Anita Pathil

Anita Pathil

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Anita Pathil

Anita Pathil

Publications by authors named "Anita Pathil"

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Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury.

PLoS One 2018 24;13(5):e0197836. Epub 2018 May 24.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197836PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967712PMC
December 2018

Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization.

Int J Mol Sci 2018 Oct 20;19(10). Epub 2018 Oct 20.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

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http://www.mdpi.com/1422-0067/19/10/3254
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http://dx.doi.org/10.3390/ijms19103254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214129PMC
October 2018

Could inherited predisposition drive non-obese fatty liver disease? Results from German tertiary referral centers.

J Hum Genet 2018 May 26;63(5):621-626. Epub 2018 Feb 26.

Department of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1038/s10038-018-0420-4DOI Listing
May 2018

Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors.

Nutrients 2018 May 21;10(5). Epub 2018 May 21.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/nu10050649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986528PMC
May 2018

Ursodeoxycholyl lysophosphatidylethanolamide negatively regulates TLR-mediated lipopolysaccharide response in human THP-1-derived macrophages.

Eur J Pharmacol 2018 Apr 20;825:63-74. Epub 2018 Feb 20.

Department of Internal Medicine IV, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00142999183010
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http://dx.doi.org/10.1016/j.ejphar.2018.02.030DOI Listing
April 2018

Predictors of functional benefit of hepatitis C therapy in a 'real-life' cohort.

World J Gastroenterol 2018 Feb;24(7):852-861

Department of Internal Medicine IV, University Hospital Heidelberg, Heidelberg 69120, Germany.

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http://dx.doi.org/10.3748/wjg.v24.i7.852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807943PMC
February 2018

The overall fatty acid absorption controlled by basolateral chylomicron excretion under regulation of p-JNK1.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Sep 6;1862(9):917-928. Epub 2017 Jun 6.

Department of Internal Medicine, University Hospital of Heidelberg, INF 410, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.bbalip.2017.05.013DOI Listing
September 2017

Ursodeoxycholyl Lysophosphatidylethanolamide Protects Against CD95/FAS-Induced Fulminant Hepatitis.

Shock 2017 08;48(2):251-259

*Department of Internal Medicine IV, University of Heidelberg Hospital, Heidelberg, Germany †School of Allied Health Sciences and Public Health, Walailak University, Nakhon Si Thammarat, Thailand.

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http://dx.doi.org/10.1097/SHK.0000000000000831DOI Listing
August 2017

Ledipasvir plus sofosbuvir fixed-dose combination for 6 weeks in patients with acute hepatitis C virus genotype 1 monoinfection (HepNet Acute HCV IV): an open-label, single-arm, phase 2 study.

Lancet Infect Dis 2017 02 28;17(2):215-222. Epub 2016 Oct 28.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; HepNet Study-House, German Liver Foundation, Hannover, Germany; German Centre for Infection Research (DZIF), partner site Hannover-Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(16)30408-XDOI Listing
February 2017

Cervical esophagotomy for foreign body extraction - Case report and comprehensive review of the literature.

Ann Med Surg (Lond) 2016 May 7;7:87-91. Epub 2016 Apr 7.

Department of General, Visceral and Transplant Surgery, University Hospital Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1016/j.amsu.2016.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840399PMC
May 2016

Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD.

Eur J Clin Invest 2015 Sep 14;45(9):925-31. Epub 2015 Jul 14.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/eci.12486DOI Listing
September 2015

Ursodeoxycholyl lysophosphatidylethanolamide protects against hepatic ischemia and reperfusion injury in mice.

Shock 2015 Apr;43(4):379-86

*Internal Medicine IV, Gastroenterology and Hepatology, University Heidelberg Hospital, Heidelberg, Germany; †Department of General Surgery and Laparoscopic Surgery, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China; ‡Mass Spectrometry Laboratory, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1097/SHK.0000000000000312DOI Listing
April 2015

Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins.

Exp Biol Med (Maywood) 2015 Feb 14;240(2):252-60. Epub 2014 Aug 14.

Department of Internal Medicine IV, Gastroenterology and Infectious Diseases, University Heidelberg Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1177/1535370214547157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935323PMC
February 2015

Ursodeoxycholyl lysophosphatidylethanolamide attenuates hepatofibrogenesis by impairment of TGF-β1/Smad2/3 signalling.

Br J Pharmacol 2014 Nov 5;171(22):5113-26. Epub 2014 Sep 5.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/bph.12837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253459PMC
November 2014

Plasma membrane phospholipase A2 controls hepatocellular fatty acid uptake and is responsive to pharmacological modulation: implications for nonalcoholic steatohepatitis.

FASEB J 2014 Jul 9;28(7):3159-70. Epub 2014 Apr 9.

Department of Gastroenterology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1096/fj.14-249763DOI Listing
July 2014

Ursodeoxycholyl lysophosphatidylethanolamide inhibits lipoapoptosis by shifting fatty acid pools toward monosaturated and polyunsaturated fatty acids in mouse hepatocytes.

Mol Pharmacol 2013 Nov 23;84(5):696-709. Epub 2013 Aug 23.

Department of Internal Medicine IV, Gastroenterology and Infectious Diseases, Im Neuenheimer Feld, Heidelberg, Germany (W.C., H.G.-S., A.P., W.S.); Institute of Clinical Chemistry and Laboratory Medicine, University of Regensburg, Regensburg, Germany (G.L., G.S.); and Department of Gastroenterology, Hangzhou First People's Hospital, Hangzhou, Zhejiang, People's Republic of China (W.X.).

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http://dx.doi.org/10.1124/mol.113.088039DOI Listing
November 2013

Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease.

Hepatology 2012 May 18;55(5):1369-78. Epub 2012 Mar 18.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hep.25531DOI Listing
May 2012

Comparison of different bile acid-phospholipid conjugates in acute hepatitis.

Eur J Clin Invest 2012 Feb 27;42(2):130-8. Epub 2011 Jun 27.

Department of Internal Medicine IV, Gastroenterology and Hepatology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1365-2362.2011.02563.xDOI Listing
February 2012

The synthetic bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide suppresses TNFα-induced liver injury.

J Hepatol 2011 Apr 27;54(4):674-84. Epub 2010 Sep 27.

Department of Internal Medicine IV, University of Heidelberg, 69120 Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01688278100082
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http://dx.doi.org/10.1016/j.jhep.2010.07.028DOI Listing
April 2011

Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent.

Hepatology 2009 Jul;50(1):143-54

Department of Internal Medicine IV, Gastroenterology and Infectious Diseases, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hep.22955DOI Listing
July 2009