Publications by authors named "Aneta Stachurska"

3 Publications

  • Page 1 of 1

Parameters of Oxidative and Inflammatory Status in a Three-Month Observation of Patients with Acute Myocardial Infarction Undergoing Coronary Angioplasty-A Preliminary Study.

Medicina (Kaunas) 2019 Sep 13;55(9). Epub 2019 Sep 13.

Department of Toxicology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

: Patients with acute myocardial infarction (MI) are usually treated with percutaneous transluminal coronary angioplasty (PTCA), which is burdened with a risk of postoperative complications, often accompanied by biochemical disturbances. The aim of our study was to evaluate a set of selected parameters of oxidative and inflammatory status, which could be useful in the management of post-procedural care in MI patients after PTCA. : In this preliminary study, ischemia modified albumin (IMA), advanced oxidation protein products (AOPP), thiol groups (SH), total antioxidant status (TAS), insulin growth factor-1 (IGF-1), presepsin (PSP), and trimethylamine N-oxide (TMAO) were chosen as candidate biomarkers, and were determined in patients with MI who underwent PTCA at two time points: During cardiac episodes (at admission to the hospital, T0) and 3 months later (T3). : Most of the examined parameters were significantly different between patients and control subjects (except for IMA and TAS), but only hsCRP changed significantly during the time of observation (T0 vs. T3). Discriminant analysis created a model composed of AOPP, hsCRP, PSP, and TMAO, which differentiated male subjects into a group with MI and a control (without cardiovascular diseases). : This set of parameters seems useful in evaluating inflammatory and oxidative status in MI patients after PTCA.
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http://dx.doi.org/10.3390/medicina55090585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780791PMC
September 2019

Parameters of Oxidative and Inflammatory Status in a Three-Month Observation of Patients with Acute Myocardial Infarction Undergoing Coronary Angioplasty-A Preliminary Study.

Medicina (Kaunas) 2019 Sep 13;55(9). Epub 2019 Sep 13.

Department of Toxicology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

: Patients with acute myocardial infarction (MI) are usually treated with percutaneous transluminal coronary angioplasty (PTCA), which is burdened with a risk of postoperative complications, often accompanied by biochemical disturbances. The aim of our study was to evaluate a set of selected parameters of oxidative and inflammatory status, which could be useful in the management of post-procedural care in MI patients after PTCA. : In this preliminary study, ischemia modified albumin (IMA), advanced oxidation protein products (AOPP), thiol groups (SH), total antioxidant status (TAS), insulin growth factor-1 (IGF-1), presepsin (PSP), and trimethylamine N-oxide (TMAO) were chosen as candidate biomarkers, and were determined in patients with MI who underwent PTCA at two time points: During cardiac episodes (at admission to the hospital, T0) and 3 months later (T3). : Most of the examined parameters were significantly different between patients and control subjects (except for IMA and TAS), but only hsCRP changed significantly during the time of observation (T0 vs. T3). Discriminant analysis created a model composed of AOPP, hsCRP, PSP, and TMAO, which differentiated male subjects into a group with MI and a control (without cardiovascular diseases). : This set of parameters seems useful in evaluating inflammatory and oxidative status in MI patients after PTCA.
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http://dx.doi.org/10.3390/medicina55090585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780791PMC
September 2019

[Attempt to objectify of coronary vessels course variability on the standard arteriograms by using original image processing algorithm].

Wiad Lek 2014 ;67(1):28-32

The aim of paper: the analysis of standard angiograms of the left coronary artery was done in this paper in purpose of performing the uniform mathematical description of the coronary branches (both proximal and distal) course. The changes the coronary branches underwent depending the phase of cardiac cycle (diastole, isovolumic systole and tonic systole) were examined as well. The examined material consists of sequences of standard angiograms of the left coronary artery (LCA) obtained from 10 patients (5 male and 5 female) undergoing the standard diagnostic procedure in course of suspected unstable cardiac ischemia. The coronarograms were applied with digital angiography system INNOVA 2000 GE. The average age of the patients was 51 years. The method was based on using the original algorithm of image processing allowing automatic, in real-time, vessel edges detection and mathematical description of the vessels course. The software ImageJ, deriving from public domain of National Institutes of Health of USA was used for image analysis and for statistical analysis Statistica for Windows 5.5 version. The obtained results of examined dependences and describing them mathematically polynomial equations were presented on the diagrams. Among examined parameters the ferret diameter, area and perimeter of vessel outlines (both proximal and distal branches) were the most reliable. Their changes in relation to the phase of cardiac cycle were very close to the level of statistical significance. In conclusion the performed analysis allows to objectify description of coronary vessels course and variability. It also makes possible to identify the abnormal manners of vessels outlines that could be suspected of structural disorders even despite the absence of significant coronary stenosis.
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April 2015
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