Publications by authors named "Anil K Mantha"

32Publications

4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer's Disease.

ACS Chem Neurosci 2019 01 22;10(1):252-265. Epub 2018 Oct 22.

Laboratory of Organic and Medicinal Chemistry, Department of Pharmaceutical Sciences and Natural Products , Central University of Punjab , Bathinda , Punjab 151001 , India.

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http://dx.doi.org/10.1021/acschemneuro.8b00220DOI Listing
January 2019

Anticancer activity of dihydropyrazolo[1,5-c]quinazolines against rat C6 glioma cells via inhibition of topoisomerase II.

Arch Pharm (Weinheim) 2018 Jun 8;351(6):e1800023. Epub 2018 May 8.

Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, India.

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http://dx.doi.org/10.1002/ardp.201800023DOI Listing
June 2018

Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes.

Metab Brain Dis 2018 08 2;33(4):1307-1326. Epub 2018 May 2.

Department of Animal Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, 151 001, India.

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http://dx.doi.org/10.1007/s11011-018-0233-3DOI Listing
August 2018

Synthesis, biological evaluation and molecular modeling studies of phenyl-/benzhydrylpiperazine derivatives as potential MAO inhibitors.

Bioorg Chem 2018 04 16;77:252-262. Epub 2018 Jan 16.

Laboratory of Organic and Medicinal Chemistry, Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Punjab 151001, India. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2018.01.020DOI Listing
April 2018

APE1 modulates cellular responses to organophosphate pesticide-induced oxidative damage in non-small cell lung carcinoma A549 cells.

Mol Cell Biochem 2018 Apr 8;441(1-2):201-216. Epub 2017 Sep 8.

Centre for Animal Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, 151 001, India.

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http://dx.doi.org/10.1007/s11010-017-3186-7DOI Listing
April 2018

Curcumin revitalizes Amyloid beta (25-35)-induced and organophosphate pesticides pestered neurotoxicity in SH-SY5Y and IMR-32 cells via activation of APE1 and Nrf2.

Metab Brain Dis 2017 Dec 31;32(6):2045-2061. Epub 2017 Aug 31.

Center for Animal Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, 151 001, India.

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http://dx.doi.org/10.1007/s11011-017-0093-2DOI Listing
December 2017

An in vitro study ascertaining the role of HO and glucose oxidase in modulation of antioxidant potential and cancer cell survival mechanisms in glioblastoma U-87 MG cells.

Metab Brain Dis 2017 10 5;32(5):1705-1716. Epub 2017 Jul 5.

Center for Animal Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, 151 001, India.

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http://dx.doi.org/10.1007/s11011-017-0057-6DOI Listing
October 2017

Understanding human thiol dioxygenase enzymes: structure to function, and biology to pathology.

Int J Exp Pathol 2017 04 24;98(2):52-66. Epub 2017 Apr 24.

Center for Animal Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, India.

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http://dx.doi.org/10.1111/iep.12222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485369PMC
April 2017

Phytochemical Ginkgolide B Attenuates Amyloid-β1-42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells.

J Alzheimers Dis 2017 ;60(s1):S25-S40

Centre for Animal Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, India.

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http://dx.doi.org/10.3233/JAD-161086DOI Listing
April 2018

Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair.

Oncotarget 2016 11;7(46):75197-75209

Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.

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http://dx.doi.org/10.18632/oncotarget.12113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342734PMC
November 2016

Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies.

Biosens Bioelectron 2017 Feb 12;88:217-231. Epub 2016 Aug 12.

Centre for Animal Sciences, Central University of Punjab, Bathinda, 151001 India. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2016.08.028DOI Listing
February 2017

Ginkgolide B revamps neuroprotective role of apurinic/apyrimidinic endonuclease 1 and mitochondrial oxidative phosphorylation against Aβ25-35 -induced neurotoxicity in human neuroblastoma cells.

J Neurosci Res 2015 Jun 9;93(6):938-47. Epub 2015 Feb 9.

Centre for Biosciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab, India.

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http://dx.doi.org/10.1002/jnr.23565DOI Listing
June 2015

DNA repair and redox activities and inhibitors of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): a comparative analysis and their scope and limitations toward anticancer drug development.

J Med Chem 2014 Dec 15;57(24):10241-56. Epub 2014 Oct 15.

Laboratory for Drug Design and Synthesis, Centre for Chemical and Pharmaceutical Sciences, School of Basic and Applied Sciences, Central University of Punjab , Bathinda, 151001, Punjab, India.

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http://dx.doi.org/10.1021/jm500865uDOI Listing
December 2014

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions.

Exp Mol Med 2014 Jul 18;46:e106. Epub 2014 Jul 18.

1] Center for Biosciences, School of Basic and Applied Sciences, Central University of Punjab, Punjab, India [2] Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.

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http://dx.doi.org/10.1038/emm.2014.42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119211PMC
July 2014

Essential oils and their constituents as anticancer agents: a mechanistic view.

Biomed Res Int 2014 9;2014:154106. Epub 2014 Jun 9.

Centre for Environmental Science and Technology, School of Environment and Earth Sciences, Central University of Punjab, Bathinda, Punjab 151001, India.

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http://dx.doi.org/10.1155/2014/154106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070586PMC
March 2015

A short review on the implications of base excision repair pathway for neurons: relevance to neurodegenerative diseases.

Mitochondrion 2014 May 9;16:38-49. Epub 2013 Nov 9.

Department of Medical and Biological Sciences, University of Udine, 33100 Udine, Italy.

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http://dx.doi.org/10.1016/j.mito.2013.10.007DOI Listing
May 2014

Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.

J Neurosci Res 2012 Jun 20;90(6):1230-9. Epub 2012 Feb 20.

Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas, USA.

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http://dx.doi.org/10.1002/jnr.23018DOI Listing
June 2012

Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.

Mech Ageing Dev 2012 Apr 31;133(4):157-68. Epub 2012 Jan 31.

Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555-1079, USA.

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http://dx.doi.org/10.1016/j.mad.2012.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351531PMC
April 2012

MD simulation and experimental evidence for Mg²+ binding at the B site in human AP endonuclease 1.

Bioinformation 2011 14;7(4):184-98. Epub 2011 Oct 14.

Internal Medicine-Endocrinology Department, University of Texas Medical Branch, Galveston, TX 77555-1060, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218521PMC
http://dx.doi.org/10.6026/97320630007184DOI Listing
November 2011

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA.

Nucleic Acids Res 2009 Jul 28;37(12):3946-58. Epub 2009 Apr 28.

Chemistry Program, University of Northern British Columbia, 3333 University Way, Prince George, British Columbia V2N 4Z9, Canada.

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http://dx.doi.org/10.1093/nar/gkp275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709568PMC
July 2009

Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein.

Antioxid Redox Signal 2009 Mar;11(3):621-38

Department of Biochemistry and Molecular Biology, and Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston, Texas 77555, USA.

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http://dx.doi.org/10.1089/ars.2008.2198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933571PMC
March 2009

Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.

J Mol Biol 2008 May 3;379(1):28-37. Epub 2008 Apr 3.

Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.

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http://dx.doi.org/10.1016/j.jmb.2008.03.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708089PMC
May 2008

Membrane associated functions of neurokinin B (NKB) on Abeta (25-35) induced toxicity in aging rat brain synaptosomes.

Biogerontology 2006 Feb;7(1):19-33

Molecular and Structural Biophysics Laboratory, School of Life Sciences, Jawaharlal Nehru University, 110067, New Delhi, India.

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http://dx.doi.org/10.1007/s10522-005-6044-zDOI Listing
February 2006

Neuroprotective role of neurokinin B (NKB) on beta-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity.

Biogerontology 2006 Feb;7(1):1-17

Molecular and Structural Biophysics Laboratory, School of Life Sciences, Jawaharlal Nehru University, 110067, New Delhi, India.

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http://dx.doi.org/10.1007/s10522-005-6043-0DOI Listing
February 2006

Estradiol and progesterone treatments change the lipid profile in naturally menopausal rats from different age groups.

Biogerontology 2004 ;5(6):411-9

Hormone and Drug Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.

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http://dx.doi.org/10.1007/s10522-004-3190-7DOI Listing
April 2005

Three dimensional structure of mammalian tachykinin peptide neurokinin B bound to lipid micelles.

J Biomol Struct Dyn 2004 Oct;22(2):137-48

School of Life Sciences, Jawaharlal Nehru University, New Delhi--110 067, India.

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http://dx.doi.org/10.1080/07391102.2004.10506990DOI Listing
October 2004