Publications by authors named "Andy Shih"

64Publications

Mild pericyte deficiency is associated with aberrant brain microvascular flow in aged PDGFRβ mice.

J Cereb Blood Flow Metab 2020 Jan 27:271678X19900543. Epub 2020 Jan 27.

Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0271678X19900543DOI Listing
January 2020

In vivo two-photon imaging of neuronal and brain vascular responses in mice chronically exposed to ethanol.

Alcohol 2020 06 17;85:41-47. Epub 2019 Dec 17.

Department of Neuroscience, Medical University of South Carolina, Charleston, SC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.alcohol.2019.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237312PMC
June 2020

Postnatal development of cerebrovascular structure and the neurogliovascular unit.

Wiley Interdiscip Rev Dev Biol 2020 03 1;9(2):e363. Epub 2019 Oct 1.

Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington.

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http://dx.doi.org/10.1002/wdev.363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027551PMC
March 2020

Combining serial block face and focused ion beam scanning electron microscopy for 3D studies of rare events.

Methods Cell Biol 2019 7;152:87-101. Epub 2019 May 7.

VIB BioImaging Core, VIB, Ghent, Belgium; VIB Inflammation Research Center, VIB, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/bs.mcb.2019.03.014DOI Listing
April 2020

Sharpening the tools for pericyte research.

Nat Neurosci 2019 07;22(7):1041-1043

Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41593-019-0437-9DOI Listing
July 2019

Health Disparities among Children with Autism Spectrum Disorders: Analysis of the National Survey of Children's Health 2016.

J Autism Dev Disord 2019 Apr;49(4):1652-1664

Autism Speaks, 1060 State Rd, Princeton, NJ, USA.

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http://dx.doi.org/10.1007/s10803-018-3862-9DOI Listing
April 2019

Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis.

Front Aging Neurosci 2018 17;10:210. Epub 2018 Jul 17.

Department of Neuroscience, Medical University of South Carolina, Charleston, SC, United States.

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http://dx.doi.org/10.3389/fnagi.2018.00210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057109PMC
July 2018

Rodent Models of Cerebral Microinfarct and Microhemorrhage.

Stroke 2018 03 19;49(3):803-810. Epub 2018 Feb 19.

From the Department of Neuroscience (A.Y.S., D.A.H.) and Center for Biomedical Imaging (A.Y.S.), Medical University of South Carolina, Charleston, SC; Aflac Cancer and Blood Disorder Center, Children's Healthcare of Atlanta and Emory University Department of Pediatrics, GA (H.I.H.); and Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (S.J.v.V.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851653PMC
March 2018

Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain.

Cell Rep 2018 01;22(1):8-16

Department of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782812PMC
January 2018

Entrainment of Arteriole Vasomotor Fluctuations by Neural Activity Is a Basis of Blood-Oxygenation-Level-Dependent "Resting-State" Connectivity.

Neuron 2017 Nov 26;96(4):936-948.e3. Epub 2017 Oct 26.

Department of Physics, University of California, San Diego, La Jolla, CA, USA; Section of Neurobiology, University of California, San Diego, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851777PMC
November 2017

Does pathology of small venules contribute to cerebral microinfarcts and dementia?

J Neurochem 2018 03 7;144(5):517-526. Epub 2017 Nov 7.

Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1111/jnc.14228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869083PMC
March 2018

Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex.

J Cereb Blood Flow Metab 2019 03 21;39(3):411-425. Epub 2017 Sep 21.

1 Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0271678X17732229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399730PMC
March 2019

Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease.

J Cereb Blood Flow Metab 2019 02 19;39(2):342-351. Epub 2017 Sep 19.

4 Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0271678X17732275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365608PMC
February 2019

Photothrombotic Induction of Capillary Ischemia in the Mouse Cortex during Two-photon Imaging.

Bio Protoc 2017 Jul;7(13)

Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.21769/BioProtoc.2378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565166PMC
July 2017

Detection, risk factors, and functional consequences of cerebral microinfarcts.

Lancet Neurol 2017 09 14;16(9):730-740. Epub 2017 Jul 14.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30196-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861500PMC
September 2017

Autism in Southeast Europe: A Survey of Caregivers of Children with Autism Spectrum Disorders.

J Autism Dev Disord 2017 08;47(8):2314-2325

Autism Speaks, 1 E, 33rd street, New York, NY, 10016, USA.

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http://dx.doi.org/10.1007/s10803-017-3145-xDOI Listing
August 2017

Functional deficits induced by cortical microinfarcts.

J Cereb Blood Flow Metab 2017 Nov 16;37(11):3599-3614. Epub 2017 Jan 16.

1 Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1177/0271678X16685573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669342PMC
November 2017

Microvascular basis for growth of small infarcts following occlusion of single penetrating arterioles in mouse cortex.

J Cereb Blood Flow Metab 2016 08 13;36(8):1357-73. Epub 2015 Oct 13.

Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, USA

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http://dx.doi.org/10.1177/0271678X15608388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976746PMC
August 2016

Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice.

Neurophotonics 2015 Oct 27;2(4):041402. Epub 2015 May 27.

Medical University of South Carolina , Department of Neurosciences, 173 Ashley Avenue CRI 406, Charleston, South Carolina 29425, United States ; Medical University of South Carolina , Center for Biomedical Imaging, 68 President Street, Charleston, South Carolina 29425, United States.

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http://neurophotonics.spiedigitallibrary.org/article.aspx?do
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http://dx.doi.org/10.1117/1.NPh.2.4.041402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478963PMC
October 2015

A murine toolbox for imaging the neurovascular unit.

Microcirculation 2015 Apr;22(3):168-82

Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1111/micc.12176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393760PMC
April 2015

Approaches to enhancing the early detection of autism spectrum disorders: a systematic review of the literature.

J Am Acad Child Adolesc Psychiatry 2014 Feb 19;53(2):141-52. Epub 2013 Nov 19.

Duke University School of Medicine.

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http://dx.doi.org/10.1016/j.jaac.2013.11.002DOI Listing
February 2014

Targeted Occlusion of Individual Pial Vessels of Mouse Cortex.

Bio Protoc 2013 Sep;3(17)

Department of Neurosciences, Medical University of South Carolina, Charleston, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991877PMC
http://dx.doi.org/10.21769/bioprotoc.897DOI Listing
September 2013

Two-photon imaging of blood flow in the rat cortex.

Cold Spring Harb Protoc 2013 Aug 1;2013(8):759-67. Epub 2013 Aug 1.

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http://dx.doi.org/10.1101/pdb.prot076513DOI Listing
August 2013

The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit.

Nat Neurosci 2013 Jan 16;16(1):55-63. Epub 2012 Dec 16.

Department of Physics, University of California at San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nn.3278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952571PMC
January 2013

A global public health strategy for autism spectrum disorders.

Autism Res 2012 Jun 17;5(3):211-7. Epub 2012 May 17.

Autism Speaks, 1 East 33rd Street, New York, NY 10016, USA.

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http://dx.doi.org/10.1002/aur.1236DOI Listing
June 2012

A polished and reinforced thinned-skull window for long-term imaging of the mouse brain.

J Vis Exp 2012 Mar 7(61). Epub 2012 Mar 7.

Department of Physics, University of California-San Diego, CA, USA.

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http://dx.doi.org/10.3791/3742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460568PMC
March 2012

Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain.

J Cereb Blood Flow Metab 2012 Jul 1;32(7):1277-309. Epub 2012 Feb 1.

Department of Physics, University of California at San Diego, La Jolla, CA 92093-0374, USA.

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http://dx.doi.org/10.1038/jcbfm.2011.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390800PMC
July 2012

A guide to delineate the logic of neurovascular signaling in the brain.

Front Neuroenergetics 2011 25;3. Epub 2011 Apr 25.

Department of Physics, University of California San Diego La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fnene.2011.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085135PMC
July 2011

Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity.

Proc Natl Acad Sci U S A 2011 May 2;108(20):8473-8. Epub 2011 May 2.

Departments of Physics and Neurobiology and Center for Neural Circuits and Behavior, University of California, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1073/pnas.1100428108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100929PMC
May 2011

Photon counting, censor corrections, and lifetime imaging for improved detection in two-photon microscopy.

J Neurophysiol 2011 Jun 6;105(6):3106-13. Epub 2011 Apr 6.

Department of Physics, University of California at San Diego, La Jolla, CA 92093-0374, USA.

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http://dx.doi.org/10.1152/jn.00649.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118755PMC
June 2011

Chronic optical access through a polished and reinforced thinned skull.

Nat Methods 2010 Dec 21;7(12):981-4. Epub 2010 Oct 21.

Department of Physics, University of California at San Diego, San Diego, California, USA.

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http://dx.doi.org/10.1038/nmeth.1530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204312PMC
December 2010

Topological basis for the robust distribution of blood to rodent neocortex.

Proc Natl Acad Sci U S A 2010 Jul 28;107(28):12670-5. Epub 2010 Jun 28.

Department of Physics, Division of Biology, Graduate Program in Neurosciences, and Center for Neural Circuits and Behavior, University of California, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1073/pnas.1007239107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906564PMC
July 2010

Automatic identification of fluorescently labeled brain cells for rapid functional imaging.

J Neurophysiol 2010 Sep 7;104(3):1803-11. Epub 2010 Jul 7.

Dept. of Physics 0374, Univ. of California, 9500 Gilman Dr., La Jolla, CA 92093-0374, USA.

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http://dx.doi.org/10.1152/jn.00484.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944673PMC
September 2010

Highly stable resistive switching on monocrystalline ZnO.

Nanotechnology 2010 Mar 25;21(12):125201. Epub 2010 Feb 25.

Department of Electrical and Computer Engineering, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1088/0957-4484/21/12/125201DOI Listing
March 2010

Autism Speaks Global Autism Public Health Initiative: Bridging gaps in autism awareness, research, and services around the world.

Beijing Da Xue Xue Bao Yi Xue Ban 2009 Aug;41(4):389-91

Autism Speaks, New York, NY 10016, USA.

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August 2009

Rapid determination of particle velocity from space-time images using the Radon transform.

J Comput Neurosci 2010 Aug 21;29(1-2):5-11. Epub 2009 May 21.

Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1007/s10827-009-0159-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962871PMC
August 2010

Acute vascular disruption and aquaporin 4 loss after stroke.

Stroke 2009 Jun 16;40(6):2182-90. Epub 2009 Apr 16.

Department of Neurosciences, UCSD School of Medicine, San Diego, CA, USA.

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http://dx.doi.org/10.1161/STROKEAHA.108.523720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753985PMC
June 2009

Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke.

J Cereb Blood Flow Metab 2009 Apr 28;29(4):738-51. Epub 2009 Jan 28.

Department of Physics, University of California at San Diego, La Jolla, California 92093-0374, USA.

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http://dx.doi.org/10.1038/jcbfm.2008.166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893883PMC
April 2009

Dopamine activates Nrf2-regulated neuroprotective pathways in astrocytes and meningeal cells.

J Neurochem 2007 Apr 12;101(1):109-19. Epub 2007 Jan 12.

Kinsmen Laboratory of Neurological Research, Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/j.1471-4159.2006.04345.xDOI Listing
April 2007

Mapping autism risk loci using genetic linkage and chromosomal rearrangements.

Authors:
Peter Szatmari Andrew D Paterson Lonnie Zwaigenbaum Wendy Roberts Jessica Brian Xiao-Qing Liu John B Vincent Jennifer L Skaug Ann P Thompson Lili Senman Lars Feuk Cheng Qian Susan E Bryson Marshall B Jones Christian R Marshall Stephen W Scherer Veronica J Vieland Christopher Bartlett La Vonne Mangin Rhinda Goedken Alberto Segre Margaret A Pericak-Vance Michael L Cuccaro John R Gilbert Harry H Wright Ruth K Abramson Catalina Betancur Thomas Bourgeron Christopher Gillberg Marion Leboyer Joseph D Buxbaum Kenneth L Davis Eric Hollander Jeremy M Silverman Joachim Hallmayer Linda Lotspeich James S Sutcliffe Jonathan L Haines Susan E Folstein Joseph Piven Thomas H Wassink Val Sheffield Daniel H Geschwind Maja Bucan W Ted Brown Rita M Cantor John N Constantino T Conrad Gilliam Martha Herbert Clara Lajonchere David H Ledbetter Christa Lese-Martin Janet Miller Stan Nelson Carol A Samango-Sprouse Sarah Spence Matthew State Rudolph E Tanzi Hilary Coon Geraldine Dawson Bernie Devlin Annette Estes Pamela Flodman Lambertus Klei William M McMahon Nancy Minshew Jeff Munson Elena Korvatska Patricia M Rodier Gerard D Schellenberg Moyra Smith M Anne Spence Chris Stodgell Ping Guo Tepper Ellen M Wijsman Chang-En Yu Bernadette Rogé Carine Mantoulan Kerstin Wittemeyer Annemarie Poustka Bärbel Felder Sabine M Klauck Claudia Schuster Fritz Poustka Sven Bölte Sabine Feineis-Matthews Evelyn Herbrecht Gabi Schmötzer John Tsiantis Katerina Papanikolaou Elena Maestrini Elena Bacchelli Francesca Blasi Simona Carone Claudio Toma Herman Van Engeland Maretha de Jonge Chantal Kemner Frederieke Koop Frederike Koop Marjolein Langemeijer Marjolijn Langemeijer Channa Hijmans Channa Hijimans Wouter G Staal Gillian Baird Patrick F Bolton Michael L Rutter Emma Weisblatt Jonathan Green Catherine Aldred Julie-Anne Wilkinson Andrew Pickles Ann Le Couteur Tom Berney Helen McConachie Anthony J Bailey Kostas Francis Gemma Honeyman Aislinn Hutchinson Jeremy R Parr Simon Wallace Anthony P Monaco Gabrielle Barnby Kazuhiro Kobayashi Janine A Lamb Ines Sousa Nuala Sykes Edwin H Cook Stephen J Guter Bennett L Leventhal Jeff Salt Catherine Lord Christina Corsello Vanessa Hus Daniel E Weeks Fred Volkmar Maïté Tauber Eric Fombonne Andy Shih Kacie J Meyer

Nat Genet 2007 Mar 18;39(3):319-28. Epub 2007 Feb 18.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.

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http://dx.doi.org/10.1038/ng1985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867008PMC
March 2007

Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity.

Brain Res 2007 Jan 17;1127(1):26-35. Epub 2006 Nov 17.

Department of Neurosciences, Medical University of South Carolina, 173 Ashley Avenue, BSB 403C, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.10.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831835PMC
January 2007

Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.

J Neurosci 2006 Oct;26(41):10514-23

Kinsmen Laboratory of Neurological Research and Brain Research Center, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3.

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http://dx.doi.org/10.1523/JNEUROSCI.3178-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674710PMC
October 2006

Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface.

J Biol Chem 2006 Jun 19;281(25):17420-31. Epub 2006 Apr 19.

Department of Psychiatry, Kinsmen Laboratory of Neurological Research and Brain Research Centre, University of British Columbia, Vancouver V6T 1Z3, British Columbia, Canada.

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http://dx.doi.org/10.1074/jbc.M601567200DOI Listing
June 2006

Policing the police: astrocytes modulate microglial activation.

J Neurosci 2006 Apr;26(15):3887-8

Graduate Program in Neuroscience, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.

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http://dx.doi.org/10.1523/JNEUROSCI.0936-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673885PMC
April 2006

A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

J Neurosci 2005 Nov;25(44):10321-35

Department of Psychiatry, Kinsmen Laboratory of Neurological Research and Brain Research Center, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.

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http://dx.doi.org/10.1523/JNEUROSCI.4014-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725780PMC
November 2005

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

J Biol Chem 2005 Jun 19;280(24):22925-36. Epub 2005 Apr 19.

Kinsmen Laboratory, Department of Psychiatry, Brain Research Center, Vancouver, Canada.

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http://dx.doi.org/10.1074/jbc.M414635200DOI Listing
June 2005

NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons.

J Biol Chem 2003 Sep 3;278(39):37948-56. Epub 2003 Jul 3.

School of Pharmacy, University of Wisconsin, Madison 53705-2222, USA.

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http://dx.doi.org/10.1074/jbc.M305204200DOI Listing
September 2003

Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress.

J Neurosci 2003 Apr;23(8):3394-406

Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742304PMC
April 2003