Angelo M De Marzo

Angelo M De Marzo

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Angelo M De Marzo

Publications by authors named "Angelo M De Marzo"

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Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis.

Am J Pathol 2019 Sep 6. Epub 2019 Sep 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.07.016DOI Listing
September 2019

Inflammation-associated pathologies in a case of prostate schistosomiasis: Implications for a causal role in prostate carcinogenesis.

Prostate 2019 Aug 18;79(11):1316-1325. Epub 2019 Jun 18.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23841DOI Listing
August 2019

Serum Urate, Genetic Variation, and Prostate Cancer Risk: Atherosclerosis Risk in Communities (ARIC) Study.

Cancer Epidemiol Biomarkers Prev 2019 Jul;28(7):1259-1261

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-19-0161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608724PMC
July 2019

Mannose Receptor-positive Macrophage Infiltration Correlates with Prostate Cancer Onset and Metastatic Castration-resistant Disease.

Eur Urol Oncol 2019 Jul 19;2(4):429-436. Epub 2018 Oct 19.

Department of Oncology, Johns Hopkins School of Medicine and The Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.euo.2018.09.014DOI Listing
July 2019

Cancer overdiagnosis: a biological challenge and clinical dilemma.

Nat Rev Cancer 2019 06;19(6):349-358

Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41568-019-0142-8DOI Listing
June 2019

TP53 missense mutation is associated with increased tumor-infiltrating T cells in primary prostate cancer.

Hum Pathol 2019 May 6;87:95-102. Epub 2019 Mar 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.humpath.2019.02.006DOI Listing
May 2019

Prostate Cancer Epigenetics: From Basic Mechanisms to Clinical Implications.

Cold Spring Harb Perspect Med 2019 Apr 1;9(4). Epub 2019 Apr 1.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21231.

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http://dx.doi.org/10.1101/cshperspect.a030445DOI Listing
April 2019

Effect of Preanalytic Variables on an Automated PTEN Immunohistochemistry Assay for Prostate Cancer.

Arch Pathol Lab Med 2019 Mar 8;143(3):338-348. Epub 2018 Oct 8.

From the Departments of Pathology (Drs Guedes, Morais, Fedor, Hicks, Gurel, De Marzo, and Lotan), Oncology (Drs Trock, De Marzo, and Lotan), and Urology (Drs Trock and De Marzo), Johns Hopkins University School of Medicine, Baltimore, Maryland; the Department of Pathology, New York University School of Medicine, New York, New York (Drs Melamed and Lee); the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Drs Gopalan and Fine); the Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California (Dr Knudsen); the Department of Pathology, University of Washington, Seattle (Dr True); and Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York (Dr Scher).

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http://dx.doi.org/10.5858/arpa.2018-0068-OADOI Listing
March 2019

A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth.

Prostate 2019 Feb 21;79(2):215-222. Epub 2018 Oct 21.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23726DOI Listing
February 2019

Prostatic Adenocarcinoma With Focal Pleomorphic Giant Cell Features: A Series of 30 Cases.

Am J Surg Pathol 2018 10;42(10):1286-1296

Department of Pathology, Johns Hopkins Medical Institute, Baltimore, MD.

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http://dx.doi.org/10.1097/PAS.0000000000001112DOI Listing
October 2018

Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy.

Small 2018 10 17;14(41):e1802565. Epub 2018 Sep 17.

Center for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1002/smll.201802565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286670PMC
October 2018

Characterization of novel cell lines derived from a MYC-driven murine model of lethal metastatic adenocarcinoma of the prostate.

Prostate 2018 09 30;78(13):992-1000. Epub 2018 May 30.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23657DOI Listing
September 2018

Detection of AR-V7 transcript with RNA in situ hybridization in human salivary duct cancer.

Oral Oncol 2018 09 28;84:134-136. Epub 2018 Jun 28.

Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2018.06.026DOI Listing
September 2018

Comprehensive Evaluation of Programmed Death-Ligand 1 Expression in Primary and Metastatic Prostate Cancer.

Am J Pathol 2018 06 22;188(6):1478-1485. Epub 2018 Mar 22.

Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins School of Medicine, Baltimore, Maryland; Department of Pathology, The Johns Hopkins School of Medicine, Baltimore, Maryland; Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440173117
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http://dx.doi.org/10.1016/j.ajpath.2018.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971230PMC
June 2018

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer.

Sci Rep 2018 May 8;8(1):7189. Epub 2018 May 8.

The James Buchanan Brady Urologic Institute and Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41598-018-25320-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940660PMC
May 2018

Clinical implications of PTEN loss in prostate cancer.

Nat Rev Urol 2018 04 20;15(4):222-234. Epub 2018 Feb 20.

Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

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http://www.nature.com/articles/nrurol.2018.9
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http://dx.doi.org/10.1038/nrurol.2018.9DOI Listing
April 2018

Profiling the Urinary Microbiome in Men with Positive versus Negative Biopsies for Prostate Cancer.

J Urol 2018 01 7;199(1):161-171. Epub 2017 Aug 7.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Sidney Kimmel Comprehensive Cancer Center, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937117PMC
January 2018

The inflammatory microenvironment and microbiome in prostate cancer development.

Nat Rev Urol 2018 01 31;15(1):11-24. Epub 2017 Oct 31.

Department of Pathology, Johns Hopkins University School of Medicine.

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http://dx.doi.org/10.1038/nrurol.2017.167DOI Listing
January 2018

BET inhibitors in metastatic prostate cancer: therapeutic implications and rational drug combinations.

Expert Opin Investig Drugs 2017 Dec 27;26(12):1391-1397. Epub 2017 Oct 27.

a Department of Oncology , Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/13543784.2017.1393518DOI Listing
December 2017

Deletion of tumor suppressors adenomatous polyposis coli and Smad4 in murine luminal epithelial cells causes invasive prostate cancer and loss of androgen receptor expression.

Oncotarget 2017 Oct 17;8(46):80265-80277. Epub 2017 May 17.

Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.18632/oncotarget.17919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655195PMC
October 2017

CXXC5 expression in prostate cancer: implications for cancer progression.

Int J Exp Pathol 2017 08;98(4):234-243

School of Medicine, University of Cartagena, Cartagena, Colombia.

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http://dx.doi.org/10.1111/iep.12241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639265PMC
August 2017

Prevalence and Prognostic Significance of PTEN Loss in African-American and European-American Men Undergoing Radical Prostatectomy.

Eur Urol 2017 05 28;71(5):697-700. Epub 2016 Jul 28.

Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274596PMC
May 2017

Novel Assay to Detect RNA Polymerase I Activity .

Mol Cancer Res 2017 05 23;15(5):577-584. Epub 2017 Jan 23.

Department of Pathology, Urology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802390PMC
May 2017

Low Intratumoral Mast Cells Are Associated With a Higher Risk of Prostate Cancer Recurrence.

Prostate 2017 03 21;77(4):412-424. Epub 2016 Nov 21.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23280DOI Listing
March 2017

The molecular underpinnings of prostate cancer: impacts on management and pathology practice.

J Pathol 2017 Jan 1;241(2):173-182. Epub 2016 Dec 1.

The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.

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http://dx.doi.org/10.1002/path.4826DOI Listing
January 2017

Differential long-term stability of microRNAs and RNU6B snRNA in 12-20 year old archived formalin-fixed paraffin-embedded specimens.

BMC Cancer 2017 01 6;17(1):32. Epub 2017 Jan 6.

The James Buchanan Brady Urologic Institute and Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1186/s12885-016-3008-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219687PMC
January 2017

Analytic Validation of RNA In Situ Hybridization (RISH) for AR and AR-V7 Expression in Human Prostate Cancer.

Clin Cancer Res 2016 Sep 10;22(18):4651-63. Epub 2016 May 10.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026571PMC
September 2016

ERG and PTEN status of isolated high-grade PIN occurring in cystoprostatectomy specimens without invasive prostatic adenocarcinoma.

Hum Pathol 2016 09 14;55:117-25. Epub 2016 May 14.

Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21231; Oncology, Johns Hopkins School of Medicine, Baltimore, MD 21231. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981542PMC
September 2016

Premalignancy in Prostate Cancer: Rethinking What we Know.

Cancer Prev Res (Phila) 2016 Aug 26;9(8):648-56. Epub 2016 Jan 26.

Departments of Pathology Oncology Urology The Johns Hopkins University School of Medicine, The Sidney Kimmel Comprehensive Cancer Center The Brady Urological Research Institute at Johns Hopkins, Johns Hopkins University, Baltimore, MD.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0431DOI Listing
August 2016

Regulating NKX3.1 stability and function: Post-translational modifications and structural determinants.

Prostate 2016 May 4;76(6):523-33. Epub 2016 Feb 4.

Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23144DOI Listing
May 2016

Inflammation in Benign Prostate Tissue and Prostate Cancer in the Finasteride Arm of the Prostate Cancer Prevention Trial.

Cancer Epidemiol Biomarkers Prev 2016 Mar 29;25(3):463-9. Epub 2015 Dec 29.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland. Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779655PMC
March 2016

A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer.

J Natl Cancer Inst 2016 Feb 27;108(2). Epub 2015 Nov 27.

Department of Epidemiology (TUA, AP, EME, TG, REG, KMW, JRR, HDS, ELG, MJS, LAM) and Department of Nutrition (ELG, MJS), Harvard T. H. Chan School of Public Health, Boston, MA; Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden (AP); Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA (REG); Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD (CLM, JLH, AMDM, TLL); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (JRR, ELG, MJS, LAM, KMW); Divisions of Preventive Medicine and Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA (HDS); Pathology Unit, Addarii Institute, S. Orsola-Malpighi Hospital, Bologna, Italy (MF); Department of Histopathology Research, Trinity College, Dublin, Ireland (RF, SF); Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA (ML); Department of Oncology (AMDM, TLL) and Department of Urology (ADMD), Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1093/jnci/djv346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862436PMC
February 2016

Identification of glycoproteins containing specific glycans using a lectin-chemical method.

Anal Chem 2015 20;87(9):4683-7. Epub 2015 Apr 20.

§Institute of Biophysics, Chinese Academy of Sciences, Beijing, China 100101.

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http://dx.doi.org/10.1021/ac504304vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496425PMC
December 2015

A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells.

Cancer Immunol Res 2015 Oct 5;3(10):1175-84. Epub 2015 Jun 5.

Department of Pathology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596748PMC
October 2015

Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells.

Cancer Prev Res (Phila) 2015 Aug 19;8(8):737-42. Epub 2015 May 19.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526348PMC
August 2015

Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)-Induced Cancer at Multiple Sites.

Cancer Prev Res (Phila) 2015 Aug 19;8(8):683-92. Epub 2015 May 19.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527940PMC
August 2015

Should Gleason 6 be labeled as cancer?

Curr Opin Urol 2015 May;25(3):238-45

aDepartment of Pathology bDepartment of Urology cDepartment of Oncology dThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins eThe Brady Urological Research Institute.

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http://dx.doi.org/10.1097/MOU.0000000000000165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878816PMC
May 2015

Overlap of CD44 expression between prostatic small cell carcinoma and acinar adenocarcinoma.

Hum Pathol 2015 Apr 31;46(4):554-7. Epub 2014 Dec 31.

Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, United States 21231; Department of Urology, The Johns Hopkins Hospital, Baltimore, MD, United States 21231; Department of Oncology, The Johns Hopkins Hospital, Baltimore, MD, United States 21231. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2014.12.007DOI Listing
April 2015

Diagnostic challenges of clonal heterogeneity in prostate cancer.

J Clin Oncol 2015 Mar 17;33(7):e38-40. Epub 2014 Mar 17.

Sidney Kimmel Comprehensive Cancer Center; and Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD

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http://dx.doi.org/10.1200/JCO.2013.50.3540DOI Listing
March 2015

Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas.

Mod Pathol 2015 Mar 12;28(3):446-56. Epub 2014 Sep 12.

1] Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA [2] Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/modpathol.2014.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344845PMC
March 2015

Utility of PTEN and ERG immunostaining for distinguishing high-grade PIN from intraductal carcinoma of the prostate on needle biopsy.

Am J Surg Pathol 2015 Feb;39(2):169-78

Departments of *Pathology ∥Oncology ¶Urology, Johns Hopkins Medical Institutions, Baltimore, MD †Division of Pathology, Integrated Medical Professionals, PLLC., Garden City, NY ‡Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH §Miraca Life Sciences, Irving, TX.

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http://pdfs.journals.lww.com/ajsp/2015/02000/Utility_of_PTEN
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293206PMC
February 2015

Prospective study of human herpesvirus type 8 serostatus and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial.

Cancer Causes Control 2015 Jan 31;26(1):35-44. Epub 2014 Oct 31.

Division of Public Health Sciences, Department of Surgery, The Alvin J. Siteman Cancer Center, Washington University School of Medicine, 660 S. Euclid Ave., Box 8100, Rm. 208S, St. Louis, MO, 63110, USA,

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http://dx.doi.org/10.1007/s10552-014-0480-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282945PMC
January 2015

AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer.

Cancer Res 2014 Dec 16;74(24):7198-204. Epub 2014 Oct 16.

Department of Medical Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts. The Broad Institute, Cambridge, Massachusetts. Division of Cancer Studies, King's College London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267915PMC
December 2014

A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II.

Cancer Epidemiol Biomarkers Prev 2014 Nov 22;23(11):2561-7. Epub 2014 Aug 22.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Department of Urology and James Buchanan Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648294PMC
November 2014

The role of inflammation in prostate cancer.

Adv Exp Med Biol 2014 ;816:153-81

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-3-0348-0837-8_7DOI Listing
September 2014

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.

N Engl J Med 2014 Sep 3;371(11):1028-38. Epub 2014 Sep 3.

From the Departments of Oncology (E.S.A., H.W., B.L., J.T.I., R.N., C.J.P., S.R.D., M.A.C., M.A.E.), Pathology (H.L.F., T.L.L., Q.Z., A.M.D.M.), and Urology (C.L., M.N., J.C.R., Yan Chen, W.B.I., J.L.), Johns Hopkins University School of Medicine, Baltimore; and Greehey Children's Cancer Research Institute (T.A.M., Yidong Chen) and the Department of Epidemiology and Biostatistics (Yidong Chen), University of Texas Health Science Center at San Antonio, San Antonio.

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http://dx.doi.org/10.1056/NEJMoa1315815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201502PMC
September 2014

MSMB variation and prostate cancer risk: clues towards a possible fungal etiology.

Prostate 2014 May 24;74(6):569-78. Epub 2014 Jan 24.

Division of Public Health Sciences and the Alvin J. Siteman Cancer Center, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1002/pros.22778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037912PMC
May 2014

Long interspersed element-1 protein expression is a hallmark of many human cancers.

Am J Pathol 2014 May 6;184(5):1280-6. Epub 2014 Mar 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005969PMC
May 2014

Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial.

Cancer Epidemiol Biomarkers Prev 2014 May 18;23(5):847-56. Epub 2014 Apr 18.

Authors' Affiliations: Departments of Pathology and Immunology; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins School of Medicine; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore; Division of Cancer Prevention, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, Maryland; University of Colorado School of Medicine, Aurora, Colorado; Department of Urology, University of Texas Health Sciences Center San Antonio, San Antonio; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas; SWOG Statistical Center; Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Moores Cancer Center, University of California San Diego, La Jolla, California; and Division of Public Health Sciences and The Alvin J. Siteman Cancer Center, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-1126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012292PMC
May 2014

Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma.

Clin Cancer Res 2014 Feb 9;20(4):890-903. Epub 2013 Dec 9.

Authors' Affiliations: Pathology, Department of Pathology, Henry Ford Health System, Detroit, Michigan; Oncology, and Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931005PMC
February 2014

Infections and inflammation in prostate cancer.

Am J Clin Exp Urol 2013 Dec;1(1):3-11

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 ; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219279PMC
December 2013