Andrzej S Krolewski

Andrzej S Krolewski

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Andrzej S Krolewski

Publications by authors named "Andrzej S Krolewski"

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A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

Diabetes 2018 07 27;67(7):1414-1427. Epub 2018 Apr 27.

Wellcome Centre Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db17-0914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014557PMC
July 2018

Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development.

Kidney Int 2018 05 2;93(5):1198-1206. Epub 2018 Feb 2.

Section on Genetics and Epidemiology, Research Divisions, Joslin Diabetes Center, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911430PMC
May 2018

Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes.

Diabetes 2018 05 16;67(5):1013-1023. Epub 2018 Feb 16.

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA

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http://dx.doi.org/10.2337/db17-1207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910001PMC
May 2018

Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease.

Kidney Int 2017 07 7;92(1):258-266. Epub 2017 Apr 7.

Section on Genetics and Epidemiology, Research Divisions, Joslin Diabetes Center, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00852538173011
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http://dx.doi.org/10.1016/j.kint.2017.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796779PMC
July 2017

Fast renal decline to end-stage renal disease: an unrecognized feature of nephropathy in diabetes.

Kidney Int 2017 06 31;91(6):1300-1311. Epub 2017 Mar 31.

Research Division of Joslin Diabetes Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.kint.2016.10.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429989PMC
June 2017

Tumor necrosis factor receptors 1 and 2 are associated with early glomerular lesions in type 2 diabetes.

Kidney Int 2016 Jan 4;89(1):226-34. Epub 2016 Jan 4.

Research Division, Joslin Diabetes Center, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ki.2015.278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805514PMC
January 2016

Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in Type 1 Diabetes.

Diabetes 2015 Sep 30;64(9):3285-93. Epub 2015 Apr 30.

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA Department of Medicine, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.2337/db15-0116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542435PMC
September 2015

Cardiac autonomic neuropathy and early progressive renal decline in patients with nonmacroalbuminuric type 1 diabetes.

Clin J Am Soc Nephrol 2015 Jul 19;10(7):1136-44. Epub 2015 Jun 19.

Division of Endocrinology and Metabolism, Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada;

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http://dx.doi.org/10.2215/CJN.11441114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491301PMC
July 2015

Differential Gene Expression in Diabetic Nephropathy in Individuals With Type 1 Diabetes.

J Clin Endocrinol Metab 2015 Jun 14;100(6):E876-82. Epub 2015 Apr 14.

Departments of Medicine and Pediatrics (M.L.C., M.M.), and Pediatrics and Laboratory Medicine and Pathology (Y.K.), University of Minnesota, Minneapolis, Minnesota 55455; Joslin Diabetes Center (A.B.G., A.S.K.), Harvard Medical School, Boston, Massachusetts 02115; Department of Genetics (J.H.M.), Institute for Biomedical Informatics, Department of Biostatistics and Epidemiology, Perelman School of Medicine, Dartmouth College, Hanover, New Hampshire 03755; Departments of Public Health Sciences (S.S.R.), and Bioinformatics and Genetics (J.C.M.), University of Virginia, Charlottesville, Virginia 22908; Department of Genetics (D.K.), Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455; and JDRF (H.N.), New York, New York 10004.

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http://dx.doi.org/10.1210/jc.2014-4465DOI Listing
June 2015

Progressive renal decline: the new paradigm of diabetic nephropathy in type 1 diabetes.

Diabetes Care 2015 Jun;38(6):954-62

Research Division of Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.2337/dc15-0184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439536PMC
June 2015

Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes.

Kidney Int 2015 Apr 1;87(4):812-9. Epub 2014 Oct 1.

1] Research Division, Joslin Diabetes Center, Boston, Massachusetts, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00852538153020
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http://dx.doi.org/10.1038/ki.2014.330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382420PMC
April 2015

Improved glycemic control and risk of ESRD in patients with type 1 diabetes and proteinuria.

J Am Soc Nephrol 2014 Dec 5;25(12):2916-25. Epub 2014 Jun 5.

Research and Clinic Divisions at Joslin Diabetes Center and Department of Medicine, Brigham and Women Hospital, Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.1681/ASN.2013091002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243344PMC
December 2014

Progressive renal decline as the major feature of diabetic nephropathy in type 1 diabetes.

Clin Exp Nephrol 2014 Aug 12;18(4):571-83. Epub 2013 Nov 12.

Section on Genetics and Epidemiology, Research Division of Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA,

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http://dx.doi.org/10.1007/s10157-013-0900-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018428PMC
August 2014

Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.

Kidney Int 2014 May 15;85(5):1214-24. Epub 2014 Jan 15.

1] Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, Massachussetts, USA [2] Department of Medicine, Harvard Medical School, Boston, Massachussetts, USA.

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http://dx.doi.org/10.1038/ki.2013.497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072128PMC
May 2014

Diabetic nephropathy: is ESRD its only heritable phenotype?

J Am Soc Nephrol 2013 Oct 12;24(10):1505-7. Epub 2013 Sep 12.

Research Division, Joslin Diabetes Center, Boston, Massachusetts; and.

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http://dx.doi.org/10.1681/ASN.2013070769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785288PMC
October 2013

The genetic risk of kidney disease in type 2 diabetes.

Med Clin North Am 2013 Jan 7;97(1):91-107. Epub 2012 Dec 7.

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.mcna.2012.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539136PMC
January 2013

Serum concentration of cystatin C and risk of end-stage renal disease in diabetes.

Diabetes Care 2012 Nov 30;35(11):2311-6. Epub 2012 Jul 30.

Research and Clinic Divisions, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.2337/dc11-2220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476893PMC
November 2012

High risk of ESRD in type 1 diabetes: call for action: introduction.

Semin Nephrol 2012 Sep;32(5):405-6

Research Divison, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.semnephrol.2012.07.001DOI Listing
September 2012

High risk of ESRD in type 1 diabetes: new strategies are needed to retard progressive renal function decline.

Semin Nephrol 2012 Sep;32(5):407-14

Research Division of the Joslin Diabetes Center, Harvard Medicial School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.semnephrol.2012.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474985PMC
September 2012

Elevated urinary excretion of immunoglobulins in nonproteinuric patients with type 1 diabetes.

Am J Physiol Renal Physiol 2012 Jul 18;303(1):F157-62. Epub 2012 Apr 18.

Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1152/ajprenal.00443.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431142PMC
July 2012

Diabetes: Lowering serum uric acid levels to prevent kidney failure.

Nat Rev Nephrol 2011 Aug 2;7(9):495-6. Epub 2011 Aug 2.

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http://dx.doi.org/10.1038/nrneph.2011.107DOI Listing
August 2011

Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes.

Mol Genet Metab 2011 May 14;103(1):60-5. Epub 2011 Jan 14.

Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ymgme.2011.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081941PMC
May 2011

Risk for ESRD in type 1 diabetes remains high despite renoprotection.

J Am Soc Nephrol 2011 Mar 25;22(3):545-53. Epub 2011 Feb 25.

Section on Genetics & Epidemiology, Research and Clinic Divisions, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1681/ASN.2010040354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060448PMC
March 2011

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.

J Clin Invest 2010 Aug 1;120(8):2876-88. Epub 2010 Jul 1.

Section of Islet Cell and Regenerative Medicine, Department of Medicine, Harvard Medical School, Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215, USA.

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http://www.jci.org/articles/view/36849
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http://dx.doi.org/10.1172/JCI36849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912176PMC
August 2010

Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.

Diabetes 2009 Nov 3;58(11):2698-702. Epub 2009 Aug 3.

Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/db09-0641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768169PMC
November 2009

Renal hyperfiltration and the development of microalbuminuria in type 1 diabetes.

Diabetes Care 2009 May 5;32(5):889-93. Epub 2009 Feb 5.

Research Division, Joslin Diabetes Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/dc08-1560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671109PMC
May 2009

Early nephropathy in type 1 diabetes: the importance of early renal function decline.

Curr Opin Nephrol Hypertens 2009 May;18(3):233-40

Division of Endocrinology and Metabolism, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/MNH.0b013e3283293db1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830878PMC
May 2009

Between hyperfiltration and impairment: demystifying early renal functional changes in diabetic nephropathy.

Diabetes Res Clin Pract 2008 Nov 11;82 Suppl 1:S46-53. Epub 2008 Oct 11.

Research Division, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.diabres.2008.09.018DOI Listing
November 2008

An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.

Kidney Int 2008 Aug 21;74(4):521-7. Epub 2008 May 21.

Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine,National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1038/ki.2008.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756185PMC
August 2008

Genetic variation at the SLC12A3 locus is unlikely to explain risk for advanced diabetic nephropathy in Caucasians with type 2 diabetes.

Nephrol Dial Transplant 2008 Jul 10;23(7):2260-4. Epub 2008 Feb 10.

Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1093/ndt/gfm946DOI Listing
July 2008

Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics.

J Am Soc Nephrol 2008 Apr 6;19(4):789-97. Epub 2008 Feb 6.

Section on Genetics & Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1681/ASN.2007050556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390964PMC
April 2008

Identification of a locus modulating serum C-reactive protein levels on chromosome 5p15.

Atherosclerosis 2008 Feb 7;196(2):863-70. Epub 2007 Mar 7.

Research Division, Joslin Diabetes Center, Section on Genetics & Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.01.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335172PMC
February 2008

Microalbuminuria and the risk for early progressive renal function decline in type 1 diabetes.

J Am Soc Nephrol 2007 Apr 28;18(4):1353-61. Epub 2007 Feb 28.

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1681/ASN.2006080872DOI Listing
April 2007

A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus.

Diabetes 2006 Sep;55(9):2660-3

Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.2337/db06-0496DOI Listing
September 2006

A novel framework for sib pair linkage analysis.

Am J Hum Genet 2006 Feb 8;78(2):222-30. Epub 2005 Dec 8.

Section on Genetics and Epidemiology, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1086/499827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380231PMC
February 2006

Early nephropathy in type 1 diabetes: a new perspective on who will and who will not progress.

Curr Diab Rep 2005 Dec;5(6):455-63

Section on Genetics and Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.1007/s11892-005-0055-7DOI Listing
December 2005

The fatty acid-binding protein-2 A54T polymorphism is associated with renal disease in patients with type 2 diabetes.

Diabetes 2005 Nov;54(11):3326-30

Endocrine Division, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

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http://dx.doi.org/10.2337/diabetes.54.11.3326DOI Listing
November 2005

Cystatin C and the risk of death.

N Engl J Med 2005 Aug;353(8):842-4; author reply 842-4

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August 2005

Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: results of a 4-year follow-up study.

J Am Soc Nephrol 2005 May 23;16(5):1404-12. Epub 2005 Mar 23.

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1681/ASN.2004100854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429917PMC
May 2005

Epidemic of end-stage renal disease in people with diabetes in the United States population: do we know the cause?

Kidney Int 2005 May;67(5):1684-91

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00265.xDOI Listing
May 2005

Evidence for different susceptibility genes for proteinuria and ESRD in type 2 diabetes.

Adv Chronic Kidney Dis 2005 Apr;12(2):155-69

Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1053/j.ackd.2005.02.002DOI Listing
April 2005

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23.

Diabetes 2004 May;53(5):1375-84

Research Division, Section on Genetics and Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.2337/diabetes.53.5.1375DOI Listing
May 2004

Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.

J Am Soc Nephrol 2003 Aug;14(8):2015-24

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/01.asn.0000077347.27669.5cDOI Listing
August 2003

Regression of microalbuminuria in type 1 diabetes.

N Engl J Med 2003 Jun;348(23):2285-93

Section on Genetics and Epidemiology, Research Division, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa021835
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http://dx.doi.org/10.1056/NEJMoa021835DOI Listing
June 2003

TGF-beta 1 as a genetic susceptibility locus for advanced diabetic nephropathy in type 1 diabetes mellitus: an investigation of multiple known DNA sequence variants.

Am J Kidney Dis 2003 Jan;41(1):22-8

Section on Genetics and Epidemiology, Joslin Diabetes Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1053/ajkd.2003.50011DOI Listing
January 2003

Minor effect of GLUT1 polymorphisms on susceptibility to diabetic nephropathy in type 1 diabetes.

Diabetes 2002 Jul;51(7):2264-9

Section on Genetics and Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

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http://dx.doi.org/10.2337/diabetes.51.7.2264DOI Listing
July 2002

Genetic studies of late diabetic complications: the overlooked importance of diabetes duration before complication onset.

Diabetes 2002 Jun;51(6):1655-62

Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215-5397, USA.

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http://dx.doi.org/10.2337/diabetes.51.6.1655DOI Listing
June 2002

Polymorphism in ecto-nucleotide pyrophosphatase/phosphodiesterase 1 gene (ENPP1/PC-1) and early development of advanced diabetic nephropathy in type 1 diabetes.

Diabetes 2002 Apr;51(4):1188-93

Research Division, Joslin Diabetes Center, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.2337/diabetes.51.4.1188DOI Listing
April 2002