Angela Simpson

Angela Simpson

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Angela Simpson

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Spidroins and Silk Fibers of Aquatic Spiders.

Sci Rep 2019 Sep 20;9(1):13656. Epub 2019 Sep 20.

Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, CA, 92591, USA.

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http://dx.doi.org/10.1038/s41598-019-49587-yDOI Listing
September 2019

Dust-mite inducing asthma: what advice can be given to patients?

Expert Rev Respir Med 2019 Aug 19:1-8. Epub 2019 Aug 19.

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester , UK.

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http://dx.doi.org/10.1080/17476348.2019.1651647DOI Listing
August 2019

Differential associations of allergic disease genetic variants with developmental profiles of eczema, wheeze and rhinitis.

Clin Exp Allergy 2019 Aug 23. Epub 2019 Aug 23.

MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1111/cea.13485DOI Listing
August 2019

Does understanding endotypes translate to better asthma management options for all?

J Allergy Clin Immunol 2019 Jul 27;144(1):25-33. Epub 2019 May 27.

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2019.05.016DOI Listing
July 2019

A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity.

Authors:
Jonathan P Bradfield Suzanne Vogelezang Janine F Felix Alessandra Chesi Øyvind Helgeland Momoko Horikoshi Ville Karhunen Estelle Lowry Diana L Cousminer Tarunveer S Ahluwalia Elisabeth Thiering Eileen Tai-Hui Boh Mohammad H Zafarmand Natalia Vilor-Tejedor Carol A Wang Raimo Joro Zhanghua Chen William J Gauderman Niina Pitkänen Esteban J Parra Lindsay Fernandez-Rhodes Akram Alyass Claire Monnereau John A Curtin Christian T Have Shana E McCormack Mette Hollensted Christine Frithioff-Bøjsøe Adan Valladares-Salgado Jesus Peralta-Romero Yik-Ying Teo Marie Standl Jaakko T Leinonen Jens-Christian Holm Triinu Peters Jesus Vioque Martine Vrijheid Angela Simpson Adnan Custovic Marc Vaudel Mickaël Canouil Virpi Lindi Mustafa Atalay Mika Kähönen Olli T Raitakari Barbera D C van Schaik Robert I Berkowitz Shelley A Cole V Saroja Voruganti Yujie Wang Heather M Highland Anthony G Comuzzie Nancy F Butte Anne E Justice Sheila Gahagan Estela Blanco Terho Lehtimäki Timo A Lakka Johannes Hebebrand Amélie Bonnefond Niels Grarup Philippe Froguel Leo-Pekka Lyytikäinen Miguel Cruz Sayuko Kobes Robert L Hanson Babette S Zemel Anke Hinney Koon K Teo David Meyre Kari E North Frank D Gilliland Hans Bisgaard Mariona Bustamante Klaus Bonnelykke Craig E Pennell Fernando Rivadeneira André G Uitterlinden Leslie J Baier Tanja G M Vrijkotte Joachim Heinrich Thorkild I A Sørensen Seang-Mei Saw Oluf Pedersen Torben Hansen Johan Eriksson Elisabeth Widén Mark I McCarthy Pål R Njølstad Christine Power Elina Hyppönen Sylvain Sebert Christopher D Brown Marjo-Riitta Järvelin Nicholas J Timpson Stefan Johansson Hakon Hakonarson Vincent W V Jaddoe Struan F A Grant

Hum Mol Genet 2019 Jul 5. Epub 2019 Jul 5.

Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/hmg/ddz161DOI Listing
July 2019

Understanding problematic eating in out-of-home care: The role of attachment and emotion regulation.

Appetite 2019 Apr 26;135:33-42. Epub 2018 Dec 26.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Locked Bag 29, Clayton, Vic 3168, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2018.12.027DOI Listing
April 2019

Individual risk assessment tool for school-age asthma prediction in UK birth cohort.

Clin Exp Allergy 2019 Mar 4;49(3):292-298. Epub 2019 Jan 4.

Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1111/cea.13319
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http://dx.doi.org/10.1111/cea.13319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446726PMC
March 2019

Evolution of IgE responses to multiple allergen components throughout childhood.

J Allergy Clin Immunol 2018 10 9;142(4):1322-1330. Epub 2018 Feb 9.

Section of Paediatrics, Department of Medicine, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170973PMC
October 2018

Vitamin D receptor genotype influences risk of upper respiratory infection.

Br J Nutr 2018 10 22;120(8):891-900. Epub 2018 Aug 22.

1Centre for Primary Care and Public Health, Barts and The London School of Medicine and Dentistry,Queen Mary University of London,London E1 2AB,UK.

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http://dx.doi.org/10.1017/S000711451800209XDOI Listing
October 2018

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0197-6DOI Listing
September 2018

Corticosteroid treatment is associated with increased filamentous fungal burden in allergic fungal disease.

J Allergy Clin Immunol 2018 08 6;142(2):407-414. Epub 2017 Nov 6.

Manchester Fungal Infection Group, Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust (Wythenshawe), Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.09.039DOI Listing
August 2018

Mast cell activation test in the diagnosis of allergic disease and anaphylaxis.

J Allergy Clin Immunol 2018 08 5;142(2):485-496.e16. Epub 2018 Mar 5.

Division of Musculoskeletal and Dermatological Sciences & Manchester Collaborative Centre for Inflammation Research (MCCIR), School of Biological Sciences, University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075471PMC
August 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0157-1DOI Listing
August 2018

Cat ownership, cat allergen exposure, and trajectories of sensitization and asthma throughout childhood.

J Allergy Clin Immunol 2018 02 28;141(2):820-822.e7. Epub 2017 Oct 28.

Section of Paediatrics, Department of Medicine, Imperial College, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792051PMC
February 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Intraspecific trait variation can weaken interspecific trait correlations when assessing the whole-plant economic spectrum.

Ecol Evol 2017 11 21;7(21):8936-8949. Epub 2017 Sep 21.

Environmental Research Institute School of Science University of Waikato Hamilton New Zealand.

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http://dx.doi.org/10.1002/ece3.3447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677476PMC
November 2017

"It's not as easy as saying, 'just get them to eat more veggies'": Exploring healthy eating in residential care in Australia.

Appetite 2017 10 8;117:275-283. Epub 2017 Jul 8.

School of Psychology, Deakin University, 221 Burwood Hwy, Burwood, Victoria, 3124, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2017.07.004DOI Listing
October 2017

Diagnosis of asthma in symptomatic children based on measures of lung function: an analysis of data from a population-based birth cohort study.

Lancet Child Adolesc Health 2017 Oct;1(2):114-123

Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, University Hospital of South Manchester NHS Foundation Trust, University of Manchester, Manchester, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23524642173000
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http://dx.doi.org/10.1016/S2352-4642(17)30008-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616137PMC
October 2017

Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers.

J Allergy Clin Immunol 2017 Aug 21;140(2):534-542. Epub 2016 Dec 21.

Asthma and Airway Disease Research Center, University of Arizona, Tucson, Ariz; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, Ariz; Arizona Center for the Biology of Complex Diseases, University of Arizona, Tucson, Ariz; Bio5 Institute, University of Arizona, Tucson, Ariz. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479765PMC
August 2017

A protocol for a systematic review to identify allergenic tree nuts and the molecules responsible for their allergenic properties.

Food Chem Toxicol 2017 Aug 5;106(Pt A):411-416. Epub 2017 Jun 5.

Manchester Institute of Biotechnology, Manchester M17DN, UK; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Manchester M17DN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2017.06.004DOI Listing
August 2017

Preventing Severe Asthma Exacerbations in Children. A Randomized Trial of Mite-Impermeable Bedcovers.

Am J Respir Crit Care Med 2017 07;196(2):150-158

1 Division of Infection, Immunity and Respiratory Medicine, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201609-1966OCDOI Listing
July 2017

Disaggregating asthma: Big investigation versus big data.

J Allergy Clin Immunol 2017 02 18;139(2):400-407. Epub 2016 Nov 18.

Department of Paediatrics, Imperial College, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292995PMC
February 2017

An eHealth Approach to Reporting Allergic Reactions to Food and Closing the Knowledge Gap.

Stud Health Technol Inform 2015 ;216:320-4

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, UK.

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December 2016

Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study.

Allergy Asthma Clin Immunol 2016 27;12:47. Epub 2016 Sep 27.

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1186/s13223-016-0152-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037889PMC
September 2016

After 30 years of dissemination, have we achieved sustained practice change in motivational interviewing?

Addiction 2016 07 28;111(7):1144-50. Epub 2015 Jul 28.

Turning Point, Eastern Health, Victoria, Australia.

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http://dx.doi.org/10.1111/add.13014DOI Listing
July 2016

Continuing the conversation: 30 years of motivational interviewing dissemination.

Addiction 2016 07;111(7):1158-9

Turning Point, Eastern Health, Victoria, Australia.

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http://dx.doi.org/10.1111/add.13414DOI Listing
July 2016

Age, sex and the association between skin test responses and IgE titres with asthma.

Pediatr Allergy Immunol 2016 05 8;27(3):313-9. Epub 2016 Feb 8.

Department of Paediatrics, Imperial College London, London, UK.

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http://dx.doi.org/10.1111/pai.12534DOI Listing
May 2016

Insoluble and soluble roasted walnut proteins retain antibody reactivity.

Food Chem 2016 Mar 3;194:1013-21. Epub 2015 Sep 3.

Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre and Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester & Respiratory and Allergy Clinical Research Facility, Education and Research Centre, University Hospital of South Manchester NHS Foundation Trust, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.

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http://dx.doi.org/10.1016/j.foodchem.2015.08.119DOI Listing
March 2016

Distinguishing benign from pathologic TH2 immunity in atopic children.

J Allergy Clin Immunol 2016 Feb 27;137(2):379-87. Epub 2015 Oct 27.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2015.08.044DOI Listing
February 2016

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

Authors:
Janine F Felix Jonathan P Bradfield Claire Monnereau Ralf J P van der Valk Evie Stergiakouli Alessandra Chesi Romy Gaillard Bjarke Feenstra Elisabeth Thiering Eskil Kreiner-Møller Anubha Mahajan Niina Pitkänen Raimo Joro Alana Cavadino Ville Huikari Steve Franks Maria M Groen-Blokhuis Diana L Cousminer Julie A Marsh Terho Lehtimäki John A Curtin Jesus Vioque Tarunveer S Ahluwalia Ronny Myhre Thomas S Price Natalia Vilor-Tejedor Loïc Yengo Niels Grarup Ioanna Ntalla Wei Ang Mustafa Atalay Hans Bisgaard Alexandra I Blakemore Amelie Bonnefond Lisbeth Carstensen Johan Eriksson Claudia Flexeder Lude Franke Frank Geller Mandy Geserick Anna-Liisa Hartikainen Claire M A Haworth Joel N Hirschhorn Albert Hofman Jens-Christian Holm Momoko Horikoshi Jouke Jan Hottenga Jinyan Huang Haja N Kadarmideen Mika Kähönen Wieland Kiess Hanna-Maaria Lakka Timo A Lakka Alexandra M Lewin Liming Liang Leo-Pekka Lyytikäinen Baoshan Ma Per Magnus Shana E McCormack George McMahon Frank D Mentch Christel M Middeldorp Clare S Murray Katja Pahkala Tune H Pers Roland Pfäffle Dirkje S Postma Christine Power Angela Simpson Verena Sengpiel Carla M T Tiesler Maties Torrent André G Uitterlinden Joyce B van Meurs Rebecca Vinding Johannes Waage Jane Wardle Eleftheria Zeggini Babette S Zemel George V Dedoussis Oluf Pedersen Philippe Froguel Jordi Sunyer Robert Plomin Bo Jacobsson Torben Hansen Juan R Gonzalez Adnan Custovic Olli T Raitakari Craig E Pennell Elisabeth Widén Dorret I Boomsma Gerard H Koppelman Sylvain Sebert Marjo-Riitta Järvelin Elina Hyppönen Mark I McCarthy Virpi Lindi Niinikoski Harri Antje Körner Klaus Bønnelykke Joachim Heinrich Mads Melbye Fernando Rivadeneira Hakon Hakonarson Susan M Ring George Davey Smith Thorkild I A Sørensen Nicholas J Timpson Struan F A Grant Vincent W V Jaddoe

Hum Mol Genet 2016 Jan 24;25(2):389-403. Epub 2015 Nov 24.

The Generation R Study Group, Department of Pediatrics, Department of Epidemiology.

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http://hmg.oxfordjournals.org/content/early/2015/12/16/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854022PMC
January 2016

Evolution pathways of IgE responses to grass and mite allergens throughout childhood.

J Allergy Clin Immunol 2015 Dec 8;136(6):1645-1652.e8. Epub 2015 May 8.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester & University Hospital of South Manchester, Manchester, United Kingdom; Centre for Health Informatics, Institute of Population Health, University of Manchester, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.03.041DOI Listing
December 2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Patterns of IgE responses to multiple allergen components and clinical symptoms at age 11 years.

J Allergy Clin Immunol 2015 Nov 30;136(5):1224-31. Epub 2015 Apr 30.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, University of Manchester & University Hospital of South Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2015.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649774PMC
November 2015

Atopic Dermatitis and Respiratory Allergy: What is the Link.

Curr Dermatol Rep 2015;4(4):221-227. Epub 2015 Sep 28.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s13671-015-0121-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635175PMC
September 2015

The Study Team for Early Life Asthma Research (STELAR) consortium 'Asthma e-lab': team science bringing data, methods and investigators together.

Thorax 2015 Aug 24;70(8):799-801. Epub 2015 Mar 24.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2015-206781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515979PMC
August 2015

Elevated levels of the neutrophil chemoattractant pro-platelet basic protein in macrophages from individuals with chronic and allergic aspergillosis.

J Infect Dis 2015 Feb 5;211(4):651-60. Epub 2014 Sep 5.

Manchester Fungal Infection Group Manchester Academic Health Science Centre National Aspergillosis Centre, University Hospital South Manchester NHS Foundation Trust NIHR South Manchester Respiratory and Allergy Clinical Research Facility, United Kingdom.

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http://dx.doi.org/10.1093/infdis/jiu490DOI Listing
February 2015

A novel common variant in DCST2 is associated with length in early life and height in adulthood.

Authors:
Ralf J P van der Valk Eskil Kreiner-Møller Marjolein N Kooijman Mònica Guxens Evangelia Stergiakouli Annika Sääf Jonathan P Bradfield Frank Geller M Geoffrey Hayes Diana L Cousminer Antje Körner Elisabeth Thiering John A Curtin Ronny Myhre Ville Huikari Raimo Joro Marjan Kerkhof Nicole M Warrington Niina Pitkänen Ioanna Ntalla Momoko Horikoshi Riitta Veijola Rachel M Freathy Yik-Ying Teo Sheila J Barton David M Evans John P Kemp Beate St Pourcain Susan M Ring George Davey Smith Anna Bergström Inger Kull Hakon Hakonarson Frank D Mentch Hans Bisgaard Bo Chawes Jakob Stokholm Johannes Waage Patrick Eriksen Astrid Sevelsted Mads Melbye Cornelia M van Duijn Carolina Medina-Gomez Albert Hofman Johan C de Jongste H Rob Taal André G Uitterlinden Loren L Armstrong Johan Eriksson Aarno Palotie Mariona Bustamante Xavier Estivill Juan R Gonzalez Sabrina Llop Wieland Kiess Anubha Mahajan Claudia Flexeder Carla M T Tiesler Clare S Murray Angela Simpson Per Magnus Verena Sengpiel Anna-Liisa Hartikainen Sirkka Keinanen-Kiukaanniemi Alexandra Lewin Alexessander Da Silva Couto Alves Alexandra I Blakemore Jessica L Buxton Marika Kaakinen Alina Rodriguez Sylvain Sebert Marja Vaarasmaki Timo Lakka Virpi Lindi Ulrike Gehring Dirkje S Postma Wei Ang John P Newnham Leo-Pekka Lyytikäinen Katja Pahkala Olli T Raitakari Kalliope Panoutsopoulou Eleftheria Zeggini Dorret I Boomsma Maria Groen-Blokhuis Jorma Ilonen Lude Franke Joel N Hirschhorn Tune H Pers Liming Liang Jinyan Huang Berthold Hocher Mikael Knip Seang-Mei Saw John W Holloway Erik Melén Struan F A Grant Bjarke Feenstra William L Lowe Elisabeth Widén Elena Sergeyev Harald Grallert Adnan Custovic Bo Jacobsson Marjo-Riitta Jarvelin Mustafa Atalay Gerard H Koppelman Craig E Pennell Harri Niinikoski George V Dedoussis Mark I Mccarthy Timothy M Frayling Jordi Sunyer Nicholas J Timpson Fernando Rivadeneira Klaus Bønnelykke Vincent W V Jaddoe

Hum Mol Genet 2015 Feb 3;24(4):1155-68. Epub 2014 Oct 3.

Department of Epidemiology, Department of Paediatrics, The Generation R Study Group,

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February 2015

Characterization of low molecular weight allergens from English walnut (Juglans regia).

J Agric Food Chem 2014 Dec 20;62(48):11767-75. Epub 2014 Nov 20.

143 Food Industry Complex, Food Allergy Research and Resource Program, Department of Food Science and Technology, University of Nebraska-Lincoln , Lincoln, Nebraska 68583-0919, United States.

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December 2014

Differing associations of BMI and body fat with asthma and lung function in children.

Pediatr Pulmonol 2014 Nov 25;49(11):1049-57. Epub 2013 Oct 25.

Manchester Academic Health Science Centre, University of Manchester, University Hospital of South Manchester, NHS Foundation Trust, Manchester, UK.

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November 2014

Genetic variants in endotoxin signalling pathway, domestic endotoxin exposure and asthma exacerbations.

Pediatr Allergy Immunol 2014 Oct;25(6):552-7

General Hospital "Dr Josip Bencevic" Slavonski Brod, University of Osijek, Osijek, Croatia.

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October 2014

Cross-sectional association of dietary patterns with asthma and atopic sensitization in childhood - in a cohort study.

Pediatr Allergy Immunol 2014 Oct;25(6):565-71

School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1111/pai.12276DOI Listing
October 2014

Allergy and asthma prevention 2014.

Pediatr Allergy Immunol 2014 Oct;25(6):516-33

Pediatric Pulmonology and Allergy Unit, Children's Hospital La Fe, Instituto de Investigacion La Fe, Valencia, Spain.

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http://dx.doi.org/10.1111/pai.12272DOI Listing
October 2014

Developmental profiles of eczema, wheeze, and rhinitis: two population-based birth cohort studies.

PLoS Med 2014 Oct 21;11(10):e1001748. Epub 2014 Oct 21.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, United Kingdom.

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October 2014

Elemental composition of particulate matter and the association with lung function.

Epidemiology 2014 Sep;25(5):648-57

From the aInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; bDepartment of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; cUniversity of Basel, Basel, Switzerland; dKarolinska Institute, Institute of Environmental Medicine, Stockholm, Sweden; eCentre for Occupational and Environmental Health, University of Manchester, Manchester, United Kingdom; fJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; gUniversity of Manchester, Manchester Academic Health Science Centre, Institute of Inflammation and Repair, University Hospital of South Manchester NHS Foundation Trust, Wythenshawe Hospital, Manchester, United Kingdom; hHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany; iUniversity of Augsburg, Environmental Science Center, Augsburg, Germany; jHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany; kSchool of Population and Public Health, University of British Columbia, Vancouver, Canada; lIUF Leibniz Research Institute for Environmental Medicine, University of Düsseldorf, Düsseldorf, Germany; mMedical Faculty, Heinrich-Heine University of Düsseldorf, Düsseldorf, Germany; nMRC-HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; oTNO, Netherlands Organization for Applied Scientific Research, Utrecht, The Netherlands; pUniversity of Groningen, University Medical Center Groningen, GRIAC Research Institute and Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen, The Netherlands; qAir Quality & Sustainable Nanotechnology, IUTA e.V., and CENIDE at the University of Duisburg-Essen, Duisburg, Germany; and rDepartment of Environmental and Occupational Health

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September 2014

Assessing the association of early life antibiotic prescription with asthma exacerbations, impaired antiviral immunity, and genetic variants in 17q21: a population-based birth cohort study.

Lancet Respir Med 2014 Aug 14;2(8):621-30. Epub 2014 May 14.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester & University Hospital of South Manchester, Manchester, UK. Electronic address:

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August 2014

Trajectories of lung function during childhood.

Am J Respir Crit Care Med 2014 May;189(9):1101-9

1 Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, United Kingdom.

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May 2014

Challenges in interpreting allergen microarrays in relation to clinical symptoms: a machine learning approach.

Pediatr Allergy Immunol 2014 Feb 16;25(1):71-9. Epub 2013 Oct 16.

Centre for Health Informatics, Institute of Population Health, University of Manchester, Manchester, UK; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282342PMC
February 2014

Effects of long-term exposure to PM10 and NO2 on asthma and wheeze in a prospective birth cohort.

J Epidemiol Community Health 2014 Jan 2;68(1):21-8. Epub 2013 Sep 2.

Centre for Occupational & Environmental Health, Centre for Epidemiology, Institute of Population Health, Manchester Academic Health Sciences Centre, The University of Manchester, , Manchester, UK.

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http://dx.doi.org/10.1136/jech-2013-202681DOI Listing
January 2014

Challenges in interpreting wheeze phenotypes: the clinical implications of statistical learning techniques.

Am J Respir Crit Care Med 2014 Jan;189(2):121-3

1 Institute of Inflammation and Repair University of Manchester and University Hospital of South Manchester Manchester, United Kingdom and.

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January 2014

Long-term exposure to PM10 and NO2 in association with lung volume and airway resistance in the MAAS birth cohort.

Environ Health Perspect 2013 Oct 18;121(10):1232-8. Epub 2013 Jun 18.

Centre for Occupational and Environmental Health, Health Sciences Group, School of Community-Based Medicine, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1289/ehp.1205961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801452PMC
October 2013

Characterizing wheeze phenotypes to identify endotypes of childhood asthma, and the implications for future management.

Expert Rev Clin Immunol 2013 Oct;9(10):921-36

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, UK.

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October 2013

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing.

J Allergy Clin Immunol 2013 Sep 29;132(3):575-583.e12. Epub 2013 Jul 29.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, United Kingdom.

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September 2013

Interaction between glutathione S-transferase variants, maternal smoking and childhood wheezing changes with age.

Pediatr Allergy Immunol 2013 Aug 3;24(5):501-8. Epub 2013 Jun 3.

Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, The University of Manchester, Manchester, UK.

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August 2013

17q12-21 and asthma: interactions with early-life environmental exposures.

Ann Allergy Asthma Immunol 2013 May 6;110(5):347-353.e2. Epub 2013 Mar 6.

General Hospital Dr Josip Bencevic Slavonski Brod, University of Osijek, Osijek, Croatia.

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May 2013

Pediatric asthma and development of atopy.

Curr Opin Allergy Clin Immunol 2013 Apr;13(2):173-80

University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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April 2013

Asthma severity, polymorphisms in 20p13 and their interaction with tobacco smoke exposure.

Pediatr Allergy Immunol 2013 Feb;24(1):10-8

General Hospital Dr Josip Bencevic Slavonski Brod, University of Osijek, Osijek, Croatia.

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February 2013

17q12-21 variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom.

Ann Allergy Asthma Immunol 2012 Jun 11;108(6):402-411.e9. Epub 2012 Apr 11.

Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, The University of Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.anai.2012.03.002DOI Listing
June 2012

Gene-environment interactions in the development of asthma and atopy.

Expert Rev Respir Med 2012 Jun;6(3):301-8

The University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester, M23 9LT, UK.

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http://dx.doi.org/10.1586/ers.12.24DOI Listing
June 2012

Quantification of atopy, lung function and airway hypersensitivity in adults.

Clin Transl Allergy 2011 Dec 12;1(1):16. Epub 2011 Dec 12.

The University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339334PMC
December 2011

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Chih-Mei Chen Adaikalavan Ramasamy Klaus Bønnelykke Liesbeth Duijts Manuel A Ferreira Alexessander Couto Alves Jacob P Thyssen Eva Albrecht Hansjörg Baurecht Bjarke Feenstra Patrick M A Sleiman Pirro Hysi Nicole M Warrington Ivan Curjuric Ronny Myhre John A Curtin Maria M Groen-Blokhuis Marjan Kerkhof Annika Sääf Andre Franke David Ellinghaus Regina Fölster-Holst Emmanouil Dermitzakis Stephen B Montgomery Holger Prokisch Katharina Heim Anna-Liisa Hartikainen Anneli Pouta Juha Pekkanen Alexandra I F Blakemore Jessica L Buxton Marika Kaakinen David L Duffy Pamela A Madden Andrew C Heath Grant W Montgomery Philip J Thompson Melanie C Matheson Peter Le Souëf Beate St Pourcain George Davey Smith John Henderson John P Kemp Nicholas J Timpson Panos Deloukas Susan M Ring H-Erich Wichmann Martina Müller-Nurasyid Natalija Novak Norman Klopp Elke Rodríguez Wendy McArdle Allan Linneberg Torkil Menné Ellen A Nohr Albert Hofman André G Uitterlinden Cornélia M van Duijn Fernando Rivadeneira Johan C de Jongste Ralf J P van der Valk Matthias Wjst Rain Jogi Frank Geller Heather A Boyd Jeffrey C Murray Cecilia Kim Frank Mentch Michael March Massimo Mangino Tim D Spector Veronique Bataille Craig E Pennell Patrick G Holt Peter Sly Carla M T Tiesler Elisabeth Thiering Thomas Illig Medea Imboden Wenche Nystad Angela Simpson Jouke-Jan Hottenga Dirkje Postma Gerard H Koppelman Henriette A Smit Cilla Söderhäll Bo Chawes Eskil Kreiner-Møller Hans Bisgaard Erik Melén Dorret I Boomsma Adnan Custovic Bo Jacobsson Nicole M Probst-Hensch Lyle J Palmer Daniel Glass Hakon Hakonarson Mads Melbye Deborah L Jarvis Vincent W V Jaddoe Christian Gieger David P Strachan Nicholas G Martin Marjo-Riitta Jarvelin Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2011 Dec 25;44(2):187-92. Epub 2011 Dec 25.

Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK.

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December 2011

Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood.

J Allergy Clin Immunol 2011 Jun 13;127(6):1480-5. Epub 2011 Apr 13.

University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom.

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June 2011

Effect of day care attendance on sensitization and atopic wheezing differs by Toll-like receptor 2 genotype in 2 population-based birth cohort studies.

J Allergy Clin Immunol 2011 Feb;127(2):390-397.e1-9

University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075116PMC
February 2011

Increased serum-soluble interleukin-5 receptor alpha level precedes the development of eczema in children.

Pediatr Allergy Immunol 2010 Nov 23;21(7):1052-8. Epub 2010 Aug 23.

The University of Manchester, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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November 2010

Allergy is an important factor in asthma exacerbation: a pro/con debate.

Respirology 2010 Oct 27;15(7):1021-7. Epub 2010 Aug 27.

The University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, Manchester, UK.

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October 2010

Effect of household pet ownership on infant immune response and subsequent sensitization.

Authors:
Angela Simpson

J Asthma Allergy 2010 Aug 30;3:131-7. Epub 2010 Aug 30.

Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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August 2010

Beyond atopy: multiple patterns of sensitization in relation to asthma in a birth cohort study.

Am J Respir Crit Care Med 2010 Jun 18;181(11):1200-6. Epub 2010 Feb 18.

The University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom.

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June 2010

Allergy or tolerance in children sensitized to peanut: prevalence and differentiation using component-resolved diagnostics.

J Allergy Clin Immunol 2010 Jan;125(1):191-7.e1-13

School of Translational Medicine, University of Manchester, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester M23 9LT, United Kingdom.

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January 2010