Andy Ryan

Andy Ryan

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Andy Ryan

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Serial endometrial thickness and risk of non-endometrial hormone-dependent cancers in postmenopausal women in UKCTOCS.

Ultrasound Obstet Gynecol 2019 Oct 15. Epub 2019 Oct 15.

MRC CTU, Institute of Clinical Trials and Methodology, University College London, UK.

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http://dx.doi.org/10.1002/uog.21894DOI Listing
October 2019

Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel.

Br J Cancer 2019 Sep 7;121(6):483-489. Epub 2019 Aug 7.

School of Biological Sciences, Queens University Belfast, Chlorine Gardens, Belfast, BT9 5DL, UK.

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http://dx.doi.org/10.1038/s41416-019-0544-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738042PMC
September 2019

Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study.

Lancet Oncol 2019 Aug 9;20(8):1171-1182. Epub 2019 Jul 9.

Department of Women's Cancer, EGA Institute for Women's Health, Faculty of Population Health Sciences, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30340-7DOI Listing
August 2019

Serum HE4 and diagnosis of ovarian cancer in postmenopausal women with adnexal masses.

Am J Obstet Gynecol 2019 Jul 24. Epub 2019 Jul 24.

Medical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, University College London, London. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2019.07.031DOI Listing
July 2019

A quantitative performance study of two automatic methods for the diagnosis of ovarian cancer.

Biomed Signal Process Control 2018 Sep;46:86-93

Department of Women's Cancer, Institute for Women's Health, University College London, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1016/j.bspc.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146655PMC
September 2018

Pleural abnormalities and exposure to elongate mineral particles in Minnesota iron ore (taconite) workers.

Am J Ind Med 2018 05 8;61(5):391-399. Epub 2018 Mar 8.

Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/ajim.22828DOI Listing
May 2018

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

Authors:
Ellen L Goode Matthew S Block Kimberly R Kalli Robert A Vierkant Wenqian Chen Zachary C Fogarty Aleksandra Gentry-Maharaj Aleksandra Tołoczko Alexander Hein Aliecia L Bouligny Allan Jensen Ana Osorio Andreas Hartkopf Andy Ryan Anita Chudecka-Głaz Anthony M Magliocco Arndt Hartmann Audrey Y Jung Bo Gao Brenda Y Hernandez Brooke L Fridley Bryan M McCauley Catherine J Kennedy Chen Wang Chloe Karpinskyj Christiani B de Sousa Daniel G Tiezzi David L Wachter Esther Herpel Florin Andrei Taran Francesmary Modugno Gregg Nelson Jan Lubiński Janusz Menkiszak Jennifer Alsop Jenny Lester Jesús García-Donas Jill Nation Jillian Hung José Palacios Joseph H Rothstein Joseph L Kelley Jurandyr M de Andrade Luis Robles-Díaz Maria P Intermaggio Martin Widschwendter Matthias W Beckmann Matthias Ruebner Mercedes Jimenez-Linan Naveena Singh Oleg Oszurek Paul R Harnett Peter F Rambau Peter Sinn Philipp Wagner Prafull Ghatage Raghwa Sharma Robert P Edwards Roberta B Ness Sandra Orsulic Sara Y Brucker Sharon E Johnatty Teri A Longacre Eilber Ursula Valerie McGuire Weiva Sieh Yanina Natanzon Zheng Li Alice S Whittemore deFazio Anna Annette Staebler Beth Y Karlan Blake Gilks David D Bowtell Estrid Høgdall Francisco J Candido dos Reis Helen Steed Ian G Campbell Jacek Gronwald Javier Benítez Jennifer M Koziak Jenny Chang-Claude Kirsten B Moysich Linda E Kelemen Linda S Cook Marc T Goodman María José García Peter A Fasching Stefan Kommoss Suha Deen Susanne K Kjaer Usha Menon James D Brenton Paul DP Pharoah Georgia Chenevix-Trench David G Huntsman Stacey J Winham Martin Köbel Susan J Ramus

JAMA Oncol 2017 12;3(12):e173290

School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia

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http://dx.doi.org/10.1001/jamaoncol.2017.3290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744673PMC
December 2017

A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours.

Br J Cancer 2017 Aug 29;117(5):666-674. Epub 2017 Jun 29.

Stoller Biomarker Discovery Centre and Pathology Node, Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/bjc.2017.199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572165PMC
August 2017

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

Circulation 2017 Jun 12;135(24):2373-2388. Epub 2017 May 12.

From Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, United Kingdom (C.E.D., G.F., D.P.-M., A.D.H., J.P.C.); Department of Mathematics and Statistics, Lancaster University, United Kingdom (T.M.P.); UCLGenetics Institute, University College London, United Kingdom (J.W.); Applied Statistical Methods in Medical Research Group, Universidad Catolica de San Antonio de Murcia, Spain (D.P.-M.); Social Genetic & Developmental Psychiatry, King's College London, United Kingdom (D.Z.); Institute of Cardiovascular Science, University College London, United Kingdom (J.E.L.E., T.S., A.D.H., S.E.H.); MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom (A.W., D.K.); Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (S.M., J.F.P.); Department of Cardiology, Leiden University Medical Center, The Netherlands (S.T., W.J.); South Australian Health and Medical Research Institute, Adelaide (M.M., E.H.); EMBL Australia, Adelaide (M.M.); School of Social and Community Medicine, University of Bristol, United Kingdom (R.W.M., T.R.G., Y.B.-S., D.A.L., G.D.S.); Centre for Clinical Pharmacology, University College London, United Kingdom (R.S.); Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom (M.K.); Centre for Population Health Research, School of Health Sciences and Sansom Institute, University of South Australia, Adelaide (E.H., A.Z.); Population, Policy & Practice, UCL Great Ormond Street Institute of Child Health, London, United Kingdom (E.H., C.P.); Department of Primary Care & Population Health, University College London, Royal Free Campus, United Kingdom (B.J.J.); MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (T.R.G., D.A.L., G.D.S.); Department of Women's Cancer, Institute for Women's Health, UCL, London, United Kingdom (A.G.-M., A.R., U.M.); Department of Clinical Epidemiology, Leiden University Medical Center, The Netherlands (R.d.M., D.O.M.-K.); Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands (R.N., S.T.); Interuniversity Cardiology Institute Netherlands, Utrecht (W.J.); Departments of Neurology and Public Health Sciences, University of Virginia, Charlottesville (B.B.W.); Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands (D.O.M.-K.); BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, United Kingdom (N.S.); Department of Epidemiology and Public Health, University College London, United Kingdom (M.K.); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom (F.D.); Department of Health Sciences, University of Leicester, United Kingdom (F.D.); Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute Building, University of Oxford, United Kingdom (M.V.H.); Medical Research Council Population Health Research Unit at the University of Oxford, United Kingdom (M.V.H.); and National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals, United Kingdom (M.V.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515354PMC
June 2017

Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study.

J Clin Oncol 2017 May 27;35(13):1411-1420. Epub 2017 Feb 27.

Adam N. Rosenthal, Lindsay S.M. Fraser, Susan Philpott, Ranjit Manchanda, Matthew Burnell, Philip Badman, Richard Hadwin, Ivana Rizzuto, Andy Ryan, Robert Liston, Jeremy Ford, Richard Gunu, Usha Menon, and Ian J. Jacobs, University College London Elizabeth Garrett Anderson Institute for Women's Health; Elizabeth Benjamin, University College London; Naveena Singh, Barts Health National Health Service Trust; Ranjit Manchanda, Barts Cancer Institute, Queen Mary University of London; Anne Dawnay, University College London Hospital; James Mackay, The University College London Cancer Institute, London; D. Gareth Evans, University of Manchester, St Mary's Hospital Manchester, Manchester; Diana M. Eccles, Southampton General Hospital, Southampton, United Kingdom; Steven J. Skates, Massachusetts General Hospital and Harvard Medical School, Boston, MA; and Ian J. Jacobs, University of New South Wales Australia, Sydney, New South Wales, Australia.

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http://ascopubs.org/doi/10.1200/JCO.2016.69.9330
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http://dx.doi.org/10.1200/JCO.2016.69.9330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455461PMC
May 2017

Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples.

Br J Cancer 2017 Feb 12;116(4):501-508. Epub 2017 Jan 12.

Department of Women's Cancer, Institute for Women's Health, University College London, London, W1T 7DN, UK.

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http://dx.doi.org/10.1038/bjc.2016.433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318971PMC
February 2017

Novel risk models for early detection and screening of ovarian cancer.

Oncotarget 2017 Jan;8(1):785-797

Stoller Biomarker Discovery Centre and Pathology Node, Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.18632/oncotarget.13648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352196PMC
January 2017

Ovarian Cancer Follow-up: A Preliminary Comparison of 2 Approaches.

Int J Gynecol Cancer 2017 01;27(1):59-68

*Department of Women's Cancer, The UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London, London; †Centre for Biostatistics, The University of Manchester, Manchester; ‡University College London Hospitals (UCLH) Gynaecological Cancer Centre; §Department of Applied Health Research, University College London; ‖Cancer Research UK and UCL Cancer Trials Centre, University College London, London, United Kingdom; and ¶University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1097/IGC.0000000000000877DOI Listing
January 2017

Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset.

Biomed Res Int 2015 24;2015:681416. Epub 2015 Dec 24.

Women's Cancer, Institute for Women's Health, University College London, Gower Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1155/2015/681416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706857PMC
October 2016

Protein Z: A putative novel biomarker for early detection of ovarian cancer.

Int J Cancer 2016 Jun 19;138(12):2984-92. Epub 2016 Feb 19.

Stoller Biomarker Discovery Centre and Pathology Node, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/ijc.30020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840324PMC
June 2016

Reply to P.F. Pinsky, C.P. Crum, and M.W. McIntosh et al.

J Clin Oncol 2016 Jan 16;34(2):201-2. Epub 2015 Nov 16.

University College London, London, United Kingdom; and University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.2015.64.1365DOI Listing
January 2016

Ovarian Cancer Follow-up: A Preliminary Comparison of 2 Approaches.

Int J Gynecol Cancer 2016 Jan;27(1):59-68

Department of Women's Cancer, The UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London, London.

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http://dx.doi.org/10.1097/IGC.0000000000000877DOI Listing
January 2016

Psychosocial Factors Associated With Withdrawal From the United Kingdom Collaborative Trial of Ovarian Cancer Screening After 1 Episode of Repeat Screening.

Int J Gynecol Cancer 2015 Oct;25(8):1519-25

*Sussex Health Outcomes Research & Education in Cancer (SHORE-C), University of Sussex, Brighton, East Sussex, UK; †Public Health and Primary Care, University of Cambridge, Cambridge, UK; ‡Women's Cancer, Institute for Women's Health, University College London, London, UK; §Chancellery Building, UNSW, Sydney NSW, Australia; and ∥MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK.

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http://dx.doi.org/10.1097/IGC.0000000000000507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582418PMC
October 2015

Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.

J Clin Oncol 2015 Jun 11;33(18):2062-71. Epub 2015 May 11.

Usha Menon, Andy Ryan, Jatinderpal Kalsi, Aleksandra Gentry-Maharaj, Mariam Habib, Sophia Apostolidou, Matthew Burnell, Susan Davies, Richard Gunu, Martin Widschwendter, Elizabeth Benjamin, Mahesh Parmar, and Ian Jacobs, University College London; Anne Dawnay and Tim Mould, University College London Hospital; Naveena Singh, Barts and the London School of Medicine and Dentistry; David Oram and Karina Reynolds, St Bartholomew's Hospital; Alistair McGuire, London School of Economics; Stuart Campbell, Create Health Clinic; Aarti Sharma, University Hospital of Wales; Nazar N. Amso, Cardiff University, Cardiff; Keith Godfrey, Queen Elizabeth Hospital, Gateshead; Alberto Lopes, Royal Cornwall Hospital, Truro; Jonathan Herod, Liverpool Women's Hospital, Liverpool; Karin Williamson, Nottingham City Hospital, Nottingham; Mourad W. Seif, St Mary's Hospital, Manchester; Howard Jenkins and Ian Scott, Royal Derby Hospital, Derby; Robert Woolas, Queen Alexandra Hospital, Portsmouth; John B. Murdoch, St Michael's Hospital, Bristol; Stephen Dobbs, Belfast City Hospital, Belfast; Simon Leeson, Llandudno Hospital, Ysbyty Gwynedd; Derek Cruickshank, James Cook University Hospital, Middlesbrough; Lesley Fallowfield, University of Sussex, Falmer, United Kingdom; Steven J. Skates, Massachusetts General Hospital and Harvard Medical School, Boston, MA; and Ian Jacobs, UNSW Australia, Sydney, NSW, Australia.

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http://ascopubs.org/doi/10.1200/JCO.2014.59.4945
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http://dx.doi.org/10.1200/JCO.2014.59.4945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463475PMC
June 2015

Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy: a nested United Kingdom Collaborative Trial of Ovarian Cancer Screening cohort study.

Menopause 2015 Apr;22(4):384-90

From the 1Gynaecological Cancer Research Centre, Department of Women's Cancer, Institute for Women's Health, University College London, London, UK; 2Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK; and 3Department of Psychology, Institute of Psychiatry, Guy's Campus, King's College London, London, UK.

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https://insights.ovid.com/crossref?an=00042192-201504000-000
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http://dx.doi.org/10.1097/GME.0000000000000330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470524PMC
April 2015

Identifying hopelessness in population research: a validation study of two brief measures of hopelessness.

BMJ Open 2014 May 30;4(5):e005093. Epub 2014 May 30.

Department of Women's Cancer, UCL Institute for Women's Health and NIHR University College London Hospitals Biomedical Research Centre, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2014-005093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039863PMC
May 2014

Work-related violence against educators in Minnesota: rates and risks based on hours exposed.

J Safety Res 2013 Feb 8;44:73-85. Epub 2013 Jan 8.

Regional Injury Prevention Research Center and Center for Violence Prevention and Control, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, 1260 Mayo Building, Mayo Mail Code 807, 420 Delaware St. SE, Minneapolis, MN 55455, United States.

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http://dx.doi.org/10.1016/j.jsr.2012.12.005DOI Listing
February 2013

Distribution of microsatellite instability in Danish ovarian tumor patients and the prognostic value in ovarian cancer patients.

Oncol Res 2008 ;17(1):43-9

Gynaecologic Clinic, The Juliane Marie Centre, Rigshospitalet, University of Copenhagen, Copenhagen O, DK-2100, Denmark.

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http://dx.doi.org/10.3727/096504008784046090DOI Listing
July 2008

OSPACS: Ultrasound image management system.

Source Code Biol Med 2008 Jun 20;3:11. Epub 2008 Jun 20.

Gynaecological Cancer Research Laboratories, UCL EGA Institute for Women's Health, University College London, Paul O'Gorman Building, Gower Street, London WC1E 6BT, UK.

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http://scfbm.biomedcentral.com/articles/10.1186/1751-0473-3-
Publisher Site
http://dx.doi.org/10.1186/1751-0473-3-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442597PMC
June 2008

Decline in use of hormone therapy among postmenopausal women in the United Kingdom.

Menopause 2007 May-Jun;14(3 Pt 1):462-7

Department of Gynaecological Oncology, UCL Institute for Women's Health, London, UK.

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http://dx.doi.org/10.1097/01.gme.0000243569.70946.9dDOI Listing
July 2007

A molecular genetic and statistical approach for the diagnosis of dual-site cancers.

J Natl Cancer Inst 2004 Oct;96(19):1441-6

Gynaecology Cancer Research Unit, St. Bartholomew's and The London, Queen Mary's School of Medicine and Dentistry, University of London, London, UK.

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http://dx.doi.org/10.1093/jnci/djh272DOI Listing
October 2004

Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option.

Clin Cancer Res 2004 Sep;10(18 Pt 1):6222-30

Department of Pathology, University Medical Centre St. Radboud, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0823DOI Listing
September 2004

Loss of heterozygosity on the X chromosome is an independent prognostic factor in ovarian carcinoma: from the Danish "MALOVA" Ovarian Carcinoma Study.

Cancer 2004 Jun;100(11):2387-95

Department of Viruses, Hormones and Cancer, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/cncr.20213DOI Listing
June 2004

Molecular assessment of depth of myometrial invasion in stage I endometrial cancer: a model based on K-ras mutation analysis.

Gynecol Oncol 2003 Oct;91(1):218-25

ICRF Translational Oncology Laboratory, St. Bartholomew's and the Royal London Medical and Dental School, Charterhouse Square, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.1016/s0090-8258(03)00505-5DOI Listing
October 2003

A soluble isoform of the rhesus monkey nonclassical MHC class I molecule Mamu-AG is expressed in the placenta and the testis.

J Immunol 2002 Jul;169(2):673-83

Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, WI 53715, USA.

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http://dx.doi.org/10.4049/jimmunol.169.2.673DOI Listing
July 2002

Molecular evidence of a common clonal origin and subsequent divergent clonal evolution in vulval intraepithelial neoplasia, vulval squamous cell carcinoma and lymph node metastases.

Int J Cancer 2002 Jun;99(4):549-54

Gynaecological Oncology Unit, St. Bartholomew's and Royal London Hospitals Medical College, Queen Mary and Westfield College, Charterhouse Square, London EC1M 6GM, UK.

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http://dx.doi.org/10.1002/ijc.10362DOI Listing
June 2002

Loss of heterozygosity and allelic imbalance in apocrine metaplasia of the breast: microdissection microsatellite analysis.

J Pathol 2002 Mar;196(3):287-91

Department of Histopathology, St. Bartholomew's Hospital, St. Bartholomew's and the Royal London School of Medicine and Dentistry, University of London, West Smithfield, London EC1A 7BE, UK.

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http://dx.doi.org/10.1002/path.1043DOI Listing
March 2002