Angus C Nairn

Angus C Nairn

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Angus C Nairn

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In Memoriam: David C. Gadsby, PhD.

J Gen Physiol 2019 Aug 16;151(8):967-969. Epub 2019 Jul 16.

Center for Neural Science, New York University, New York, NY.

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http://dx.doi.org/10.1085/jgp.201912400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683670PMC
August 2019

ProteomicsBrowser: MS/proteomics data visualization and investigation.

Bioinformatics 2019 Jul;35(13):2313-2314

Department of Biostatistics, School of Medicine, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596887PMC
July 2019

Editorial for Special Issue: Neuroproteomics.

Proteomes 2019 May 31;7(2). Epub 2019 May 31.

Yale/NIDA Neuroproteomics Center, New Haven, CT 06511, USA.

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http://dx.doi.org/10.3390/proteomes7020024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630506PMC
May 2019

cAMP regulation of protein phosphatases PP1 and PP2A in brain.

Biochim Biophys Acta Mol Cell Res 2019 01 18;1866(1):64-73. Epub 2018 Sep 18.

Department of Psychiatry, Yale University, New Haven, CT, United States of America.

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https://linkinghub.elsevier.com/retrieve/pii/S01674889183038
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http://dx.doi.org/10.1016/j.bbamcr.2018.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433392PMC
January 2019

Cell-Type-Specific Proteomics: A Neuroscience Perspective.

Proteomes 2018 Dec 9;6(4). Epub 2018 Dec 9.

Yale/NIDA Neuroproteomics Center, 300 George St., New Haven, CT 06511, USA.

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http://dx.doi.org/10.3390/proteomes6040051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313874PMC
December 2018

Striatal Signaling Regulated by the H3R Histamine Receptor in a Mouse Model of tic Pathophysiology.

Neuroscience 2018 11 29;392:172-179. Epub 2018 Sep 29.

Department of Psychiatry, Yale University, United States; Child Study Center, Yale University, United States; Interdepartental Neuroscience Program, Yale University, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03064522183064
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http://dx.doi.org/10.1016/j.neuroscience.2018.09.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204318PMC
November 2018

Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq.

J Proteome Res 2018 10 6;17(10):3431-3444. Epub 2018 Sep 6.

Department of Psychiatry , Yale School of Medicine, Connecticut Mental Health Center , 34 Park Street , New Haven , Connecticut 06519 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.8b00310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392456PMC
October 2018

Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo.

Proteomes 2018 Oct 15;6(4). Epub 2018 Oct 15.

Department of Psychiatry, Yale University School of Medicine, 34 Park Street, 3rd Floor Research, New Haven, CT 06508, USA.

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http://dx.doi.org/10.3390/proteomes6040042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313896PMC
October 2018

Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons.

J Biol Chem 2018 07 25;293(28):11179-11194. Epub 2018 May 25.

From the Department of Psychiatry, Yale University, New Haven, Connecticut 06520

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http://dx.doi.org/10.1074/jbc.RA117.001519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052221PMC
July 2018

The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology.

Alzheimers Dement 2018 05 11;14(5):680-691. Epub 2017 Dec 11.

Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178089PMC
May 2018

Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP.

Mol Neurobiol 2018 Apr 2;55(4):3096-3111. Epub 2017 May 2.

Child Study Center, Yale University School of Medicine, New Haven, USA.

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http://dx.doi.org/10.1007/s12035-017-0555-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668205PMC
April 2018

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.

Curr Biol 2018 04 22;28(7):1079-1089.e4. Epub 2018 Mar 22.

Department of Pharmacology and Physiology, Université de Montréal, and Hôpital du Sacré-Coeur de Montréal Research Center, Montreal, QC, Canada; Child Study Center, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.02.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901906PMC
April 2018

Making brain proteomics true to type.

Nat Biotechnol 2018 02;36(2):149-150

Department of Psychiatry, Yale School of Medicine, Connecticut Mental Health Center, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nbt.4077DOI Listing
February 2018

Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo.

Mol Biol Cell 2017 Dec 1;28(26):3844-3856. Epub 2017 Nov 1.

Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan

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http://dx.doi.org/10.1091/mbc.E17-05-0301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739299PMC
December 2017

Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1.

Mol Biol Cell 2017 Dec 1;28(26):3857-3869. Epub 2017 Nov 1.

Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan

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http://dx.doi.org/10.1091/mbc.E17-05-0303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739300PMC
December 2017

A multiregional proteomic survey of the postnatal human brain.

Nat Neurosci 2017 Dec 13;20(12):1787-1795. Epub 2017 Nov 13.

Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41593-017-0011-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894337PMC
December 2017

WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine.

Proc Natl Acad Sci U S A 2017 02 23;114(6):1395-1400. Epub 2017 Jan 23.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1621185114
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http://dx.doi.org/10.1073/pnas.1621185114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307471PMC
February 2017

Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function.

Neural Plast 2016 12;2016:8136925. Epub 2016 Apr 12.

Child Study Center, Yale University School of Medicine, New Haven, CT 06519, USA.

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http://dx.doi.org/10.1155/2016/8136925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844879PMC
December 2016

Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity.

F1000Res 2016 29;5. Epub 2016 Dec 29.

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, 06520, USA.

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http://dx.doi.org/10.12688/f1000research.8571.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642311PMC
December 2016

The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons.

J Biol Chem 2016 Sep 10;291(40):21042-21052. Epub 2016 Aug 10.

From the Departments Psychiatry and Interdepartmental Neuroscience Program, and Psychology, Child Study Center,

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http://dx.doi.org/10.1074/jbc.M116.731406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076514PMC
September 2016

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

Phosphorylation of ARPP19 by protein kinase A prevents meiosis resumption in Xenopus oocytes.

Nat Commun 2014 ;5:3318

1] Sorbonne Universités, UPMC Univ Paris 06, UMR7622-Biologie du Développement, Paris F-75005, France [2] CNRS, UMR7622-Biologie du Développement, Paris F-75005, France.

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http://dx.doi.org/10.1038/ncomms4318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014304PMC
November 2015

Contrasting features of ERK1/2 activity and synapsin I phosphorylation at the ERK1/2-dependent site in the rat brain in status epilepticus induced by kainic acid in vivo.

Brain Res 2015 Nov 28;1625:314-23. Epub 2015 Aug 28.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065-6399, USA.

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http://dx.doi.org/10.1016/j.brainres.2015.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637234PMC
November 2015

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor.

J Neurosci 2015 Nov;35(45):15082-7

Neuroscience Center of Excellence, School of Medicine, and Department of Cell Biology and Anatomy, Louisiana State University Health Science Center, New Orleans, Louisiana 70112,

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http://dx.doi.org/10.1523/JNEUROSCI.1865-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642240PMC
November 2015

Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations.

J Mol Cell Cardiol 2015 Oct 31;87:204-13. Epub 2015 Aug 31.

Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Howard Hughes Medical Institute, Cincinnati, OH 45229, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637224PMC
October 2015

APP intracellular domain-WAVE1 pathway reduces amyloid-β production.

Nat Med 2015 Sep 17;21(9):1054-9. Epub 2015 Aug 17.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.

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http://www.nature.com/articles/nm.3924
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http://dx.doi.org/10.1038/nm.3924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560977PMC
September 2015

The role of ventral striatal cAMP signaling in stress-induced behaviors.

Nat Neurosci 2015 Aug 20;18(8):1094-100. Epub 2015 Jul 20.

1] Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA. [2] Department of Neurology and Neurotherapeutics, The University of Texas Southwestern Medical Center, Dallas, Texas, USA. [3] Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/nn.4066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519694PMC
August 2015

Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins.

Proteomics 2015 Apr 12;15(7):1202-14. Epub 2015 Feb 12.

Yale/NIDA Neuroproteomics Center, New Haven, CT, USA; W.M. Keck Foundation Biotechnology Resource Laboratory, Yale University, New Haven, CT, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.

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http://doi.wiley.com/10.1002/pmic.201400353
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http://dx.doi.org/10.1002/pmic.201400353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698340PMC
April 2015

Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP.

Bioorg Med Chem Lett 2015 Mar 20;25(5):1044-6. Epub 2015 Jan 20.

Department of Chemistry, Yale University, New Haven, CT 06520, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334692PMC
March 2015

YPED: an integrated bioinformatics suite and database for mass spectrometry-based proteomics research.

Genomics Proteomics Bioinformatics 2015 Feb 21;13(1):25-35. Epub 2015 Feb 21.

W.M. Keck Foundation Biotechnology Resource Laboratory, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.gpb.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411476PMC
February 2015

Decoding neuroproteomics: integrating the genome, translatome and functional anatomy.

Nat Neurosci 2014 Nov 28;17(11):1491-9. Epub 2014 Oct 28.

Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.3829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737617PMC
November 2014

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

PLoS Biol 2014 Aug 5;12(8):e1001923. Epub 2014 Aug 5.

Child Study Center, Yale University, New Haven, Connecticut, United States of America; Department of Psychiatry, Yale University, New Haven, Connecticut, United States of America; Department of Neurobiology, Yale University, New Haven, Connecticut, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122355PMC
August 2014

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.

Proc Natl Acad Sci U S A 2014 Mar 3;111(11):4097-102. Epub 2014 Mar 3.

Departments of Molecular Pharmacology, Physiology, and Biotechnology, Molecular Biology, Cell Biology, and Biochemistry, and Chemistry, Brown University, Providence, RI 02912.

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http://www.pnas.org/content/111/11/4097.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.1317395111
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http://dx.doi.org/10.1073/pnas.1317395111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964120PMC
March 2014

Selective ablation of Ppp1cc gene in testicular germ cells causes oligo-teratozoospermia and infertility in mice.

Biol Reprod 2013 Nov 27;89(5):128. Epub 2013 Nov 27.

Department of Biological Sciences, Kent State University, Kent, Ohio.

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http://dx.doi.org/10.1095/biolreprod.113.110239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076382PMC
November 2013

Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5.

J Cell Biol 2013 Nov 4;203(3):521-35. Epub 2013 Nov 4.

Neuroscience Center, LSU Health Science Center, New Orleans, LA 70112.

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http://dx.doi.org/10.1083/jcb.201303035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824016PMC
November 2013

The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes.

J Cell Sci 2013 Sep 18;126(Pt 17):3916-26. Epub 2013 Jun 18.

UPMC Université Paris 06, UMR7622-Biologie du Développement, 9 quai Saint Bernard, 75005, Paris, France.

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http://dx.doi.org/10.1242/jcs.126599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757331PMC
September 2013

Selective knockout of the casein kinase 2 in d1 medium spiny neurons controls dopaminergic function.

Biol Psychiatry 2013 Jul 3;74(2):113-21. Epub 2013 Jan 3.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.biopsych.2012.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878430PMC
July 2013

Recent advances in quantitative neuroproteomics.

Methods 2013 Jun 25;61(3):186-218. Epub 2013 Apr 25.

Division of Molecular Psychiatry, Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, Yale University School of Medicine, New Haven, CT 06508, USA.

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http://dx.doi.org/10.1016/j.ymeth.2013.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891841PMC
June 2013

Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase.

J Biol Chem 2013 Jun 2;288(24):17803-11. Epub 2013 May 2.

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06508, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.477182
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http://dx.doi.org/10.1074/jbc.M113.477182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682579PMC
June 2013

Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons.

Proc Natl Acad Sci U S A 2013 Jun 20;110(23):9511-6. Epub 2013 May 20.

Unité Mixte de Recherche en Santé 839, Institut National de la Santé et de la Recherche Médicale, 75005 Paris, France.

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http://dx.doi.org/10.1073/pnas.1307116110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677456PMC
June 2013

Regulation of ERK1/2 mitogen-activated protein kinase by NMDA-receptor-induced seizure activity in cortical slices.

Brain Res 2013 Apr 16;1507:1-10. Epub 2013 Feb 16.

Department of Information Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8787, Japan.

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http://dx.doi.org/10.1016/j.brainres.2013.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648607PMC
April 2013

Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.

Adv Pharmacol 2012 ;64:303-25

Child Study Center, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1016/B978-0-12-394816-8.00009-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740556PMC
March 2013

Regulation of neurite outgrowth mediated by localized phosphorylation of protein translational factor eEF2 in growth cones.

Dev Neurobiol 2013 Mar 26;73(3):230-46. Epub 2012 Nov 26.

Division of Medical Life Sciences, Yokohama City University School of Medicine, Yokohama 236-0004, Japan.

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http://dx.doi.org/10.1002/dneu.22058DOI Listing
March 2013

Structural basis for protein phosphatase 1 regulation and specificity.

FEBS J 2013 Jan 24;280(2):596-611. Epub 2012 Feb 24.

Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08509.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350600PMC
January 2013

Protein phosphatases and Alzheimer's disease.

Prog Mol Biol Transl Sci 2012 ;106:343-79

Signum Biosciences, Monmouth Junction, New Jersey, USA.

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http://dx.doi.org/10.1016/B978-0-12-396456-4.00012-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739963PMC
July 2012

Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.

Psychopharmacology (Berl) 2012 Feb 11;219(4):1065-79. Epub 2011 Aug 11.

Department of Pharmacology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.

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http://dx.doi.org/10.1007/s00213-011-2436-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539205PMC
February 2012

Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits.

Eur J Neurosci 2012 Jan;35(2):300-8

Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06508, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2011.07956.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622044PMC
January 2012

Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory Proteins.

Curr Phys Chem 2012 Jan;2(1):107-114

Department of Molecular Pharmacology, Physiology and Biotechnology & Department of Chemistry, Brown University, Providence, RI 02912, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409662PMC
January 2012

Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization.

J Neurochem 2011 Nov 21;119(3):664-72. Epub 2011 Sep 21.

Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07450.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192910PMC
November 2011

Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex.

Biochemistry 2011 Feb 24;50(7):1238-46. Epub 2011 Jan 24.

Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island 02912, United States.

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http://dx.doi.org/10.1021/bi101774gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040262PMC
February 2011

Flexibility in the PP1:spinophilin holoenzyme.

FEBS Lett 2011 Jan 19;585(1):36-40. Epub 2010 Nov 19.

Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1016/j.febslet.2010.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017638PMC
January 2011

Serine/threonine protein phosphatase assays.

Curr Protoc Mol Biol 2010 Oct;Chapter 18:Unit18.18

The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1002/0471142727.mb1818s92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965627PMC
October 2010

Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization.

J Neurochem 2010 Jul 9;114(1):182-90. Epub 2010 Apr 9.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10065, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2010.06743.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945298PMC
July 2010

Evidence for the involvement of Lfc and Tctex-1 in axon formation.

J Neurosci 2010 May;30(19):6793-800

Instituto de Investigación Médica Mercedes y Martín Ferreyra-Consejo Nacional de Investigaciones Científicas y Técnicas, 5016 Cordoba, Argentina.

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http://dx.doi.org/10.1523/JNEUROSCI.5420-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845415PMC
May 2010

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.

Nat Struct Mol Biol 2010 Apr 21;17(4):459-64. Epub 2010 Mar 21.

Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1038/nsmb.1786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924587PMC
April 2010

Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.

Proc Natl Acad Sci U S A 2010 Mar 9;107(9):4401-6. Epub 2010 Feb 9.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.0915173107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840146PMC
March 2010

Dopamine-dependent tuning of striatal inhibitory synaptogenesis.

J Neurosci 2010 Feb;30(8):2935-50

Department of Pharmacology, The School of Pharmacy, University of London, London, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.4411-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930856PMC
February 2010

Prior chronic cocaine exposure in mice induces persistent alterations in cognitive function.

Behav Pharmacol 2009 Dec;20(8):695-704

Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, Ribicoff Research Facilities, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1097/FBP.0b013e328333a2bbDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380449PMC
December 2009

Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.

J Biol Chem 2009 Oct 3;284(40):27533-43. Epub 2009 Aug 3.

Experimental Pathology, Department of Laboratory Medicine, Lund University, CRC, 205 02 Malmö, Sweden.

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http://dx.doi.org/10.1074/jbc.M109.048884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785682PMC
October 2009

CK2 negatively regulates Galphas signaling.

Proc Natl Acad Sci U S A 2009 Aug 3;106(33):14096-101. Epub 2009 Aug 3.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.0906857106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729026PMC
August 2009

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.

Nat Cell Biol 2009 May 26;11(5):644-51. Epub 2009 Apr 26.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1038/ncb1871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788612PMC
May 2009

Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology.

Proc Natl Acad Sci U S A 2009 Mar 13;106(9):3531-6. Epub 2009 Feb 13.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA.

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http://dx.doi.org/10.1073/pnas.0813263106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651273PMC
March 2009

Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.

Proc Natl Acad Sci U S A 2009 Feb 6;106(8):2915-20. Epub 2009 Feb 6.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.0813179106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650365PMC
February 2009

Detailed structural characterization of unbound protein phosphatase 1 inhibitors.

Biochemistry 2008 Nov;47(47):12346-56

Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1021/bi801308yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645960PMC
November 2008