Publications by authors named "Angela Bachi"

100Publications

Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3.

Oncoimmunology 2020 May 21;9(1):1761205. Epub 2020 May 21.

Immunologie des Tumeurs et Immunothérapie, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2020.1761205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458623PMC
May 2020

SMfinder: Small Molecules Finder for Metabolomics and Lipidomics Analysis.

Anal Chem 2020 07 16;92(13):8874-8882. Epub 2020 Jun 16.

IFOM, The FIRC Institute of Molecular Oncology, 20139 Milan, Italy.

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http://dx.doi.org/10.1021/acs.analchem.0c00585DOI Listing
July 2020

Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness.

Sci Rep 2019 11 12;9(1):16640. Epub 2019 Nov 12.

IRCCS San Raffaele Scientific Institute, Molecular Basis of Cystic Kidney Disorders, Division of Genetics and Cell Biology, Milan, Italy.

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http://dx.doi.org/10.1038/s41598-019-53061-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851149PMC
November 2019

Metabolism of Stem and Progenitor Cells: Proper Methods to Answer Specific Questions.

Front Mol Neurosci 2019 13;12:151. Epub 2019 Jun 13.

Laboratory of Cell Metabolism and Regenerative Medicine, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.

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http://dx.doi.org/10.3389/fnmol.2019.00151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584756PMC
June 2019

Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain.

Biochim Biophys Acta Gen Subj 2019 02 19;1863(2):456-465. Epub 2018 Nov 19.

Biomolecular NMR Unit c/o IRCCS S. Raffaele, Via Olgettina 58, 20132 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2018.11.011DOI Listing
February 2019

STAGE-Diging in Proteomics.

Methods Mol Biol 2017 ;1654:255-260

IFOM, FIRC Institute of Molecular Oncology, Via Adamello 16, 20139, Milan, Italy.

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http://link.springer.com/10.1007/978-1-4939-7231-9_18
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http://dx.doi.org/10.1007/978-1-4939-7231-9_18DOI Listing
June 2018

Missing Value Monitoring Enhances the Robustness in Proteomics Quantitation.

J Proteome Res 2017 04 21;16(4):1719-1727. Epub 2017 Mar 21.

IFOM, the FIRC Institute of Molecular Oncology, Milan 20139, Italy.

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http://dx.doi.org/10.1021/acs.jproteome.6b01056DOI Listing
April 2017

24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development.

Proc Natl Acad Sci U S A 2016 10 26;113(41):E6219-E6227. Epub 2016 Sep 26.

Immuno-Biotherapy of Melanoma and Solid Tumors Unit, Division of Experimental Oncology, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Milan 20132, Italy;

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http://dx.doi.org/10.1073/pnas.1613332113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068323PMC
October 2016

Metabolic determinants of the immune modulatory function of neural stem cells.

J Neuroinflammation 2016 09 2;13(1):232. Epub 2016 Sep 2.

Department of Clinical Neurosciences, Wellcome Trust-Medical Research Council Stem Cell Institute and National Institute for Health Research Biomedical Research Centre, University of Cambridge, Hills Road, CB2 0HA, Cambridge, UK.

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http://dx.doi.org/10.1186/s12974-016-0667-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009670PMC
September 2016

DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach.

Nucleic Acids Res 2016 Oct 12;44(18):8786-8798. Epub 2016 Jul 12.

Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Ireland

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http://dx.doi.org/10.1093/nar/gkw626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062981PMC
October 2016

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression.

Nat Cell Biol 2016 06 25;18(6):684-91. Epub 2016 Apr 25.

DNA Metabolism Laboratory, IFOM, The FIRC Institute of Molecular Oncology, Via Adamello 16, Milan 20139, Italy.

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http://dx.doi.org/10.1038/ncb3344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939857PMC
June 2016

STAGE-diging: A novel in-gel digestion processing for proteomics samples.

J Proteomics 2016 05 6;140:48-54. Epub 2016 Apr 6.

IFOM, FIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2016.03.038DOI Listing
May 2016

Phosphoproteomic analysis of induced resistance reveals activation of signal transduction processes by beneficial and pathogenic interaction in grapevine.

J Plant Physiol 2016 May 14;195:59-72. Epub 2016 Mar 14.

Department of Sustainable Agro-ecosystems and Bioresources, Research and Innovation Centre, Fondazione Edmund Mach (FEM), Via E. Mach 1, 38010 San Michele all'Adige, Italy.

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http://dx.doi.org/10.1016/j.jplph.2016.03.007DOI Listing
May 2016

The Deubiquitinase USP9X Maintains DNA Replication Fork Stability and DNA Damage Checkpoint Responses by Regulating CLASPIN during S-Phase.

Cancer Res 2016 04 26;76(8):2384-93. Epub 2016 Feb 26.

Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2890DOI Listing
April 2016

Tenascin-C Protects Cancer Stem-like Cells from Immune Surveillance by Arresting T-cell Activation.

Cancer Res 2015 May 25;75(10):2095-108. Epub 2015 Mar 25.

Division of Immunology, Transplantation and Infectious Diseases, Cellular Immunology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2346DOI Listing
May 2015

SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity.

Hum Mol Genet 2015 Apr 1;24(7):1843-55. Epub 2014 Dec 1.

Dulbecco Telethon Institute at IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy,

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http://dx.doi.org/10.1093/hmg/ddu602DOI Listing
April 2015

Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells.

Mol Cell 2014 Oct 18;56(2):193-204. Epub 2014 Sep 18.

John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, and NIHR Biomedical Research Centre, University of Cambridge, CB2 0PY Cambridge, UK; Wellcome Trust-Medical Research Council Stem Cell Institute, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578249PMC
October 2014

Characterization of phosphorylation- and RNA-dependent UPF1 interactors by quantitative proteomics.

J Proteome Res 2014 Jun 6;13(6):3038-53. Epub 2014 May 6.

Department of Chemistry and Biochemistry, University of Bern , Freiestr. 3, Bern 3012, Switzerland.

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http://dx.doi.org/10.1021/pr5002143DOI Listing
June 2014

PA28αβ reduces size and increases hydrophilicity of 20S immunoproteasome peptide products.

Chem Biol 2014 Apr 13;21(4):470-480. Epub 2014 Mar 13.

Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2014.02.006DOI Listing
April 2014

Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1.

FEBS J 2014 Jan 25;281(1):216-31. Epub 2013 Nov 25.

Dulbecco Telethon Institute, c/o Biomolecular NMR Laboratory, S. Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1111/febs.12588DOI Listing
January 2014

Proteomics strategies to identify SUMO targets and acceptor sites: a survey of RNA-binding proteins SUMOylation.

Neuromolecular Med 2013 Dec 25;15(4):661-76. Epub 2013 Aug 25.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126, Milan, Italy.

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http://dx.doi.org/10.1007/s12017-013-8256-8DOI Listing
December 2013

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.

Pflugers Arch 2014 Feb 26;466(2):343-56. Epub 2013 Jul 26.

Institute of Physiology, ZIHP, University of Zurich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.

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http://dx.doi.org/10.1007/s00424-013-1321-1DOI Listing
February 2014

The stem cell secretome and its role in brain repair.

Biochimie 2013 Dec 1;95(12):2271-85. Epub 2013 Jul 1.

CNS Repair Unit, Institute of Experimental Neurology, Division of Neurosciences, San Raffaele Scientific Institute, 20132 Milan, Italy; Biomolecular Mass Spectrometry Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2013.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061727PMC
December 2013

Genomics and proteomics: how long do we need to reach clinical results?

Blood Purif 2013 25;36(1):7-11. Epub 2013 May 25.

Department of Internal Medicine, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1159/000350578DOI Listing
January 2014

Proteins from Tuber magnatum Pico fruiting bodies naturally grown in different areas of Italy.

Proteome Sci 2013 Feb 1;11(1). Epub 2013 Feb 1.

Department of Crop Plant Biology, University of Pisa, via Mariscoglio 34, 56124 Pisa, Italy.

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http://dx.doi.org/10.1186/1477-5956-11-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608153PMC
February 2013

Redox proteomics: chemical principles, methodological approaches and biological/biomedical promises.

Chem Rev 2013 Jan 26;113(1):596-698. Epub 2012 Nov 26.

Biological Mass Spectrometry Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.

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http://dx.doi.org/10.1021/cr300073pDOI Listing
January 2013

Attenuation of miR-126 activity expands HSC in vivo without exhaustion.

Cell Stem Cell 2012 Dec 8;11(6):799-811. Epub 2012 Nov 8.

Campbell Family Institute, Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.stem.2012.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517970PMC
December 2012

Proteomic analysis of grapevine resistance induced by Trichoderma harzianum T39 reveals specific defence pathways activated against downy mildew.

J Exp Bot 2012 Oct;63(17):6237-51

IASMA Research and Innovation Centre, Fondazione Edmund Mach, via E. Mach 1, 38010 San Michele all'Adige, Trento, Italy.

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http://dx.doi.org/10.1093/jxb/ers279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481215PMC
October 2012

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome.

Nucleic Acids Res 2012 Dec 15;40(22):11756-68. Epub 2012 Oct 15.

Biomolecular NMR Laboratory, Center of Translational Genomics and Bioinformatics, Dulbecco Telethon Institute c/o S. Raffaele Scientific Institute, Milano, Italy.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gks933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526288PMC
December 2012

Quantitative analysis of S-nitrosylated proteins.

Methods Mol Biol 2012 ;893:405-16

Mechanobiology Institute and Lipid Profiles, Centre for Life Sciences National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1007/978-1-61779-885-6_25DOI Listing
September 2012

Acclimation increases freezing stress response of Arabidopsis thaliana at proteome level.

Biochim Biophys Acta 2012 Jun 6;1824(6):813-25. Epub 2012 Apr 6.

Department of Crop Plant Biology, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1016/j.bbapap.2012.03.015DOI Listing
June 2012

Protein profiling reveals energy metabolism and cytoskeletal protein alterations in LMNA mutation carriers.

Biochim Biophys Acta 2012 Jun 3;1822(6):970-9. Epub 2012 Feb 3.

ProMiFa, Protein Microsequencing Facility, Division of Cell Biology and Genetics, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1016/j.bbadis.2012.01.014DOI Listing
June 2012

The role of bFGF on the ability of MSC to activate endogenous regenerative mechanisms in an ectopic bone formation model.

Biomaterials 2012 Mar 9;33(7):2086-96. Epub 2011 Dec 9.

Dept. of Oncology, Biology and Genetics, University of Genova, Largo Rosanna Benzi 10, 16132 Genova (GE), Italy.

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http://dx.doi.org/10.1016/j.biomaterials.2011.11.043DOI Listing
March 2012

Nanostructured TiO₂ thin films for phosphoproteomics studies with MALDI mass spectrometry.

Methods Mol Biol 2011 ;790:173-81

Division of Genetics & Cell Biology, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1007/978-1-61779-319-6_13DOI Listing
January 2012

Proteomic identification of differentially expressed proteins in the anoxic rice coleoptile.

J Plant Physiol 2011 Dec 13;168(18):2234-43. Epub 2011 Sep 13.

Plant Lab, Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy.

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http://dx.doi.org/10.1016/j.jplph.2011.07.009DOI Listing
December 2011

TACE (ADAM17) inhibits Schwann cell myelination.

Nat Neurosci 2011 Jun 12;14(7):857-65. Epub 2011 Jun 12.

Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.

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http://www.nature.com/articles/nn.2849
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http://dx.doi.org/10.1038/nn.2849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291894PMC
June 2011

Fabry disease: perspectives of urinary proteomics.

J Nephrol 2010 Nov-Dec;23 Suppl 16:S199-212

Department of Internal Medicine, Second University of Naples, Naples, Italy.

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February 2011

Catalytic properties of the retinal rod outer segment disk ADP-ribosyl cyclase.

Vis Neurosci 2011 Mar 27;28(2):121-8. Epub 2011 Jan 27.

Department of Biology, University of Genoa, Genova, Italy.

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http://dx.doi.org/10.1017/S0952523810000404DOI Listing
March 2011

Popeye strikes again: The deep proteome of spinach leaves.

J Proteomics 2011 Jan 5;74(1):127-36. Epub 2010 Nov 5.

Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, 20131 Milan, Italy.

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http://dx.doi.org/10.1016/j.jprot.2010.10.009DOI Listing
January 2011

P0 (protein zero) mutation S34C underlies instability of internodal myelin in S63C mice.

J Biol Chem 2010 Dec 11;285(53):42001-12. Epub 2010 Oct 11.

Biology Department, Boston College, Chestnut Hill, Massachusetts 02467-3811, USA.

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http://dx.doi.org/10.1074/jbc.M110.166967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009926PMC
December 2010

Noah's nectar: the proteome content of a glass of red wine.

J Proteomics 2010 Nov 8;73(12):2370-7. Epub 2010 Sep 8.

Department of Chemistry, Materials and Chemical Engineering Giulio Natta, Politecnico di Milano, Via Mancinelli 7, 20131 Milano, Italy.

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http://dx.doi.org/10.1016/j.jprot.2010.08.010DOI Listing
November 2010

HS1 has a central role in the trafficking and homing of leukemic B cells.

Blood 2010 Nov 8;116(18):3537-46. Epub 2010 Jun 8.

Unit of Lymphoid Malignancies, Division of Molecular Oncology, San Raffaele Scientific Institute, Via Olgettina 58, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2009-12-258814DOI Listing
November 2010

Direct and indirect detection methods for the analysis of S-nitrosylated peptides and proteins.

Methods Enzymol 2010 ;473:265-80

Biomolecular Mass Spectrometry Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1016/S0076-6879(10)73014-7DOI Listing
September 2010

Proteomics of wine additives: mining for the invisible via combinatorial peptide ligand libraries.

J Proteomics 2010 Aug 25;73(9):1732-9. Epub 2010 May 25.

Department of Chemistry, Materials and Chemical Engineering Giulio Natta, Politecnico di Milano, Via Mancinelli 7, 20131 Milano, Italy.

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http://dx.doi.org/10.1016/j.jprot.2010.05.010DOI Listing
August 2010

Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers.

Antimicrob Agents Chemother 2010 Jul 17;54(7):2994-3001. Epub 2010 May 17.

Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, 20132 Milan, Italy.

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http://aac.asm.org/cgi/doi/10.1128/AAC.01492-09
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http://dx.doi.org/10.1128/AAC.01492-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897324PMC
July 2010

In depth exploration of the hemolymph of Limulus polyphemus via combinatorial peptide ligand libraries.

J Proteome Res 2010 Jun;9(6):3260-9

San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1021/pr1002033DOI Listing
June 2010

The CD4+ T-cell epitope-binding register is a critical parameter when generating functional HLA-DR tetramers with promiscuous peptides.

Eur J Immunol 2010 Jun;40(6):1603-16

Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.

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http://dx.doi.org/10.1002/eji.200940123DOI Listing
June 2010

In-depth exploration of Hevea brasiliensis latex proteome and "hidden allergens" via combinatorial peptide ligand libraries.

J Proteomics 2010 May 11;73(7):1368-80. Epub 2010 Mar 11.

Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy.

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http://dx.doi.org/10.1016/j.jprot.2010.03.002DOI Listing
May 2010

Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.

Cell Mol Life Sci 2010 Jun 9;67(12):2107-18. Epub 2010 Mar 9.

Division of Molecular Oncology and IIT Network Research Unit of Molecular Neuroscience, San Raffaele Scientific Institute, via Olgettina 58, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00018-010-0319-5DOI Listing
June 2010

Comparison of different depletion strategies for improving resolution of the human urine proteome.

Clin Chem Lab Med 2010 Apr;48(4):531-5

Center for Genomics, Bioinformatics and Biostatistics, Genomics Unit for Human Disease Diagnosis, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1515/CCLM.2010.109DOI Listing
April 2010

The highly conserved synapsin domain E mediates synapsin dimerization and phospholipid vesicle clustering.

Biochem J 2010 Jan 27;426(1):55-64. Epub 2010 Jan 27.

Department of Experimental Medicine, University of Genoa, 16132 Genoa, Italy.

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http://dx.doi.org/10.1042/BJ20090762DOI Listing
January 2010

Titanium dioxide coated MALDI plate for on target analysis of phosphopeptides.

J Proteome Res 2009 Apr;8(4):1932-42

Biological Mass Spectrometry Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milano, Italy.

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http://dx.doi.org/10.1021/pr8008836DOI Listing
April 2009

Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.

Mol Cell Proteomics 2009 Oct 12;8(10):2243-55. Epub 2009 Jul 12.

Division of Genomics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1074/mcp.M900079-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758753PMC
October 2009

Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration.

PLoS One 2009 Jun 18;4(6):e5968. Epub 2009 Jun 18.

Scuola Internazionale Superiore di Studi Avanzati-International School for Advanced Studies (SISSA-ISAS); Italian Institute of Technology, [corrected] Trieste, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005968PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693666PMC
June 2009

Collagenase isoforms for pancreas digestion.

Cell Transplant 2009 ;18(2):203-6

Unit of Cell Therapy for Type 1 Diabetes Mellitus, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.3727/096368909788341270DOI Listing
August 2009

Searching for specific motifs in affinity capture in proteome analysis.

J Proteomics 2009 Jul 16;72(5):791-802. Epub 2009 Apr 16.

Department of Electronics and Informatics, Politecnico di Milano, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.jprot.2009.04.001DOI Listing
July 2009

Channel-interacting PDZ protein, 'CIPP', interacts with proteins involved in cytoskeletal dynamics.

Biochem J 2009 Apr;419(2):289-300

Cell and Developmental Biology Laboratory, Department of Biology, University of Pisa, 56010 Pisa, Italy.

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http://dx.doi.org/10.1042/BJ20081387DOI Listing
April 2009