Andrew Worth

Andrew Worth

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Insights into in vitro biokinetics using Virtual Cell Based Assay simulations.

ALTEX 2019 28;36(3):447-461. Epub 2019 Mar 28.

European Commission, Joint Research Centre, Ispra, Italy.

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http://dx.doi.org/10.14573/altex.1812101DOI Listing
January 2020

Application of new statistical distribution approaches for environmental mixture risk assessment: A case study.

Sci Total Environ 2019 Nov 21;693:133510. Epub 2019 Jul 21.

European Commission, Joint Research Centre, Via E. Fermi, 2749, 21027 Ispra, VA, Italy.

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http://dx.doi.org/10.1016/j.scitotenv.2019.07.316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839615PMC
November 2019

Canine Degenerative Lumbosacral Stenosis: Prevalence, Impact And Management Strategies.

Vet Med (Auckl) 2019 19;10:169-183. Epub 2019 Nov 19.

Texas A&M Veterinary Medical Teaching Hospital, College Station, TX 77845, USA.

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http://dx.doi.org/10.2147/VMRR.S180448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875490PMC
November 2019

Development and analysis of an adverse outcome pathway network for human neurotoxicity.

Arch Toxicol 2019 10 23;93(10):2759-2772. Epub 2019 Aug 23.

European Commission, Joint Research Centre (JRC), Ispra, Italy.

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http://dx.doi.org/10.1007/s00204-019-02551-1DOI Listing
October 2019

The influence of inter-particle forces on diffusion at the nanoscale.

Sci Rep 2019 Sep 3;9(1):12689. Epub 2019 Sep 3.

Faculty of Science and Engineering, University of Liverpool, Liverpool, L69 3GH, United Kingdom.

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http://dx.doi.org/10.1038/s41598-019-48754-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722115PMC
September 2019

Carcinogenicity assessment: Addressing the challenges of cancer and chemicals in the environment.

Environ Int 2019 07 9;128:417-429. Epub 2019 May 9.

European Commission, Joint Research Centre (JRC), Ispra, Italy.

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http://dx.doi.org/10.1016/j.envint.2019.04.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520474PMC
July 2019

Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives.

Environ Int 2019 05 8;126:659-671. Epub 2019 Mar 8.

Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environment et travail), UMR_S 1085, F-35000 Rennes, France.

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http://dx.doi.org/10.1016/j.envint.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441651PMC
May 2019

Computer-Assisted Surgery Using 3D Printed Saw Guides for Acute Correction of Antebrachial Angular Limb Deformities in Dogs.

Vet Comp Orthop Traumatol 2019 May 9;32(3):241-249. Epub 2019 Apr 9.

Axia Design Group Ltd, Napier, New Zealand.

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http://dx.doi.org/10.1055/s-0039-1678701DOI Listing
May 2019

Investigating cell type specific mechanisms contributing to acute oral toxicity.

ALTEX 2019 12;36(1):39-64. Epub 2018 Jul 12.

EU Commission Joint Research Centre (JRC), Ispra, Italy.

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http://dx.doi.org/10.14573/altex.1805181DOI Listing
April 2019

Regulatory assessment and risk management of chemical mixtures: challenges and ways forward.

Crit Rev Toxicol 2019 02 1;49(2):174-189. Epub 2019 Apr 1.

European Commission, Joint Research Centre (JRC) , Ispra , Italy.

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http://dx.doi.org/10.1080/10408444.2019.1579169DOI Listing
February 2019

Use of continuous sciatic nerve block for a week as part of a multidisciplinary approach for limb salvage in two dogs.

Vet Anaesth Analg 2019 01 20;46(1):141-143. Epub 2018 Sep 20.

The Royal Veterinary College, Hatfield, UK.

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http://dx.doi.org/10.1016/j.vaa.2018.09.002DOI Listing
January 2019

The Site of Bone Marrow Acquisition Affects the Myeloid to Erythroid Ratio in Apparently Healthy Dogs.

Vet Pathol 2018 11 25;55(6):853-860. Epub 2018 Jun 25.

3 Department of Microbiology, Immunology & Pathology, Colorado State University, Fort Collins, CO, USA.

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http://dx.doi.org/10.1177/0300985818780469DOI Listing
November 2018

Repeatability of Three-Dimensional Computed Tomographic Volumetric Measurement of Lumbosacral Intervertebral Foramina in German Shepherd Dogs.

Vet Comp Orthop Traumatol 2018 Sep 23;31(5):339-343. Epub 2018 Aug 23.

Massey University Veterinary Teaching Hospital, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.1055/s-0038-1660873DOI Listing
September 2018

Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.

Cell Metab 2018 Jun 10;27(6):1263-1280.e6. Epub 2018 May 10.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990482PMC
June 2018

Bioorthogonal pro-metabolites for profiling short chain fatty acylation.

Chem Sci 2018 Feb 8;9(5):1236-1241. Epub 2017 Dec 8.

Chemical Biology Laboratory , Center for Cancer Research , National Cancer Institute , National Institutes of Health , Frederick , MD 21702 , USA . Email:

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http://dx.doi.org/10.1039/c7sc00247eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885804PMC
February 2018

Medium-Term Outcome and CT Assessment of Lateral Foraminotomy at the Lumbosacral Junction in Dogs with Degenerative Lumbosacral Stenosis.

Vet Comp Orthop Traumatol 2018 Jan 11;31(1):37-43. Epub 2018 Jan 11.

Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, Manawatu, New Zealand.

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http://dx.doi.org/10.3415/vcot-17-05-0061DOI Listing
January 2018

Multiscale modelling approaches for assessing cosmetic ingredients safety.

Toxicology 2017 12 4;392:130-139. Epub 2016 Jun 4.

European Commission Joint Research Centre, Institute for Health and Consumer Protection, Systems Toxicology Unit, Via Enrico Fermi 2749, Ispra, VA, Italy.

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http://dx.doi.org/10.1016/j.tox.2016.05.026DOI Listing
December 2017

In Silico Models for Acute Systemic Toxicity.

Methods Mol Biol 2016 ;1425:177-200

Department of QSAR & Molecular Modeling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.

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http://dx.doi.org/10.1007/978-1-4939-3609-0_10DOI Listing
December 2017

The virtual cell based assay: Current status and future perspectives.

Toxicol In Vitro 2017 Dec 18;45(Pt 2):258-267. Epub 2017 Jan 18.

Chemical Safety and Alternative Methods Unit incorporating EURL ECVAM, Directorate Health, Consumers and Reference Materials, European Commission, Joint Research Centre, Ispra, Italy.

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http://dx.doi.org/10.1016/j.tiv.2017.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742635PMC
December 2017

The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data - A case study with caffeine.

Toxicology 2017 12 10;392:119-129. Epub 2017 Mar 10.

Directorate Health, Consumers and Reference Materials, European Commission, Joint Research Centre, Ispra, Italy.

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http://dx.doi.org/10.1016/j.tox.2017.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699174PMC
December 2017

Automated workflows for modelling chemical fate, kinetics and toxicity.

Toxicol In Vitro 2017 Dec 18;45(Pt 2):249-257. Epub 2017 Mar 18.

Chemical Safety and Alternative Methods Unit, EURL ECVAM, Directorate F - Health, Consumers and Reference Materials, Joint Research Centre, European Commission, Ispra, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S08872333173006
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http://dx.doi.org/10.1016/j.tiv.2017.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745146PMC
December 2017

From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling.

Toxicol In Vitro 2017 Dec 27;45(Pt 2):241-248. Epub 2017 Jun 27.

Chemical Safety and Alternative Methods Unit, EURL ECVAM, Directorate F - Health, Consumers and Reference Materials, Joint Research Centre, European Commission, Ispra, Italy.

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http://dx.doi.org/10.1016/j.tiv.2017.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742636PMC
December 2017

Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes.

Toxicol In Vitro 2017 Dec 11;45(Pt 2):222-232. Epub 2017 Sep 11.

European Commission, Joint Research Centre, Directorate F - Health, Consumers and Reference Materials, Chemical Safety and Alternative Methods Unit, EURL ECVAM, Ispra, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2017.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745147PMC
December 2017

Metabolic tracing analysis reveals substrate-specific metabolic deficits in platelet storage lesion.

Transfusion 2017 11 23;57(11):2683-2689. Epub 2017 Aug 23.

A.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/trf.14292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787404PMC
November 2017

Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications.

Regul Toxicol Pharmacol 2017 Nov 1;90:104-115. Epub 2017 Sep 1.

European Commission, Joint Research Centre, Directorate Health, Consumers and Reference Materials, Via E Fermi 2749, 21027 Ispra, Italy.

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http://dx.doi.org/10.1016/j.yrtph.2017.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656087PMC
November 2017

Effect of a calcaneo-tibial screw on medial and lateral stability of the canine tarsocrural joint ex vivo.

Vet Comp Orthop Traumatol 2017 Sep 1;30(5):331-338. Epub 2017 Aug 1.

Kevin R. Frame, BVSc, 3310 Emerald Pointe Drive, Apt. 105B, Hollywood, Florida 33021, United States, Phone: +1 303 550 5440, E-mail:

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http://dx.doi.org/10.3415/VCOT-16-12-0160DOI Listing
September 2017

Quantitative structure-skin permeability relationships.

Toxicology 2017 07 21;387:27-42. Epub 2017 Jun 21.

School of Pharmacy and Chemistry, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, England, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2017.06.008DOI Listing
July 2017

Validation of Computational Methods.

Adv Exp Med Biol 2016;856:165-187

Toxicology and Environmental Research and Consulting (TERC), Environment, Health and Safety (EH&S), The Dow Chemical Company, Horgen, Zurich, 8810, Switzerland.

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http://dx.doi.org/10.1007/978-3-319-33826-2_6DOI Listing
June 2017

Integrated Approaches to Testing and Assessment.

Adv Exp Med Biol 2016;856:317-342

Dupont Haskell Global Centers for Health and Environmental Sciences, Newark, DE, USA.

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http://dx.doi.org/10.1007/978-3-319-33826-2_13DOI Listing
June 2017

Computed tomographic evaluation of dynamic alteration of the canine lumbosacral intervertebral neurovascular foramina.

Vet Surg 2017 Feb 11;46(2):255-264. Epub 2017 Jan 11.

Massey University Veterinary Teaching Hospital, Palmerston North, New Zealand.

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http://dx.doi.org/10.1111/vsu.12599DOI Listing
February 2017

Can currently available non-animal methods detect pre and pro-haptens relevant for skin sensitization?

Regul Toxicol Pharmacol 2016 Dec 26;82:147-155. Epub 2016 Aug 26.

European Commission, Joint Research Centre, Directorate F - Health, Consumers and Reference Materials, Chemical Safety and Alternative Methods Unit, Ispra, VA, Italy.

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http://dx.doi.org/10.1016/j.yrtph.2016.08.007DOI Listing
December 2016

Regulatory assessment of chemical mixtures: Requirements, current approaches and future perspectives.

Regul Toxicol Pharmacol 2016 Oct 20;80:321-34. Epub 2016 May 20.

European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Systems Toxicology Unit and EURL ECVAM, Via Enrico Fermi 2749, 21027, Ispra, VA, Italy.

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http://dx.doi.org/10.1016/j.yrtph.2016.05.020DOI Listing
October 2016

ACCURACY OF RADIOGRAPHIC DETECTION OF THE CRANIAL MARGIN OF THE DORSAL LAMINA OF THE CANINE SACRUM.

Vet Radiol Ultrasound 2015 Nov-Dec;56(6):579-88. Epub 2015 Aug 25.

Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.1111/vru.12282DOI Listing
August 2016

Analysis of the Local Lymph Node Assay (LLNA) variability for assessing the prediction of skin sensitisation potential and potency of chemicals with non-animal approaches.

Toxicol In Vitro 2016 Aug 13;34:220-228. Epub 2016 Apr 13.

Joint Research Centre, European Commission, Ispra, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2016.04.008DOI Listing
August 2016

Diisopropylethylamine/hexafluoroisopropanol-mediated ion-pairing ultra-high-performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite analysis: utility for studying cellular metabolism.

Rapid Commun Mass Spectrom 2016 08;30(16):1835-45

Penn SRP and Center for Excellence in Environmental Toxicology, Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1002/rcm.7667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970762PMC
August 2016

Evaluation of non-animal methods for assessing skin sensitisation hazard: A Bayesian Value-of-Information analysis.

Altern Lab Anim 2016 Jul;44(3):255-69

BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany.

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http://dx.doi.org/10.1177/026119291604400309DOI Listing
July 2016

Exploring waiving opportunities for mammalian acute systemic toxicity tests.

Altern Lab Anim 2016 Jul;44(3):271-9

European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), European Commission, Joint Research Centre, Ispra, Italy.

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http://dx.doi.org/10.1177/026119291604400306DOI Listing
July 2016

Stable isotopes and LC-MS for monitoring metabolic disturbances in Friedreich's ataxia platelets.

Bioanalysis 2015 ;7(15):1843-55

Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4155/bio.15.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620983PMC
May 2016

LC-MS Analysis of Human Platelets as a Platform for Studying Mitochondrial Metabolism.

J Vis Exp 2016 Apr 4(110):e53941. Epub 2016 Apr 4.

Center for Cancer Pharmacology, University of Pennsylvania; Center for Excellence in Environmental Toxicology, University of Pennsylvania;

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http://dx.doi.org/10.3791/53941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841355PMC
April 2016

Assessing herbal products with health claims.

Crit Rev Food Sci Nutr 2015 ;55(13):1918-28

a European Commission, Joint Research Centre (JRC), Institute for Health and Consumer Protection (IHCP), Public Health Policy Support Unit, Ispra (VA) , Italy.

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http://dx.doi.org/10.1080/10408398.2012.726661DOI Listing
February 2016

Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure.

Bioanalysis 2015 ;7(9):1157-73

1Penn SRP Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.4155/bio.15.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487641PMC
February 2016

Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.

Oncotarget 2016 Feb;7(8):9353-67

Molecular Oncology Laboratories, Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.18632/oncotarget.6981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891045PMC
February 2016

Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.

Circulation 2016 Feb 27;133(8):706-16. Epub 2016 Jan 27.

From Cardiovascular Institute University of Pennsylvania Perelman School of Medicine, Smilow Translational Research Center, Philadelphia, PA (K.C.B., J.B., A.J., K.B.M., J.E.R.); A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA (N.W.S.); and Center of Cancer Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (M.A., C.M., A.J.W., L.L.W., I.A.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.017545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779339PMC
February 2016

Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine.

J Biol Chem 2016 Jan 31;291(1):42-57. Epub 2015 Oct 31.

From the Penn Superfund Research and Training Program Center, Center of Excellence in Environmental Toxicology, and Department of Systems Pharmacology and Translational Therapeutics and

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http://dx.doi.org/10.1074/jbc.M115.697516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697178PMC
January 2016

A rule for designing safer nanomaterials: do not interfere with the cellular redox equilibrium.

Nanotoxicology 2015 May 16;9 Suppl 1:116-7. Epub 2013 Sep 16.

Risk Analysis of Products in Development, TNO , Zeist , The Netherlands , and.

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http://dx.doi.org/10.3109/17435390.2013.828109DOI Listing
May 2015

Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells.

Chem Res Toxicol 2015 May 8;28(5):948-54. Epub 2015 Apr 8.

∥A.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania 19104, United States.

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http://dx.doi.org/10.1021/tx500535cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721232PMC
May 2015

ATM couples replication stress and metabolic reprogramming during cellular senescence.

Cell Rep 2015 May 30;11(6):893-901. Epub 2015 Apr 30.

Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431925PMC
May 2015

Production of stable isotope-labeled acyl-coenzyme A thioesters by yeast stable isotope labeling by essential nutrients in cell culture.

Anal Biochem 2015 Apr 6;474:59-65. Epub 2015 Jan 6.

Penn SRP Center and Center of Excellence in Environmental Toxicology, Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2014.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413507PMC
April 2015

Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets.

J Lipid Res 2015 Jan 25;56(1):142-50. Epub 2014 Nov 25.

Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M055384
Publisher Site
http://dx.doi.org/10.1194/jlr.M055384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274062PMC
January 2015

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

Regul Toxicol Pharmacol 2014 Dec 27;70(3):629-40. Epub 2014 Sep 27.

DuPont Haskell Global Centers for Health and Environmental Sciences, Stine-Haskell 320/212, 1090 Elkton Road, Newark, DE 19711, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02732300140021
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http://dx.doi.org/10.1016/j.yrtph.2014.09.009DOI Listing
December 2014

Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop.

Mutat Res Genet Toxicol Environ Mutagen 2014 Dec 23;775-776:55-68. Epub 2014 Oct 23.

European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), Systems Toxicology Unit; Institute for Health and Consumer Protection (IHCP), European Commission - Joint Research Centre, TP 126, Via E. Fermi 2749, I-21027 Ispra, Va, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2014.10.005DOI Listing
December 2014

Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels.

J Biol Chem 2014 Sep 12;289(39):26895-903. Epub 2014 Aug 12.

From the Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.591354
Publisher Site
http://dx.doi.org/10.1074/jbc.M114.591354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175330PMC
September 2014

Stable isotope dilution liquid chromatography/mass spectrometry analysis of cellular and tissue medium- and long-chain acyl-coenzyme A thioesters.

Rapid Commun Mass Spectrom 2014 Aug;28(16):1840-8

Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, and Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4863, USA.

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http://dx.doi.org/10.1002/rcm.6958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286313PMC
August 2014

A tutorial for analysing the cost-effectiveness of alternative methods for assessing chemical toxicity: the case of acute oral toxicity prediction.

Altern Lab Anim 2014 May;42(2):115-27

Department of Social Sciences, Environmental Economics and Natural Resources Group, Wageningen University, Wageningen, The Netherlands.

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http://altweb.jhsph.edu/pubs/journals/atla/42_2/Norlen.pdf
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http://dx.doi.org/10.1177/026119291404200204DOI Listing
May 2014

Establishing the level of safety concern for chemicals in food without the need for toxicity testing.

Regul Toxicol Pharmacol 2014 Mar 5;68(2):275-96. Epub 2013 Sep 5.

European Commission - Joint Research Centre, Institute for Health & Consumer Protection, Ispra, Italy.

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http://dx.doi.org/10.1016/j.yrtph.2013.08.018DOI Listing
March 2014

Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential.

Toxicology 2013 Nov 16;313(1):15-23. Epub 2012 Nov 16.

CSIRO Materials Science and Engineering, Clayton, Australia; Monash Institute of Pharmaceutical Science, Parkville, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0300483X120039
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http://dx.doi.org/10.1016/j.tox.2012.11.005DOI Listing
November 2013

Computed tomographic method for measurement of inclination angles and motion of the sacroiliac joints in German Shepherd Dogs and Greyhounds.

Am J Vet Res 2013 Sep;74(9):1172-82

Institute of Veterinary, Animal and Biomedical Sciences, College of Veterinary Science, Massey University, Palmerston North 4442, New Zealand.

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http://dx.doi.org/10.2460/ajvr.74.9.1172DOI Listing
September 2013

Untargeted metabolomics from biological sources using ultraperformance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS).

J Vis Exp 2013 May 20(75):e50433. Epub 2013 May 20.

Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, Department of Pharmacology, University of Pennsylvania.

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http://dx.doi.org/10.3791/50433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711276PMC
May 2013

QSAR and metabolic assessment tools in the assessment of genotoxicity.

Methods Mol Biol 2013 ;930:125-62

Institute for Health and Consumer Protection, European Commission-Joint Research Centre, Ispra, VA, Italy.

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March 2013

Training needs for toxicity testing in the 21st century: a survey-informed analysis.

Altern Lab Anim 2012 Dec;40(6):313-20

Systems Toxicology Unit, Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Ispra, Varese, Italy.

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http://dx.doi.org/10.1177/026119291204000604DOI Listing
December 2012

Comparison between a novel bovine xenoimplant and autogenous cancellous bone graft in tibial tuberosity advancement.

Vet Surg 2012 Jul 25;41(5):559-67. Epub 2012 May 25.

Massey University Veterinary Teaching Hospital, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.

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http://doi.wiley.com/10.1111/j.1532-950X.2012.01003.x
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July 2012

Rapid prototype modeling and customized titanium plate fabrication for correction of a persistent hard palate defect in a dog.

J Am Vet Med Assoc 2012 Jun;240(11):1316-22

Veterinary Teaching Hospital, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.

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http://dx.doi.org/10.2460/javma.240.11.1316DOI Listing
June 2012

Recent advances in the molecular modeling of estrogen receptor-mediated toxicity.

Adv Protein Chem Struct Biol 2011 ;85:217-51

Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.

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February 2012

Use of computational tools in the field of food safety.

Regul Toxicol Pharmacol 2011 Aug 12;60(3):354-62. Epub 2011 May 12.

Institute for Health and Consumer Protection, European Commission-Joint Research Centre, Ispra (VA), Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S027323001100099
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August 2011

A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles.

Nanotoxicology 2011 Jun 15;5(2):228-35. Epub 2010 Jul 15.

Systems Toxicology Unit, Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Via Enrico Fermi 2749, Ispra, Varese, Italy.

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June 2011