol Behav 2016 Mar 18;156:199-207. Epub 2015 Dec 18.
Department of Pharmaceutical Chemistry and Drug Analysis, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address:

Alterations in the motor cortical and striatal glutamatergic system and D-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease.
Neurochem Int 2015 Sep 11;88:88-96. Epub 2015 Jul 11.
Department of Pharmaceutical Biotechnology and Molecular Biology, Center for Neurosciences, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium. Electronic address:

Validation of the 6 Hz refractory seizure mouse model for intracerebroventricularly administered compounds.
Epilepsy Res 2015 Sep 6;115:67-72. Epub 2015 Jun 6.
Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Center for Neurosciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address:

Neuropeptide FF receptors as novel targets for limbic seizure attenuation.
Neuropharmacology 2015 Aug 9;95:415-23. Epub 2015 May 9.
Center for Neurosciences, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address:

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision.
Prog Neuropsychopharmacol Biol Psychiatry 2015 Jun 23;59:49-58. Epub 2015 Jan 23.
Department of Pharmaceutical Chemistry and Drug Analysis, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address:

Lack of effect of Theiler's murine encephalomyelitis virus infection on system xc⁻.
Neurosci Lett 2015 Apr 18;593:124-8. Epub 2015 Mar 18.
Department of Pharmaceutical Biotechnology and Molecular Biology, Center for Neurosciences (C4N), Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address:

NMDA receptor antagonism potentiates the L-DOPA-induced extracellular dopamine release in the subthalamic nucleus of hemi-parkinson rats.
Neuropharmacology 2014 Oct 24;85:198-205. Epub 2014 May 24.
Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Center for Neuroscience, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium. Electronic address:


Assessment of the convulsant liability of antidepressants using zebrafish and mouse seizure models.
Epilepsy Behav 2011 Nov 1;22(3):450-60. Epub 2011 Oct 1.
Department of Pharmaceutical Chemistry and Drug Analysis, Center for Neuroscience, Vrije Universiteit Brussel, Brussels, Belgium.

Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
FASEB J 2011 Apr 29;25(4):1359-69. Epub 2010 Dec 29.
Department of Pharmaceutical Chemistry and Drug Analysis, Research Group Experimental Pharmacology, Vrije Universiteit Brussel, Brussels, Belgium.


Retinal lesions affect extracellular glutamate levels in sensory-deprived and remote non-deprived regions of cat area 17 as revealed by in vivo microdialysis.
Brain Res 2003 Feb;962(1-2):199-206
Laboratory of Neuroendocrinology and Immunological Biotechnology, Katholieke Universiteit Leuven, Naamsestraat 59, B-3000 Leuven, Belgium.

Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.
J Alzheimers Dis 2011 ;24(2):287-300
Research Group Experimental Pharmacology, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Centre of Pharmaceutical Research, Vrije Universiteit Brussel, Brussel, Belgium.

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein.
Front Behav Neurosci 2015 31;9:68. Epub 2015 Mar 31.
Department of Pharmaceutical Biotechnology and Molecular Biology, Center for Neurosciences, Vrije Universiteit Brussel Brussels, Belgium.

Zonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system x.
Exp Neurol 2017 04 24;290:15-28. Epub 2016 Dec 24.
Department of Pharmaceutical Biotechnology and Molecular Biology, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address:

Absence of system x on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.
J Neuroinflammation 2017 01 13;14(1). Epub 2017 Jan 13.
Center for Neurosciences (C4N), Department of Pharmaceutical Biotechnology and Molecular Biology, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.

Plastic changes at corticostriatal synapses predict improved motor function in a partial lesion model of Parkinson's disease.
Brain Res Bull 2017 04 20;130:257-267. Epub 2017 Feb 20.
Department of Pharmaceutical Biotechnology and Molecular Biology, Center for Neurosciences, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address:

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