Anke Hinney

Anke Hinney

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Anke Hinney

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Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study.

Nutrients 2019 May 16;11(5). Epub 2019 May 16.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.

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http://dx.doi.org/10.3390/nu11051085DOI Listing
May 2019

Melanocortin-4 Receptor and Lipocalin 2 Gene Variants in Spanish Children with Abdominal Obesity: Effects on BMI-SDS After a Lifestyle Intervention.

Nutrients 2019 Apr 26;11(5). Epub 2019 Apr 26.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 174, D-45147, Essen,Germany.

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http://dx.doi.org/10.3390/nu11050960DOI Listing
April 2019

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.

Am J Psychiatry 2019 Mar;176(3):217-227

The Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston (Yu, Illmann, Osiecki, Smoller, Pauls, Neale, Scharf); the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Mass. (Yu, Neale, Scharf); the Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles (Sul, Huang, Zelaya, Ophoff, Freimer, Coppola); the Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (Sul, Huang, Zelaya, Freimer, Coppola); the Department of Molecular Biology and Genetics, Democritus University of Thrace, Xanthi, Greece (Tsetsos); the Department of Biological Sciences, Purdue University, West Lafayette, Ind. (Tsetsos, Paschou); deCODE Genetics/Amgen, Reykjavik, Iceland (Nawaz, H. Stefansson, K. Stefansson); the Bioinformatics Interdepartmental Program, University of California, Los Angeles (Huang, Zelaya); the Department of Psychiatry, University of California, San Francisco (Darrow); the Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco (Hirschtritt, Willsey); the Department of Psychiatry, Massachusetts General Hospital, Boston (Greenberg, Roffman, Buckner); the Clinic of Psychiatry, Social Psychiatry, and Psychotherapy, Hannover Medical School, Hannover, Germany (Muller-Vahl); the Institute of Human Genetics, Hannover Medical School, Hannover, Germany (Stuhrmann); McGill University Health Center, University of Montreal, McGill University Health Centre, Montreal (Dion); the Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal (Rouleau); the Department of Psychiatry and Psychotherapy, Medical University Vienna, Vienna (Aschauer, Stamenkovic); Biopsychosocial Corporation, Vienna (Aschauer, Schlögelhofer); University Health Network, Youthdale Treatment Centres, and University of Toronto, Toronto (Sandor); the Krembil Research Institute, University Health Network, Hospital for Sick Children, and University of Toronto, Toronto (Barr); Johns Hopkins University School of Medicine, Baltimore (Grados, Singer); the Institute of Human Genetics, University Hospital Bonn, University of Bonn Medical School, Bonn, Germany (Nöthen); the Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany (Hebebrand, Hinney); the Yale Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (King, Fernandez); the Institute of Medical Chemistry, Molecular Biology, and Pathobiochemistry, Semmelweis University, Budapest, Hungary (Barta); Vadaskert Child and Adolescent Psychiatric Hospital, Budapest, Hungary (Tarnok, Nagy); the Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen, Essen, Germany (Depienne); Sorbonne Universités, UPMC Université Paris 06, UMR S 1127, CNRS UMR 7225, ICM, Paris (Depienne, Worbe, Hartmann); French Reference Centre for Gilles de la Tourette Syndrome, Groupe Hospitalier Pitié-Salpêtrière, Paris (Worbe, Hartmann); Assistance Publique-Hôpitaux de Paris, Department of Neurology, Groupe Hospitalier Pitié-Salpêtrière, Paris (Worbe, Hartmann); Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York (Budman); Child Neuropsychiatry, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy (Rizzo); the Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (Lyon); the Department of Psychiatry, University of Utah, Salt Lake City (McMahon); Children's Mercy Hospital, Kansas City, Mo. (Batterson); the Department of Psychiatry, University Medical Center Groningen and Rijksuniversity Groningen, and Drenthe Mental Health Center, Groningen, the Netherlands (Cath); the Department of Neurology, Fixel Center for Neurological Diseases, McKnight Brain Institute, University of Florida, Gainesville (Malaty, Okun); Pennsylvania State University College of Medicine, Hershey (Berlin); Marquette University and University of Wisconsin-Milwaukee, Milwaukee (Woods); Tripler Army Medical Center and University of Hawaii John A. Burns School of Medicine, Honolulu (Lee); Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston (Jankovic); the Division of Psychiatry, Department of Neuropsychiatry, University College London (Robertson); the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati (Gilbert); Children's Hospital of Philadelphia, Philadelphia (Brown); the Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami (Coffey); the Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (Dietrich, Hoekstra); University of Iowa Carver College of Medicine, Iowa City (Kuperman); the Department of Pediatrics, University of Washington, Seattle (Zinner); the Department of Pediatrics, Landspitalinn University Hospital, Reykjavik, Iceland (Luðvigsson, Thorarensen); the Faculty of Medicine, University of Iceland, Reykjavík, Iceland (Sæmundsen, Stefansson); the State Diagnostic and Counselling Centre, Kópavogur, Iceland (Sæmundsen); the Department of Genetics and the Department of Medicine, Albert Einstein College of Medicine, Bronx, New York (Atzmon, Barzilai); the Department of Human Biology, Haifa University, Haifa, Israel (Atzmon); the Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany (Wagner); the Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany (Moessner); SUNY Downstate Medical Center Brooklyn, New York (C.M. Pato, M.T. Pato, Knowles); the Athinoula A. Martinos Center for Biomedical Research, Department of Radiology, Massachusetts General Hospital, Charlestown (Roffman, Buckner); the Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston (Smoller); the Center for Brain Science and Department of Psychology, Harvard University, Cambridge, Mass. (Buckner); the Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco (Willsey); the Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway (Tischfield, Heiman); the Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, VU University Amsterdam, Amsterdam (Posthuma); the Division of Genetic Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tenn. (Cox, Davis); the Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston (Neale); the Department of Psychiatry, Genetics Institute, University of Florida, Gainesville (Mathews); and the Department of Neurology, Brigham and Women's Hospital, and the Department of Neurology, Massachusetts General Hospital, Boston (Scharf).

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http://dx.doi.org/10.1176/appi.ajp.2018.18070857DOI Listing
March 2019

The association of serum leptin levels with food addiction is moderated by weight status in adolescent psychiatric inpatients.

Eur Eat Disord Rev 2018 11 4;26(6):618-628. Epub 2018 Sep 4.

Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/erv.2637DOI Listing
November 2018

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.

Am J Med Genet B Neuropsychiatr Genet 2018 Nov 25. Epub 2018 Nov 25.

Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.

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http://doi.wiley.com/10.1002/ajmg.b.32695
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http://dx.doi.org/10.1002/ajmg.b.32695DOI Listing
November 2018

Relevance of polymorphisms in MC4R and BDNF in short normal stature.

BMC Pediatr 2018 08 22;18(1):278. Epub 2018 Aug 22.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1186/s12887-018-1245-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106737PMC
August 2018

Waist-hip ratio related genetic loci are associated with risk of impaired fasting glucose in Chinese children: a case control study.

Nutr Metab (Lond) 2018 3;15:34. Epub 2018 May 3.

1Department of Maternal and Child Health, School of Public Health, Peking University, No.38 Xueyuan Road, Haidian District, Beijing, 100191 China.

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http://dx.doi.org/10.1186/s12986-018-0270-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934898PMC
May 2018

High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation.

World J Biol Psychiatry 2018 04 1;19(3):187-199. Epub 2016 Jul 1.

c Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy , University Hospital Essen, University of Duisburg-Essen , Essen , Germany.

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http://dx.doi.org/10.1080/15622975.2016.1190033DOI Listing
April 2018

The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.

Obes Facts 2018 10;11(2):93-108. Epub 2018 Apr 10.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1159/000486962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981666PMC
April 2018

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients - a randomized controlled trial: study protocol.

BMC Psychiatry 2018 03 1;18(1):57. Epub 2018 Mar 1.

Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Wickenburgstr. 21, D-45147, Essen, Germany.

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http://dx.doi.org/10.1186/s12888-018-1637-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831612PMC
March 2018

Estimated prevalence of potentially damaging variants in the leptin gene.

Mol Cell Pediatr 2017 Nov 3;4(1):10. Epub 2017 Nov 3.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Eythstr. 24, D-89075, Ulm, Germany.

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http://dx.doi.org/10.1186/s40348-017-0074-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670095PMC
November 2017

Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.

Am J Psychiatry 2017 09 12;174(9):850-858. Epub 2017 May 12.

From the UNC Center of Excellence for Eating Disorders, Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm; the Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston; the Social, Genetic, and Developmental Psychiatry Research Centre and Biomedical Research Centre for Mental Health at King's College London and South London and Maudsley NHS Trust; and the Broad Institute of MIT and Harvard, Cambridge, Mass.

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http://dx.doi.org/10.1176/appi.ajp.2017.16121402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581217PMC
September 2017

Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach.

Am J Med Genet B Neuropsychiatr Genet 2016 09 22;171(6):815-26. Epub 2016 Mar 22.

Division of Bioinformatics & Computational Biology, Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon.

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http://dx.doi.org/10.1002/ajmg.b.32446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983253PMC
September 2016

Decreased melanocortin-4 receptor function conferred by an infrequent variant at the human melanocortin receptor accessory protein 2 gene.

Obesity (Silver Spring) 2016 09 30;24(9):1976-82. Epub 2016 Jul 30.

Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/oby.21576DOI Listing
September 2016

Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses.

PLoS One 2014 15;9(9):e107665. Epub 2014 Sep 15.

Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164653PMC
December 2015

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.

Hum Mol Genet 2015 Jun 17;24(12):3582-94. Epub 2015 Mar 17.

Department of Clinical Epidemiology and Biostatistics, Divisions of Genetics and Endocrinology, Children's Hospital, Boston, MA 02115, USA, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA,

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http://hmg.oxfordjournals.org/content/early/2015/04/02/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddv097
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http://dx.doi.org/10.1093/hmg/ddv097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498155PMC
June 2015

FTO gene: association to weight regain after lifestyle intervention in overweight children.

Horm Res Paediatr 2014 7;81(6):391-6. Epub 2014 May 7.

Department of Pediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten/Herdecke, Datteln, Germany.

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http://dx.doi.org/10.1159/000358328DOI Listing
March 2015

[Perspectives of genetic research in eating disorders using the example of anorexia nervosa].

Psychother Psychosom Med Psychol 2015 Jan 16;65(1):8-10. Epub 2015 Jan 16.

Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, Universitätsklinikum Essen.

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http://dx.doi.org/10.1055/s-0034-1394405DOI Listing
January 2015

Genes and the hypothalamic control of metabolism in humans.

Best Pract Res Clin Endocrinol Metab 2014 Oct 26;28(5):635-47. Epub 2014 Apr 26.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Universitätsklinikum Essen, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2014.04.007DOI Listing
October 2014

A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes.

PLoS One 2013 31;8(12):e83426. Epub 2013 Dec 31.

Molecular Nutritional Medicine, Else Kröner-Fresenius Center & Research Center for Nutrition and Food Sciences, Technische Universität München, Freising-Weihenstephan, Germany.

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https://mediatum.ub.tum.de/doc/1210018/1210018.pdf
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http://dx.plos.org/10.1371/journal.pone.0083426
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083426PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877035PMC
August 2014

Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis.

Prog Mol Biol Transl Sci 2013 ;114:147-91

Department of Child and Adolescent Psychiatry, Universitätsklinikum, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1016/B978-0-12-386933-3.00005-4DOI Listing
June 2014

Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.

Am J Med Genet B Neuropsychiatr Genet 2014 Jun 1;165B(4):283-93. Epub 2014 May 1.

Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, Universitätsklinikum Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/ajmg.b.32234DOI Listing
June 2014

Genetics of eating disorders.

Curr Psychiatry Rep 2013 Dec;15(12):423

Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg-Essen, Virchowstrasse 171, 45147, Essen, Germany,

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http://dx.doi.org/10.1007/s11920-013-0423-yDOI Listing
December 2013

Association analyses for dopamine receptor gene polymorphisms and weight status in a longitudinal analysis in obese children before and after lifestyle intervention.

BMC Pediatr 2013 Nov 27;13:197. Epub 2013 Nov 27.

Department of Pediatrics, University of Washington, Seattle Children's Research Institute, 1900 Ninth Ave, Seattle, WA 98101, USA.

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http://dx.doi.org/10.1186/1471-2431-13-197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219494PMC
November 2013

Successful treatment with atomoxetine of an adolescent boy with attention deficit/hyperactivity disorder, extreme obesity, and reduced melanocortin 4 receptor function.

Obes Facts 2013 6;6(1):109-15. Epub 2013 Mar 6.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Human Medicine, Philipps-University Marburg, Germany.

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http://dx.doi.org/10.1159/000348792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644743PMC
September 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

Authors:
Sonja I Berndt Stefan Gustafsson Reedik Mägi Andrea Ganna Eleanor Wheeler Mary F Feitosa Anne E Justice Keri L Monda Damien C Croteau-Chonka Felix R Day Tõnu Esko Tove Fall Teresa Ferreira Davide Gentilini Anne U Jackson Jian'an Luan Joshua C Randall Sailaja Vedantam Cristen J Willer Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Yi-Juan Hu Sang Hong Lee Liming Liang Dan-Yu Lin Josine L Min Benjamin M Neale Gudmar Thorleifsson Jian Yang Eva Albrecht Najaf Amin Jennifer L Bragg-Gresham Gemma Cadby Martin den Heijer Niina Eklund Krista Fischer Anuj Goel Jouke-Jan Hottenga Jennifer E Huffman Ivonne Jarick Åsa Johansson Toby Johnson Stavroula Kanoni Marcus E Kleber Inke R König Kati Kristiansson Zoltán Kutalik Claudia Lamina Cecile Lecoeur Guo Li Massimo Mangino Wendy L McArdle Carolina Medina-Gomez Martina Müller-Nurasyid Julius S Ngwa Ilja M Nolte Lavinia Paternoster Sonali Pechlivanis Markus Perola Marjolein J Peters Michael Preuss Lynda M Rose Jianxin Shi Dmitry Shungin Albert Vernon Smith Rona J Strawbridge Ida Surakka Alexander Teumer Mieke D Trip Jonathan Tyrer Jana V Van Vliet-Ostaptchouk Liesbeth Vandenput Lindsay L Waite Jing Hua Zhao Devin Absher Folkert W Asselbergs Mustafa Atalay Antony P Attwood Anthony J Balmforth Hanneke Basart John Beilby Lori L Bonnycastle Paolo Brambilla Marcel Bruinenberg Harry Campbell Daniel I Chasman Peter S Chines Francis S Collins John M Connell William O Cookson Ulf de Faire Femmie de Vegt Mariano Dei Maria Dimitriou Sarah Edkins Karol Estrada David M Evans Martin Farrall Marco M Ferrario Jean Ferrières Lude Franke Francesca Frau Pablo V Gejman Harald Grallert Henrik Grönberg Vilmundur Gudnason Alistair S Hall Per Hall Anna-Liisa Hartikainen Caroline Hayward Nancy L Heard-Costa Andrew C Heath Johannes Hebebrand Georg Homuth Frank B Hu Sarah E Hunt Elina Hyppönen Carlos Iribarren Kevin B Jacobs John-Olov Jansson Antti Jula Mika Kähönen Sekar Kathiresan Frank Kee Kay-Tee Khaw Mika Kivimäki Wolfgang Koenig Aldi T Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Jaana H Laitinen Timo A Lakka Claudia Langenberg Lenore J Launer Lars Lind Jaana Lindström Jianjun Liu Antonio Liuzzi Marja-Liisa Lokki Mattias Lorentzon Pamela A Madden Patrik K Magnusson Paolo Manunta Diana Marek Winfried März Irene Mateo Leach Barbara McKnight Sarah E Medland Evelin Mihailov Lili Milani Grant W Montgomery Vincent Mooser Thomas W Mühleisen Patricia B Munroe Arthur W Musk Narisu Narisu Gerjan Navis George Nicholson Ellen A Nohr Ken K Ong Ben A Oostra Colin N A Palmer Aarno Palotie John F Peden Nancy Pedersen Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Inga Prokopenko Carolin Pütter Aparna Radhakrishnan Olli Raitakari Augusto Rendon Fernando Rivadeneira Igor Rudan Timo E Saaristo Jennifer G Sambrook Alan R Sanders Serena Sanna Jouko Saramies Sabine Schipf Stefan Schreiber Heribert Schunkert So-Youn Shin Stefano Signorini Juha Sinisalo Boris Skrobek Nicole Soranzo Alena Stančáková Klaus Stark Jonathan C Stephens Kathleen Stirrups Ronald P Stolk Michael Stumvoll Amy J Swift Eirini V Theodoraki Barbara Thorand David-Alexandre Tregouet Elena Tremoli Melanie M Van der Klauw Joyce B J van Meurs Sita H Vermeulen Jorma Viikari Jarmo Virtamo Veronique Vitart Gérard Waeber Zhaoming Wang Elisabeth Widén Sarah H Wild Gonneke Willemsen Bernhard R Winkelmann Jacqueline C M Witteman Bruce H R Wolffenbuttel Andrew Wong Alan F Wright M Carola Zillikens Philippe Amouyel Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock L Adrienne Cupples Daniele Cusi George V Dedoussis Jeanette Erdmann Johan G Eriksson Paul W Franks Philippe Froguel Christian Gieger Ulf Gyllensten Anders Hamsten Tamara B Harris Christian Hengstenberg Andrew A Hicks Aroon Hingorani Anke Hinney Albert Hofman Kees G Hovingh Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Karl-Heinz Jöckel Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Diana Kuh Markku Laakso Terho Lehtimäki Douglas F Levinson Nicholas G Martin Andres Metspalu Andrew D Morris Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Willem H Ouwehand Lyle J Palmer Brenda Penninx Chris Power Michael A Province Bruce M Psaty Lu Qi Rainer Rauramaa Paul M Ridker Samuli Ripatti Veikko Salomaa Nilesh J Samani Harold Snieder Thorkild I A Sørensen Timothy D Spector Kari Stefansson Anke Tönjes Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Peter Vollenweider Henri Wallaschofski Nicholas J Wareham Hugh Watkins H-Erich Wichmann James F Wilson Goncalo R Abecasis Themistocles L Assimes Inês Barroso Michael Boehnke Ingrid B Borecki Panos Deloukas Caroline S Fox Timothy Frayling Leif C Groop Talin Haritunian Iris M Heid David Hunter Robert C Kaplan Fredrik Karpe Miriam F Moffatt Karen L Mohlke Jeffrey R O'Connell Yudi Pawitan Eric E Schadt David Schlessinger Valgerdur Steinthorsdottir David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Peter M Visscher Anna Maria Di Blasio Joel N Hirschhorn Cecilia M Lindgren Andrew P Morris David Meyre André Scherag Mark I McCarthy Elizabeth K Speliotes Kari E North Ruth J F Loos Erik Ingelsson

Nat Genet 2013 May 7;45(5):501-12. Epub 2013 Apr 7.

US Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973018PMC
May 2013

Molecular genetic aspects of weight regulation.

Dtsch Arztebl Int 2013 May 10;110(19):338-44. Epub 2013 May 10.

Department of Child and Adolescent Psychiatry, LVR-Klinikum Essen, University of Duisburg-Essen, Wickenburgstrasse 21, Essen, Germany.

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http://dx.doi.org/10.3238/arztebl.2013.0338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673040PMC
May 2013

Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through.

Obesity (Silver Spring) 2012 May 7;20(5):1074-81. Epub 2011 Jul 7.

Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1038/oby.2011.202DOI Listing
May 2012

A genome-wide association meta-analysis identifies new childhood obesity loci.

Nat Genet 2012 May;44(5):526-31

Center for Applied Genomics, Abramson Research Center, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.2247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370100PMC
May 2012

SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents.

Obesity (Silver Spring) 2012 Feb 17;20(2):466-70. Epub 2011 Nov 17.

Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1038/oby.2011.339DOI Listing
February 2012

Where in the genome are significant single nucleotide polymorphisms from genome-wide association studies located?

OMICS 2011 Jul-Aug;15(7-8):507-12. Epub 2011 Jun 23.

Institute of Animal Sciences, Humboldt-Universtät zu Berlin, Germany.

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http://dx.doi.org/10.1089/omi.2010.0154DOI Listing
November 2011

Association of the rs10830963 polymorphism in MTNR1B with fasting glucose levels in Chinese children and adolescents.

Obes Facts 2011 6;4(3):197-203. Epub 2011 Jun 6.

Division of Maternal and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.

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https://www.karger.com/Article/FullText/329306
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November 2011

Genetic findings in anorexia and bulimia nervosa.

Prog Mol Biol Transl Sci 2010 ;94:241-70

Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg-Essen, Germany.

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July 2011

Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder.

Eur J Pharmacol 2011 Jun 3;660(1):165-70. Epub 2011 Jan 3.

Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Virchowstr. 174, D - 45147 Essen, Germany.

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June 2011

Relationship between MTNR1B (melatonin receptor 1B gene) polymorphism rs10830963 and glucose levels in overweight children and adolescents.

Pediatr Diabetes 2011 Jun 3;12(4 Pt 2):435-41. Epub 2011 Mar 3.

Department of Pediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten/Herdecke, Germany.

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http://doi.wiley.com/10.1111/j.1399-5448.2010.00738.x
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June 2011

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis.

Hum Mol Genet 2011 Feb 2;20(4):840-52. Epub 2010 Dec 2.

Institute of Medical Biometry and Epidemiology, Philipps-University of Marburg, Bunsenstraße 3, D-35037 Marburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024044PMC
February 2011

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:
Elizabeth K Speliotes Cristen J Willer Sonja I Berndt Keri L Monda Gudmar Thorleifsson Anne U Jackson Hana Lango Allen Cecilia M Lindgren Jian'an Luan Reedik Mägi Joshua C Randall Sailaja Vedantam Thomas W Winkler Lu Qi Tsegaselassie Workalemahu Iris M Heid Valgerdur Steinthorsdottir Heather M Stringham Michael N Weedon Eleanor Wheeler Andrew R Wood Teresa Ferreira Robert J Weyant Ayellet V Segrè Karol Estrada Liming Liang James Nemesh Ju-Hyun Park Stefan Gustafsson Tuomas O Kilpeläinen Jian Yang Nabila Bouatia-Naji Tõnu Esko Mary F Feitosa Zoltán Kutalik Massimo Mangino Soumya Raychaudhuri Andre Scherag Albert Vernon Smith Ryan Welch Jing Hua Zhao Katja K Aben Devin M Absher Najaf Amin Anna L Dixon Eva Fisher Nicole L Glazer Michael E Goddard Nancy L Heard-Costa Volker Hoesel Jouke-Jan Hottenga Asa Johansson Toby Johnson Shamika Ketkar Claudia Lamina Shengxu Li Miriam F Moffatt Richard H Myers Narisu Narisu John R B Perry Marjolein J Peters Michael Preuss Samuli Ripatti Fernando Rivadeneira Camilla Sandholt Laura J Scott Nicholas J Timpson Jonathan P Tyrer Sophie van Wingerden Richard M Watanabe Charles C White Fredrik Wiklund Christina Barlassina Daniel I Chasman Matthew N Cooper John-Olov Jansson Robert W Lawrence Niina Pellikka Inga Prokopenko Jianxin Shi Elisabeth Thiering Helene Alavere Maria T S Alibrandi Peter Almgren Alice M Arnold Thor Aspelund Larry D Atwood Beverley Balkau Anthony J Balmforth Amanda J Bennett Yoav Ben-Shlomo Richard N Bergman Sven Bergmann Heike Biebermann Alexandra I F Blakemore Tanja Boes Lori L Bonnycastle Stefan R Bornstein Morris J Brown Thomas A Buchanan Fabio Busonero Harry Campbell Francesco P Cappuccio Christine Cavalcanti-Proença Yii-Der Ida Chen Chih-Mei Chen Peter S Chines Robert Clarke Lachlan Coin John Connell Ian N M Day Martin den Heijer Jubao Duan Shah Ebrahim Paul Elliott Roberto Elosua Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Maurizio F Facheris Stephan B Felix Pamela Fischer-Posovszky Aaron R Folsom Nele Friedrich Nelson B Freimer Mao Fu Stefan Gaget Pablo V Gejman Eco J C Geus Christian Gieger Anette P Gjesing Anuj Goel Philippe Goyette Harald Grallert Jürgen Grässler Danielle M Greenawalt Christopher J Groves Vilmundur Gudnason Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Alistair S Hall Aki S Havulinna Caroline Hayward Andrew C Heath Christian Hengstenberg Andrew A Hicks Anke Hinney Albert Hofman Georg Homuth Jennie Hui Wilmar Igl Carlos Iribarren Bo Isomaa Kevin B Jacobs Ivonne Jarick Elizabeth Jewell Ulrich John Torben Jørgensen Pekka Jousilahti Antti Jula Marika Kaakinen Eero Kajantie Lee M Kaplan Sekar Kathiresan Johannes Kettunen Leena Kinnunen Joshua W Knowles Ivana Kolcic Inke R König Seppo Koskinen Peter Kovacs Johanna Kuusisto Peter Kraft Kirsti Kvaløy Jaana Laitinen Olivier Lantieri Chiara Lanzani Lenore J Launer Cecile Lecoeur Terho Lehtimäki Guillaume Lettre Jianjun Liu Marja-Liisa Lokki Mattias Lorentzon Robert N Luben Barbara Ludwig Paolo Manunta Diana Marek Michel Marre Nicholas G Martin Wendy L McArdle Anne McCarthy Barbara McKnight Thomas Meitinger Olle Melander David Meyre Kristian Midthjell Grant W Montgomery Mario A Morken Andrew P Morris Rosanda Mulic Julius S Ngwa Mari Nelis Matt J Neville Dale R Nyholt Christopher J O'Donnell Stephen O'Rahilly Ken K Ong Ben Oostra Guillaume Paré Alex N Parker Markus Perola Irene Pichler Kirsi H Pietiläinen Carl G P Platou Ozren Polasek Anneli Pouta Suzanne Rafelt Olli Raitakari Nigel W Rayner Martin Ridderstråle Winfried Rief Aimo Ruokonen Neil R Robertson Peter Rzehak Veikko Salomaa Alan R Sanders Manjinder S Sandhu Serena Sanna Jouko Saramies Markku J Savolainen Susann Scherag Sabine Schipf Stefan Schreiber Heribert Schunkert Kaisa Silander Juha Sinisalo David S Siscovick Jan H Smit Nicole Soranzo Ulla Sovio Jonathan Stephens Ida Surakka Amy J Swift Mari-Liis Tammesoo Jean-Claude Tardif Maris Teder-Laving Tanya M Teslovich John R Thompson Brian Thomson Anke Tönjes Tiinamaija Tuomi Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Jorma Viikari Sophie Visvikis-Siest Veronique Vitart Carla I G Vogel Benjamin F Voight Lindsay L Waite Henri Wallaschofski G Bragi Walters Elisabeth Widen Susanna Wiegand Sarah H Wild Gonneke Willemsen Daniel R Witte Jacqueline C Witteman Jianfeng Xu Qunyuan Zhang Lina Zgaga Andreas Ziegler Paavo Zitting John P Beilby I Sadaf Farooqi Johannes Hebebrand Heikki V Huikuri Alan L James Mika Kähönen Douglas F Levinson Fabio Macciardi Markku S Nieminen Claes Ohlsson Lyle J Palmer Paul M Ridker Michael Stumvoll Jacques S Beckmann Heiner Boeing Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock Francis S Collins L Adrienne Cupples George Davey Smith Jeanette Erdmann Philippe Froguel Henrik Grönberg Ulf Gyllensten Per Hall Torben Hansen Tamara B Harris Andrew T Hattersley Richard B Hayes Joachim Heinrich Frank B Hu Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Jaakko Kaprio Fredrik Karpe Kay-Tee Khaw Lambertus A Kiemeney Heiko Krude Markku Laakso Debbie A Lawlor Andres Metspalu Patricia B Munroe Willem H Ouwehand Oluf Pedersen Brenda W Penninx Annette Peters Peter P Pramstaller Thomas Quertermous Thomas Reinehr Aila Rissanen Igor Rudan Nilesh J Samani Peter E H Schwarz Alan R Shuldiner Timothy D Spector Jaakko Tuomilehto Manuela Uda André Uitterlinden Timo T Valle Martin Wabitsch Gérard Waeber Nicholas J Wareham Hugh Watkins James F Wilson Alan F Wright M Carola Zillikens Nilanjan Chatterjee Steven A McCarroll Shaun Purcell Eric E Schadt Peter M Visscher Themistocles L Assimes Ingrid B Borecki Panos Deloukas Caroline S Fox Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Karen L Mohlke Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Cornelia M van Duijn H-Erich Wichmann Timothy M Frayling Unnur Thorsteinsdottir Gonçalo R Abecasis Inês Barroso Michael Boehnke Kari Stefansson Kari E North Mark I McCarthy Joel N Hirschhorn Erik Ingelsson Ruth J F Loos

Nat Genet 2010 Nov 10;42(11):937-48. Epub 2010 Oct 10.

Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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November 2010

Chipping away the 'missing heritability': GIANT steps forward in the molecular elucidation of obesity - but still lots to go.

Obes Facts 2010 Oct 15;3(5):294-303. Epub 2010 Oct 15.

Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg-Essen, Essen, Germany.

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October 2010

Estrogen receptor 1 gene (ESR1) is associated with restrictive anorexia nervosa.

Neuropsychopharmacology 2010 Jul 7;35(8):1818-25. Epub 2010 Apr 7.

INSERM U894-Team 1, Center of Psychiatry and Neurosciences, University Paris Descartes, 2ter rue d'Alésia, Paris, France.

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July 2010

Sympathetic function in human carriers of melanocortin-4 receptor gene mutations.

J Clin Endocrinol Metab 2010 Apr 10;95(4):1998-2002. Epub 2010 Feb 10.

First Department of Medicine, University Hospital of Schleswig-Holstein, Campus Luebeck, Ratzeburger Allee 160, D-23538 Luebeck, Germany.

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April 2010

Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals.

Obesity (Silver Spring) 2010 Mar 20;18(3):573-9. Epub 2009 Aug 20.

Division of Maternal and Child Health, School of Public Health, Peking University Health Science Center, Beijing, China.

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March 2010

Eating disorders: the current status of molecular genetic research.

Eur Child Adolesc Psychiatry 2010 Mar 24;19(3):211-26. Epub 2009 Dec 24.

Department of Child and Adolescent Psychiatry and Psychotherapy, LVR-Klinikum Essen, University of Duisburg-Essen, Virchowstrasse 174, Essen, Germany.

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http://dx.doi.org/10.1007/s00787-009-0085-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839487PMC
March 2010

From monogenic to polygenic obesity: recent advances.

Eur Child Adolesc Psychiatry 2010 Mar 3;19(3):297-310. Epub 2010 Feb 3.

Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg-Essen, Virchowstrasse 174, Essen, Germany.

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http://dx.doi.org/10.1007/s00787-010-0096-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839509PMC
March 2010

Child and adolescent psychiatric genetics.

Eur Child Adolesc Psychiatry 2010 Mar 6;19(3):259-79. Epub 2010 Feb 6.

Department of Child and Adolescent Psychiatry, LVR-Klinikum Essen, University of Duisburg-Essen, Virchowstrasse 174, Essen, Germany.

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http://dx.doi.org/10.1007/s00787-010-0091-yDOI Listing
March 2010

Changes of peripheral alpha-melanocyte-stimulating hormone in childhood obesity.

Metabolism 2010 Feb 18;59(2):186-94. Epub 2009 Sep 18.

Division of Endocrinology, Seattle Children's Hospital Research Institute, Seattle, WA 98101, USA.

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February 2010

Familiality and molecular genetics of attention networks in ADHD.

Am J Med Genet B Neuropsychiatr Genet 2010 Jan;153B(1):148-58

Child Neuropsychology Section, Department of Child and Adolescent Psychiatry of RTWH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/ajmg.b.30967DOI Listing
January 2010

Three at one swoop!

Obes Facts 2009 16;2(1):3-8. Epub 2009 Feb 16.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444680PMC
January 2010

Causal attributions of obese men and women in genetic testing: implications of genetic/biological attributions.

Psychol Health 2009 Sep;24(7):749-61

Department of Psychology, Division of Clinical Psychology and Psychological Therapy, Philipps University of Marburg, Marburg, Germany.

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September 2009

[Obesity and overweight].

Z Kinder Jugendpsychiatr Psychother 2009 Jul;37(4):237-44

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July 2009

Serotonin transporter gene polymorphism (5-HTTLPR), environmental conditions, and developing negative emotionality and fear in early childhood.

J Neural Transm (Vienna) 2009 Apr 10;116(4):503-12. Epub 2009 Jan 10.

Department of Medical Psychology, Faculty of Medicine, University of Giessen, Friedrichstrasse 36, 35392, Giessen, Germany.

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http://dx.doi.org/10.1007/s00702-008-0171-zDOI Listing
April 2009

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.

Obesity (Silver Spring) 2009 Apr 22;17(4):745-54. Epub 2009 Jan 22.

Department of Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/oby.2008.589DOI Listing
April 2009

Lifestyle intervention in obese children with variations in the melanocortin 4 receptor gene.

Obesity (Silver Spring) 2009 Feb 6;17(2):382-9. Epub 2008 Nov 6.

Department of Pediatric Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten/Herdecke, Datteln, Germany.

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February 2009

Increased constraints on MC4R during primate and human evolution.

Hum Genet 2009 Jan 15;124(6):633-47. Epub 2008 Nov 15.

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00439-008-0591-8DOI Listing
January 2009

Environmental and genetic risk factors in obesity.

Child Adolesc Psychiatr Clin N Am 2009 Jan;18(1):83-94

Department of Child and Adolescent Psychiatry, Rheinische Kliniken Essen, University of Duisburg-Essen, Virchowstr, 174, D-45147 Essen, Germany.

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January 2009

Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system.

J Neural Transm (Vienna) 2008 Jul 30;115(7):1071-8. Epub 2008 Apr 30.

Department of Child and Adolescent Psychiatry and Psychotherapy, University of Würzburg, Füchsleinstr. 15, 97080 Würzburg, Germany.

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July 2008

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Authors:
Ruth J F Loos Cecilia M Lindgren Shengxu Li Eleanor Wheeler Jing Hua Zhao Inga Prokopenko Michael Inouye Rachel M Freathy Antony P Attwood Jacques S Beckmann Sonja I Berndt Kevin B Jacobs Stephen J Chanock Richard B Hayes Sven Bergmann Amanda J Bennett Sheila A Bingham Murielle Bochud Morris Brown Stéphane Cauchi John M Connell Cyrus Cooper George Davey Smith Ian Day Christian Dina Subhajyoti De Emmanouil T Dermitzakis Alex S F Doney Katherine S Elliott Paul Elliott David M Evans I Sadaf Farooqi Philippe Froguel Jilur Ghori Christopher J Groves Rhian Gwilliam David Hadley Alistair S Hall Andrew T Hattersley Johannes Hebebrand Iris M Heid Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Blanca Herrera Anke Hinney Sarah E Hunt Marjo-Riitta Jarvelin Toby Johnson Jennifer D M Jolley Fredrik Karpe Andrew Keniry Kay-Tee Khaw Robert N Luben Massimo Mangino Jonathan Marchini Wendy L McArdle Ralph McGinnis David Meyre Patricia B Munroe Andrew D Morris Andrew R Ness Matthew J Neville Alexandra C Nica Ken K Ong Stephen O'Rahilly Katharine R Owen Colin N A Palmer Konstantinos Papadakis Simon Potter Anneli Pouta Lu Qi Joshua C Randall Nigel W Rayner Susan M Ring Manjinder S Sandhu André Scherag Matthew A Sims Kijoung Song Nicole Soranzo Elizabeth K Speliotes Holly E Syddall Sarah A Teichmann Nicholas J Timpson Jonathan H Tobias Manuela Uda Carla I Ganz Vogel Chris Wallace Dawn M Waterworth Michael N Weedon Cristen J Willer Wraight Xin Yuan Eleftheria Zeggini Joel N Hirschhorn David P Strachan Willem H Ouwehand Mark J Caulfield Nilesh J Samani Timothy M Frayling Peter Vollenweider Gerard Waeber Vincent Mooser Panos Deloukas Mark I McCarthy Nicholas J Wareham Inês Barroso Kevin B Jacobs Stephen J Chanock Richard B Hayes Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Peter Kraft Susan E Hankinson David J Hunter Frank B Hu Helen N Lyon Benjamin F Voight Martin Ridderstrale Leif Groop Paul Scheet Serena Sanna Goncalo R Abecasis Giuseppe Albai Ramaiah Nagaraja David Schlessinger Anne U Jackson Jaakko Tuomilehto Francis S Collins Michael Boehnke Karen L Mohlke

Nat Genet 2008 Jun 4;40(6):768-75. Epub 2008 May 4.

MRC Epidemiology Unit, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669167PMC
June 2008

Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia.

BMC Cancer 2008 Mar 31;8:85. Epub 2008 Mar 31.

Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359760PMC
March 2008