Ann Daly

Ann Daly

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HLA associations with infliximab-induced liver injury.

Pharmacogenomics J 2020 Feb 6. Epub 2020 Feb 6.

Emerald Lake Safety, Newport Beach, CA, USA.

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http://dx.doi.org/10.1038/s41397-020-0159-0DOI Listing
February 2020

Investigation of Oxidative Stress-Related Candidate Genes as Risk Factors for Drug-Induced Liver Injury due to Co-Amoxiclav.

DNA Cell Biol 2020 Jan 6. Epub 2020 Jan 6.

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1089/dna.2019.4982DOI Listing
January 2020

Pharmacogenetics of Adverse Drug Reactions.

Adv Pharmacol 2018 ;83:155-190

Institute of Cellular Medicine, Newcastle University, Medical School, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.apha.2018.03.002DOI Listing
July 2019

Endocytosis and Lack of Cytotoxicity of Alkyl-Capped Silicon Quantum Dots Prepared from Porous Silicon.

Materials (Basel) 2019 May 25;12(10). Epub 2019 May 25.

Chemical Nanoscience Laboratory, School of Natural and Environmental Sciences, Newcastle University, Newcastle NE1 7RU, UK.

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http://dx.doi.org/10.3390/ma12101702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566257PMC
May 2019

Next-Generation Sequencing of Genes Reveals an Increased Frequency of Non-synonymous Variants Among Patients With NSAID-Induced Liver Injury.

Front Genet 2019 28;10:134. Epub 2019 Feb 28.

Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, UNEx, ARADyAL, Cáceres, Spain.

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http://dx.doi.org/10.3389/fgene.2019.00134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403122PMC
February 2019

HLA-A*33:03-Restricted Activation of Ticlopidine-Specific T-Cells from Human Donors.

Chem Res Toxicol 2018 10 13;31(10):1022-1024. Epub 2018 Sep 13.

MRC Center for Drug Safety Science, Department of Molecular and Clinical Pharmacology , University of Liverpool , Sherrington Building, Ashton Street , Liverpool , L69 3GE , England.

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http://pubs.acs.org/doi/10.1021/acs.chemrestox.8b00163
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http://dx.doi.org/10.1021/acs.chemrestox.8b00163DOI Listing
October 2018

Genetic and Clinical Factors Are Associated With Statin-Related Myotoxicity of Moderate Severity: A Case-Control Study.

Clin Pharmacol Ther 2018 07 9;104(1):178-187. Epub 2017 Nov 9.

Institute of Cellular Medicine, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1002/cpt.887DOI Listing
July 2018

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective.

Toxicol Res (Camb) 2018 May 6;7(3):347-357. Epub 2018 Mar 6.

Division of Computational and Systems Medicine , Department of Surgery and Cancer , Faculty of Medicine , Imperial College London , South Kensington , London SW7 2AZ , UK . Email:

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http://dx.doi.org/10.1039/c7tx00340dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062253PMC
May 2018

Pharmacogenetics: a general review on progress to date.

Authors:
Ann K Daly

Br Med Bull 2017 Dec;124(1):65-79

Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1093/bmb/ldx035DOI Listing
December 2017

Top ten research priorities for type 2 diabetes: results from the Diabetes UK-James Lind Alliance Priority Setting Partnership.

Lancet Diabetes Endocrinol 2017 12 30;5(12):935-936. Epub 2017 Oct 30.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S2213-8587(17)30324-8DOI Listing
December 2017

Pharmacogenomics of CYP2C9: Functional and Clinical Considerations.

J Pers Med 2017 Dec 28;8(1). Epub 2017 Dec 28.

Department of Clinical Pharmacology, Flinders University School of Medicine, Adelaide 5042, Australia.

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http://dx.doi.org/10.3390/jpm8010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872075PMC
December 2017

Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury?

Authors:
Ann K Daly

Pharm Res 2017 Aug 27;34(8):1564-1569. Epub 2016 Dec 27.

Institute of Cellular Medicine, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1007/s11095-016-2091-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498650PMC
August 2017

Defining drug response for stratified medicine.

Drug Discov Today 2017 01 3;22(1):173-179. Epub 2016 Nov 3.

Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool L69 3GL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2016.10.016DOI Listing
January 2017

Transcriptional regulation of PNPLA3 and its impact on susceptibility to nonalcoholic fatty liver Disease (NAFLD) in humans.

Aging (Albany NY) 2016 10;9(1):26-40

Division of Gastroenterology and Hepatology, Indiana Fatty Liver Disease Research Group, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.18632/aging.101067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310654PMC
October 2016

The Effect of the CYP1A1*2A Allele on Colorectal Cancer Susceptibility in a British Population.

Genet Test Mol Biomarkers 2016 Aug 31;20(8):475-7. Epub 2016 May 31.

2 Institute of Cellular Medicine, Newcastle University , Newcastle upon Tyne, United Kingdom .

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http://dx.doi.org/10.1089/gtmb.2016.0099DOI Listing
August 2016

Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol.

Clin Gastroenterol Hepatol 2016 May 18;14(5):762-8.e1. Epub 2015 Nov 18.

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.cgh.2015.11.005DOI Listing
May 2016

HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury.

Pharmacogenet Genomics 2016 May;26(5):218-24

Departments of aSystems Biology bBiomedical Informatics cThe Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York dUNC Eshelman School of Pharmacy, Chapel Hill, North Carolina eTarget Sciences, GSK, King of Prussia, Pennsylvania, USA fInstitute for Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Kiel gDrug Commission of the German Medical Association (DCGMA), Berlin, Germany hInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne iNational Institute for Health Research (NIHR), Nottingham Digestive Diseases Biomedical Research Unit, Nottingham University Hospital NHS Trust and University of Nottingham, Nottingham, UK jDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The National University Hospital of Iceland, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1097/FPC.0000000000000209DOI Listing
May 2016

Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases.

Authors:
Ann K Daly

Adv Pharmacol 2015 11;74:85-111. Epub 2015 May 11.

Institute of Cellular Medicine, Newcastle University, Medical School, Newcastle upon Tyne, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10543589150002
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http://dx.doi.org/10.1016/bs.apha.2015.03.001DOI Listing
April 2016

Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes.

Diabetes Care 2016 Jan 1;39(1):158-65. Epub 2015 Dec 1.

Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U.K. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U.K.

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http://dx.doi.org/10.2337/dc15-0750DOI Listing
January 2016

Genetics of Alcoholic Liver Disease.

Semin Liver Dis 2015 Nov 16;35(4):361-74. Epub 2015 Dec 16.

Liver Research Group, Institute of Cellular Medicine, The Medical School, Newcastle University, Framlington Place, Newcastle-upon-Tyne, United Kingdom.

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http://dx.doi.org/10.1055/s-0035-1567832DOI Listing
November 2015

TM6SF2 as a genetic risk factor for fibrosis.

Hepatology 2015 Oct 19;62(4):1321. Epub 2015 Jun 19.

Institute of Cellular Medicine, Newcastle University, Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/hep.27656DOI Listing
October 2015

Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury.

Hepatology 2015 Sep 23;62(3):887-99. Epub 2015 Jul 23.

MRC Center for Drug Safety Science, Department of Molecular and Clinical Pharmacology, The University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1002/hep.27912DOI Listing
September 2015

Promiscuous T-cell responses to drugs and drug-haptens.

J Allergy Clin Immunol 2015 Aug 22;136(2):474-6.e8. Epub 2015 Apr 22.

Department of Clinical and Molecular Pharmacology, Medical Research Council Centre for Drug Safety Science, The University of Liverpool, Liverpool, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.02.036DOI Listing
August 2015

Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants.

Thromb Res 2015 Jul 25;136(1):69-75. Epub 2015 Apr 25.

The Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.04.026DOI Listing
July 2015

TM6SF2: catch-22 in the fight against nonalcoholic fatty liver disease and cardiovascular disease?

Gastroenterology 2015 Apr 29;148(4):679-84. Epub 2015 Jan 29.

University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.01.038DOI Listing
April 2015

Oral anticoagulation: a critique of recent advances and controversies.

Trends Pharmacol Sci 2015 Mar 17;36(3):153-63. Epub 2015 Feb 17.

Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.tips.2015.01.003DOI Listing
March 2015

N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group.

Eur J Clin Pharmacol 2014 Sep 3;70(9):1079-86. Epub 2014 Jun 3.

Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1007/s00228-014-1703-0DOI Listing
September 2014

Relevance of CYP2E1 to non-alcoholic fatty liver disease.

Authors:
Ann K Daly

Subcell Biochem 2013 ;67:165-75

Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, NE2 4HH, Newcastle upon Tyne, UK,

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http://dx.doi.org/10.1007/978-94-007-5881-0_5DOI Listing
August 2014

Pharmacogenomics of adverse drug reactions.

Authors:
Ann K Daly

Genome Med 2013 29;5(1). Epub 2013 Jan 29.

Institute of Cellular Medicine, Newcastle University, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1186/gm409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707028PMC
June 2014

Point of care testing for improving risk- benefit ratio of aspirin and warfarin.

Mol Cytogenet 2014 21;7(Suppl 1 Proceedings of the International Conference on Human):I54. Epub 2014 Jan 21.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1186/1755-8166-7-S1-I54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044298PMC
June 2014

Genetic basis of drug-induced liver injury: present and future.

Semin Liver Dis 2014 May 31;34(2):123-33. Epub 2014 May 31.

National Institute for Health Research Nottingham Digestive Diseases Biomedical research Unit, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.1055/s-0034-1375954DOI Listing
May 2014

Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon.

Br J Clin Pharmacol 2014 Apr;77(4):626-41

Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht.

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http://dx.doi.org/10.1111/bcp.12220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971980PMC
April 2014

Opportunities and limitations: the value of pharmacogenetics in clinical practice.

Br J Clin Pharmacol 2014 Apr;77(4):583-6

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/bcp.12354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971974PMC
April 2014

Human leukocyte antigen (HLA) pharmacogenomic tests: potential and pitfalls.

Authors:
Ann K Daly

Curr Drug Metab 2014 Feb;15(2):196-201

Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.2174/138920021502140327180733DOI Listing
February 2014

A randomized trial of genotype-guided dosing of warfarin.

N Engl J Med 2013 Dec 19;369(24):2294-303. Epub 2013 Nov 19.

From the University of Liverpool (M.P., G.B., A.L.J., C.H.T., J.E.Z., P.R.W.) and Royal Liverpool and Broadgreen University Hospital National Health Service (NHS) Trust (M.P., C.H.T.), Liverpool, Whiston Hospital, Prescot (T.N.), and Newcastle upon Tyne NHS Trust (P.K.) and Newcastle University (J.B.L., A.K.D., P.A., F.K.), Newcastle upon Tyne - all in the United Kingdom; Uppsala University, Department of Medical Sciences (N.E., C.C., H.K., M.W.), Uppsala Clinical Research Center (N.E.) and Uppsala University Hospital (C.C., B.W., M.W.), Uppsala, and Enköping Hospital, Enköping (C.S.) - all in Sweden; and Utrecht University, Utrecht, the Netherlands (A.H.M.Z.).

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http://dx.doi.org/10.1056/NEJMoa1311386DOI Listing
December 2013

Efavirenz induced acute liver failure requiring liver transplantation in a slow drug metaboliser.

J Clin Virol 2013 Sep 12;58(1):331-3. Epub 2013 Jun 12.

Liver Unit, University Hospitals Birmingham, Edgbaston, Birmingham B15 2WB, United Kingdom.

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http://dx.doi.org/10.1016/j.jcv.2013.05.003DOI Listing
September 2013

Optimal dosing of warfarin and other coumarin anticoagulants: the role of genetic polymorphisms.

Authors:
Ann K Daly

Arch Toxicol 2013 Mar 2;87(3):407-20. Epub 2013 Feb 2.

Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1007/s00204-013-1013-9DOI Listing
March 2013

Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population.

Clin Chim Acta 2013 Feb 21;416:11-9. Epub 2012 Nov 21.

Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.

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http://dx.doi.org/10.1016/j.cca.2012.11.011DOI Listing
February 2013

Genetic polymorphisms affecting drug metabolism: recent advances and clinical aspects.

Authors:
Ann K Daly

Adv Pharmacol 2012 ;63:137-67

Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/B978-0-12-398339-8.00004-5DOI Listing
November 2012

Using genome-wide association studies to identify genes important in serious adverse drug reactions.

Authors:
Ann K Daly

Annu Rev Pharmacol Toxicol 2012 1;52:21-35. Epub 2011 Aug 1.

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.

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http://www.annualreviews.org/doi/10.1146/annurev-pharmtox-01
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http://dx.doi.org/10.1146/annurev-pharmtox-010611-134743DOI Listing
May 2012

Genetic association studies in drug-induced liver injury.

Drug Metab Rev 2012 Feb 14;44(1):116-26. Epub 2011 Sep 14.

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.3109/03602532.2011.605790DOI Listing
February 2012

The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver.

J Hepatol 2011 Dec 21;55(6):1409-14. Epub 2011 Jul 21.

Department of Internal Medicine, Università degli Studi Milano, UO Medicina Interna 1B, Ospedale Maggiore Ca' Granda Fondazione Policlinico IRCCS, Milan, Italy.

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http://dx.doi.org/10.1016/j.jhep.2011.03.035DOI Listing
December 2011

Cyclooxygenase-2 polymorphisms and pancreatic cancer susceptibility.

Pancreas 2011 Nov;40(8):1289-94

Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.

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http://dx.doi.org/10.1097/MPA.0b013e31821fcc3bDOI Listing
November 2011

Genetic modifiers of non-alcoholic fatty liver disease progression.

Biochim Biophys Acta 2011 Nov 5;1812(11):1557-66. Epub 2011 Aug 5.

Liver Research Group, Instiutte of Cellular Medicine, Teh Medical School, Newcastle University, Framlington Place, Newcaltle-upon-Type, NE2 4HHK, UK.

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http://dx.doi.org/10.1016/j.bbadis.2011.07.017DOI Listing
November 2011

Genetics of alcoholic and nonalcoholic fatty liver disease.

Semin Liver Dis 2011 May 2;31(2):128-46. Epub 2011 May 2.

Liver Research Group, Institute of Cellular Medicine, The Medical School, Newcastle University, Framlington Place, Newcastle-upon-Tyne, United Kingdom.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0031-1276643
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http://dx.doi.org/10.1055/s-0031-1276643DOI Listing
May 2011

Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease.

Expert Rev Gastroenterol Hepatol 2011 Apr;5(2):253-63

Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1586/egh.11.18DOI Listing
April 2011

Genotypes and phenotypes of CYP3A in Bangladeshi population.

Clin Chim Acta 2011 Mar 27;412(7-8):531-6. Epub 2010 Nov 27.

Department of Clinical Pharmacy & Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.

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http://dx.doi.org/10.1016/j.cca.2010.11.031DOI Listing
March 2011

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury.

J Hepatol 2010 Dec 1;53(6):1049-53. Epub 2010 Aug 1.

Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1016/j.jhep.2010.05.033DOI Listing
December 2010

Relevance of nonsynonymous CYP2C8 polymorphisms to 13-cis retinoic acid and paclitaxel hydroxylation.

Drug Metab Dispos 2010 Aug 26;38(8):1261-6. Epub 2010 Apr 26.

Northern Institute for Cancer Research, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1124/dmd.109.030866DOI Listing
August 2010

Pharmacogenetics and human genetic polymorphisms.

Authors:
Ann K Daly

Biochem J 2010 Aug;429(3):435-49

Institute of Cellular Medicine, Newcastle University Medical School, UK.

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http://dx.doi.org/10.1042/BJ20100522DOI Listing
August 2010

Preempting and preventing drug-induced liver injury.

Nat Genet 2010 Aug;42(8):650-1

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http://dx.doi.org/10.1038/ng0810-650DOI Listing
August 2010

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

Drug Metab Dispos 2010 Jul 22;38(7):1211-7. Epub 2010 Mar 22.

Northern Institute for Cancer Research, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1124/dmd.109.031625DOI Listing
July 2010

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.

Ann Rheum Dis 2010 Jul 6;69(7):1315-20. Epub 2010 May 6.

Musculoskeletal Research Group, Institute of Cellular Medicine, University of Newcastle, 4th Floor Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1136/ard.2009.117309DOI Listing
July 2010

Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype.

Br J Nutr 2010 Jun 19;103(11):1585-93. Epub 2010 Jan 19.

Institute for Cell and Molecular Biosciences, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1017/S0007114509993540DOI Listing
June 2010

A role for the pregnane X receptor in flucloxacillin-induced liver injury.

Hepatology 2010 May;51(5):1656-64

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/hep.23549DOI Listing
May 2010

Drug-induced liver injury: past, present and future.

Authors:
Ann K Daly

Pharmacogenomics 2010 May;11(5):607-11

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.2217/pgs.10.24DOI Listing
May 2010

Polymorphisms in the tropomyosin TPM1 short isoform promoter alter gene expression and are associated with increased risk of metabolic syndrome.

Am J Hypertens 2010 Apr 14;23(4):399-404. Epub 2010 Jan 14.

Centre for Endocrine and Diabetes Sciences, School of Medicine, University of Cardiff, Cardiff, UK.

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http://dx.doi.org/10.1038/ajh.2009.278DOI Listing
April 2010

Genome-wide association studies in pharmacogenomics.

Authors:
Ann K Daly

Nat Rev Genet 2010 Apr;11(4):241-6

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1038/nrg2751DOI Listing
April 2010

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

Hepatology 2010 Apr;51(4):1209-17

Department of Internal Medicine, Università degli Studi Milano, UO Medicina Interna 1B, Fondazione Ospedale Policlinico MaRE Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.

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http://dx.doi.org/10.1002/hep.23622DOI Listing
April 2010

Patatin-like phospholipase domain containing 3: a case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease.

Hepatology 2010 Apr;51(4):1463-5

Centenary Institute and Drug Health Services, Royal Prince Alfred Hospital, University of SydneyCamperdown, NSW, Australia.

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http://dx.doi.org/10.1002/hep.23606DOI Listing
April 2010

Genetic association studies in drug-induced liver injury.

Semin Liver Dis 2009 Nov 13;29(4):400-11. Epub 2009 Oct 13.

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0029-1240009
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http://dx.doi.org/10.1055/s-0029-1240009DOI Listing
November 2009

Conference scene: initiatives on future biobanking in pharmacogenomics.

Pharmacogenomics 2009 Jul;10(7):1135-8

Division of Pharmacoepidemiology & Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, The Netherlands.

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http://dx.doi.org/10.2217/pgs.09.73DOI Listing
July 2009

Pharmacogenomics of anticoagulants: steps toward personal dosage.

Authors:
Ann K Daly

Genome Med 2009 Jan 21;1(1):10. Epub 2009 Jan 21.

Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1186/gm10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651584PMC
January 2009