Ann Chen Wu

Ann Chen Wu

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Social Media and the Allergist: Evidence Supports Increasing Our Engagement.

J Allergy Clin Immunol Pract 2018 Jan - Feb;6(1):313-314

Division of Allergy and Immunology, Nationwide Children's Hospital, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio.

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http://dx.doi.org/10.1016/j.jaip.2017.09.007DOI Listing
September 2019

Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions.

Metabolites 2019 Sep 7;9(9). Epub 2019 Sep 7.

PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/metabo9090179DOI Listing
September 2019

Reply to Mahler: Peak Inspiratory Flow Rate: An Emerging Biomarker in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2019 Jun;199(12):1579

2 University of Pennsylvania Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201902-0432LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580675PMC
June 2019

Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

J Allergy Clin Immunol 2019 Apr 20;143(4):1633-1635. Epub 2018 Dec 20.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183277
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http://dx.doi.org/10.1016/j.jaci.2018.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451881PMC
April 2019

Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.

Pediatr Pulmonol 2019 Feb 25;54(2):158-164. Epub 2018 Dec 25.

Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1002/ppul.24219DOI Listing
February 2019

Is Telemedicine as Effective as Usual Care?

J Allergy Clin Immunol Pract 2019 Jan;7(1):217-218

Center for Health Care Research in Pediatrics (CHeRP), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.09.002DOI Listing
January 2019

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

J Allergy Clin Immunol 2018 11 9;142(5):1469-1478.e2. Epub 2018 Jan 9.

Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037620PMC
November 2018

Systems biology and in vitro validation identifies family with sequence similarity 129 member A (FAM129A) as an asthma steroid response modulator.

J Allergy Clin Immunol 2018 11 2;142(5):1479-1488.e12. Epub 2018 Mar 2.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.11.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111005PMC
November 2018

The Implementation Process for Pharmacogenomic Testing for Cancer-Targeted Therapies.

J Pers Med 2018 Oct 1;8(4). Epub 2018 Oct 1.

PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, 401 Park Drive, Suite 401, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/jpm8040032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313431PMC
October 2018

Increasing trends of anaphylaxis-related events: an analysis of anaphylaxis using nationwide data in Taiwan, 2001-2013.

World Allergy Organ J 2018 10;11(1):23. Epub 2018 Oct 10.

6Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli 350 Taiwan.

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https://waojournal.biomedcentral.com/articles/10.1186/s40413
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http://dx.doi.org/10.1186/s40413-018-0202-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178262PMC
October 2018

The impact of FDA regulatory activities on incident dispensing of LABA-containing medication: 2005-2011.

J Asthma 2018 08 13;55(8):907-914. Epub 2017 Oct 13.

h Office of Pharmacovigilance and Epidemiology, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research , U.S. Food and Drug Administration , Silver Spring , MD , USA.

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http://dx.doi.org/10.1080/02770903.2017.1378355DOI Listing
August 2018

The Promise of Improving Asthma Control Using Mobile Health.

Authors:
Ann Chen Wu

J Allergy Clin Immunol Pract 2016 Jul-Aug;4(4):738-9

Department of Population Medicine, Center for Healthcare Research in Pediatrics, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Mass; Division of General Pediatrics, Department of Pediatrics, Children's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2016.04.003DOI Listing
July 2018

Quantifying the Polygenic Contribution to Cutaneous Squamous Cell Carcinoma Risk.

J Invest Dermatol 2018 07 13;138(7):1507-1510. Epub 2018 Feb 13.

Precision Medicine Translational Research Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019610PMC
July 2018

Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer.

J Pers Med 2018 May 16;8(2). Epub 2018 May 16.

Precision Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401 East, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/jpm8020019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023380PMC
May 2018

Racial disparities in family-provider interactions for pediatric asthma care.

J Asthma 2018 04 14;55(4):424-429. Epub 2017 Jul 14.

g Center for Healthcare Research in Pediatrics, Department of Population Medicine , Harvard Pilgrim Health Care Institute and Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/02770903.2017.1337790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340291PMC
April 2018

Impact of Copayment Changes on Children's Albuterol Inhaler Use and Costs after the Clean Air Act Chlorofluorocarbon Ban.

Health Serv Res 2018 02 20;53(1):156-174. Epub 2016 Nov 20.

Center for Healthcare Research in Pediatrics, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA.

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http://dx.doi.org/10.1111/1475-6773.12615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785321PMC
February 2018

Increased Dose and Duration of Statin Use Is Associated with Decreased Asthma-Related Emergency Department Visits and Hospitalizations.

J Allergy Clin Immunol Pract 2018 Sep - Oct;6(5):1588-1595.e1. Epub 2018 Feb 6.

Allergy and Clinical Immunology Research (ACIR) Centre, National Cheng Kung University, Tainan, Taiwan; Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Ill. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.12.017DOI Listing
February 2018

Asthma: Overdiagnosed, Underdiagnosed, and Ineffectively Treated.

J Allergy Clin Immunol Pract 2018 May - Jun;6(3):801-802

Center for Healthcare Research in Pediatrics (CHeRP), Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Mass; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.02.023DOI Listing
February 2018

Access to Guideline-Recommended Pharmacogenomic Tests for Cancer Treatments: Experience of Providers and Patients.

J Pers Med 2017 Nov 15;7(4). Epub 2017 Nov 15.

Precision Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, 401 Park Drive, Suite 401, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/jpm7040017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748629PMC
November 2017

Coordinated Asthma Program Improves Asthma Outcomes in High-Risk Children.

Clin Pediatr (Phila) 2017 Sep 24;56(10):934-941. Epub 2017 Apr 24.

1 Boston Children's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1177/0009922817705186DOI Listing
September 2017

Asthma Metabolomics and the Potential for Integrative Omics in Research and the Clinic.

Chest 2017 Feb 21;151(2):262-277. Epub 2016 Oct 21.

Channing Division of Network Medicine, Brigham Women's Hospital and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2016.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310123PMC
February 2017

Changing patterns of asthma medication use related to US Food and Drug Administration long-acting β2-agonist regulation from 2005-2011.

J Allergy Clin Immunol 2016 Mar 22;137(3):710-7. Epub 2015 Dec 22.

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.09.057DOI Listing
March 2016

Mobile health applications for asthma.

J Allergy Clin Immunol Pract 2015 May-Jun;3(3):446-8.e1-16. Epub 2015 Feb 25.

Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pa.

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http://dx.doi.org/10.1016/j.jaip.2014.12.011DOI Listing
February 2016

Pharmacogenomic test that predicts response to inhaled corticosteroids in adults with asthma likely to be cost-saving.

Pharmacogenomics 2015 16;16(6):591-600. Epub 2015 Apr 16.

Center for Child Health Care Studies, Department of Population Medicine, Harvard Medical School & Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, Boston, MA 02215-5301, USA.

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http://dx.doi.org/10.2217/pgs.15.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545673PMC
February 2016

CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids.

Immun Inflamm Dis 2015 Dec 14;3(4):350-9. Epub 2015 Jul 14.

Channing Division of Network Medicine, Department of MedicineBrigham and Women's Hospital and Harvard Medical SchoolBostonMassachusetts02115; Center for Child Health Care Studies, Department of Population MedicineHarvard Pilgrim Health Care Institute and Harvard Medical SchoolBostonMassachusetts02115.

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http://dx.doi.org/10.1002/iid3.73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693729PMC
December 2015

Pharmacogenomic test that predicts response to β-agonists in adults with asthma is cost effective.

Per Med 2015 Nov;12(6):574-584

Division of Pulmonary & Critical Care Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.2217/pme.15.23DOI Listing
November 2015

The metabolomics of asthma control: a promising link between genetics and disease.

Immun Inflamm Dis 2015 Sep 7;3(3):224-38. Epub 2015 May 7.

Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/iid3.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578522PMC
September 2015

Measuring the corticosteroid responsiveness endophenotype in asthmatic patients.

J Allergy Clin Immunol 2015 Aug 5;136(2):274-81.e8. Epub 2015 May 5.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749150043
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http://dx.doi.org/10.1016/j.jaci.2015.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530065PMC
August 2015

Measuring the corticosteroid responsiveness endophenotype in asthmatic patients.

J Allergy Clin Immunol 2015 Aug 5;136(2):274-81.e8. Epub 2015 May 5.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749150043
Publisher Site
http://dx.doi.org/10.1016/j.jaci.2015.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530065PMC
August 2015

Use of leukotriene receptor antagonists are associated with a similar risk of asthma exacerbations as inhaled corticosteroids.

J Allergy Clin Immunol Pract 2014 Sep-Oct;2(5):607-13. Epub 2014 Jul 25.

Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Mass; Division of General Pediatrics, Department of Pediatrics, Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass; Division of Research, Kaiser Permanente Northern California, Oakland, Calif.

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http://dx.doi.org/10.1016/j.jaip.2014.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557573PMC
May 2015

Primary adherence to controller medications for asthma is poor.

Ann Am Thorac Soc 2015 Feb;12(2):161-6

1 Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School.

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http://dx.doi.org/10.1513/AnnalsATS.201410-459OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342835PMC
February 2015

Financial barriers to care among low-income children with asthma: health care reform implications.

JAMA Pediatr 2014 Jul;168(7):649-56

Center for Child Health Care Studies, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamapediatrics.2014.79DOI Listing
July 2014

Reply: the beneficial effect of statins on asthma exacerbations: another point of view.

Am J Respir Crit Care Med 2014 Jul;190(1):119

1 Sainte-Justine University Hospital Center Montréal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.201404-0657LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226032PMC
July 2014

Statin use in asthmatics on inhaled corticosteroids is associated with decreased risk of emergency department visits.

Curr Med Res Opin 2014 Apr 18;30(4):685-93. Epub 2013 Dec 18.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, MA , USA.

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http://dx.doi.org/10.1185/03007995.2013.865599DOI Listing
April 2014

Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.

J Allergy Clin Immunol 2014 Mar 23;133(3):723-8.e3. Epub 2013 Nov 23.

Harvard Medical School, Boston, Mass; Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Mass; Center for Genomic Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2013.09.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943570PMC
March 2014

Statin exposure is associated with decreased asthma-related emergency department visits and oral corticosteroid use.

Am J Respir Crit Care Med 2013 Nov;188(9):1076-82

1 Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201306-1017OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863744PMC
November 2013

Modeling asthma exacerbations through lung function in children.

J Allergy Clin Immunol 2012 Nov 27;130(5):1065-70. Epub 2012 Sep 27.

Department of Population Medicine, Center for Child Health Care Studies, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jaci.2012.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683131PMC
November 2012

Effect of vitamin D and inhaled corticosteroid treatment on lung function in children.

Am J Respir Crit Care Med 2012 Sep 12;186(6):508-13. Epub 2012 Jul 12.

Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA 02215-5301, USA.

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http://dx.doi.org/10.1164/rccm.201202-0351OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480528PMC
September 2012

Predictors of symptoms are different from predictors of severe exacerbations from asthma in children.

Chest 2011 Jul 3;140(1):100-107. Epub 2011 Feb 3.

Harvard Medical School, Department of Medicine, Brigham and Women's Hospital, Boston, MA; Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1378/chest.10-2794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130529PMC
July 2011

Acceptance of Asthma Pharmacogenetic Study by Children and Adults.

J Pharmacogenomics Pharmacoproteomics 2011 Apr;2(103)

Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA ; Department of Pediatrics, Children's Hospital, Boston, MA ; Kaiser Permanente South East, Atlanta, GA.

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http://dx.doi.org/10.4172/2153-0645.1000103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614400PMC
April 2011

Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations.

Am J Respir Crit Care Med 2010 Oct 10;182(7):884-9. Epub 2010 Jun 10.

Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1164/rccm.201003-0322OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970860PMC
October 2010

Development of a Pharmacogenetic Predictive Test in asthma: proof of concept.

Pharmacogenet Genomics 2010 Feb;20(2):86-93

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, 6th Floor, Boston, MA 02215-5301, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32833428d0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654515PMC
February 2010

Outcomes after periodic use of inhaled corticosteroids in children.

J Asthma 2009 Jun;46(5):517-22

Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Medical School, 133 Brookline Avenue, 6th Floor, Boston, MA 02215, USA.

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http://dx.doi.org/10.1080/02770900802468517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004094PMC
June 2009

Repeatability of response to asthma medications.

J Allergy Clin Immunol 2009 Feb 6;123(2):385-90. Epub 2008 Dec 6.

Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Mass, USA.

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http://dx.doi.org/10.1016/j.jaci.2008.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980870PMC
February 2009

INSIG2 is Associated with Lower Gain in Weight-for-Length Between Birth and Age 6 Months.

Clin Med Pediatr 2009 ;3:33-37

Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Massachusetts, U.S.A.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846639PMC
January 2009

Postpartum mothers' attitudes, knowledge, and trust regarding vaccination.

Matern Child Health J 2008 Nov 7;12(6):766-73. Epub 2007 Nov 7.

Department of Ambulatory Care and Prevention, Harvard Medical School, and Children's Hospital, 133 Brookline Avenue, 6th Floor, Boston, MA 02215-5301, USA.

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http://dx.doi.org/10.1007/s10995-007-0302-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344281PMC
November 2008

Racial/Ethnic variation in parent perceptions of asthma.

Ambul Pediatr 2008 Mar-Apr;8(2):89-97

Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA 02215-5301, USA.

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http://dx.doi.org/10.1016/j.ambp.2007.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614412PMC
May 2008

The interpreter as cultural educator of residents: improving communication for Latino parents.

Arch Pediatr Adolesc Med 2006 Nov;160(11):1145-50

Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1001/archpedi.160.11.1145DOI Listing
November 2006

Screening for iron deficiency.

Pediatr Rev 2002 May;23(5):171-8

Hunnewell Ground Children's Hospital. Associate Professor of Pediatrics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1542/pir.23-5-171DOI Listing
May 2002