Angela M Carter

Angela M Carter

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Angela M Carter

Angela M Carter

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Complement and Cardiovascular Disease - The Missing Link in Haemodialysis Patients?

Nephron 2016 30;134(2):104. Epub 2016 Aug 30.

Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, Norfolk, UK.

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http://dx.doi.org/10.1159/000448741DOI Listing
October 2017

Complement and Cardiovascular Disease--The Missing Link in Haemodialysis Patients.

Nephron 2016 23;132(1):5-14. Epub 2015 Dec 23.

Department of Renal Medicine, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

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http://dx.doi.org/10.1159/000442426DOI Listing
October 2016

Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).

J Biol Chem 2014 Jul 22;289(28):19737-46. Epub 2014 May 22.

From the Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.564930
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http://dx.doi.org/10.1074/jbc.M114.564930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094083PMC
July 2014

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Authors:
Jie Huang Jennifer E Huffman Munekazu Yamakuchi Munekazu Yamkauchi Stella Trompet Folkert W Asselbergs Maria Sabater-Lleal David-Alexandre Trégouët Wei-Min Chen Nicholas L Smith Marcus E Kleber So-Youn Shin Diane M Becker Weihong Tang Abbas Dehghan Andrew D Johnson Vinh Truong Lasse Folkersen Qiong Yang Tiphaine Oudot-Mellkah Brendan M Buckley Jason H Moore Frances M K Williams Harry Campbell Günther Silbernagel Veronique Vitart Igor Rudan Geoffrey H Tofler Gerjan J Navis Anita Destefano Alan F Wright Ming-Huei Chen Anton J M de Craen Bradford B Worrall Alicja R Rudnicka Ann Rumley Ebony B Bookman Bruce M Psaty Fang Chen Keith L Keene Oscar H Franco Bernhard O Böhm Andre G Uitterlinden Angela M Carter J Wouter Jukema Naveed Sattar Joshua C Bis Mohammad A Ikram Michèle M Sale Barbara McKnight Myriam Fornage Ian Ford Kent Taylor P Eline Slagboom Wendy L McArdle Fang-Chi Hsu Anders Franco-Cereceda Alison H Goodall Lisa R Yanek Karen L Furie Mary Cushman Albert Hofman Jacqueline C M Witteman Aaron R Folsom Saonli Basu Nena Matijevic Wiek H van Gilst James F Wilson Rudi G J Westendorp Sekar Kathiresan Muredach P Reilly Russell P Tracy Ozren Polasek Bernhard R Winkelmann Peter J Grant Hans L Hillege Francois Cambien David J Stott Gordon D Lowe Timothy D Spector James B Meigs Winfried Marz Per Eriksson Lewis C Becker Pierre-Emmanuel Morange Nicole Soranzo Scott M Williams Caroline Hayward Pim van der Harst Anders Hamsten Charles J Lowenstein David P Strachan Christopher J O'Donnell

Arterioscler Thromb Vasc Biol 2014 May 27;34(5):1093-101. Epub 2014 Feb 27.

From National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (J.H., A.D.J., C.J.O.); Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, MD (J.H., A.D.J., C.J.O.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom (J.E.H., V.V., A.F.W., C.H.); The Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY (M.Y., C.J.L.); Departments of Cardiology (S.T., J.W.J.), Gerontology and Geriatrics (S.T., A.J.M.d.C., R.G.J.W.), and Molecular Epidemiology (P.E.S.), Leiden University Medical Center, the Netherlands; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (F.W.A.); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands (F.W.A.); Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom (F.W.A.); Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine (M.S.-L., L.F., P.E., A.H.), Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden; INSERM UMRS 937, Pierre et Marie Curie University, Paris, France (D.-A.T., V.T., T.O.M., F.C.); ICAN Institute for Cardiometabolism and Nutrion, Paris, France (D.-A.T., V.T., F.C.); Departments of Public Health Sciences (W.M.C., B.B.W., F.C.) and Biochemistry and Molecular Genetics (M.M.S.), Center for Public Health Genomics, University of Virginia, Charlottesville, VA; Departments of Epidemiology (N.L.S., B.M.P., B.M.), Medicine (B.M.P., J.C.B.), and Health Services (B.M.P.), University of Washington, Seattle, WA; Group Health Research Institute, Group Health Cooperative, Seattle, WA (N.L.S., B.M.P.); Seattle Epidemiologic Research and Information Center, VA Office of Research and

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http://dx.doi.org/10.1161/ATVBAHA.113.302088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009733PMC
May 2014

Adipose tissue inflammation: feeding the development of type 2 diabetes mellitus.

Immunobiology 2013 Dec 16;218(12):1497-504. Epub 2013 May 16.

Leeds Institute of Genetics Health & Therapeutics, Faculty of Medicine & Health and the Multidisciplinary Cardiovascular Research Centre, University of Leeds, UK.

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http://dx.doi.org/10.1016/j.imbio.2013.05.002DOI Listing
December 2013

Complement activation: an emerging player in the pathogenesis of cardiovascular disease.

Authors:
Angela M Carter

Scientifica (Cairo) 2012 16;2012:402783. Epub 2012 Dec 16.

Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, Faculty of Medicine and Health and the Multidisciplinary Cardiovascular Research Centre, University of Leeds, Clarendon Way, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.6064/2012/402783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820556PMC
November 2013

Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies.

Circulation 2013 Sep 4;128(13):1451-61. Epub 2013 Sep 4.

Departments of Neurology (C.C., O.S., C.G., T.M.), Experimental Neuropediatrics (C.C., M.S., D.I.), Department of Clinical Pharmacology and Toxicology (D.A., R.H.B., N.L., R.A.B., E.S.), and German Center for Cardiovascular Research (D.A., P.S.W., R.H.B., S.B., T.Z., E.S.), Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany (F.O., C.M., S. Baldus, S. Blankenberg, T.Z.); Department of Clinical Chemistry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (T.S.); Department of Cardiology and Angiology (P.S.W.), Gutenberg Health Study (P.S.W.), and Department of Clinical Chemistry (K.L.), Johannes Gutenberg University, Mainz, Germany; Experimental Neurophysiology, University Hospital Cologne, Köln, Germany (D.I.); German Center for Neurodegenerative Diseases, Bonn, Germany (D.I.); Department of Clinical Pharmacy and Pharmacotherapy, Martin-Luther-University Halle Wittenberg, Halle Germany (R.A.B.); Division of Cardiovascular and Diabetes Research, Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, UK (A.M.C., P.J.G.); Department of Radiology, Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands (C.N., A.H.); and Laboratory of Neurochemistry and Behavior, Born-Bunge Foundation, University of Antwerp, Antwerp, Belgium (B.M., P.P. De D.).

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http://circ.ahajournals.org/content/early/2013/09/04/CIRCULA
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http://circ.ahajournals.org/content/128/13/1451.full.pdf
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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.000580DOI Listing
September 2013

Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins.

J Biol Chem 2013 Apr 14;288(16):11325-33. Epub 2013 Mar 14.

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M113.450056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630898PMC
April 2013

Substrates of Factor XIII-A: roles in thrombosis and wound healing.

Clin Sci (Lond) 2013 Feb;124(3):123-37

Division of Cardiovascular & Diabetes Research, Leeds Institute for Genetics Health & Therapeutics, Faculty of Medicine & Health, and Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1042/CS20120233DOI Listing
February 2013

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Blood 2012 Dec 18;120(24):4873-81. Epub 2012 Sep 18.

National Heart, Lung, and Blood Institute (NHBLI) Framingham Heart Study, Framingham, MA 01702, USA.

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http://www.bloodjournal.org/content/120/24/4873.full.pdf
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http://atvb.ahajournals.org/content/34/5/1093.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-06-43
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http://dx.doi.org/10.1182/blood-2012-06-436188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520624PMC
December 2012

Complement C3 is a novel plasma clot component with anti-fibrinolytic properties.

Diab Vasc Dis Res 2012 Jul 17;9(3):216-25. Epub 2012 Jan 17.

Division of Cardiovascular & Diabetes Research, Leeds Institute of Genetics Health & Therapeutics, University of Leeds, UK.

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http://dx.doi.org/10.1177/1479164111432788DOI Listing
July 2012

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction.

Blood 2011 Jun 19;117(24):6694-701. Epub 2011 Apr 19.

Division of Cardiovascular & Diabetes Research, Section on Mechanisms of Thrombosis, Faculty of Medicine and Health, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1182/blood-2010-11-320325DOI Listing
June 2011

Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke.

Atherosclerosis 2010 Feb 23;208(2):518-23. Epub 2009 Jul 23.

Clinical Pharmacology Unit, Institute of Experimental and Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.06.039DOI Listing
February 2010

Role of proteomic technologies in understanding risk of arterial thrombosis.

Expert Rev Proteomics 2009 Oct;6(5):539-50

Division of Cardiovascular and Diabetes Research, Faculty of Medicine and Health, and the Multidisciplinary Cardiovacular Research Center, University of Leeds, UK.

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http://dx.doi.org/10.1586/epr.09.75DOI Listing
October 2009

Heritability of clot formation.

Semin Thromb Hemost 2009 Jul 8;35(5):458-67. Epub 2009 Sep 8.

Division of Cardiovascular and Diabetes Research, Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds LS29JT, United Kingdom.

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http://dx.doi.org/10.1055/s-0029-1234141DOI Listing
July 2009

Complement C3 and C-reactive protein in male survivors of myocardial infarction.

Atherosclerosis 2009 Apr 19;203(2):538-43. Epub 2008 Jul 19.

University of Leeds, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2008.07.007DOI Listing
April 2009

Identification of quantitative trait loci for fibrin clot phenotypes: the EuroCLOT study.

Arterioscler Thromb Vasc Biol 2009 Apr 15;29(4):600-5. Epub 2009 Jan 15.

Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1161/ATVBAHA.108.178103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508477PMC
April 2009

The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill.

J Renin Angiotensin Aldosterone Syst 2008 Dec;9(4):221-5

Proteolysis Research Group, Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.

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http://journals.sagepub.com/doi/10.1177/1470320308096405
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http://dx.doi.org/10.1177/1470320308096405DOI Listing
December 2008

Polymorphic variants of extracellular superoxide dismutase gene in a Romanian population with atheroma.

Biochem Genet 2008 Oct 26;46(9-10):634-43. Epub 2008 Aug 26.

Biochemistry Department, University of Medicine and Pharmacy "Victor Babes", Timisoara, Romania.

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http://dx.doi.org/10.1007/s10528-008-9177-3DOI Listing
October 2008

The application of proteomics technology to thrombosis research: the identification of potential therapeutic targets in cardiovascular disease.

Diab Vasc Dis Res 2008 Sep;5(3):205-12

Division of Cardiovascular & Diabetes Research, The LIGHT Laboratories, University of Leeds, LS2 9JT, UK.

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http://dx.doi.org/10.3132/dvdr.2008.033DOI Listing
September 2008

Regulation of Rho guanine nucleotide exchange factors by G proteins.

Adv Protein Chem 2007 ;74:189-228

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1016/S0065-3233(07)74006-8DOI Listing
June 2008

Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activity.

Atherosclerosis 2008 Jun 28;198(2):280-6. Epub 2007 Nov 28.

Academic Unit of Molecular Vascular Medicine, Leeds Institute for Genetics, Health and Therapeutics, University of Leeds, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587398PMC
June 2008

Identification, classification, and expression of RAGE gene splice variants.

FASEB J 2008 May 18;22(5):1572-80. Epub 2007 Dec 18.

Division of Surgical Science, Department of Surgery, College of Physicians and Surgeons, Columbia University, 630 W. 168th St., PS 17-401, New York, New York 10032, USA.

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http://dx.doi.org/10.1096/fj.07-9909comDOI Listing
May 2008

Does using nonnumerical terms to describe risk aid violence risk communication? Clinician agreement and decision making.

J Interpers Violence 2008 Feb;23(2):171-88

Mental Health Centre Penetanguishene, Ontario, Canada.

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http://dx.doi.org/10.1177/0886260507309337DOI Listing
February 2008

Heritability of clot formation, morphology, and lysis: the EuroCLOT study.

Arterioscler Thromb Vasc Biol 2007 Dec 11;27(12):2783-9. Epub 2007 Oct 11.

Academic Unit of Molecular Vascular Medicine, The LIGHT Laboratories, University of Leeds. Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1161/ATVBAHA.107.153221DOI Listing
December 2007

Functional analysis of fibrin {gamma}-chain cross-linking by activated factor XIII: determination of a cross-linking pattern that maximizes clot stiffness.

Blood 2007 Aug 13;110(3):902-7. Epub 2007 Apr 13.

Academic Unit of Molecular Vascular Medicine, Leeds Institute for Genetics, Health and Therapeutics, Clarendon Way, University of Leeds, UK.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-01-06
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http://dx.doi.org/10.1182/blood-2007-01-066837DOI Listing
August 2007

Predictive variables for mortality after acute ischemic stroke.

Stroke 2007 Jun 19;38(6):1873-80. Epub 2007 Apr 19.

Academic Unit of Molecular Vascular Medicine, The LIGHT Laboratories, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1161/STROKEAHA.106.474569DOI Listing
June 2007

Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study.

Hypertension 2006 Nov 25;48(5):914-20. Epub 2006 Sep 25.

Proteolysis Research Group, Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT United Kingdom.

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https://www.ahajournals.org/doi/10.1161/01.HYP.0000244543.91
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http://dx.doi.org/10.1161/01.HYP.0000244543.91937.79DOI Listing
November 2006

Complement C3 and C-reactive protein are elevated in South Asians independent of a family history of stroke.

Stroke 2006 Aug 29;37(8):2001-6. Epub 2006 Jun 29.

Academic Unit of Molecular Vascular Medicine, The LIGHT Laboratories, Clarendon Way, University of Leeds, Leeds, LS2 9JT. UK.

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http://stroke.ahajournals.org/content/37/8/2001.full.pdf
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http://stroke.ahajournals.org/cgi/doi/10.1161/01.STR.0000231
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http://dx.doi.org/10.1161/01.STR.0000231649.56080.6dDOI Listing
August 2006

Complement C3 and C-reactive protein levels in patients with stable coronary artery disease.

Thromb Haemost 2005 Nov;94(5):1048-53

Academic Unit of Molecular Vascular Medicine, Leeds Institute of Genetics Health and Therapeutics, Faculty of Medicine and Health, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1160/TH05-06-0384DOI Listing
November 2005

Inflammation, thrombosis and acute coronary syndromes.

Authors:
Angela M Carter

Diab Vasc Dis Res 2005 Oct;2(3):113-21

Academic Unit of Molecular Vascular Medicine, The LIGHT Laboratories, Clarendon Way, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.3132/dvdr.2005.018DOI Listing
October 2005

The application of proteomics to diabetes.

Diab Vasc Dis Res 2005 May;2(2):54-60

Academic Unit of Molecular Vascular Medicine, The LIGHT Laboratories, Clarendon Way, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.3132/dvdr.2005.009DOI Listing
May 2005

Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: effects on fibrin structure and function.

Circulation 2003 May 21;107(18):2326-30. Epub 2003 Apr 21.

Academic Unit of Molecular Vascular Medicine, Research School of Medicine, University of Leeds, Leeds General Infirmary, Leeds, UK.

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https://www.ahajournals.org/doi/10.1161/01.CIR.0000066690.89
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http://dx.doi.org/10.1161/01.CIR.0000066690.89407.CEDOI Listing
May 2003

Genetic regulation of fibrin structure and function: complex gene-environment interactions may modulate vascular risk.

Lancet 2003 Apr;361(9367):1424-31

Academic Unit of Molecular Vascular Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1016/S0140-6736(03)13135-2DOI Listing
April 2003

Increased fibrinogen levels among South Asians versus Whites in the United Kingdom are not explained by common polymorphisms.

Am J Epidemiol 2002 Jul;156(2):174-9

Unit of Molecular Vascular Medicine, Leeds General Infirmary, Leeds LS1 3EX, United Kingdom.

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http://dx.doi.org/10.1093/aje/kwf017DOI Listing
July 2002

Prothrombin G20210A is a bifunctional gene polymorphism.

Thromb Haemost 2002 May;87(5):846-53

Academic Unit of Molecular Vascular Medicine, University of Leeds, United Kingdom.

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May 2002