Publications by authors named "Ann E Frazier"

33Publications

Assessment of mitochondrial respiratory chain enzymes in cells and tissues.

Methods Cell Biol 2020 14;155:121-156. Epub 2019 Dec 14.

Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; NHS Highly Specialised Mitochondrial Diagnostic Laboratory, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.mcb.2019.11.007DOI Listing
December 2019

Mitochondrial energy generation disorders: genes, mechanisms, and clues to pathology.

J Biol Chem 2019 04 12;294(14):5386-5395. Epub 2017 Dec 12.

From the Murdoch Children's Research Institute, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, and

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http://dx.doi.org/10.1074/jbc.R117.809194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462508PMC
April 2019

Reply: Genotype-phenotype correlation in ATAD3A deletions: not just of scientific relevance.

Brain 2017 11;140(11):e67

Murdoch Children's Research Institute, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, Melbourne VIC 3052, Australia.

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http://dx.doi.org/10.1093/brain/awx240DOI Listing
November 2017

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.

Mol Cell 2017 Aug 14;67(3):457-470.e5. Epub 2017 Jul 14.

Department of Biochemistry and Molecular Biology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.06.014DOI Listing
August 2017

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

Nature 2016 Oct 14;538(7623):123-126. Epub 2016 Sep 14.

Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, 3800, Melbourne, Australia.

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http://dx.doi.org/10.1038/nature19754DOI Listing
October 2016

Mitochondrial OXA Translocase Plays a Major Role in Biogenesis of Inner-Membrane Proteins.

Cell Metab 2016 May;23(5):901-8

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873616PMC
May 2016

Deletion of the Complex I Subunit NDUFS4 Adversely Modulates Cellular Differentiation.

Stem Cells Dev 2016 Feb 7;25(3):239-50. Epub 2016 Jan 7.

1 Centre for Genetic Diseases, Hudson Institute of Medical Research , Clayton, Australia .

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http://dx.doi.org/10.1089/scd.2015.0211DOI Listing
February 2016

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2.

Hum Mol Genet 2015 Oct 9;24(19):5404-15. Epub 2015 Jul 9.

Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Melbourne, Australia,

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http://dx.doi.org/10.1093/hmg/ddv265DOI Listing
October 2015

Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I.

Hum Mol Genet 2015 May 12;24(10):2952-65. Epub 2015 Feb 12.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne 3800, Australia,

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http://dx.doi.org/10.1093/hmg/ddv058DOI Listing
May 2015

Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.

Biosci Rep 2014 Nov 21;34(6):e00151. Epub 2014 Nov 21.

*Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1042/BSR20140151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240023PMC
November 2014

Functional characterization of Friedreich ataxia iPS-derived neuronal progenitors and their integration in the adult brain.

PLoS One 2014 7;9(7):e101718. Epub 2014 Jul 7.

Centre for Neural Engineering, Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Victoria, Australia; Department of Anatomy and Neuroscience, The University of Melbourne, Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101718PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084949PMC
February 2015

Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.

PLoS Genet 2013 26;9(12):e1004034. Epub 2013 Dec 26.

Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia ; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia ; Victorian Clinical Genetics Services, Royal Children's Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1004034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873243PMC
August 2014

Modelling biochemical features of mitochondrial neuropathology.

Biochim Biophys Acta 2014 Apr 23;1840(4):1380-92. Epub 2013 Oct 23.

The Murdoch Childrens Research Institute, The Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2013.10.017DOI Listing
April 2014

Biochemical analyses of the electron transport chain complexes by spectrophotometry.

Methods Mol Biol 2012 ;837:49-62

Murdoch Children's Research Institute, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-61779-504-6_4DOI Listing
April 2012

MiD49 and MiD51, new components of the mitochondrial fission machinery.

EMBO Rep 2011 Jun 21;12(6):565-73. Epub 2011 Apr 21.

La Trobe Institute for Molecular Science, La Trobe University, Plenty Road, Melbourne 3086, Victoria, Australia.

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http://dx.doi.org/10.1038/embor.2011.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128275PMC
June 2011

Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor.

J Biol Chem 2010 Nov 17;285(47):36876-83. Epub 2010 Sep 17.

La Trobe Institute for Molecular Science, La Trobe University, Melbourne 3086, Australia.

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http://dx.doi.org/10.1074/jbc.M110.159301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978617PMC
November 2010

Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks.

Biochim Biophys Acta 2010 May 15;1803(5):564-74. Epub 2010 Mar 15.

Department of Biochemistry, La Trobe University, 3086 Melbourne, Australia.

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http://dx.doi.org/10.1016/j.bbamcr.2010.03.006DOI Listing
May 2010

Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly.

EMBO J 2007 Oct 20;26(20):4347-58. Epub 2007 Sep 20.

Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, Universität Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7601862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034671PMC
October 2007

Mitochondrial protein-import machinery: correlating structure with function.

Trends Cell Biol 2007 Sep 6;17(9):456-64. Epub 2007 Sep 6.

Department of Biochemistry, La Trobe University, Melbourne 3086, Australia.

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http://dx.doi.org/10.1016/j.tcb.2007.07.010DOI Listing
September 2007

Mitochondrial morphology and distribution in mammalian cells.

Biol Chem 2006 Dec;387(12):1551-8

Department of Biochemistry, La Trobe University, 3086 Melbourne, Australia.

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https://www.degruyter.com/view/j/bchm.2006.387.issue-12/bc.2
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http://dx.doi.org/10.1515/BC.2006.193DOI Listing
December 2006

Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome.

Mol Biol Cell 2005 Nov 31;16(11):5202-14. Epub 2005 Aug 31.

Institut für Biochemie und Molekularbiologie, Universität Freiburg, D-79104 Freiburg, Germany.

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http://dx.doi.org/10.1091/mbc.e05-03-0256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266419PMC
November 2005

Pam16 has an essential role in the mitochondrial protein import motor.

Nat Struct Mol Biol 2004 Mar 15;11(3):226-33. Epub 2004 Feb 15.

Institut für Biochemie und Molekularbiologie, und Fakultät für Biologie, Universität Freiburg, D-79104 Freiburg, Germany.

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http://dx.doi.org/10.1038/nsmb735DOI Listing
March 2004

The protein import machinery of mitochondria.

J Biol Chem 2004 Apr 18;279(15):14473-6. Epub 2004 Feb 18.

Institut für Biochemie und Molekularbiologie, Universität Freiburg, D-79104 Freiburg, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.R400003200
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http://dx.doi.org/10.1074/jbc.R400003200DOI Listing
April 2004

Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space.

Mol Cell Biol 2003 Nov;23(21):7818-28

Institut für Biochemie und Molekularbiologie. Fakultät für Biologie, Universität Freiburg, D-79104 Freiburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC207575PMC
http://dx.doi.org/10.1128/mcb.23.21.7818-7828.2003DOI Listing
November 2003